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Levimir Flexipen 100 I.U 3Ml

Levimir Flexipen 100 I.U 3Ml

Prescription drug
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Manufacturer/Marketer

NOVO NORDISK A/S

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-25

About Levimir Flexipen 100 I.U 3Ml

Levimir Flexipen 100 I.U 3Ml is long-acting insulin analogue which belongs to the category of medicines called 'anti-diabetic' primarily used for the management and treatment of  type 1 and type 2 diabetes, especially in persons whose sugar levels are too high and cannot be only controlled by dieting and exercising. It is used to improve the sugar levels in blood in persons dealing with diabetes mellitus in both children (above 2 years of age) and adults. Diabetes occurs when the body does not produce enough insulin to control the level of blood sugar. It is a condition in which blood glucose levels are above average. Insulin is the hormone that controls sugar levels in your blood. 

Levimir Flexipen 100 I.U 3Ml contains Insulin Detemir as its active ingredient. It is a recombinant human insulin analogue that is equipotent to regular human insulin. It works by replacing the natural insulin produced by the body and helps in moving sugar from the blood to different body tissues where it is used as energy. Levimir Flexipen 100 I.U 3Ml has a more rapid onset of action and a long duration of action up to 24 hours of basal insulin coverage. Treatment with Levimir Flexipen 100 I.U 3Ml helps to prevent complications from your diabetes.

Your doctor will advise you on how to use the Levimir Flexipen 100 I.U 3Ml. It should be administered at least 0-15 minutes before or soon after meals. The common side effects of Levimir Flexipen 100 I.U 3Ml are hypokalaemia (low potassium levels), hypoglycemia (low blood sugar levels), local injection site reactions like lipodystrophy (fat deposition under the skin), rash, and pruritus (itch skin). Most of these side effects of Levimir Flexipen 100 I.U 3Ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not skip any doses or stop taking Levimir Flexipen 100 I.U 3Ml suddenly without consulting your doctor. Consult your doctor before taking Levimir Flexipen 100 I.U 3Ml if you are pregnant or breastfeeding. Levimir Flexipen 100 I.U 3Ml should not be given to children below 10 years. Avoid alcohol consumption while taking Levimir Flexipen 100 I.U 3Ml as it might increase side-effects. Levimir Flexipen 100 I.U 3Ml may cause hypoglycaemia, so drive only if you are alert. Inform your doctor about all the medications you are taking and your health condition to rule out any unpleasant side effects.

Uses of Levimir Flexipen 100 I.U 3Ml

Treatment of Type 1 and Type 2 Diabetes Mellitus.

Medicinal Benefits

Levimir Flexipen 100 I.U 3Ml belongs to the category of the anti-diabetic drug, indicated in the treatment of type 1 and type 2 diabetes . This medicine is primarily prescribed to people whose blood sugar levels are high and is not even controlled by diet and exercise alone. Levimir Flexipen 100 I.U 3Ml is a fast-acting form of insulin that helps lower blood sugar levels after the intake of food. It helps in improving the glycaemic control, which in turn decreases the risk of progression of complications of diabetes like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer, and others.

Directions for Use

Prefilled syringe/Injectable solution: Read the instruction leaflet before use. It is administered in the form of an injection under the skin. Inject it subcutaneously (under the skin) in the abdomen, thigh or upper arm. Use a different place on the body every time you give an injection to prevent damage to your skin. You can take it 15 minutes before a meal or immediately after food. Store the Levimir Flexipen 100 I.U 3Ml in a refrigerator or at room temperature and use it within 28 days. Do not freeze Levimir Flexipen 100 I.U 3Ml. Do not inject cold insulin because it might be painful.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Levimir Flexipen 100 I.U 3Ml

  • Local injection site reactions (such as reddening, unusually intense pain on injection, itching, hives, swelling, or inflammation)
  • Hypoglycemia (low blood sugar levels)
  • Hypokalaemia (low potassium levels)
  • Lipodystrophy (fat deposition under the skin)
  • Rash
  • Pruritus (itchy skin)

Drug Warnings

Do not take or stop this medicine, if the doctor did not advise you to do so. Brief your medical history to doctor if you have any heart, kidney or liver diseases, low blood sugar (hypoglycaemia), and low potassium levels in the blood (hypokalaemia) before starting Levimir Flexipen 100 I.U 3Ml. Do not share an injection pen, cartridge, or syringe with another person, even if the needle is changed. Do not inject Levimir Flexipen 100 I.U 3Ml daily at the same injection site since it may cause skin changes, such as lumps under the skin. Do not drive or operate machinery if you experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar. It is advised to avoid your alcohol intake while using Levimir Flexipen 100 I.U 3Ml to avoid low blood sugar levels further. Pregnant and breastfeeding women should consult their doctor before starting this medication. Levimir Flexipen 100 I.U 3Ml can be given safely to children provided, it is prescribed by a child specialist.

Drug Interactions

Drug-Drug Interaction: Levimir Flexipen 100 I.U 3Ml may have an interaction with drugs that may increase the risk of antiarrhythmic (disopyramide), hemorheological agents (pentoxifylline), antidiabetic medicinal products (pramlintide, glucagon), beta-blockers (metoprolol), diuretics (furosemide ), bleeding disorder drugs (octreotide), antipsychotic (propoxyphene, phenothiazines), estrogens, progestins (e.g. in oral contraceptives), protease inhibitors and atypical antipsychotic medicinal products (olanzapine and clozapine)., thyroid hormones (levothyroxine), anti-asthmatics (albuterol, epinephrine, terbutaline), antidepressant medications (fluoxetine, lithium), lipid-lowering pills (reserpine, niacin, clonidine, fenofibrate, guanethidine), pain killers (aspirin) and antibiotics (isoniazid).

Drug-Food Interaction: Levimir Flexipen 100 I.U 3Ml may interact with an ayurvedic, homoeopathy, Unani, herbal supplements, or OTC items. Tell your doctor if you are using these products. Try to avoid intake of alcoholic beverages with Levimir Flexipen 100 I.U 3Ml as it may increase or decrease your blood sugar level.

Drug-Disease Interaction: Levimir Flexipen 100 I.U 3Ml should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).
 

Drug-Drug Interactions Checker List

  • ASPIRIN
  • BUDESONIDE+FORMOTEROL
  • METOPROLOL
  • FUROSEMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and for some time after the physical activity.
  • Exercise may also speed up the effect of an insulin dose, especially if the exercise involves the area of the injection site (for example, the leg should not be used for injection just before running).
  • Discuss with your doctor how you should adjust your insulin regimen to accommodate exercise. 
  • Avoid eating sugar food and prefer food cooked food low in calories.
  • When travelling across more than 2 time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

Special Advise

  • Your doctor may tell you to keep a check on your potassium levels as prolonged administration causes hypokalemia (low potassium levels). 
  • Your doctor may advise regular monitoring of blood sugars.

Disease/Condition Glossary

Type 1 diabetes:  It is a condition in which your immune system destroys insulin-making cells in the pancreas. These are called beta cells and the pancreas produces little or no insulin. The condition is usually diagnosed in children and young people, so it used to be called juvenile diabetes.

Type 2 diabetes: It is a chronic or life-long condition in which cells of the body fail to respond to insulin, and in later stages, the body even fails to produce enough amount of insulin. It comprises around 90% of total diabetes cases. This condition makes the body rely on different energy sources in muscles, tissues, and organs. This disease develops gradually, and the early symptoms include constant hunger, lack of energy, fatigue, weight loss, excessive thirst, frequent urination, dry mouth, itchy skin, and blurry vision. Persons who are middle-aged or older are most likely to have type 2 diabetes, so it is also called adult-onset diabetes.

The risks of uncontrolled diabetes include damaged retina of eyes or blindness, loss of limbs, nerve problems, kidney problems, sexual dysfunction, and increase the possibility of heart attack or stroke.

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Levimir Flexipen 100 I.U 3Ml to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

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Pregnancy

Safe if prescribed

Levimir Flexipen 100 I.U 3Ml can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery.

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Breast Feeding

Safe if prescribed

Levimir Flexipen 100 I.U 3Ml can be given safely to nursing mothers but only under the supervision of a physician.

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Driving

Unsafe

Drive with caution, Levimir Flexipen 100 I.U 3Ml usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycemia (low blood sugar)

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Liver

Caution

Levimir Flexipen 100 I.U 3Ml to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Levimir Flexipen 100 I.U 3Ml to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Levimir Flexipen 100 I.U 3Ml can be given safely to children provided, it is prescribed by a child specialist.

Country of origin

India

Manufacturer/Marketer address

Plot No.32, 47-50, EPIP Area, Whitefield, Bangalore - 560 066
Other Info -

Author Details

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FAQs

Levimir Flexipen 100 I.U 3Ml contains Insulin Detemir that acts as an insulin analogue and lowers your blood glucose levels. Thus, Levimir Flexipen 100 I.U 3Ml helps in lowering the blood sugar levels in diabetic patients.
It is advised to tell your doctor if you are taking pioglitazone or rosiglitazone as taking Levimir Flexipen 100 I.U 3Ml with these medicines can significantly lower sugar level thereby increasing the risk of serious heart problems.
Levimir Flexipen 100 I.U 3Ml can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Levimir Flexipen 100 I.U 3Ml can be given to you or not depending on your present condition. Levimir Flexipen 100 I.U 3Ml should be avoided in patients who are allergic to Levimir Flexipen 100 I.U 3Ml or other forms of insulin, patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycemia), and low potassium level (hypokalaemia).
Insulin is a cold chain medicine, and it has to be stored between 2-8 degree celsius only. So, keeping Insulin out of the refrigerator will decrease its efficacy. And thus it will be not able to lower your blood sugar significantly. So, it is advisable to keep Levimir Flexipen 100 I.U 3Ml between 2-8 degree celsius or in the refrigerator and not in the freezer.
Insulin is released from the beta cells of your pancreas in response to the rise in blood sugar (glucose) in your bloodstream. After you have consumed a meal, any carbohydrate you have eaten is broken down into the simpler form of glucose called monosaccharides or disaccharides and then transferred into the bloodstream for further metabolism and utilization. Thus pancreas detects this rise in blood glucose and starts to secrete insulin.
Habitual moderate coffee drinking has actually been associated with increased insulin sensitivity. But in acute and high doses, caffeine can decrease insulin sensitivity and raise plasma insulin levels.
Your doctor will tell you when and what dose you should take your insulin depending on your present conditions.

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Keep Refrigerated. Do not freeze.