Myelosafe Capsule 10's
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About Myelosafe Capsule
Myelosafe Capsule is a medicine primarily prescribed to treat certain types of blood cancers and bone marrow disorders, such as multiple myeloma and myelodysplastic syndromes. It works by targeting abnormal cells in the bone marrow and helping the body regulate its immune response. This medication is crucial in stopping the progression of these serious conditions.
This medicine is typically taken once daily on a very specific schedule set by your doctor, and it must be taken consistently at the same time each day to be effective. You can take the capsules with or without food, but you should swallow them whole with a glass of water. Making lifestyle adjustments, such as drinking plenty of fluids and eating balanced meals, can support your body during this treatment.
While taking Myelosafe Capsule , you may experience common side effects such as fatigue, mild diarrhoea, or dry skin. However, you must contact your doctor immediately if you notice serious symptoms like sudden shortness of breath, severe leg swelling, high fever, or unusual bruising. Your healthcare provider will monitor your blood counts closely to manage these risks safely.
Before starting this medication, talk to your doctor if you have kidney disease, liver damage, or a history of blood clots. Do not take this if you are pregnant or planning to become pregnant, as it can cause severe, life-threatening birth defects. Both male and female patients must strictly adhere to specific pregnancy prevention programs while on this therapy.
It is important to discuss all other medicines, alcohol use, and smoking habits with your provider, as they can increase your risk of blood clots or alter how the medication works. Pregnant and breastfeeding women must completely avoid this medicine, while elderly individuals should consult their doctor for personalised dose monitoring due to natural changes in kidney function.
Uses of Myelosafe Capsule
Your doctor may prescribe Myelosafe Capsule to help manage the following conditions:
- Multiple myeloma: Myelosafe Capsule helps by slowing the growth of cancerous plasma cells in the bone marrow and boosting the immune system's ability to destroy them.
- Myelodysplastic syndromes (MDS): Myelosafe Capsule helps patients with specific genetic blood disorders by improving red blood cell production and reducing the need for frequent blood transfusions.
- Mantle cell lymphoma: Myelosafe Capsule helps treat this fast-growing type of white blood cell cancer by stopping the multiplication of cancer cells when other therapies have not worked.
- Follicular and marginal zone lymphoma: Myelosafe Capsule works in combination with other therapies to target and control the growth of abnormal white blood cells in the lymphatic system.
Key Benefits
Myelosafe Capsule is used to treat certain blood cancers and bone marrow disorders. It works by slowing the growth of abnormal cells, supporting the immune system, and helping improve blood cell production in appropriate patients.
- Helps Control Disease Progression: Slows the growth and spread of abnormal cells, helping manage certain blood cancers and bone marrow disorders.
- Supports Healthy Blood Cell Production: May improve the production of healthy red blood cells in eligible patients, reducing the need for blood transfusions.
- Strengthens the Immune Response: Helps the immune system recognise and fight abnormal cells more effectively.
- Reduces Symptoms of Blood Disorders: By improving blood cell counts, it may help reduce fatigue, weakness, and other symptoms associated with anaemia and bone marrow disorders.
- Supports Long-Term Disease Management: Regular treatment as prescribed may help prolong disease control, improve treatment outcomes, and enhance quality of life.
- Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
- Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
- Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
- Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
- If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
- In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
- Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
- If you experience severe bleeding or bruising, seek emergency medical attention immediately.
- Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
- Get sufficient sleep and manage stress which helps in improving white blood cell count.
- Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
- Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
- Report the itching to your doctor immediately; they may need to change your medication or dosage.
- Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
- Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
- Try not to scratch, as this can worsen the itching and irritate your skin.
- If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
- Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
- Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
- Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
- Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
- Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
- Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
- Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Directions for Use
- Myelosafe Capsule can be taken with or without food.
- It is usually taken once daily or as prescribed by your doctor.
- Swallow Myelosafe Capsule as a whole with a glass of water.
- Do not crush, chew, or open it.
How Myelosafe Capsule Works
Alcohol
Unsafe
You are recommended to avoid alcohol consumption while taking Myelosafe Capsule as it might cause increased dizziness.
Pregnancy
Unsafe
Myelosafe Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or are planning a pregnancy.
Breast Feeding
Unsafe
Avoid breastfeeding while taking Myelosafe Capsule as it is unknown if Myelosafe Capsule passes into breastmilk.
Driving
Unsafe
Myelosafe Capsule may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.
Liver
Consult your doctor
Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Consult your doctor
Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Unsafe
Myelosafe Capsule is not recommended for children below 18 years as the safety and effectiveness have not been established.
Heart
Caution
Myelosafe Capsule should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Myelosafe Capsule .
Geriatrics
Caution
Myelosafe Capsule should be given with caution in elderly patients due to an increased risk of side effects. Dose adjustment may be required based on their health condition.
What if I have taken an overdose of Myelosafe Capsule
Diet & Lifestyle Advise
- Stay well hydrated: Drink plenty of water throughout the day to support your kidney function and help your body process and clear the medication efficiently.
- Practice infection prevention: Wash your hands frequently and avoid raw or undercooked meats, eggs, and unwashed produce, as your immune system may be weaker during treatment.
- Incorporate gentle exercise: Engage in low-impact physical activities, such as daily walks, to help manage fatigue and reduce the risk of developing blood clots. Always consult your healthcare provider before starting any new exercise routine.
- Moisturise your skin: Apply a thick, alcohol-free moisturiser daily to manage dry or itchy skin and prevent cracking, which can lead to infections.

Have a query?
How Soon It Starts Working
- The time required for Myelosafe Capsule to start to work: The time required for Myelosafe Capsule to show its action is unknown.
- The time for which the effects of Myelosafe Capsule last: The duration of action for Myelosafe Capsule is clinically unknown.
What if you forget to take Myelosafe Capsule
Storage
Drug Warnings
- Do not donate blood: You must not donate blood during your treatment and for at least 4 weeks after your final dose to prevent the drug from reaching pregnant women.
- Avoid handling broken capsules: If a capsule is broken or leaking, do not touch the powder. If skin contact occurs, wash the area immediately with soap and water to prevent accidental absorption.
- Follow strict birth control guidelines: Both men and women must use reliable forms of birth control exactly as outlined by your doctor, as this medicine causes severe birth defects.
- Use a soft toothbrush: Your blood's clotting ability may be reduced during treatment, so use a soft-bristled toothbrush and a gentle electric razor to prevent bleeding gums or cuts.
- Attend all scheduled blood tests: Your doctor will require regular blood monitoring to check your blood cell counts and kidney function. Never skip these appointments.
Drug-Drug Interactions
Drug-Drug Interaction Summary:
Myelosafe Capsule may interact with certain medicines, affecting its effectiveness or increasing the risk of side effects.
- Digoxin: Taking Myelosafe Capsule alongside digoxin can increase the levels of digoxin in your blood, which may require your doctor to monitor your heart medication more closely.
- Blood thinners: Using blood-thinning medications or medicines that alter clotting can increase your risk of severe bleeding or blood clots.
- Immune-suppressing medicines: Combining Myelosafe Capsule with other therapies that lower your body's immune response can significantly increase your risk of developing serious infections.
Drug-Drug Interactions
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Combining the BCG vaccine with Myelosafe Capsule increases the risk of vaccine-related infections or a diminished vaccine response.
How to manage the interaction:
Taking Myelosafe Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
When combining the Yellow fever vaccine with Myelosafe Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.
How to manage the interaction:
Taking Myelosafe Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
Administering the Rotavirus vaccine together with Myelosafe Capsule may increase the risk of infections.
How to manage the interaction:
Taking Myelosafe Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Myelosafe Capsule. Do not stop using any medications without consulting a doctor.
Taking anakinra with Myelosafe Capsule can increase the risk of negative side effects.
How to manage the interaction:
Taking Myelosafe Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Taking Darbepoetin alfa with Myelosafe Capsule can increase the risk of blood clots.
How to manage the interaction:
Although there is an interaction between Myelosafe Capsule and darbepoetin alfa, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of Myelosafe Capsule with Clozapine can increase the risk of neutropenia (low white blood cells count).
How to manage the interaction:
Although there is an interaction between Myelosafe Capsule and clozapine, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when urinating. Do not stop using any medications without talking to a doctor.
Using Atezolizumab and Myelosafe Capsule can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between Atezolizumab and Myelosafe Capsule, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Taking Myelosafe Capsule together with dienestrol may increase the risk of dangerous blood clots.
How to manage the interaction:
Although there is an interaction between Myelosafe Capsule and dienestrol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Myelosafe Capsule and conestat alfa may increase the risk of blood clots.
How to manage the interaction:
Although there is an interaction between Myelosafe Capsule and conestat alfa, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Estradiol and Myelosafe Capsule can increase the risk of blood clots.
How to manage the interaction:
Although there is an interaction between Myelosafe Capsule and estradiol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Reference
- Electronic Medicines Compendium (EMC). Pil.347 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
- U.S. Food and Drug Administration (FDA). 021880S034Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
- Drugs.com Clinical Review Team. Lenalidomide Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
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- Lenalidomide Lenalidomide. [Accessed on 26 Mar. 2019]Check here
- LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. 2012. [Accessed on 08 Jul. 2023]Check here
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