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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lamictal Xr 25Mg Tablet is used to treat epilepsy/seizures/fits. Additionally, it also treats bipolar disorder. It contains Lamotrigine, which reduces the electrical impulses and firing of the nerve impulses that cause fits. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, dry mouth, dizziness, fatigue, abdominal pain, and infection. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

LAMOTRIGINE-0.50MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lamictal Xr 25Mg Tablet

Lamictal Xr 25Mg Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Lamictal Xr 25Mg Tablet also treats bipolar disorder. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. Bipolar disorder is a severe brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioural changes.

Lamictal Xr 25Mg Tablet contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.

You are advised to take Lamictal Xr 25Mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as skin rash, headache, nausea, vomiting, dryness in the mouth, insomnia (difficulty in sleeping), sleepiness, dizziness, back pain, fatigue, abdominal pain, blurred vision, double vision, impaired coordination, nasal congestion (stuffy nose), and infection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, do not stop taking Lamictal Xr 25Mg Tablet without consulting your doctor to avoid worsening of seizures. Do not take Lamictal Xr 25Mg Tablet if you are pregnant or planning for pregnancy unless prescribed by the doctor, as it could lead to serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Lamictal Xr 25Mg Tablet . Consult your doctor before taking Lamictal Xr 25Mg Tablet if you are breastfeeding. Contact your doctor if your child gets her first period whilst on treatment with Lamictal Xr 25Mg Tablet . Do not drive or operate machinery as Lamictal Xr 25Mg Tablet causes drowsiness and dizziness. Avoid consuming alcohol along with Lamictal Xr 25Mg Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies.

Uses of Lamictal Xr 25Mg Tablet

Lamictal Xr 25Mg Tablet is used in the treatment of epilepsy (fits) and bipolar disorder. The detailed uses of Lamictal Xr 25Mg Tablet are as follows:

  • Epilepsy/seizures: Lamictal Xr 25Mg Tablet controls seizures by stabilizing abnormal electrical activity in the brain, reducing their frequency and severity.
  • Bipolar Disorder: Lamictal Xr 25Mg Tablet helps prevent mood swings or depressive episodes, maintaining emotional balance in individuals with bipolar disorder.

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Directions for Use

  • Take Lamictal Xr 25Mg Tablet with food or as directed by your doctor.
  • Always follow your doctor’s advice regarding the prescribed dosage and duration of treatment.
  • Swallow Lamictal Xr 25Mg Tablet whole with a glass of water.
  • Do not crush, chew, or break the tablet.

Medicinal Benefits

  • Lamictal Xr 25Mg Tablet contains Lamotrigine, which helps control seizures by stabilizing abnormal electrical activity in the brain.
  • It reduces the release of glutamate, a chemical messenger that can trigger seizures, preventing excessive nerve overactivity.
  • It decreases the frequency and severity of seizures in conditions such as partial-onset seizures, primary generalized tonic-clonic seizures, and Lennox–Gastaut syndrome.
  • It helps delay the occurrence of mood episodes (depressive, manic, or mixed) in individuals with Bipolar I Disorder, maintaining long-term emotional balance.
  • It has a well-established safety profile in pediatric epilepsy and is not associated with physical or psychological dependence or abuse potential.

How Lamictal Xr 25Mg Tablet Works

Lamictal Xr 25Mg Tablet contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.

Storage

• Store in a cool and dry place away from sunlight.• Keep Lamictal Xr 25Mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Lamictal Xr 25Mg Tablet

Take Lamictal Xr 25Mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include impaired coordination, involuntary eye movement, seizures, decreased level of consciousness, coma, and intraventricular conduction delay (abnormal heart conduction). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Lamictal Xr 25Mg Tablet if you are allergic to Lamotrigine or its ingredients. Seek immediate medical help if you develop sudden swelling of the face, lips, tongue, or throat, difficulty breathing, or severe skin reactions such as rash, blistering, peeling, or sores in the mouth or around the eyes. These reactions may be life-threatening, especially in children, at high starting doses, or when combined with valproic acid.
  • Inform your doctor about all your existing medical conditions, particularly liver, kidney, or pancreas problems, urea cycle disorders, inflammation of the brain and spinal cord lining, porphyria (a blood pigment disorder), or low platelet levels.
  • Tell your doctor about all medicines, supplements, or herbal products you are taking, as certain drugs may interact with Lamictal Xr 25Mg Tablet and increase the risk of side effects.
  • Do not stop taking Lamictal Xr 25Mg Tablet suddenly without your doctor’s advice, as abrupt withdrawal can cause serious, life-threatening seizures.
  • Consult your doctor before using Lamictal Xr 25Mg Tablet if you are pregnant, planning to become pregnant, or breastfeeding. This medicine may harm the unborn baby and could affect the child’s cognitive abilities (reasoning, intelligence, problem-solving) later in life.
  • Use Lamictal Xr 25Mg Tablet with caution in children, as they may have a higher risk of severe skin reactions and other side effects.
  • Avoid alcohol consumption while taking Lamictal Xr 25Mg Tablet , as it can increase dizziness, drowsiness, and the risk of side effects.
  • Do not drive or operate heavy machinery until you know how Lamictal Xr 25Mg Tablet affects you, as it may cause dizziness, drowsiness, or reduced alertness.

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps the body utilise fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Lamictal Xr 25Mg Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

It is advised to avoid alcohol consumption while taking Lamictal Xr 25Mg Tablet . Alcohol intake, along with Lamictal Xr 25Mg Tablet , may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Lamictal Xr 25Mg Tablet is a pregnancy category C drug. Animal studies showed that Lamictal Xr 25Mg Tablet affects the fetus in pregnancy, but there is limited data in humans. Using antipsychotic drugs during the third trimester of pregnancy can cause muscle problems in newborns. Please consult your doctor before taking Lamictal Xr 25Mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Lamictal Xr 25Mg Tablet is excreted into the breast milk. Please consult your doctor before taking Lamictal Xr 25Mg Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Lamictal Xr 25Mg Tablet may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Lamictal Xr 25Mg Tablet can be given to children if prescribed by the doctor. The doctor will adjust the dose.

FAQs

Lamictal Xr 25Mg Tablet is used in the treatment of Epilepsy (fits) and Bipolar disorder. It contains Lamotrigine, which reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Lamictal Xr 25Mg Tablet decreases the brain's excessive and abnormal nerve activity, thereby helping control seizures.

Do not discontinue Lamictal Xr 25Mg Tablet without consulting your doctor. To treat your condition effectively, continue taking Lamictal Xr 25Mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Lamictal Xr 25Mg Tablet . Your doctor will reduce the dose gradually to avoid worsening seizures.

Lamictal Xr 25Mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Dry mouth could be a side-effect of Lamictal Xr 25Mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Lamictal Xr 25Mg Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.

Lamictal Xr 25Mg Tablet contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.

The side effects of Lamictal Xr 25Mg Tablet include sleepiness, dizziness, tremor, back pain, headache, nausea, vomiting, diarrhoea, blurred or double vision, tiredness, fever, dry mouth, sore throat, stuffy nose, stomach pain and infections, including seasonal flu. However, if these side effects persist or worsen, please consult your doctor.

Epilepsy also called as seizure disorder is a brain-related disorder affecting people of all ages characterized by repeated seizures that are brief episodes of involuntary movement that may involve a part of the body or full body. It is caused due to abnormal electrical activity in the brain and sometimes followed by loss of consciousness and control of bladder or bowel function.

Bipolar disorder also called as manic depression is a mental illness that causes unusual shifts in a person's mood, energy, concentration, and activity levels. It is marked by episodes of mood swings ranging from depressive lows to manic highs.

There have been cases where patients were hospitalized after experiencing severe rashes within 8 weeks of starting Lamictal Xr 25Mg Tablet . Sometimes these rashes progress into severe skin infections and may risk the patient’s life. Therefore, if a patient develops rashes after starting Lamictal Xr 25Mg Tablet , it is recommended that Lamictal Xr 25Mg Tablet should be stopped and should not be restarted. The use of Lamictal Xr 25Mg Tablet is stopped even if the rashes are mild and not serious. This is the reason your doctor changed the medicine.

Though it is different from person to person, it may take about 6-8 weeks for your symptoms to improve.

You may experience uncontrollable and quick eye movements, lack of coordination and clumsiness. High doses of Lamictal Xr 25Mg Tablet may cause changes in heartbeat rhythm, balance problems, loss of consciousness, fits (convulsions) or coma. If you suspect you have taken more than the recommended dose of Lamictal Xr 25Mg Tablet , seek medical help immediately, even if there are no signs of discomfort.

You are recommended to consult your doctor before taking Lamictal Xr 25Mg Tablet with other antiepileptic medicines to avoid drug interactions.

Take Lamictal Xr 25Mg Tablet as advised by the doctor. It can be taken with or without food. Swallow it as whole with a glass of water. Do not break, crush or chew it.

Yes, you can take Lamictal Xr 25Mg Tablet if you have symptoms of depression. In fact, Lamictal Xr 25Mg Tablet is used to prevent depression. However, do not self-medicate. Use Lamictal Xr 25Mg Tablet only if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Stiefel India Ltd., 401& 402, A Wing, IV Floor, Floral Deck Plaza, Opp. Rolta Bhavan, Central MIDC Road, Andheri (East), Mumbai – 400093
Other Info - LAM0174

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