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compositionComposition:LENALIDOMIDE-10MG
prescription
Prescription Medicine
info
Myelosafe Capsule 10's

Myelosafe Capsule is used to treat cancers such as multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It contains lenalidomide, which works by stimulating the immune system to attack the cancer cells. It also kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. In some cases, this medicine may cause side effects, such as fatigue, constipation, diarrhoea, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LENALIDOMIDE-10MG

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Myelosafe Capsule

Myelosafe Capsule is used to treat multiple myeloma, myelodysplastic syndromes, deletion 5q MDS, mantle cell lymphoma, and follicular lymphoma. Multiple myeloma is a cancer of plasma cells that causes abnormal antibody production and bone damage.

Myelosafe Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer.

In some cases, you may experience certain common side effects, such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.

Inform your doctor if you are allergic to Myelosafe Capsule or any of its components. Avoid taking Myelosafe Capsule if you are pregnant or breastfeeding. Myelosafe Capsule may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Men and women taking Myelosafe Capsule must use effective contraception.

Uses of Myelosafe Capsule

Myelosafe Capsule is used in the treatment of certain types of blood cancers and related disorders. The detailed uses of Myelosafe Capsule include:

  • Treatment of multiple myeloma: Myelosafe Capsule is used in combination with other medicines to treat patients with multiple myeloma, a cancer of plasma cells.
  • Management of myelodysplastic syndromes (MDS): Myelosafe Capsule is effective in treating certain types of MDS, a group of disorders caused by poorly formed or dysfunctional blood cells.
  • Treatment of mantle cell lymphoma: Myelosafe Capsule is used to manage mantle cell lymphoma, a rare and aggressive type of non-Hodgkin’s lymphoma.
  • Treatment of follicular lymphoma: Myelosafe Capsule may be used in adults with follicular lymphoma, a slow-growing type of non-Hodgkin’s lymphoma, especially after prior treatment failure.

Key Benefits

  • Myelosafe Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.
  • Myelosafe Capsule works by helping the body’s immune system and directly attacks cancer. 
  • This medicine stops the development of cancer cells, prevents the growth of blood vessels in cancer, and stimulates the part of the immune system that attacks cancer cells.
  • Myelosafe Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
  • Myelosafe Capsule is used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
Side effects of Myelosafe Capsule
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • Myelosafe Capsule can be taken with or without food.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Myelosafe Capsule as a whole with a glass of water.
  • Do not crush, chew, or open it.

How Myelosafe Capsule Works

Myelosafe Capsule contains lenalidomide, which works by helping the body's immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels from growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Myelosafe Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Myelosafe Capsule as it might cause increased dizziness.

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Pregnancy

Unsafe

Myelosafe Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or are planning a pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Myelosafe Capsule as it is unknown if Myelosafe Capsule passes into breastmilk.

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Driving

Unsafe

Myelosafe Capsule may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Myelosafe Capsule is not recommended for children below 18 years as the safety and effectiveness have not been established.

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Heart

Caution

Myelosafe Capsule should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Myelosafe Capsule .

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Geriatrics

Caution

Myelosafe Capsule should be given with caution in elderly patients due to an increased risk of side effects. Dose adjustment may be required based on their health condition.

What if I have taken an overdose of Myelosafe Capsule

Take Myelosafe Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause serious side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.
  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears.

Have a query?

How Soon It Starts Working

  • The time required for Myelosafe Capsule to start to work: The time required for Myelosafe Capsule to show its action is unknown. 
  • The time for which the effects of Myelosafe Capsule last: The duration of action for Myelosafe Capsule is clinically unknown.

What if you forget to take Myelosafe Capsule

If you miss a dose of Myelosafe Capsule , take it within the next 12 hours. If it has been more than 12 hours, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Myelosafe Capsule out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Myelosafe Capsule if you are allergic to any of its components.
  • Inform your doctor if you have/had blood clots, a heart attack, neuropathy, a slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, a viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems.
  • Do not take Myelosafe Capsule if you are pregnant, as it might cause severe birth defects or the death of the unborn baby.
  • Avoid taking Myelosafe Capsule if you are breastfeeding, as it is unknown if it passes into breastmilk.
  • Myelosafe Capsule may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Myelosafe Capsule is not recommended for use in children.
  • Avoid consuming alcohol along with Myelosafe Capsule as it could lead to increased dizziness and sleepiness.
  • Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Myelosafe Capsule may interact with digitalis glycosides (digoxin), blood thinner (warfarin), and hormone (erythropoietin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have anaemia, blood clots, infections, heart, kidney, or liver problems.

LenalidomideBCG vaccine
Critical
LenalidomideRotavirus vaccine
Critical

Drug-Drug Interactions

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LenalidomideBCG vaccine
Critical
How does the drug interact with Myelosafe Capsule:
Combining the BCG vaccine with Myelosafe Capsule increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Myelosafe Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideRotavirus vaccine
Critical
How does the drug interact with Myelosafe Capsule:
Administering the Rotavirus vaccine together with Myelosafe Capsule may increase the risk of infections.

How to manage the interaction:
Taking Myelosafe Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Myelosafe Capsule. Do not stop using any medications without consulting a doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Myelosafe Capsule:
When combining the Yellow fever vaccine with Myelosafe Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Myelosafe Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideAnakinra
Critical
How does the drug interact with Myelosafe Capsule:
Taking anakinra with Myelosafe Capsule can increase the risk of negative side effects.

How to manage the interaction:
Taking Myelosafe Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideEltrombopag
Severe
How does the drug interact with Myelosafe Capsule:
Coadministration of eltrombopag with Myelosafe Capsule can increase the risk or severity of blood clots.

How to manage the interaction:
Although there is an interaction between Myelosafe Capsule and eltrombopag, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomidePembrolizumab
Severe
How does the drug interact with Myelosafe Capsule:
Using Myelosafe Capsule and pembrolizumab together can increase the risk of adverse effects.

How to manage the interaction:
Taking Myelosafe Capsule with Pembrolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
LenalidomideDiethylstilbestrol
Severe
How does the drug interact with Myelosafe Capsule:
Taking Myelosafe Capsule together with diethylstilbestrol may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Myelosafe Capsule and diethylstilbestrol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideVoclosporin
Severe
How does the drug interact with Myelosafe Capsule:
Combining voclosporin with Myelosafe Capsule can raise the chances of developing severe infections and specific types of cancer, such as skin cancer and lymphoma.

How to manage the interaction:
Although taking Myelosafe Capsule and Voclosporin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Contact your doctor immediately if you notice any signs of infection like fever, chills, sore throat, or muscle aches. Other symptoms to watch out for include diarrhea, shortness of breath, weight loss, or pain while urinating. Do not stop using any medications without a doctor's advice.
LenalidomideNatalizumab
Severe
How does the drug interact with Myelosafe Capsule:
Combining Myelosafe Capsule with Natalizumab can increase the chances of experiencing harmful side effects.

How to manage the interaction:
Although there is a possible interaction between Myelosafe Capsule and Natalizumab, you can take these medicines together if prescribed by your doctor. If you experience symptoms like infection, neurological problems, fever, diarrhea, or confusion, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
LenalidomideTamoxifen
Severe
How does the drug interact with Myelosafe Capsule:
Taking Myelosafe Capsule together with tamoxifen may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Myelosafe Capsule and tamoxifen, it can be taken if prescribed by a doctor. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[IMMUNOMODULATORS]

FAQs

Myelosafe Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It is also used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
Myelosafe Capsule works by helping the body immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.
Do not stop taking Myelosafe Capsule on your own. You are advised to take Myelosafe Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Myelosafe Capsule .
No, it is not safe to father a child while taking Myelosafe Capsule . Myelosafe Capsule can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Myelosafe Capsule and for at least 4weeks after discontinuing Myelosafe Capsule , even if you have undergone a successful vasectomy. Male patients taking Myelosafe Capsule must not donate semen whilst taking Myelosafe Capsule and for 4weeks after discontinuing Myelosafe Capsule .
Patients taking Myelosafe Capsule must not donate blood during the treatment with Myelosafe Capsule and for 1month after discontinuation of Myelosafe Capsule as the donated blood might be given to pregnant women whose foetus should not be exposed to Myelosafe Capsule since it causes severe birth defects.
People with multiple myeloma taking Myelosafe Capsule may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Myelosafe Capsule for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.
Myelosafe Capsule might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Myelosafe Capsule .
You should take Myelosafe Capsule at the same time every day. You can take the capsules with or without food.
Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Some people treated with Myelosafe Capsule may rarely get other cancers. Consult your doctor for more details.
Yes, you will need to get regular blood tests while taking Myelosafe Capsule . Your doctor may suggest taking tests before and during treatment.
Yes, even women with fertility difficulties must take birth control while taking this medication. You must also take a negative pregnancy test 10 to 14 days before treatment and again 24 hours before. You will be tested for pregnancy every 2 to 4 weeks while on Myelosafe Capsule .
Myelosafe Capsule contains Lenalidomide as an active ingredient.
Common side effects of Myelosafe Capsule may include fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you persistently experience any of these side effects.
Myelosafe Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
Avoid breastfeeding while taking Myelosafe Capsule as it is unknown if Myelosafe Capsule passes into breastmilk.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.347 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. U.S. Food and Drug Administration (FDA). 021880S034Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Lenalidomide Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. MedlinePlus. A608001 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  5. Lenalidomide Lenalidomide. [Accessed on 26 Mar. 2019] Check here
  6. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. 2012. [Accessed on 08 Jul. 2023] Check here
  7. Lenalidomide [Prescribing Information]. 2022. [Accessed on 08 Jul. 2023]Check here

Country of origin

INDIA

Manufacturer/Marketer address

NO.21, V CROSS,VENKATESA NAGAR EAST, PONDICHERRY 605008 605008 PY 605008 IN , -
Other Info - MYE0011

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