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Kronuz 200 mg Injection 1's belongs to the class of medicines called antifungals used to treat fungal infections such as invasive aspergillosis and mucormycosis (in patients for whom Amphotericin B is not suitable). Invasive aspergillosis is an infection caused by Aspergillus fungus. It occurs by breathing and spreads from the lungs to the kidneys, brain, heart or skin. Mucormycosis is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems.
Kronuz 200 mg Injection 1's contains Isavuconazole which works by fungicidal actions by disrupting the biosynthesis of ergosterol,which are essential for their survival and kills fungus that causes infection.
Kronuz 200 mg Injection 1's will be administered by a healthcare professional; do not self-administer. Some people may experience headache, decreased appetite, sleepiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Most of these side effects of Kronuz 200 mg Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
If you are allergic to Kronuz 200 mg Injection 1's or any other medicines, please tell your doctor. Kronuz 200 mg Injection 1's is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Kronuz 200 mg Injection 1's. Avoid breastfeeding while taking Kronuz 200 mg Injection 1's. Drive only if you are alert after taking Kronuz 200 mg Injection 1's as it may cause drowsiness, confusion or dizziness. Avoid alcohol consumption while taking Kronuz 200 mg Injection 1's as it may increase the risk of liver damage.
Kronuz 200 mg Injection 1's is used in the treatment of Invasive aspergillosis and Mucormycosis. The detailed uses of Kronuz 200 mg Injection 1's are as follows:
Kronuz 200 mg Injection 1's contains Isavuconazole, a broad-spectrum antifungal that is effective against a wide variety of microorganisms. It inhibits the synthesis of fungal cell membranes that are essential for their survival. Thereby, Kronuz 200 mg Injection 1's kills or stops the growth of the fungus.
Unsafe
Avoid consumption of alcohol while taking Kronuz 200 mg Injection 1's as it may increase the risk of liver damage.
Consult your doctor
Kronuz 200 mg Injection 1's is not recommended during pregnancy except in patients with severe or potentially life-threatening fungal infections in whom Kronuz 200 mg Injection 1's may be used if the doctor thinks the benefits outweigh the risks. Therefore, please inform your doctor if you are pregnant or planning pregnancy.
Unsafe
Avoid breastfeeding while taking Kronuz 200 mg Injection 1's. Please inform your doctor if you are breastfeeding.
Caution
Drive only if you are alert after taking Kronuz 200 mg Injection 1's as it may cause drowsiness, confusion or dizziness.
Caution
Inform your doctor if you have liver problems before receiving Kronuz 200 mg Injection 1's as may worsen your condition. Your doctor may adjust the dose as required based on your condition.
Caution
The use of Kronuz 200 mg Injection 1's in patients with severe Kidney impairment is not established. Inform your doctor if you have kidney problems before receiving Kronuz 200 mg Injection 1's as may worsen your condition. Your doctor may adjust the dose as required based on your condition.
Unsafe
Kronuz 200 mg Injection 1's is not recommended for children below 18 years as the safety and effectiveness were not established.
Caution
Inform your doctor if you have heart problems before receiving Kronuz 200 mg Injection 1's, as it may worsen your condition. Your doctor may adjust the dose as required based on your condition.
Consult your doctor
Limited information available about the use of Kronuz 200 mg Injection 1's in geriatric patients. Please consult your physician.

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Keep Refrigerated. Do not freeze.
If you are allergic to Kronuz 200 mg Injection 1's or any other medicines, please tell your doctor. Kronuz 200 mg Injection 1's is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Kronuz 200 mg Injection 1's. Avoid breastfeeding while taking Kronuz 200 mg Injection 1's. Drive only if you are alert after taking Kronuz 200 mg Injection 1's as it may cause drowsiness, confusion or dizziness. Avoid alcohol consumption while taking Kronuz 200 mg Injection 1's as it may increase the risk of liver damage. If you experience severe blistering of the eyes, mouth, skin or genitals, seek immediate medical help.
Drug-Drug Interaction: Inform your doctor if you are taking anti-HIV drugs (ritonavir, efavirenz, etravirine), antibiotics (nafcillin), antitubercular drugs (rifabutin, rifampicin), medicine for rheumatoid arthritis (prednisone), immunosuppressants (tacrolimus, sirolimus, ciclosporin), antidiabetics (pioglitazone, metformin), anticonvulsants (carbamazepine, phenobarbital, phenytoin), antifungal (ketoconazole) or any other medicines before taking Kronuz 200 mg Injection 1's.
Drug-Food Interaction: Kronuz 200 mg Injection 1's may interact with St. John’s wort (herbal medicine to treat depression).
Drug-Disease Interaction: If you have liver or heart problems, inform your doctor before taking Kronuz 200 mg Injection 1's.
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Kronuz 200 mg Injection 1's is used to treat Invasive aspergillosis and Mucormycosis.
Kronuz 200 mg Injection 1's contains Isavuconazole which works by inhibiting the synthesis of fungal cell membranes which are essential for their survival. Thereby, Kronuz 200 mg Injection 1's kills or inhibits the growth of the fungus.
Mucormycosis is not contagious. Mucormycosis is a severe fungal infection of the skin or respiratory system that occurs in people with a weakened immune system.
Kronuz 200 mg Injection 1's may cause headaches as a common side effect. However, if the condition persists or worsens, please consult a doctor.
You are not recommended to take Kronuz 200 mg Injection 1's with ketoconazole as it may increase the levels of Kronuz 200 mg Injection 1's in your blood and increase the risk of side effects such as diarrhoea, vomiting, nausea or liver problems. However, please consult your doctor before taking Kronuz 200 mg Injection 1's with other medicines.
Kronuz 200 mg Injection 1's should be used with caution in patients with liver problems as Kronuz 200 mg Injection 1's may increase liver enzymes. Thus, monitoring of liver enzymes is advised while taking Kronuz 200 mg Injection 1's. However, you are recommended to inform your doctor if you have any liver problems.
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