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compositionComposition:CARBIDOPA-25MG+LEVODOPA-100MG
prescription
Prescription Medicine
info
LCD 125 Tablet 10's
LCD 125 Tablet 10's
LCD 125 Tablet 10's
LCD 125 Tablet 10's
LCD 125 Tablet 10's

LCD 125 Tablet is used in the treatment of Parkinson's disease. It contains Levodopa and Carbidopa, which help to control movement. It may cause common side effects such as nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled/involuntary muscle movement). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CARBIDOPA-25MG+LEVODOPA-100MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About LCD 125 Tablet

LCD 125 Tablet is a prescription medication designed to manage the symptoms of Parkinson's disease and Parkinson-like movement difficulties. It works by restoring the balance of natural chemical messengers in the brain that are responsible for smooth muscle control and coordination. By easing physical symptoms, this medicine helps individuals maintain their daily physical activities and personal independence.

For the best results, you must take LCD 125 Tablet regularly at the exact times prescribed by your doctor. It can be taken with or without food, but taking it at consistent times each day is crucial for keeping your symptoms controlled. Combining this treatment with regular physical activity, a balanced diet, and staying well-hydrated can also significantly improve your daily physical function.

While taking LCD 125 Tablet , some people may experience mild side effects like nausea, dizziness, or dry mouth. However, you should contact your doctor immediately if you experience more serious issues, such as seeing or hearing things that are not there, severe mood changes, or unusual, uncontrollable urges.

Before starting LCD 125 Tablet , you must talk to your doctor if you have a history of heart disease, high or low blood pressure, glaucoma, or mental health conditions. Do not take this medicine if you have untreated narrow-angle glaucoma or if you have taken certain medicines for depression (called MAO inhibitors) within the last 14 days.

LCD 125 Tablet can interact with iron supplements, high-protein foods, and alcohol, which can affect how the medicine is absorbed or increase drowsiness. Special care and close monitoring are required if you are pregnant, breastfeeding, or an elderly individual, as you may be more sensitive to the effects of this medicine. Talk to your doctor or pharmacist if you fall into any of these groups.

Uses of LCD 125 Tablet

LCD 125 Tablet is used to manage the symptoms of Parkinson's disease and Parkinson-like movement difficulties. The detailed uses of LCD 125 Tablet are as follows:

  • Parkinson's disease: LCD 125 Tablet helps manage the primary symptoms of Parkinson's disease, including muscle stiffness, tremors, shaking, and slow or difficult movements.
  • Parkinson-like symptoms: LCD 125 Tablet is used to treat movement difficulties that resemble Parkinson's disease but are caused by other conditions, such as carbon monoxide poisoning or manganese poisoning.
     

Key Benefits

LCD 125 Tablet helps manage movement disorders by improving muscle control and reducing symptoms that interfere with everyday activities. By enhancing mobility and coordination, it supports greater independence and a better quality of life.

  • Helps Reduce Muscle Stiffness and Tremors: By improving the balance of brain chemicals involved in movement, LCD 125 Tablet helps reduce muscle rigidity, tremors, and other movement-related symptoms, making daily activities easier to perform.
  • Supports Better Mobility and Coordination: As movement symptoms improve, LCD 125 Tablet helps enhance balance, coordination, and physical control, reducing the risk of falls and supporting safer, more confident movement.
  • Improves Daily Functioning and Independence: By providing consistent symptom relief, LCD 125 Tablet helps you perform routine tasks such as walking, dressing, writing, and eating with greater comfort, allowing you to maintain a more active and independent lifestyle.
     
Side effects of LCD 125 Tablet
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Eat smaller meals and chew food thoroughly.
  • Try foods with softer textures.
  • If you have difficulty swallowing liquids, use thickener.
  • Learn new swallowing techniques from a speech and language therapist.
  • Avoid alcohol and caffeine as these may dry your throat and mouth making it more difficult to swallow.
  • Consider alternative forms of feeding, such as feeding tubes through nose or a hole into your stomach.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.

Directions for Use

  • LCD 125 Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow LCD 125 Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How LCD 125 Tablet Works

LCD 125 Tablet contains two active components that work together to restore normal muscle movement. The first active component, levodopa, is converted directly into dopamine, a vital chemical messenger in the brain. People with Parkinson's disease have lower levels of dopamine, which leads to movement control issues. By replenishing this brain chemical, the medicine helps restore normal nerve signals to your muscles. The second active component, carbidopa, in LCD 125 Tablet plays a protective role. It prevents the first component from being broken down in the bloodstream before it has a chance to reach the brain. This protective action ensures that more of the active medicine successfully reaches the brain where it is needed, while also reducing common side effects like severe nausea and vomiting in the rest of the body.
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Alcohol

Unsafe

Avoid consumption of alcohol with LCD 125 Tablet as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty concentrating.

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Pregnancy

Caution

LCD 125 Tablet is a Category B pregnancy drug and is given to a pregnant woman only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

LCD 125 Tablet is excreted in human milk, but the effect of LCD 125 Tablet on an infant is unknown. So, LCD 125 Tablet is given to a breastfeeding mother only if the doctor thinks the benefits outweigh the risks.

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Driving

Unsafe

LCD 125 Tablet may cause drowsiness and make you fall asleep suddenly. Therefore, avoid driving if you feel drowsy after taking LCD 125 Tablet .

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Liver

Caution

Take LCD 125 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take LCD 125 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

LCD 125 Tablet is not recommended for children as the safety and efficacy were not established.

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Heart

Consult your doctor

Please consult your doctor before using LCD 125 Tablet if you have pre-existing heart problems. Your doctor will prescribe LCD 125 Tablet if the benefits outweigh the risks.

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Geriatrics

Caution

LCD 125 Tablet can be given safely to the elderly if advised by the doctor.

What if I have taken an overdose of LCD 125 Tablet

In case of an accidental overdose, seek immediate emergency medical attention or contact a nearby centre. Symptoms of an overdose may include severe involuntary muscle spasms, a fast or irregular heartbeat, confusion, or severe dizziness.

Diet & Lifestyle Advise

  • Manage your protein intake: High-protein meals can block your body from properly absorbing this medicine. Try to eat high-protein foods (like meat, fish, dairy, and eggs) at other times of the day, rather than right when you take your dose.
  • Stand up slowly: Since this medicine can cause sudden dizziness when you stand, take your time when rising from a chair or bed to prevent falls.
  • Stay hydrated: Drink plenty of water throughout the day to help manage dry mouth and prevent constipation, which is common in people with Parkinson's disease.
  • Keep a symptom diary: Keep track of when you take your medicine and when your symptoms improve or worsen. Sharing this record helps your doctor fine-tune your treatment plan.
     

Health Queries

Have a query?

How Soon It Starts Working

  • The time required for LCD 125 Tablet to start to work: The time required for LCD 125 Tablet to start to work is 15 minutes after administration.
  • The time for which the effects of LCD 125 Tablet last: The effect of LCD 125 Tablet lasts for 5 to 24 hours.

What if you forget to take LCD 125 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you frequently miss doses.

Storage

•Store LCD 125 Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the container tightly closed to protect the medicine from light, moisture, and extreme heat.

Drug Warnings

  • Do not stop taking this medicine suddenly: Stopping abruptly can cause a dangerous, life-threatening reaction marked by high fever, severe muscle stiffness, and confusion. Always consult your doctor before stopping or reducing your dose.
  • Avoid driving if drowsy: Do not drive, operate machinery, or perform hazardous tasks if you experience sudden sleepiness or extreme dizziness while taking this medicine.
  • Watch for behavioural changes: Tell your family or caregivers to watch for unusual behavioural changes, such as new or increased urges to gamble, spend money, or eat compulsively, and report these to your doctor immediately.
  • Monitor your blood pressure: Check your blood pressure regularly, as this medicine can cause sudden drops in blood pressure when changing positions.
  • Inspect your medication: Check the appearance of your tablets or capsules before taking them. If they appear discoloured, damp, or damaged, consult your pharmacist before use.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Monoamine Oxidase (MAO) Inhibitors: Taking this medicine with certain older depression medications can cause a dangerous, life-threatening spike in blood pressure.
  • Blood Pressure Medications: Combining LCD 125 Tablet with drugs that lower blood pressure may cause your blood pressure to drop too low, resulting in severe dizziness or fainting.
  • Iron Supplements: Multivitamins or supplements containing iron can bind to the medicine in your stomach, reducing the amount your body absorbs.
  • Antipsychotics and Anti-nausea Drugs: Certain medicines used for mental health conditions or severe nausea can block the effects of LCD 125 Tablet , making your movement symptoms worse.
     
Levodopa + CarbidopaMethylene blue
Critical
Levodopa + CarbidopaProcarbazine
Critical

Drug-Drug Interactions

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Levodopa + CarbidopaMethylene blue
Critical
How does the drug interact with LCD 125 Tablet:
Combining levodopa with methylene blue can increase the risk of increased blood pressure.

How to manage the interaction:
Taking Levodopa and Methylene Blue together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs—sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting—make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Levodopa + CarbidopaProcarbazine
Critical
How does the drug interact with LCD 125 Tablet:
Using levodopa together with procarbazine can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Procarbazine with Levodopa together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
Levodopa + CarbidopaTranylcypromine
Critical
How does the drug interact with LCD 125 Tablet:
Taking Tranylcypromine with Levodopa can increase the risk of high blood pressure

How to manage the interaction:
Taking Levodopa with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
Levodopa + CarbidopaPhenelzine
Critical
How does the drug interact with LCD 125 Tablet:
Using levodopa together with phenelzine can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Levodopa with Phenelzine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
Levodopa + CarbidopaIsocarboxazid
Critical
How does the drug interact with LCD 125 Tablet:
Using levodopa together with isocarboxazid can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Isocarboxazid with Levodopa together can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor right away if you experience symptoms like severe headache, confusion, chest pain, or sudden weakness. Do not stop using any medications without a doctor's advice.
Levodopa + CarbidopaFurazolidone
Critical
How does the drug interact with LCD 125 Tablet:
Combining levodopa with furazolidone can increase the risk of increased blood pressure.

How to manage the interaction:
Taking Levodopa and Furazolidone together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs—sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting—make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Levodopa + CarbidopaLinezolid
Critical
How does the drug interact with LCD 125 Tablet:
Using levodopa together with linezolid can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between linezolid and levodopa, you can take these medicines together if prescribed by a doctor. However, if you experience a sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, you should seek immediate medical attention. Do not stop using any medications without talking to a doctor.
Levodopa + CarbidopaSodium oxybate
Severe
How does the drug interact with LCD 125 Tablet:
Using sodium oxybate and levodopa together may increase the risk and severity of side effects

How to manage the interaction:
Taking sodium oxybate and levodopa together can lead to an interaction; it can be taken if your doctor has suggested it. If you experience any symptoms like drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, or slow or shallow breathing, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Levodopa + CarbidopaEsketamine
Severe
How does the drug interact with LCD 125 Tablet:
Coadministration of Levodopa with Esketamine can increase the risk of side effects.

How to manage the interaction:
Although taking Levodopa and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sleepiness, confusion, difficulty concentrating, and impairment in thinking or judgment, consult your doctor immediately. Avoid driving or operating hazardous machinery until the next day, after a restful sleep. Do not stop using any medications without a doctor's advice.
Levodopa + CarbidopaAmisulpride
Severe
How does the drug interact with LCD 125 Tablet:
Coadministration of levodopa with amisulpride may increase the risk and severity of side effects and also reduce the effectiveness of both drugs.

How to manage the interaction:
Although taking amisulpride and levodopa can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience drowsiness, low blood pressure, dizziness, and lightheadedness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • High-Protein Foods: Eating meals rich in protein (such as meat, poultry, fish, eggs, and cheese) at the same time as your dose can severely decrease how much medicine your body absorbs.
  • Alcohol: Drinking alcohol while taking this medicine can worsen side effects like extreme drowsiness, dizziness, and lightheadedness.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPARKINSON AGENTS]

FAQs

LCD 125 Tablet is used in the treatment of Parkinson's disease, with its symptoms including tremors, spasms, muscle stiffness, and poor muscle control.
It is advised to not take LCD 125 Tablet glaucoma (damage of optic nerve that is essential for good vision) as it may increase the fluid pressure inside the eye. However, regular monitoring of pressure in the eyes is recommended while on treatment with LCD 125 Tablet .
LCD 125 Tablet is a combination of two medicines, Levodopa and Carbidopa. Levodopa belongs to the class of medications name as central nervous system agents, while Carbidopa comes in the category of decarboxylase inhibitors. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. While Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream so that more Levodopa can reach to brain.
It is advised not to stop taking LCD 125 Tablet without consulting your doctor as it may lead to a severe condition called withdrawal-emergent hyperpyrexia with symptoms such as confusion, fever, muscle stiffness, changes in heartbeat and breathing. Therefore, take LCD 125 Tablet for as long as your doctor has prescribed it and if you experience any of these symptoms while taking LCD 125 Tablet , please consult your doctor so that the dose may be gradually reduced.
In some cases, prolonged intake of LCD 125 Tablet may lead to a decrease of Vitamin B12 in the body. So, your doctor might recommend regular tests for the Vitamin B12 while using LCD 125 Tablet .
The exact effects of birth control pills with LCD 125 Tablet is still under research. However, it is best to tell your doctor if you are using any type of hormonal contraception. If a person develops diarrhea and vomiting then they need to change their contraception methods like condoms and other contraceptives.
It has been reported that some patients taking LCD 125 Tablet have experienced stomach upset. To avoid such conditions take LCD 125 Tablet should be taken with a meal or snack to avoid or lessen the side effects, including diarrhea, nausea, and indigestion. Later the body becomes habitual to medicine so a person can take it with a light meal or on an empty stomach to get better results. Be sure to ask the doctor about the best time to take the medicine.
Drug interactions have been reported when a person takes Methotrexate with Carbidopa. However, clinical research is still going on to know how does LCD 125 Tablet affects Methotrexate. One should talk to their doctor for more clarification.
Most people do not face any side effects, including jaundice. However, any person who has been taking LCD 125 Tablet for a prolonged time should consult their doctor immediately if they notice yellowing of skin/eyes or abdominal pain.
Patients with narrow-angle glaucoma should avoid intake of LCD 125 Tablet . Levodopa may activate a malignant melanoma (skin cancer), so LCD 125 Tablet should not be used in patients with suspicious, undiagnosed skin lesions or a melanoma history. LCD 125 Tablet also causes a deficiency of vitamin B12, so patient with low vitamin B12 should not take LCD 125 Tablet .
Yes, LCD 125 Tablet can be taken on an empty stomach as it helps maximize its effectiveness. Please consult your doctor if you have concerns regarding it.
Yes, LCD 125 Tablet may cause dark urine. This is harmless and resolves after stopping LCD 125 Tablet . Please consult your doctor if you have concerns regarding it.
The common side effects of LCD 125 Tablet include nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled or involuntary muscle movement). Most of these side effects of LCD 125 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
LCD 125 Tablet may cause sleepiness or drowsiness in some individuals. You are not recommended to drive or operate heavy machinery if you are not alert. Please consult your doctor if it is bothering you.
LCD 125 Tablet should be stored in a cool and dry place away from sunlight and kept away from children’s reach. Dispose of the expired medication through a medication take-back program or by talking to your pharmacist.
Avoid exceeding the recommended dose as it can cause unpleasant side effects. If you're not feeling well or have concerns, talk to your doctor. The doctor will adjust your dose or suggest a better treatment plan for you.
It is highly recommended to avoid alcohol while taking LCD 125 Tablet . Alcohol can increase the risk of side effects like severe drowsiness, lightheadedness, and dizziness. Talk to your doctor if you have concerns about alcohol use.
This is known as the "wearing-off" effect, which can happen as your body adjusts to the medicine. Do not increase your dose or change your schedule on your own. Talk to your doctor, as they may need to adjust your dosing times.
Yes, you can take it with food to reduce nausea, but try to avoid high-protein breakfasts like eggs, meat, or high-protein dairy right around the time of your dose, as protein reduces the medicine's absorption. Talk to your doctor or pharmacist for personalised meal planning advice.
This medicine can cause a temporary drop in blood pressure when you change positions. Standing up slowly from a sitting or lying position can help prevent this. If the dizziness is severe or causes fainting, talk to your doctor immediately.
No, LCD 125 Tablet does not cure Parkinson's disease. Instead, it helps manage and control the physical symptoms, such as shaking, stiffness, and difficulty moving, to improve your daily quality of life. Talk to your doctor about what to expect from your long-term treatment.
Yes, some patients taking this medicine experience intense, uncontrollable urges, such as compulsive gambling, increased sexual urges, binge eating, or compulsive spending. If you or your family notice these changes, talk to your doctor right away.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 017555S069Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Carbidopa And Levodopa Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. National Health Service (NHS). Parkinsons Disease - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Sinemet 12.5 mg/50 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 20 September 2022] Check here
  5. Sinemet 12.5 mg/50 mg Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 20 September 2022] Check here
  6. Merck Sharp & Dohme B.V. Electronic Medicines Compendium (EMC). [Revised in February 2021] [Accessed on 21st May 2025] Check here
  7. CDSCO [Internet]. Cdscoonline.gov.in. 2022 [Accessed on 20 September 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - LCD0001

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