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Composition :

LINEZOLID-600MG

Manufacturer/Marketer :

Epitome Life Science

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Lewise-600 Tablet

Lewise-600 Tablet is used to treat bacterial infections of the skin and lungs (pneumonia). It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. Lewise-600 Tablet does not work against infections caused by the virus, including cold and flu.

Lewise-600 Tablet contains Linezolid, which works by inhibiting the bacteria's ability to produce proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

In some cases, you may experience common side effects, such as thrush (a fungal infection), headache, a metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Lewise-600 Tablet on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. Consult your doctor if you are pregnant or planning to become pregnant before taking Lewise-600 Tablet. Lewise-600 Tablet passes into breastmilk, so do not take Lewise-600 Tablet if you are breastfeeding. Lewise-600 Tablet may cause dizziness and vision problems; therefore, exercise caution when driving and operating machinery. Avoid alcohol consumption while taking Lewise-600 Tablet, as it may cause increased dizziness.

Uses of Lewise-600 Tablet

Lewise-600 Tablet is used in the treatment of bacterial infections caused by Gram-positive bacteria. The detailed uses of Lewise-600 Tablet are as follows:<br/> • Pneumonia (Lung Infection): Lewise-600 Tablet is effective in treating both community-acquired and hospital-acquired pneumonia caused by susceptible bacteria.<br/> • Skin and Skin Structure Infections: Lewise-600 Tablet is used to treat mild to severe bacterial infections of the skin and its underlying tissues. It is also indicated for the treatment of diabetic foot infections, without associated bone infections (osteomyelitis).<br/> • Antibiotic-Resistant Infections: Lewise-600 Tablet is indicated for infections caused by the bacteria Enterococcus faecium that are resistant to vancomycin, including intra-abdominal infections, skin and soft tissue infections, urinary tract infections, and concurrent bacteremia (presence of bacteria in the bloodstream).<br/>

Directions for Use

  • Lewise-600 Tablet can be taken with or without food, as advised by your doctor.
  • Your doctor will decide the appropriate dosage and timing based on your medical condition.
  • Swallow Lewise-600 Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

Medicinal Benefits

Lewise-600 Tablet belongs to the class of antibiotics called oxazolidinones, used to treat bacterial infections of the skin and lungs (pneumonia). It is also effective in treating vancomycin-resistant enterococcal infections, diabetic foot infections, intra-abdominal infections, urinary tract infections, and concurrent bacteremia (presence of bacteria in the bloodstream). Lewise-600 Tablet contains Linezolid, which works by stopping the growth of infection-causing bacteria. Thus, it helps treat the bacterial infection.

How Lewise-600 Tablet Works

Lewise-600 Tablet contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Lewise-600 Tablet

Do not take more than the prescribed dose of Lewise-600 Tablet, as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Do not take Lewise-600 Tablet if you are allergic to any of its contents; if you are taking or have taken monoamine oxidase (MAO) inhibitors in the last 14 days. Talk to your doctor if you have high blood pressure, an overactive thyroid, phaeochromocytoma (tumour of adrenal glands), carcinoid syndrome (tumours of the hormone system), manic depression, schizophrenia, confusion, or other mental problems. Inform your doctor if you bruise or bleed easily, have anaemia (low red blood cells), are prone to infections, have a history of seizures, are on dialysis, have diarrhoea, or kidney or liver problems. Consult your doctor immediately if you experience a throbbing headache after eating or drinking, vision problems, loss of sensation or tingling and prickling sensations in your arms and legs, persistent diarrhoea, nausea, vomiting, abdominal pain, or rapid breathing. Consult your doctor if you are pregnant before taking Lewise-600 Tablet. Lewise-600 Tablet passes into breastmilk, so do not take Lewise-600 Tablet if you are breastfeeding. Lewise-600 Tablet may cause dizziness and vision problems; therefore, exercise caution when driving and operating machinery. Avoid alcohol consumption while taking Lewise-600 Tablet, as it may cause increased dizziness.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Lewise-600 Tablet:
Taking Lewise-600 Tablet with Methylphenidate together may increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Lewise-600 Tablet with Methylphenidate is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden and severe headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, contact a doctor immediately. You may use methylphenidate only after you have been off Lewise-600 Tablet for at least 14 days. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lewise-600 Tablet:
Using Lewise-600 Tablet together with mirtazapine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Lewise-600 Tablet with Mirtazapine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidCaffeine
Critical
How does the drug interact with Lewise-600 Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Caffeine with Lewise-600 Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Lewise-600 Tablet:
Taking Duloxetine with Lewise-600 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Duloxetine with Lewise-600 Tablet is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lewise-600 Tablet:
When Oxcarbazepine is taken with Lewise-600 Tablet, it can increase the risk of serotonin syndrome(a condition when your body has too much of a chemical called serotonin), further leading to side effects.

How to manage the interaction:
Taking Oxcarbazepine with Lewise-600 Tablet is not recommended, as it results in an interaction, it can be taken if advised by a doctor. However, if you experience symptoms such as confusion, hallucination (seeing or hearing things that do not exist), seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Lewise-600 Tablet:
Taking Lewise-600 Tablet and Mephentermine together may cause high blood pressure.

How to manage the interaction:
Taking Mephentermine with Lewise-600 Tablet is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lewise-600 Tablet:
Taking Lewise-600 Tablet with Fentanyl may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Lewise-600 Tablet and Fentanyl, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lewise-600 Tablet:
Using Lewise-600 Tablet together with cyproheptadine may increase side effects of Cyproheptadine.

How to manage the interaction:
Taking Cyproheptadine with Lewise-600 Tablet is not recommended, consult a doctor before taking it. Contact a doctor if you experience dizziness, drowsiness, blurred vision, dry mouth, constipation, heat intolerance, flushing, decreased sweating, difficulty urinating, palpitation, rapid heartbeat, confusion, disorientation, and memory problems. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lewise-600 Tablet:
Coadministration of Lewise-600 Tablet with Imipramine might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Lewise-600 Tablet and Imipramine together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lewise-600 Tablet:
Co-administration of Lewise-600 Tablet with Vortioxetine can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Lewise-600 Tablet with Vortioxetine can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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LINEZOLID-600MGTyramine-containing food
Severe

Drug-Food Interactions

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LINEZOLID-600MGTyramine-containing food
Severe
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Taking high tyramine-containing food along with Lewise-600 Tablet can cause blood pressure to rise to exceedingly high levels, a condition known as a hypertensive crisis (Severely elevated blood pressure). Avoid high tyramine-containing food while taking Lewise-600 Tablet. Consult a doctor, if you experience severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body).

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yogurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
  • Eat fibre-rich food like whole grains, lentils, berries, broccoli, peas, and bananas.
  • Avoid foods rich in calcium, grapefruit, and grapefruit juice, as they might hinder the absorption of antibiotics.
  • Avoid consuming tyramine-rich food or drinks, such as meat, cheese, fish, red wine, beer, certain beans, and fermented yeast products.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Unsafe

Avoid consuming alcohol while taking Lewise-600 Tablet, as it may cause increased dizziness.

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Pregnancy

Caution

Lewise-600 Tablet belongs to pregnancy category C. If you are pregnant, please consult your doctor before using Lewise-600 Tablet. Your doctor will prescribe it only if the potential benefits justify the possible risks.

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Breast Feeding

Unsafe

Avoid taking Lewise-600 Tablet if you are breastfeeding, as it may pass into breast milk and cause harmful effects in the baby.

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Driving

Unsafe

Lewise-600 Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be necessary if you have liver impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Kidney

Caution

Dose adjustment may be necessary if you have kidney impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Children

Unsafe

Lewise-600 Tablet is not recommended for children below 18 years of age.

Have a query?

FAQs

Lewise-600 Tablet is an antibiotic medication used to treat bacterial infections of the skin and lungs (pneumonia). It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.

Lewise-600 Tablet contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

Diarrhoea might be a side effect of Lewise-600 Tablet. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain, stop taking Lewise-600 Tablet and consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Lewise-600 Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking Lewise-600 Tablet for as long as your doctor has prescribed it.

Lewise-600 Tablet may cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Do not take Lewise-600 Tablet on your own, as self-medication may lead to antibiotic-resistance, in which antibiotics fail to act against specific bacterial infections.

Lewise-600 Tablet may affect certain laboratory test results, such as blood tests, blood sugar tests, liver and kidney function tests. Inform the person doing the tests that you are taking Lewise-600 Tablet.

Lewise-600 Tablet may cause anaemia due to a decrease in the number of red blood cells. This could also cause unexplained bleeding or bruising. Consult your doctor if you experience unexplained bleeding or bruising.

Consult your doctor before taking Lewise-600 Tablet if you have hypertension (high blood pressure), as it may cause an increase in blood pressure.

You should avoid taking large quantities of food that contains high tyramine. Foods that are fermented, cured, aged or spoiled contain a high amount of tyramine, e.g. cheese, red wine, pickles, overripe fruits etc. Consuming tyramine while taking Linezolid can result in an elevation of blood pressure, which may result in an emergency.

You should take it twice a day, every 12 hours, for example, at 8 a.m. and 8 p.m. You can take it before, with, or after food. Your doctor or clinician will determine the duration of the treatment course.

Some foods containing tyramine can increase your blood pressure when taking this medicine. You should avoid the following types of foods include Mature or aged cheese, aged, smoked, pickled, or cured meats/fish/poultry such as salami, liver, pickled herring, chocolate (more than 50gm), avocados or any over-ripe fruit, broad beans, sauerkraut, sourdough bread, protein diet supplement etc.

Lewise-600 Tablet may cause diarrhoea, which can be severe in some cases. It may occur two months or more after you stop taking it. Do not take any medicine to treat diarrhoea without first checking with your doctor. If you have any questions, check with your doctor.

Lewise-600 Tablet is indicated for the treatment of gram-positive infections and is approved for treating skin and skin structure infections, bacterial pneumonia, and vancomycin-resistant enterococcal (VRE) infections, including those complicated by bacteremia.

Lewise-600 Tablet disrupts bacterial growth by inhibiting the initiation process of protein synthesis.

It is usually taken with or without food or as directed by the doctor.

Common side effects of Lewise-600 Tablet may include thrush (fungal infection), headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please consult your doctor. Lewise-600 Tablet should be used during pregnancy or breastfeeding only if needed, and the benefit outweighs the risk to the fetus.

Avoid consuming alcohol while taking Lewise-600 Tablet, as it may cause increased dizziness.

Take the missed dose as soon as you remember, unless it is almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

13/361,369 Panchratna estate, b/h Ankur old factory, Opp. Bhagyoday hotel, Changodar T.A. Sanand , Ahmedabad, India, 380001
Other Info - LEW0012

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