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compositionComposition:VANCOMYCIN-500MG
prescriptionPrescription Medicine
Ledovanc 500 Injection 1's
Ledovanc 500 Injection is an antibiotic used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), and osteomyelitis (infection of the bone). It contains Vancomycin, which prevents the formation of bacterial protective covering (cell wall) needed for their survival. Thus, it kills bacteria.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VANCOMYCIN-500MG

Manufacturer/Marketer :

Genetics Lifescience Healthcare Business

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

Ledovanc 500 Injection belongs to a class of antibiotics called glycopeptide, primarily used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), and osteomyelitis (infection of the bone). Bacterial infection occurs when harmful bacteria grow in the body and causes illness.

Ledovanc 500 Injection is composed of 'Vancomycin'. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall), which is needed for them to survive.

Ledovanc 500 Injection will be administered by a healthcare professional; do not self-administer it. Common side effects of Ledovanc 500 Injection are application site reactions like pain, redness, and swelling. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Let your doctor know if you have liver/kidney diseases, hearing problems, and stomach/intestinal disorders before starting Ledovanc 500 Injection. Do not use Ledovanc 500 Injection while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Ledovanc 500 Injection may affect vaccines' activity. Pregnant and breastfeeding women should consult the doctor before starting Ledovanc 500 Injection. Avoid alcohol consumption to prevent any undesired effects while using Ledovanc 500 Injection. Ledovanc 500 Injection should be used for children only when prescribed by a doctor, depending on the child's age and body weight.

Uses of Ledovanc 500 Injection

Ledovanc 500 Injection is used in the treatment of severe bacterial infections, especially when other antibiotics are contraindicated or ineffective, or when the bacteria are resistant to standard antibiotics. The detailed uses of Ledovanc 500 Injection are as follows:

  • Bloodstream infections: Ledovanc 500 Injection is used in hospitalized patients to treat bacterial septicemia (sepsis), helping to eliminate infections from the bloodstream.
  • Infective Endocarditis: Ledovanc 500 Injection is effective in treating infective endocarditis (infection of the heart lining and valves), especially when caused by methicillin-resistant Staphylococcus aureus (MRSA) .
  • Lower Respiratory Tract Infections: Ledovanc 500 Injection is commonly used to treat pneumonia (lung infection) acquired during hospital stays, particularly in patients at high risk of MRSA infection.
  • Bone and Joint Infections: Ledovanc 500 Injection is also prescribed for infections of the bone (osteomyelitis) and joints (septic arthritis) caused by susceptible bacteria.
  • Skin and Soft Tissue Infections: Ledovanc 500 Injection is effective in managing bacterial infections of the skin and underlying tissues, such as infected wounds, abscesses, and cellulitis.
  • Intra-abdominal Infections: Ledovanc 500 Injection is used to treat infections within the abdominal cavity, such as peritonitis and abdominal abscesses.
  • Bacterial Meningitis: Ledovanc 500 Injection is administered in combination with other antibiotics to treat meningitis (infection of the brain and spinal cord), particularly when caused by resistant Streptococcus pneumoniae.
  • Prophylaxis in Surgical Procedure Ledovanc 500 Injection may be given prophylactically before heart or joint surgeries, especially in patients at high risk of MRSA infection or those allergic to beta-lactam antibiotics.

Key Benefits

Ledovanc 500 Injection is composed of 'Vancomycin'. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) needed to survive. Ledovanc 500 Injection used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), osteomyelitis (infection of the bone), endocarditis (infection of the inner lining of the heart ), skin and soft tissue infection, surgical prophylaxis (infections during surgery) and lower respiratory tract infections.

Side effects of Ledovanc 500 Injection
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Directions for Use

  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Ledovanc 500 Injection will be administered by a healthcare professional.
  • Do not self-administer.
Ledovanc 500 Injection is composed of 'Vancomycin'. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall), which is needed for them to survive.
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Alcohol

Caution

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

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Pregnancy

Caution

Please consult your doctor before taking Ledovanc 500 Injection if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Ledovanc 500 Injection can be excreted into breast milk when used by a nursing mother. Please consult your doctor before taking Ledovanc 500 Injection if you are breastfeeding.

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Driving

Caution

There is limited data on how Ledovanc 500 Injection affects your driving ability. Please seek medical advice for more information.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Ledovanc 500 Injection. However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have any history of kidney problems. Your doctor will weigh the benefits and potential risks before prescribing Ledovanc 500 Injection. However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Ledovanc 500 Injection should be used for children only when prescribed by a doctor, depending on the child's age and body weight.

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Heart

Consult your doctor

Limited information is available; please consult your doctor.

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Geriatrics

Caution

Ledovanc 500 Injection can be administered in elderly patients with extreme caution, if prescribed by the physician.

The overdose of Ledovanc 500 Injection is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Ledovanc 500 Injection, please inform your doctor immediately.

Diet & Lifestyle Advise

  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. 
  • Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it can make you dehydrated and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Have a query?

Drug Warnings

Let your doctor know if you are allergic reactions to any medicines. Some rare cases may cause serious side effects like hearing problems (such as ringing in the ears, and hearing loss) and signs of kidney problems (such as a change in the amount of urine), please stop using the medicine in such cases and consult your doctor immediately. Do not use Ledovanc 500 Injection while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Ledovanc 500 Injection may affect vaccines' activity. Pregnant and breastfeeding women should consult their doctor before taking Ledovanc 500 Injection. Avoid alcohol consumption to prevent any undesired effects while using Ledovanc 500 Injection. Ledovanc 500 Injection should be used for children only when prescribed by a doctor, depending on the child's age and body weight.

Drug-Drug Interactions

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VancomycinCidofovir
Critical
VancomycinIodamide
Severe

Drug-Drug Interactions

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VancomycinCidofovir
Critical
How does the drug interact with Ledovanc 500 Injection:
Coadministration of Ledovanc 500 Injection with Cidofovir can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Ledovanc 500 Injection with Cidofovir is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you develop signs such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
VancomycinIodamide
Severe
How does the drug interact with Ledovanc 500 Injection:
Coadministration of Ledovanc 500 Injection with Iodamide can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Ledovanc 500 Injection with Iodamide may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinIohexol
Severe
How does the drug interact with Ledovanc 500 Injection:
Coadministration of Ledovanc 500 Injection with Iohexol can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Ledovanc 500 Injection with Iohexol may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinBCG vaccine
Severe
How does the drug interact with Ledovanc 500 Injection:
Taking Ledovanc 500 Injection with the BCG vaccine can decrease the effects of the BCG vaccine.

How to manage the interaction:
Although there is a possible interaction between Valsartan and the BCG vaccine, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
VancomycinMetrizamide
Severe
How does the drug interact with Ledovanc 500 Injection:
Taking Ledovanc 500 Injection with Metrizamide can increase the risk of kidney damage.

How to manage the interaction:
Although taking Ledovanc 500 Injection together with Metrizamide may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinIoversol
Severe
How does the drug interact with Ledovanc 500 Injection:
Taking Ledovanc 500 Injection with Ioversol can increase the risk of kidney damage.

How to manage the interaction:
Although taking Ledovanc 500 Injection together with Ioversol may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythms. Do not discontinue any medication without consulting a doctor.
VancomycinSirolimus
Severe
How does the drug interact with Ledovanc 500 Injection:
Coadministration of Ledovanc 500 Injection with Sirolimus can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Ledovanc 500 Injection with Sirolimus may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinHuman immunoglobulin
Severe
How does the drug interact with Ledovanc 500 Injection:
Coadministration of Ledovanc 500 Injection with Human immunoglobulin can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Ledovanc 500 Injection with Human immunoglobulin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
VancomycinIopamidol
Severe
How does the drug interact with Ledovanc 500 Injection:
Taking Ledovanc 500 Injection with Iopamidol can increase the risk of kidney damage.

How to manage the interaction:
Although taking Ledovanc 500 Injection together with Iopamidol may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
VancomycinTenofovir alafenamide
Severe
How does the drug interact with Ledovanc 500 Injection:
Coadministration of Ledovanc 500 Injection with Tenofovir alafenamide can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Ledovanc 500 Injection with Tenofovir alafenamide may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Ledovanc 500 Injection is used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), and osteomyelitis (infection of the bone).

Ledovanc 500 Injection contains Vancomycin which kills bacteria by preventing them from forming the bacterial protective covering (cell wall), which is needed for them to survive.

Ledovanc 500 Injection can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Ledovanc 500 Injection if you are undergoing any vaccinations.

Diarrhoea can be a side-effect of Ledovanc 500 Injection. Clostridium difficile-associated diarrhoea (CDAD) is also reported during the usage of antibiotics like Ledovanc 500 Injection. Therefore, when the patient has diarrhoea, undergoing an examination is advised to rule out the chances of CDAD following Ledovanc 500 Injection therapy.

While using Ledovanc 500 Injection, caution should be exercised for patients with a history of kidney impairment, hearing problems, newborns, and the elderly population.

Yes, Ledovanc 500 Injection is an antibiotic. It contains vancomycin as its active ingredient, which belongs to the class of medications called glycopeptide antibiotics.

The dose of Ledovanc 500 Injection varies depending on the severity of the infection and the patient's condition. However, your doctor will determine the exact dose and duration based on your specific condition. Do not self-administer.

Ledovanc 500 Injection typically starts working soon after intravenous infusion. However, it may take a few days to notice significant improvement in symptoms. It's important to complete the full course of treatment as prescribed by your doctor.

The common side effects of Ledovanc 500 Injection are pain, redness, and swelling at the injection site. If any of these side effects persist or worsen, please consult your doctor.

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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