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  3. Lapmed 250 Tablet 30's

Lapmed 250 Tablet 30's, Pack of 1
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lapmed 250 Tablet 30's is an anti-cancer medicine used in the treatment of Breast cancer. It contains Lapatinib, which works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells; this causes inhibition of the cancer cell growth and, finally, initiation of apoptosis. It is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

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Composition :

LAPATINIB-250Mg

Manufacturer/Marketer :

Medion Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lapmed 250 Tablet 30's

Lapmed 250 Tablet 30's is an anti-cancer medicine used in the treatment of Breast cancer. The abnormal growth of cancer (malignant) cells in the breast is known as breast cancer. Lapmed 250 Tablet 30's is used in combination with capecitabine for treating patients with HER2-positive advanced or metastatic breast cancer who have received prior treatment, including anthracycline, taxane, and trastuzumab. This medicine is also used in combination with letrozole for the treatment of hormone receptor-positive metastatic breast cancer in patients with HER2-positive (human epidermal growth factor receptor 2) for whom hormonal therapy is indicated.

Lapmed 250 Tablet 30's contains Lapatinib as an active ingredient which belongs to the class of kinase inhibitors. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Lapmed 250 Tablet 30's may cause certain side effects such as diarrhea, fatigue, nausea, rash, indigestion, loss of appetite, headache, vomiting, weakness, mouth sores, hair loss, dry skin, myalgia, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Lapmed 250 Tablet 30's should be taken as advised by your doctor. Take the medicine around the same time daily. Do not skip any dose; if you forget any dose, try to take it as soon as you remember unless it is time for your next dose. Do not double the dose.

Lapmed 250 Tablet 30's should be avoided if you are allergic to it or any other components of this medicine. Before starting the treatment, let your doctor know about your complete medical history and medication history, including vitamin and herbal supplements. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease before taking Lapmed 250 Tablet 30's. Lapmed 250 Tablet 30's is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand. 

Uses of Lapmed 250 Tablet 30's

Lapmed 250 Tablet 30's is used in the treatment of Breast Cancer. The detailed use of Lapmed 250 Tablet 30's is as follows:

  • Treatment of breast cancer: Lapmed 250 Tablet 30's is used to treat advanced or metastatic HER2-Positive Breast Cancer.

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Directions for Use

  • Lapmed 250 Tablet 30's can be taken 1 hour before a meal or 2 hours after a meal.
  • It is advised to take Lapmed 250 Tablet 30's once daily or as advised by your doctor.
  • Swallow the medicine as a whole with a glass of water.
  • Do not break, chew or crush Lapmed 250 Tablet 30's.

Medicinal Benefits

Lapmed 250 Tablet 30's contains Lapatinib as an active ingredient, which is used in combination with capecitabine for treating patients with HER2-positive advanced or metastatic breast cancer who have received prior treatment. This medicine works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

How Lapmed 250 Tablet 30's Works

Lapmed 250 Tablet 30's contains Lapatinib as an active ingredient which belongs to the class of kinase inhibitors. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Lapmed 250 Tablet 30's out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Lapmed 250 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

What if I have taken an overdose of Lapmed 250 Tablet 30's

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Lapmed 250 Tablet 30's may include severe diarrhea/vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Lapmed 250 Tablet 30's should be avoided if you are allergic to it or any other components of this medicine. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease, as it can cause adverse effects. Lapmed 250 Tablet 30's may cause left ventricular ejection fraction, prolonged QT interval, hepatotoxicity, interstitial lung disease, pneumonitis, severe diarrhoea, and hypersensitivity reactions during the treatment. Hence, careful observation should be performed for any reactions in the patient. If any changes or hypersensitivity reactions occur, treatment should be discontinued. Lapmed 250 Tablet 30's is known to cause embryo-fetal toxicity. Hence, if you are pregnant or planning to become pregnant, inform your doctor beforehand. Breastfeeding should be discontinued in nursing mothers during the treatment. Lapmed 250 Tablet 30's should be given to children only if prescribed by the paediatrician. Lapmed 250 Tablet 30's is not recommended for use in children as the safety and efficacy are not established. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Drug-Drug Interactions

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LapatinibClarithromycin
Severe
LapatinibColchicine
Severe

Drug-Drug Interactions

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LapatinibClarithromycin
Severe
How does the drug interact with Lapmed 250 Tablet:
Taking clarithromycin with Lapmed 250 Tablet may increase the blood levels of Lapmed 250 Tablet. This might make you more likely to develop side effects such as diarrhea, liver damage, and heart problems.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Lapmed 250 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats during treatment with Lapmed 250 Tablet. Do not stop using any medications without a doctor's advice.
LapatinibColchicine
Severe
How does the drug interact with Lapmed 250 Tablet:
Coadministration of colchicine with Lapmed 250 Tablet results in increased colchicine levels in the blood, increasing the risk of serious side effects

How to manage the interaction:
Although taking Colchicine and Lapmed 250 Tablet together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, if you experience abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.
LapatinibFosphenytoin
Severe
How does the drug interact with Lapmed 250 Tablet:
When Lapmed 250 Tablet is taken with Fosphenytoin, it can cause the body to process Lapmed 250 Tablet faster. This can lead to low treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Fosphenytoin and Lapmed 250 Tablet, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
LapatinibSotalol
Severe
How does the drug interact with Lapmed 250 Tablet:
Taking Sotalol and Lapmed 250 Tablet can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Lapmed 250 Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
LapatinibGatifloxacin
Severe
How does the drug interact with Lapmed 250 Tablet:
Taking Gatifloxacin and Lapmed 250 Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Lapmed 250 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LapatinibPosaconazole
Severe
How does the drug interact with Lapmed 250 Tablet:
Taking Lapmed 250 Tablet with posaconazole can increase the levels of Lapmed 250 Tablet in the blood, which can lead to an increased risk of side effects such as diarrhea, liver problems, and heart problems.

How to manage the interaction:
Although using Posaconazole and Lapmed 250 Tablet together can result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.
LapatinibPazopanib
Severe
How does the drug interact with Lapmed 250 Tablet:
Taking Pazopanib with Lapmed 250 Tablet may significantly increase the blood levels of pazopanib. This can make you more likely to develop serious side effects such as liver problems, irregular heart rhythm, bleeding and high blood pressure,

How to manage the interaction:
Taking Pazopanib with Lapmed 250 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, chest pain or tightness, pain in your arms, back, neck, or jaw, shortness of breath, numbness or weakness on one side of your body, and difficulty speaking. Do not stop using any medications without a doctor's advice.
LapatinibAmiodarone
Severe
How does the drug interact with Lapmed 250 Tablet:
Coadministration of Amiodarone together with Lapmed 250 Tablet may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Lapmed 250 Tablet interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
LapatinibCeritinib
Severe
How does the drug interact with Lapmed 250 Tablet:
Taking Lapmed 250 Tablet with ceritinib may significantly increase the blood levels of Lapmed 250 Tablet. This can make you more likely to develop side effects such as diarrhea and liver problems.

How to manage the interaction:
Co-administration of Ceritinib with Lapmed 250 Tablet can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LapatinibLoperamide
Severe
How does the drug interact with Lapmed 250 Tablet:
When taken in combination Lapmed 250 Tablet may significantly raise the loperamide levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking loperamide with Lapmed 250 Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC
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Alcohol

Unsafe

Alcohol intake might increase the risk of worsening your condition. Hence, avoid alcohol consumption till your condition improves.

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Pregnancy

Unsafe

Lapmed 250 Tablet 30's is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Lapmed 250 Tablet 30's. Use reliable methods of birth control while on treatment with Lapmed 250 Tablet 30's.

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Breast Feeding

Unsafe

Avoid nursing your child while on treatment with Lapmed 250 Tablet 30's as it can cause serious side effects to the newborn baby.

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Driving

Consult your doctor

It is unknown whether Lapmed 250 Tablet 30's will affect your mental ability to drive or operate machines. Hence, consult your doctor for information regarding this.

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Liver

Caution

Inform your doctor if you have any pre-existing liver disease. Your doctor may adjust the dose of the medicine based on the condition. Lapmed 250 Tablet 30's is known to cause hepatotoxicity in some patients. If you notice any reactions such as itching, yellowing of the skin or eyes, dark urine, abdominal pain, unusual bleeding, or pale or dark stools, discontinue the treatment and inform your doctor immediately.

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Kidney

Caution

Limited data are available on the effect of Lapmed 250 Tablet 30's in kidney-impaired patients. Hence, if you have a pre-existing or a history of kidney disease, inform your doctor.

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Children

Unsafe

Lapmed 250 Tablet 30's is not recommended for use in children as the safety and efficacy are not established.

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Heart

Lapmed 250 Tablet 30's may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Lapmed 250 Tablet 30's.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Lapmed 250 Tablet 30's to geriatric patients. Your doctor will prescribe Lapmed 250 Tablet 30's if the benefits outweigh the risks.

FAQs

Lapmed 250 Tablet 30's is used to treat breast cancer.

Lapmed 250 Tablet 30's contains Lapatinib, which works by inhibiting the excess production of a protein called human epidermal growth factor receptor 2 (HER2) in mammalian cells. This causes inhibition of the cancer cell growth.

Inform your doctor whether you have received any other breast cancer treatment. Lapmed 250 Tablet 30's may cause left ventricular ejection fraction, hypersensitivity reactions, hepatotoxicity, severe diarrhea, and embryo-fetal toxicity during the treatment. Hence, inform your oncologist if you have any cardiovascular conditions, liver/kidney disease, are pregnant, are planning to become pregnant, or are breastfeeding before taking Lapmed 250 Tablet 30's.

Hepatotoxicity (liver toxicity) has been reported in clinical studies and postmarketing experience with Lapmed 250 Tablet 30's. Hepatotoxicity can be fatal, and deaths have been reported. The cause of death is unknown. If you have upper stomach pain, itching, dark urine, clay-coloured faeces, or jaundice (yellowing of the skin or eyes), inform your doctor immediately.

Lapmed 250 Tablet 30's may cause side effects such as diarrhoea, fatigue, nausea, rash, indigestion, loss of appetite, headache, vomiting, weakness, mouth sores, hair loss, dry skin, myalgia, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Lapmed 250 Tablet 30's is an anti-cancer medicine used in the treatment of breast cancer.

Yes, Lapmed 250 Tablet 30's can be given in combination with other anti-cancer drugs if prescribed by the doctor. Talk to the doctor if you have any concerns.

Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine. It should be taken one hour before or at least one hour after food.

Drink enough fluids and eat fibre-rich food if you experience diarrhoea. Consult the doctor if the diarrhoea persists or worsens.

Use sunscreen, soap-free cleanser and products that are free from fragrance and are hypoallergenic. Get your skin checked regularly by the doctor during treatment with Lapmed 250 Tablet 30's.

Before starting Lapmed 250 Tablet 30's, the doctor may advise heart and liver function tests.

Consult the doctor if you are planning for pregnancy after treatment with Lapmed 250 Tablet 30's. Use effective contraception during treatment with Lapmed 250 Tablet 30's and for a week after the last dose.

Country of origin

India

Manufacturer/Marketer address

409, 4Th Floor, Devika Tower, Chander Nagar, Surya Nagar, Ghaziabad-201011, Uttar Pradesh, India
Other Info - LAP0071

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:51 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/022059s023lbl.pdf
  2. https://medlineplus.gov/druginfo/meds/a607055.html
  3. https://reference.medscape.com/drug/tykerb-lapatinib-342235
  4. https://www.mayoclinic.org/drugs-supplements/lapatinib-oral-route/side-effects/drg-20070910?p=1
  5. https://www.drugs.com/mtm/lapatinib.html
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