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compositionComposition:THIOGUANINE-40MG
prescription
Prescription Medicine
info
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Lanvis 40 Tablet is used to treat blood cancer. It contains Thioguanine which works by preventing the growth of cancer cells and killing them. In some cases, this medicine may cause side effects such as nausea, vomiting, mouth ulcers, loss of appetite, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

THIOGUANINE-40MG

Manufacturer/Marketer :

GlaxoSmithKline Consumer Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lanvis 40 Tablet

Lanvis 40 Tablet is a medication primarily prescribed to treat acute leukemias, which are fast-growing cancers of the white blood cells. It works by targeting and slowing down the production of these abnormal blood cells in the bone marrow. This helps your body recover its normal blood-producing functions.

This medicine is typically taken once daily, and keeping a consistent schedule is very important for it to work effectively. You can take it with or without food, but you must choose one method and stick to it every day. Along with taking this medication, maintaining strict hygiene habits and staying well-hydrated are helpful lifestyle adjustments to protect your body during treatment.

While taking this medicine, some people may experience mild side effects like nausea, vomiting, or a temporary loss of appetite. However, it can also cause serious health issues, such as severe infections or liver damage. If you notice signs of an infection, like a fever, or experience unusual bleeding, you must contact your doctor immediately.

Before you begin taking this medicine, talk to your doctor if you have pre-existing liver conditions, kidney issues, or a genetic condition that affects how you process medications. Do not take this if you are pregnant, planning to become pregnant, or have had a severe allergic reaction to this medication in the past.

Before starting treatment, your doctor may recommend a genetic test called TPMT (thiopurine methyltransferase) testing. This helps determine how well your body can process Lanvis 40 Tablet and allows your doctor to choose a safer starting dose.

This medicine can interact with other treatments, including certain gout medications and other chemotherapy drugs, which can increase the risk of severe side effects. It is also important to avoid alcohol because it can worsen the risk of liver damage. If you are breastfeeding, elderly, or planning any vaccines, talk to your doctor or pharmacist first.

Uses of Lanvis 40 Tablet

Your doctor may prescribe Lanvis 40 Tablet to manage the following conditions:

  • Acute Myeloid Leukemia (AML): Lanvis 40 Tablet helps by stopping the rapid growth and multiplication of abnormal white blood cells in your bone marrow, allowing healthy cells to develop.
  • Acute Lymphoblastic Leukemia (ALL): Lanvis 40 Tablet works to treat this fast-growing blood cancer by interfering with the genetic processes that allow cancer cells to replicate.

Key Benefits

Lanvis 40 Tablet offers significant clinical benefits to help you manage your condition and feel better:

  • Promotes Disease Remission: By targeting and destroying cancer cells, this medication helps bring the leukemia into remission, allowing your body to start recovering.
  • Restores Healthy Blood Cells: By controlling abnormal white blood cells, the medicine helps your bone marrow resume producing healthy red blood cells, normal white blood cells, and platelets.
  • Relieves Severe Symptoms: As your healthy blood levels return to normal, you may experience relief from leukemia symptoms such as chronic fatigue, frequent infections, and easy bruising.
Side effects of Lanvis 40 Tablet
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.

Directions for Use

  • Lanvis 40 Tablet can be taken with or without food at regular intervals, as prescribed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Lanvis 40 Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Lanvis 40 Tablet Works

Lanvis 40 Tablet contains Thioguanine, which belongs to a class of medications known as antimetabolites. These medications are designed to mimic the natural building blocks that your body's cells use to build and repair their genetic material (DNA and RNA). Because leukemia cells divide and grow much faster than normal cells, they rapidly absorb these building blocks. Once the cancer cells take in this medication, the drug integrates into their DNA. This disrupts their ability to copy or repair their genetic structure, preventing the cancer cells from multiplying and ultimately causing them to die.
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Alcohol

Unsafe

Avoid consumption of alcohol with Lanvis 40 Tablet as it may increase the risk of liver damage.

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Pregnancy

Unsafe

Lanvis 40 Tablet is a category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the foetus. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Lanvis 40 Tablet is given to breastfeeding mother only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Lanvis 40 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Lanvis 40 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Lanvis 40 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Lanvis 40 Tablet should be used in children only if advised by a doctor.

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Heart

Caution

Lanvis 40 Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Lanvis 40 Tablet .

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Geriatrics

Caution

Lanvis 40 Tablet should be used with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Lanvis 40 Tablet .

What if I have taken an overdose of Lanvis 40 Tablet

In case of an accidental overdose, seek immediate emergency medical attention. An overdose can cause severe and dangerous drops in your blood cell counts, which require urgent clinical care.

Diet & Lifestyle Advise

  • Practice strict food safety: Avoid eating raw or undercooked foods, such as raw seafood, unpasteurized dairy, or runny eggs, as your immune system is weaker and more vulnerable to foodborne illnesses.
  • Stay well hydrated: Drink plenty of water throughout the day to help support your kidney function and assist your body in clearing out metabolic waste.
  • Avoid crowded places: Stay away from large crowds and individuals who are actively sick to reduce your risk of contracting bacterial or viral infections.
  • Prevent physical injury: Use a soft-bristled toothbrush and an electric razor instead of a manual blade to minimize the risk of cuts and bleeding.
health query

Have a query?

How Soon It Starts Working

The time required for Lanvis 40 Tablet to start to work: The time required for Lanvis 40 Tablet to show its action is unknown. The time for which the effects of Lanvis 40 Tablet last: The duration of action for Lanvis 40 Tablet is clinically unknown.

What if you forget to take Lanvis 40 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one. Talk to your doctor or pharmacist if you are unsure of what to do.

Storage

• Store the tablets at room temperature, ideally between 15°C and 25°C (59°F to 77°F).

Drug Warnings

  • Keep up with regular blood tests: Your doctor will schedule regular complete blood counts (CBCs) and liver function tests (LFTs) to monitor your blood cell levels and liver health. During the early stages of treatment, these tests may be needed weekly so your dose can be adjusted safely.
  • Wear gloves when handling: If a caregiver is preparing or handling your tablets, they should wear protective gloves to avoid directly touching the medicine.
  • Avoid live vaccines: Do not receive any live immunisations (like the MMR vaccine) while taking this medicine, as they can cause severe infections when your immune system is suppressed.
  • Use effective birth control: Both male and female patients must use highly reliable birth control during treatment and for a specified period afterward, as this drug can cause severe harm to an unborn baby.
  • Watch for signs of liver damage: Contact your healthcare provider immediately if you experience yellowing skin, dark urine, or upper stomach pain.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Lanvis 40 Tablet : 

  • Inflammatory bowel disease medications (such as olsalazine, sulfasalazine, or mesalazine): Taking these alongside Lanvis 40 Tablet can significantly increase the risk of severe bone marrow suppression, leading to dangerously low blood cell counts.
  • Other chemotherapy drugs: Combining this medication with other cancer treatments can compound the risk of liver damage and severe blood disorders.
TioguanineBusulfan
Severe

Drug-Drug Interactions

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TioguanineBusulfan
Severe
How does the drug interact with Lanvis 40 Tablet:
Combining Lanvis 40 Tablet with Busulfan can increase the likelihood and seriousness of side effects.

How to manage the interaction:
There may be a possibility of interaction between Lanvis 40 Tablet and Busulfan, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Lanvis 40 Tablet when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Lanvis 40 Tablet contains Thioguanine that works by inhibiting the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Lanvis 40 Tablet stops the multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.
Lanvis 40 Tablet may harm eggs or sperm. Therefore, please consult a doctor before taking Lanvis 40 Tablet if you are planning to become parents.
Tell your doctor before receiving any vaccine while taking Lanvis 40 Tablet . Live vaccines (such as measles, mumps, rubella, polio, or chickenpox vaccines) should generally be avoided because this medicine weakens your immune system and may increase the risk of infection. Your doctor will advise you on which vaccines are safe and when they should be given.
Lanvis 40 Tablet may increase sensitivity to sunlight and cause rash or discolouration of the skin. Therefore, avoid or limit exposure to the sun for a long time. Wear protective clothing and use sunscreen before going out in the sun.
Yes. Lanvis 40 Tablet can lower your body's ability to fight infections by reducing your white blood cell count. Signs of infection include fever, chills, sore throat, cough, mouth sores, or urinary symptoms. A fever while taking Lanvis 40 Tablet is a medical emergency and should be reported to your doctor immediately, as it may indicate a serious infection requiring prompt treatment. Avoid close contact with people who have contagious illnesses whenever possible.
No, you must not crush, break, or chew the tablets. Because this is a potent chemotherapy medication, touching or inhaling the dust from broken tablets can be harmful to you or anyone handling them. Talk to your doctor or pharmacist if you cannot swallow the tablets whole.
You must contact your doctor immediately. A fever is a medical emergency when your immune system is suppressed by this medication, as it often indicates a serious infection that requires rapid treatment. Talk to your doctor.
It is highly recommended to avoid alcohol while taking this medicine. Both alcohol and this medication can place significant stress on your liver, and combining them increases your risk of liver damage. Talk to your doctor.
No, this medication should not be taken during pregnancy because it can cause severe harm or birth defects to an unborn baby. You must use effective birth control while using this medication. Talk to your doctor.
Regular blood tests are critical to monitor your liver function and measure your blood cell counts. This allows your doctor to make sure the medicine is working safely and to adjust your dose if your levels drop too low. Talk to your doctor.
You must avoid live vaccines while taking this medication, as your weakened immune system cannot safely process them. Always consult with your healthcare provider before receiving any vaccine. Talk to your doctor.
Key warning signs include yellowing of your skin or eyes, dark-colored urine, pain in the upper right side of your stomach, or sudden swelling in your belly. Contact your medical team immediately if you notice these. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

24-25 Floor, One Horizon Center Golf Course Road, Dlf Phase 5 Gurgaon 122002, India
Other Info - LAN0164
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