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Composition :

LENALIDOMIDE-10MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lenangio 10 Capsule

Lenangio 10 Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenangio 10 Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
 
Lenangio 10 Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenangio 10 Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Lenangio 10 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Lenangio 10 Capsule if you are pregnant or breastfeeding. Lenangio 10 Capsule may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Lenangio 10 Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Lenangio 10 Capsule must use effective contraception. Inform your doctor regarding your health condition and medications before taking Lenangio 10 Capsule to rule out any interactions.

Uses of Lenangio 10 Capsule

Treatment of Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Lenangio 10 Capsule as a whole with water; do not crush or chew it.

Key Benefits

Lenangio 10 Capsule belongs to the group of medicines called immunomodulatory agents. Lenangio 10 Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenangio 10 Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenangio 10 Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Lenangio 10 Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

How Lenangio 10 Capsule Works

Lenangio 10 Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenangio 10 Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Lenangio 10 Capsule
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Lenangio 10 Capsule

Take Lenangio 10 Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Lenangio 10 Capsule if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Lenangio 10 Capsule if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Lenangio 10 Capsule if you are breastfeeding as it is not unknown if it passes into breastmilk. Lenangio 10 Capsule may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Lenangio 10 Capsule is not recommended for use in children. Avoid consuming alcohol along with Lenangio 10 Capsule as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

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LenalidomideRotavirus vaccine
Critical
LenalidomideAnakinra
Critical

Drug-Drug Interactions

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LenalidomideRotavirus vaccine
Critical
How does the drug interact with Lenangio 10 Capsule:
Administering the Rotavirus vaccine together with Lenangio 10 Capsule may increase the risk of infections.

How to manage the interaction:
Taking Lenangio 10 Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Lenangio 10 Capsule. Do not stop using any medications without consulting a doctor.
LenalidomideAnakinra
Critical
How does the drug interact with Lenangio 10 Capsule:
Taking anakinra with Lenangio 10 Capsule can increase the risk of negative side effects.

How to manage the interaction:
Taking Lenangio 10 Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Lenangio 10 Capsule:
When combining the Yellow fever vaccine with Lenangio 10 Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenangio 10 Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Lenangio 10 Capsule:
Combining the BCG vaccine with Lenangio 10 Capsule increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenangio 10 Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Lenangio 10 Capsule:
Combining Lenangio 10 Capsule with Leflunomide can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Lenangio 10 Capsule and Leflunomide together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, contact your doctor right away. These symptoms include infection, liver problems, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lenangio 10 Capsule:
Coadministration of Lenangio 10 Capsule with Testosterone can increase levels of testosterone in the blood.

How to manage the interaction:
Coadministration of Testosterone with Lenangio 10 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lenangio 10 Capsule:
Taking Infliximab with Lenangio 10 Capsule can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although taking Lenangio 10 Capsule and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lenangio 10 Capsule:
Co-administration of rosuvastatin with Lenangio 10 Capsule may increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is an interaction between Lenangio 10 Capsule and rosuvastatin, it can be taken if prescribed by a doctor. However, if you experience muscle pain, tenderness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideDiethylstilbestrol
Severe
How does the drug interact with Lenangio 10 Capsule:
Taking Lenangio 10 Capsule together with diethylstilbestrol may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Lenangio 10 Capsule and diethylstilbestrol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomidePravastatin
Severe
How does the drug interact with Lenangio 10 Capsule:
Pravastatin combined with Lenangio 10 Capsule may raise the risk of rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is a possible interaction between Lenangio 10 Capsule and Pravastatin, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - like pain, weakness, fever, or dark-colored urine - it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Lenangio 10 Capsule as it might cause increased dizziness.

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Pregnancy

Unsafe

Lenangio 10 Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Lenangio 10 Capsule as it is unknown if Lenangio 10 Capsule passes into breastmilk.

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Driving

Unsafe

Lenangio 10 Capsule may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Lenangio 10 Capsule is not recommended for children below 18years as the safety and effectiveness have not been established.

Have a query?

FAQs

Lenangio 10 Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It is also used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Lenangio 10 Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.

Do not stop taking Lenangio 10 Capsule on your own. You are advised to take Lenangio 10 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lenangio 10 Capsule .

No, it is not safe to father a child while taking Lenangio 10 Capsule . Lenangio 10 Capsule can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Lenangio 10 Capsule and for at least 4weeks after discontinuing Lenangio 10 Capsule , even if you have undergone a successful vasectomy. Male patients taking Lenangio 10 Capsule must not donate semen whilst taking Lenangio 10 Capsule and for 4weeks after discontinuing Lenangio 10 Capsule .

Patients taking Lenangio 10 Capsule must not donate blood during the treatment with Lenangio 10 Capsule and for 1month after discontinuation of Lenangio 10 Capsule as the donated blood might be given to pregnant women whose foetus should not be exposed to Lenangio 10 Capsule since it causes severe birth defects.

People with multiple myeloma taking Lenangio 10 Capsule may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Lenangio 10 Capsule for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.

Lenangio 10 Capsule might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Lenangio 10 Capsule .

You should take Lenangio 10 Capsule at the same time every day. You can take the capsules with or without food.

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

Some people treated with Lenangio 10 Capsule may rarely get other cancers. Consult your doctor for more details.

Yes, you will need to get regular blood tests while taking Lenangio 10 Capsule . Your doctor may suggest taking tests before and during treatment.

Yes, even women with fertility difficulties must take birth control while taking this medication. You must also take a negative pregnancy test 10 to 14 days before treatment and again 24 hours before. You will be tested for pregnancy every 2 to 4 weeks while on Lenangio 10 Capsule .

Lenangio 10 Capsule contains Lenalidomide as an active ingredient.

Common side effects of Lenangio 10 Capsule may include fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you persistently experience any of these side effects.

Lenangio 10 Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

Avoid breastfeeding while taking Lenangio 10 Capsule as it is unknown if Lenangio 10 Capsule passes into breastmilk.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - LEN0010

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