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Lesuwin Injection is used to treat digestive conditions such as dyspepsia, GERD, IBS, nausea, and vomiting, as well as certain mental health conditions. It works by improving gut movement and blocking dopamine activity in the brain. Common side effects include abdominal pain, drowsiness, constipation, weight gain, tiredness, and weakness.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Win Health Pharma

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Lesuwin Injection

Lesuwin Injection is a prescription medicine primarily injected to treat severe digestive problems, such as persistent indigestion, bloating, and diabetic gastroparesis. It is also used to manage severe nausea and vomiting when oral medications cannot be tolerated. This medicine helps normalize the movement of the stomach and intestines to restore comfortable digestion.

Because this medicine is given as an injection, it is typically administered at specific times determined by a healthcare provider to ensure consistent relief. For the best results, it is helpful to make simple dietary changes alongside your medical treatment. Eating smaller, more frequent meals and avoiding heavily spiced foods can support your recovery.

While taking Lesuwin Injection, some patients may experience mild side effects like drowsiness or changes in their menstrual cycles. However, you must contact your doctor immediately if you notice serious symptoms, such as severe muscle stiffness, tremors, or an irregular heartbeat. Your safety depends on recognizing these signs early.

Do not take this medicine if you have a history of epilepsy, manic episodes, or bleeding and blockages in your stomach or intestines. It is vital to share your complete medical history with your doctor before starting treatment. This is especially true if you have a history of heart issues or breast cancer.

This medication can interact with other substances, such as sleeping pills or alcohol, which may significantly increase drowsiness. Always consult your doctor or pharmacist if you are pregnant, breastfeeding, or planning a pregnancy before receiving this injection.

Uses of Lesuwin Injection

Your doctor may prescribe Lesuwin Injection to help manage the following conditions:

  • Severe Indigestion (Dyspepsia): Lesuwin Injection helps reduce persistent upper abdominal pain, bloating, and early fullness by speeding up the movement of food through the stomach.
  • Diabetic Gastroparesis: This medicine relieves delayed stomach emptying in patients with diabetes, reducing symptoms like nausea, vomiting, and abdominal discomfort.
  • Severe Nausea and Vomiting: It acts on the gut and brain signals to effectively prevent and control the urge to vomit.
  • Gastroesophageal Reflux Disease (GERD): By improving the tone of the lower esophageal sphincter, it prevents stomach acid from flowing back up into the food pipe.

Key Benefits

When used as directed as part of your treatment plan, Lesuwin Injection may provide the following benefits:

  • Helps relieve severe nausea and vomiting: Helps reduce nausea and vomiting, especially when oral medicines cannot be taken.
  • Supports stomach emptying: Helps food move more easily from the stomach into the intestines, reducing symptoms caused by delayed stomach emptying.
  • May relieve digestive discomfort: Helps reduce symptoms such as bloating, upper abdominal discomfort, early fullness after meals, and indigestion.
  • May help reduce acid reflux symptoms: Helps reduce the backflow of stomach contents into the food pipe, relieving symptoms such as heartburn and acid regurgitation.
  • Supports improved comfort during eating: As digestive symptoms improve, eating and drinking may become more comfortable, helping you maintain your normal daily activities.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Lesuwin Injection will be administered by the doctor.
  • Do not self-administer.

How Lesuwin Injection Works

Lesuwin Injection contains levosulpiride, a prokinetic medicine (a medicine that helps improve the movement of food through the digestive tract) and a dopamine D2 receptor blocker (a medicine that blocks the action of dopamine, a natural chemical messenger in the body). It blocks dopamine D2 receptors (proteins that respond to dopamine) in the digestive tract. This increases the release of acetylcholine (a natural chemical messenger that stimulates muscle movement), helping the muscles of the stomach and intestines contract more effectively. As a result, food moves through the digestive system more easily, and the stomach empties faster. Levosulpiride also blocks dopamine receptors in the vomiting centre (the area of the brain that helps control nausea and vomiting). This helps reduce nausea and vomiting.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Lesuwin Injection to prevent unpleasant side effects.

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Pregnancy

Unsafe

Avoid taking Lesuwin Injection if you are pregnant. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Lesuwin Injection. Consult your doctor if you have any concerns.

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Driving

Caution

Lesuwin Injection may cause drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Consult your doctor before taking Lesuwin Injection if you have a liver impairment or liver problems.

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Kidney

Caution

Consult your doctor before taking Lesuwin Injection if you have kidney impairment or kidney problems.

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Children

Caution

Limited information is available regarding the usage of Lesuwin Injection in children. Please consult a doctor.

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Heart

Caution

Lesuwin Injection should be used with caution in heart patients, as it can alter heart rate and may trigger irregular rhythms. Always consult your doctor to assess risks and determine if it's appropriate for your condition.

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Geriatrics

Caution

Lesuwin Injection can be used in geriatric patients, but older adults may be more sensitive to side effects like dizziness, drowsiness, or heart rhythm changes. It's best administered under medical supervision with appropriate dose adjustments.

What if I have taken an overdose of Lesuwin Injection

If you receive too much of this medicine, you may experience severe drowsiness, tremors, or muscle stiffness. Seek immediate medical attention or visit the nearest emergency room right away.

Diet & Lifestyle Advise

  • Eat smaller meals: Eat smaller, more frequent meals instead of large meals to help reduce bloating and improve stomach emptying.
  • Stay upright after eating: Avoid lying down for at least 2 to 3 hours after meals to help reduce acid reflux and heartburn.
  • Choose foods carefully: Limit fatty, fried, spicy, or very rich foods if they worsen your digestive symptoms.
  • Stay well hydrated: Drink enough water throughout the day to support healthy digestion.
  • Avoid smoking and limit trigger drinks: Avoid smoking and limit alcohol, caffeinated drinks, and carbonated beverages if they make your symptoms worse.
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How Soon It Starts Working

  • The time required for Lesuwin Injection to start to work: The time required for Lesuwin Injection to show its action is unknown.
  • The time for which the effects of Lesuwin Injection last: The effect of Lesuwin Injection lasts for 12 hours.

What if you forget to take Lesuwin Injection

Since this injection is usually given by a healthcare professional, a missed dose is unlikely. If you are managing your injections at home and miss a scheduled time, contact your doctor or pharmacist for guidance. Do not inject a double dose to make up for a forgotten one.

Storage

•Store Lesuwin Injection injections at a controlled room temperature, typically between 15°C and 30°C. •Do not freeze the medicine, and keep it away from direct sunlight, heat, and moisture.

Drug Warnings

  • Avoid driving until you know how you feel: This medicine may cause drowsiness, dizziness, or blurred vision. Do not drive, cycle, or operate machinery until you know how it affects you.
  • Avoid alcohol: Do not drink alcohol during treatment, as it can increase drowsiness and dizziness.
  • Watch for unusual movements: Consult your doctor right away if you develop muscle stiffness, shaking, uncontrollable movements of your face, tongue, or body, restlessness, or difficulty moving.
  • Report hormone-related changes: Consult your doctor right away if you notice breast swelling, breast discharge, missed or irregular periods, or changes in sexual desire or sexual function.
  • Tell your doctor about heart problems: Before receiving this medicine, tell your doctor if you have a history of heart disease, an irregular heartbeat, or have been told you have low potassium or magnesium levels.
  • Tell your doctor about other medicines: Inform your doctor about all medicines you are taking, especially medicines that cause drowsiness or medicines used to treat heart rhythm problems or mental health conditions.
  • Seek urgent medical help for severe symptoms: Consult your doctor right away if you develop a high fever, severe muscle stiffness, confusion, heavy sweating, or a fast or irregular heartbeat.
  • Attend follow-up appointments: Keep all scheduled appointments so your doctor can check how well the treatment is working and whether any changes to your treatment are needed.

Drug-Drug Interactions

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  • Medicines that cause drowsiness: Combining Lesuwin Injection with sleeping pills, strong pain relievers, or allergy medicines may significantly increase sleepiness and slow down reaction times.
  • Anticholinergic drugs: Medications used to treat muscle spasms or parkinsonism may reduce the gut-stimulating effects of Lesuwin Injection.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol: Avoid drinking alcohol while receiving this medication, as it can dangerously increase drowsiness and dizziness.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS, GASTROPROKINETIC AGENTS]

FAQs

Lesuwin Injection is used to treat gastrointestinal problems such as dyspepsia (indigestion), diabetic gastroparesis (delayed stomach emptying caused by diabetes-related nerve damage), gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), nausea, and vomiting when oral therapy is not advisable/feasible. Additionally, it may also be used to treat schizophrenia, psychosis, depression, anxiety, and Tourette's syndrome (repeated, uncontrollable movements or sounds).
Lesuwin Injection contains Levosulpiride, which enhances the contractions in the gut and improves stomach emptying. This improves food movement through the gut, thereby treating disorders related to the stomach and intestines. Additionally, Lesuwin Injection works by blocking dopamine activity in the brain, thereby improving mood, behaviour, and thoughts in psychotic disorders.
Lesuwin Injection may cause weight gain. Maintain a proper weight by eating healthy food and regular exercise. Consult your doctor if you have any concerns.
Constipation could be a side effect of Lesuwin Injection. However, it is not necessary for everyone taking Lesuwin Injection to experience this side effect. If the condition persists or worsens, consult your doctor.
Lesuwin Injection facilitates the emptying of food from the stomach, thereby treating diabetic gastroparesis, a diabetes-related condition that causes food to remain in the stomach for prolonged periods.
It is used to treat severe indigestion, bloating, diabetic gastroparesis, and severe nausea or vomiting when oral medicines cannot be taken. Talk to your doctor for more details.
It is injected directly into a muscle or a vein by a trained healthcare professional. Talk to your doctor if you have questions about your administration schedule.
This medicine can cause drowsiness and dizziness in some people. Do not drive or operate machinery until you are certain of how the medicine affects you.
This medication is generally not recommended during pregnancy unless your doctor decides it is absolutely necessary. Talk to your doctor to understand the risks and benefits.
Do not use the injection if the solution is cloudy, discoloured, or contains visible particles. Contact your healthcare provider or pharmacist for a replacement.
Yes, it can sometimes increase a hormone called prolactin, which may lead to breast swelling, tenderness, or menstrual changes. Talk to your doctor if you experience these symptoms.
No, you should avoid alcohol as it can cause severe drowsiness when combined with this medicine. Talk to your doctor or pharmacist for more safety advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - LE83597
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