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compositionComposition:DIETHYLCARBAMAZINE-150MG+LEVOCETIRIZINE-2.5MG
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Prescription Medicine
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Ledec 150mg/2.5mg Tablet is used to treat certain parasitic infections such as Bancroft's filariasis, Eosinophilic lung, Loiasis, and River blindness. It contains levocetirizine (antihistamine) and Diethylcarbamazine (anthelmintic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from allergic symptoms. Diethylcarbamazine is an anthelmintic (anti-parasitic) that works by causing paralysis of the worms by reducing muscular activity.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DIETHYLCARBAMAZINE-150MG+LEVOCETIRIZINE-2.5MG

Manufacturer/Marketer :

Trans Life Sciences

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Ledec 150mg/2.5mg Tablet

Ledec 150mg/2.5mg Tablet is an oral prescription medication used to treat certain parasitic infections, including lymphatic filariasis and tropical pulmonary eosinophilia. It combines two active mechanisms to clear parasitic worms from the body while simultaneously relieving the allergic reactions often triggered by these infections. By addressing both the infection and the immune response, this medication helps manage symptoms effectively.

For the best results, you must take Ledec 150mg/2.5mg Tablet consistently at the exact times prescribed by your health professional. You can take this medicine with or without food, though taking it with a meal can help prevent potential stomach discomfort. Making simple lifestyle adjustments, such as drinking plenty of fluids and resting, can support your body's recovery process during treatment.

While taking Ledec 150mg/2.5mg Tablet, some people may experience mild side effects, which typically resolve as your body adjusts to the medication. Common experiences include sleepiness, a dry mouth, or mild headaches. However, if you experience severe symptoms like a high fever, intense joint pain, or signs of a serious allergic reaction, you should consult your doctor immediately.

Do not take this if you have severe kidney disease or a known allergy to any of the ingredients in this medicine. It is highly important to talk to your doctor before starting Ledec 150mg/2.5mg Tablet if you have a history of liver damage, moderate kidney problems, or seizure disorders, as your treatment plan may need to be adjusted.

This medication can interact with other substances, so you should tell your healthcare team about all other medicines you are currently taking. Avoid drinking alcohol while using Ledec 150mg/2.5mg Tablet, as it can significantly increase drowsiness and put unnecessary strain on your liver. Additionally, if you are pregnant, planning a pregnancy, or breastfeeding, consult your doctor before beginning treatment, as diethylcarbamazine is generally avoided during pregnancy unless clearly needed. Older adults and people with kidney problems may require closer monitoring or dose adjustment because the medicine may remain in the body longer.

Uses of Ledec 150mg/2.5mg Tablet

This medicine is used to treat certain parasitic infections and relieve the allergic symptoms associated with them. The detailed uses of this medicine are as follows:

  • Lymphatic filariasis: Ledec 150mg/2.5mg Tablet helps eliminate microfilariae (young parasitic worms) and adult worms in the lymphatic system, helping prevent swelling and damage to the lymph vessels and surrounding tissues.
  • Tropical pulmonary eosinophilia (TPE): Helps treat this parasitic lung condition associated with an increased number of allergy-fighting white blood cells (eosinophils), reducing symptoms such as cough, wheezing, and breathing difficulty.
  • Allergic symptoms associated with parasitic infections: Helps relieve itching, hives, skin rashes, and other allergic symptoms that may occur when parasites release substances or die during treatment.

Key Benefits

Ledec 150mg/2.5mg Tablet helps treat parasitic infections while relieving the allergic symptoms associated with them. Its benefits include:

  • Helps eliminate the parasites responsible for infections such as lymphatic filariasis and tropical pulmonary eosinophilia (a lung condition caused by the body's reaction to tiny parasitic worms).
  • Relieves allergic symptoms, including itching, hives, skin rashes, and respiratory discomfort, that may occur during the infection or as parasites are destroyed.
  • Helps reduce coughing, wheezing, and breathing difficulties associated with parasitic lung involvement.
  • Lowers the risk of long-term complications, such as chronic lymphatic damage, persistent swelling (lymphedema), and elephantiasis, by treating the underlying infection promptly.
  • Improves overall comfort, supports faster recovery, and helps you return to your normal daily activities when used as prescribed.
Side effects of Ledec 150mg/2.5mg Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Take Ledec 150mg/2.5mg Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Ledec 150mg/2.5mg Tablet Works

Ledec 150mg/2.5mg Tablet contains Levocetirizine and Diethylcarbamazine. Levocetirizine: It is a second-generation antihistamine that blocks the action of histamine, a natural chemical released during allergic reactions. It helps relieve symptoms such as itching, hives, skin rashes, swelling, and other allergic manifestations that may occur during parasitic infections or while the parasites are being eliminated. Diethylcarbamazine: It is an antiparasitic medicine that acts against both the larval (microfilariae—tiny larval worms) and, in some cases, adult stages of filarial parasites. It weakens the parasites so that your body's immune system can destroy them more easily, helping clear the infection.
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Alcohol

Caution

Avoid consumption of alcohol with Ledec 150mg/2.5mg Tablet as it may increase adverse effects.

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Pregnancy

Caution

Ledec 150mg/2.5mg Tablet should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Ledec 150mg/2.5mg Tablet.

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Breast Feeding

Caution

Caution should be exercised. Ledec 150mg/2.5mg Tablet should not be used in nursing mothers unless clearly necessary. So, inform the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the medication to the mother.

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Driving

Caution

Ledec 150mg/2.5mg Tablet may cause drowsiness or dizziness in some people. Therefore, drive only if you are alert after taking Ledec 150mg/2.5mg Tablet.

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Liver

Caution

It should be used with caution if you have liver problems. Inform your doctor before receiving Ledec 150mg/2.5mg Tablet if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

It should be used with caution if you have kidney problems. Inform your doctor before receiving Ledec 150mg/2.5mg Tablet if you have a history of kidney diseases. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Ledec 150mg/2.5mg Tablet is not recommended for children under six years old as safety and effectiveness were not established. However, for children above six years, Ledec 150mg/2.5mg Tablet should be used with caution if prescribed by a doctor.

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Heart

Caution

Please consult your doctor before taking Ledec 150mg/2.5mg Tablet if you have pre-existing heart problems.

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Geriatrics

Caution

Elderly patients may require caution and dose adjustments, as Ledec 150mg/2.5mg Tablet may increase the risk of side effects.

What if I have taken an overdose of Ledec 150mg/2.5mg Tablet

If you or someone else takes more than the prescribed dose of Ledec 150mg/2.5mg Tablet, seek immediate medical attention or contact your local emergency services. Symptoms of an overdose may include extreme drowsiness, severe dizziness, or intense nausea.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water and other clear fluids throughout the day to help your body eliminate waste products released as the parasites are cleared.
  • Eat light, nutritious meals: Choose simple, freshly prepared, and easily digestible foods to reduce stress on your digestive system during treatment.
  • Get adequate rest: Prioritize rest and avoid strenuous physical activities to support your immune system and help your body recover from the infection.
  • Prevent mosquito bites: If you live in or travel to areas where filariasis is common, use mosquito nets, wear protective clothing, and apply insect repellent to help prevent reinfection.
health query

Have a query?

How Soon It Starts Working

The time required for Ledec 150mg/2.5mg Tablet to start to work: Ledec 150mg/2.5mg Tablet ideally shows its action within 20 minutes to 1 hour after administration. The time for which the effects of Ledec 150mg/2.5mg Tablet last: The duration of action for Ledec 150mg/2.5mg Tablet is clinically unknown.

What if you forget to take Ledec 150mg/2.5mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Ledec 150mg/2.5mg Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F), in a cool, dry place.

Drug Warnings

  • Avoid activities requiring alertness: Do not drive, operate heavy machinery, or perform tasks requiring full mental alertness after taking Ledec 150mg/2.5mg Tablet, as it may cause drowsiness.
  • Monitor for treatment-related reactions: Watch for signs of a Mazzotti-like reaction, such as fever, rash, joint pain, swollen lymph nodes, or worsening itching, which may occur as parasites die. Contact your doctor if these symptoms are severe or persistent.
  • Inspect the medicine before use: Check the packaging and tablets before taking the medicine. Do not use the tablets if the blister pack is damaged or if the tablets appear discolored, cracked, or otherwise abnormal.
  • Inform healthcare providers: Tell your doctor, dentist, or any other healthcare professional that you are taking Ledec 150mg/2.5mg Tablet before undergoing any medical, dental, or surgical procedures.

Drug-Drug Interactions

verifiedApollotooltip
  • Central Nervous System Depressants: Taking this medicine with anxiety medications, sleeping pills, muscle relaxants, or other antihistamines may increase the risk of extreme drowsiness and dizziness.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid consuming alcohol while taking this medicine, as it can severely worsen sleepiness, impair coordination, and increase the risk of liver damage.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIHELMINTICS]

FAQs

Ledec 150mg/2.5mg Tablet is used to treat Parasitic infections (Bancroft’s filariasis, Eosinophilic lung, Loiasis, and River blindness).
Ledec 150mg/2.5mg Tablet is a combination of two medications: levocetirizine and diethylcarbamazine. Levocetirizine is an antihistamine (anti-allergic medication) that acts by preventing the activity of histamine, a chemical that causes allergic reactions. It aids in the alleviation of allergy symptoms. Diethylcarbamazine is an anthelmintic (anti-parasitic) that causes worm paralysis by lowering muscle activity.
No, Ledec 150mg/2.5mg Tablet is not used to treat tapeworm or pinworm infections. However, please consult a doctor if you have a tapeworm or pinworm infection so that appropriate medicine may be prescribed.
Ledec 150mg/2.5mg Tablet may cause vision problems such as night blindness, tunnel vision or loss of vision if used for prolonged time. Therefore, regular eye check-ups are recommended while taking Ledec 150mg/2.5mg Tablet.
You are not recommended to stop taking Ledec 150mg/2.5mg Tablet without consulting your doctor, as it may worsen the infection or cause recurring symptoms. Therefore, take Ledec 150mg/2.5mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Ledec 150mg/2.5mg Tablet, please consult your doctor.
Yes, the use of Ledec 150mg/2.5mg Tablet may cause drowsiness. If you experience drowsiness, avoid driving and operating machinery.
Yes, Ledec 150mg/2.5mg Tablet is effective in treating certain parasitic infections such as eosinophilic lung, loiasis, Bancroft's filariasis and river blindness if taken in the dose and duration prescribed by the doctor.
Do not take Ledec 150mg/2.5mg Tablet if you are allergic to any of its ingredients. Consult the doctor before using Ledec 150mg/2.5mg Tablet if you are pregnant or breastfeeding.
Ledec 150mg/2.5mg Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
If you forget a dose of Ledec 150mg/2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed one and take the scheduled dose. Do not double the dose.
Yes, Ledec 150mg/2.5mg Tablet is safe if taken in the dose and duration prescribed by the doctor.
It is generally not recommended to take this medication during pregnancy unless your doctor determines that the benefits outweigh the risks. Diethylcarbamazine is usually avoided during pregnancy unless clearly necessary. Talk to your doctor to understand the potential risks and available treatment options.
No, you should avoid alcohol while on this medication. Alcohol can significantly increase drowsiness, cause dizziness, and increase the risk of liver damage. Talk to your doctor or pharmacist if you have questions.
Mild itching can occur as the parasites are cleared from your body. However, if you develop a severe, worsening rash, hives, swelling, or trouble breathing, seek emergency medical care immediately. Talk to your doctor to determine the next steps.
This medicine should only be given to children if it has been specifically prescribed by a pediatrician, as the dosage depends heavily on the child's age and weight. Talk to your doctor to ensure safe use.
Yes, you can take it with or without food. However, if you experience stomach upset or nausea, taking it with a meal can help soothe your stomach. Talk to your doctor or pharmacist for personalized advice.
This medicine is highly effective at killing the active parasites causing the infection, which prevents further damage. However, it may not completely reverse chronic, long-term swelling that has already occurred over years. Talk to your doctor about comprehensive management options for chronic symptoms.

Disclaimer

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Country of origin

India
Other Info - LE91885
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