Leucoklin 50 Injection 5 ml

Leucoklin 50 Injection 5 ml is used to treat harmful effects caused by an overdose of methotrexate (cancer medicine). Methotrexate is used to treat cancer, severe rheumatoid arthritis, and severe psoriasis. It can cause fatal side effects sometimes. Harmful effects of methotrexate include vision loss, seizures/ fits, loss of consciousness, etc. Leucoklin 50 Injection 5 ml is also used to treat anemia (low amount of red blood cells) caused by low folic acid levels in the body. Leucoklin 50 Injection 5 ml is also used to treat colorectal cancer with the chemotherapeutic drug 5-fluorouracil (cancer that begins in the large intestine).

Leucoklin 50 Injection 5 ml contains leucovorin, which is a form of vitamin B. It is folic acid in its active form. Leucoklin 50 Injection 5 ml works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells. It should be administered as soon as possible after taking methotrexate.

Leucoklin 50 Injection 5 ml is given by a health care professional in a hospital or clinic setting. You may experience infections, nausea, vomiting, diarrhoea, and constipation. Most of these side effects of Leucoklin 50 Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before taking the Leucoklin 50 Injection 5 ml, tell your doctor about all your allergic or hypersensitivity reactions to medicines or food. Also, inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding or if you have anaemia, GI toxicity, renal impairment, or seizures.

Leucoklin 50 Injection 5 ml is used in the treatment of Overdose of methotrexate and Prevention of harmful effects of methotrexate. The detailed uses of Leucoklin 50 Injection 5 ml are as follows:

• Prevent toxicity from high-dose methotrexate: Leucoklin 50 Injection 5 ml is used as a rescue agent to protect healthy cells after methotrexate chemotherapy. It supplies reduced folate to bypass methotrexate’s blockade, minimizing damage to bone marrow, gastrointestinal lining, and other tissues.
• Treat methotrexate overdose: Leucoklin 50 Injection 5 ml counteracts the harmful effects of accidental or excessive methotrexate exposure by restoring folate activity and promoting drug clearance from the body.
• Enhance chemotherapy efficacy in colorectal cancer: Leucoklin 50 Injection 5 ml is combined with fluorouracil to improve its anti-cancer effects in advanced colorectal cancer. It stabilizes fluorouracil’s binding to target enzymes, increasing tumor cell death.

• Leucoklin 50 Injection 5 ml will be given by a healthcare provider. The timing and dosage are based on the patient’s needs and medical condition.
• Leucoklin 50 Injection 5 ml should be administered at a controlled rate by healthcare staff in a hospital setting.
• Do not self-administer.

Leucoklin 50 Injection 5 ml is used to prevent the harmful effects of methotrexate (cancer medicine) when methotrexate is used to treat some types of cancer. Leucoklin 50 Injection 5 ml is also used to treat patients who accidentally overdose on methotrexate or similar medicines. Leucoklin 50 Injection 5 ml works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells. Leucovorin injection is also used to treat anaemia (low red blood cell count) caused by low folic acid levels in the body. Leucoklin 50 Injection 5 ml is also used to treat colorectal cancer with the chemotherapeutic drug 5-fluorouracil (cancer that begins in the large intestine).

Inform your doctor about any allergic or hypersensitive reactions to medications or food before taking the Leucoklin 50 Injection 5 ml. Inform your doctor about your medical history and any other medications you are currently taking so that any potential side effects can be ruled out. Also, let your doctor know if you are pregnant, intend to become pregnant, or are breastfeeding. Do not use Leucoklin 50 Injection 5 ml in more than prescribed doses or for a longer duration as it may cause adverse effects.