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compositionComposition:LINEZOLID-600MG
prescriptionPrescription Medicine

Linokem-600 Tablet is an antibiotic medication used to treat bacterial infections of the skin and soft tissues, lungs (pneumonia) and bloodstream infections. It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

LINEZOLID-600MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Linokem-600 Tablet

Linokem-600 Tablet is used to treat bacterial infections of the lungs (pneumonia), skin and soft tissues. It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body.

Linokem-600 Tablet contains Linezolid, which inhibits bacterial protein synthesis, thereby killing the bacteria.

You may experience common side effects, such as headache, a metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Do not take Linokem-600 Tablet on your own, as it may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. Consult your doctor if you are pregnant or planning to become pregnant before taking Linokem-600 Tablet .

Uses of Linokem-600 Tablet

Linokem-600 Tablet is used in the treatment of bacterial infections caused by Gram-positive bacteria. The detailed uses of Linokem-600 Tablet are as follows:

  • Pneumonia (Lung Infection): Linokem-600 Tablet is effective in treating both community-acquired and hospital-acquired pneumonia caused by susceptible bacteria.
  • Skin and Skin Structure Infections: Linokem-600 Tablet is used to treat mild to severe bacterial infections of the skin and its underlying tissues. It is also indicated for the treatment of diabetic foot infections, without associated bone infections (osteomyelitis).
  • Antibiotic-Resistant Infections: Linokem-600 Tablet is indicated for infections caused by the bacteria Enterococcus faecium that are resistant to vancomycin, including intra-abdominal infections, skin and soft tissue infections, urinary tract infections, and concurrent bacteremia (presence of bacteria in the bloodstream).

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Directions for Use

  • Linokem-600 Tablet can be taken with or without food, as advised by your doctor.
  • Your doctor will decide the appropriate dosage and timing based on your medical condition.
  • Swallow Linokem-600 Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

Key Benefits

For Pneumonia:

  • Cures pneumonia brought on by resistant gram-positive bacteria.
  • Beneficial for ventilator-associated pneumonia and pneumonia acquired in hospitals.
  • Relieves the symptoms of infection, breathing and fever when other antibiotics are ineffective.
  • Ideal for people who don't react to or can't handle other antibiotics.

For soft skin structures:

  • Beneficial for complex soft tissue and skin infections, such as cellulitis, abscesses, and wound infections.
  • Ensures efficient infection control by having good penetration into soft tissues and skin.
  • Aids in lowering infection-related discomfort, redness, swelling, and pus production.

For Vancomycin-resistant enterococcal infections

  • Beneficial for severe infections include bloodstream infections, intra-abdominal infections, and complex Vancomycin-resistant enterococcal infections.
  • When other antibiotics are ineffective or poorly tolerated, it helps patients achieve better clinical results.

How Linokem-600 Tablet Works

Linokem-600 Tablet contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Linokem-600 Tablet

Do not take more than the prescribed dose of Linokem-600 Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Linokem-600 Tablet if you are allergic to any of its contents or if you are taking or have taken monoamine oxidase (MAO-antidepressants) inhibitors in the last 14 days.
  • Talk to your doctor if you have high blood pressure, an overactive thyroid, phaeochromocytoma (tumour of adrenal glands), carcinoid syndrome (tumours of the hormone system), manic depression, schizophrenia, confusion, or other mental problems.
  • Consult your doctor if you are pregnant before taking Linokem-600 Tablet .
  • Linokem-600 Tablet passes into breastmilk, so do not take Linokem-600 Tablet if you are breastfeeding.
  • Linokem-600 Tablet may cause dizziness and vision problems; therefore, exercise caution when driving and operating machinery.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Linokem-600 Tablet:
Taking Linokem-600 Tablet and Mephentermine together may cause high blood pressure.

How to manage the interaction:
Taking Mephentermine with Linokem-600 Tablet is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Linokem-600 Tablet:
Using Linokem-600 Tablet together with mirtazapine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Linokem-600 Tablet with Mirtazapine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Linokem-600 Tablet:
Co-administration of Linokem-600 Tablet with Vortioxetine can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Linokem-600 Tablet with Vortioxetine can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Linokem-600 Tablet:
Co-administration of Linokem-600 Tablet with Tramadol can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Linokem-600 Tablet with Tramadol is not recommended, consult a doctor before taking it. Consult a doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not stop using any medications without talking to a doctor.
How does the drug interact with Linokem-600 Tablet:
Coadministration of Entacapone with Linokem-600 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Entacapone with Linokem-600 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidCaffeine
Critical
How does the drug interact with Linokem-600 Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Caffeine with Linokem-600 Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Linokem-600 Tablet:
Taking Duloxetine with Linokem-600 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Duloxetine with Linokem-600 Tablet is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Linokem-600 Tablet:
Using Carbamazepine with Linokem-600 Tablet can cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Carbamazepine and Linokem-600 Tablet together is not recommended, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Linokem-600 Tablet:
Taking Linokem-600 Tablet with Epinephrine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Linokem-600 Tablet with Epinephrine is not recommended as it can result in an interaction. It should be taken only if a doctor has advised it. However, if you experience confusion, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Linokem-600 Tablet:
Taking Linokem-600 Tablet with Amitriptyline can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Linokem-600 Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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LINEZOLID-600MGTyramine-containing food
Severe

Drug-Food Interactions

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LINEZOLID-600MGTyramine-containing food
Severe
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Taking high tyramine-containing food along with Linokem-600 Tablet can cause blood pressure to rise to exceedingly high levels, a condition known as a hypertensive crisis (Severely elevated blood pressure). Avoid high tyramine-containing food while taking Linokem-600 Tablet. Consult a doctor, if you experience severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body).

Diet & Lifestyle Advise

Eating changes:

  • Avoid foods like salami, smoked meats, red wine, beer, pickles, soy sauce, aged cheeses, and fermented foods.
  • Consume foods that are newly cooked rather than ones that are aged or preserved.
  • Eat a diet rich in fruits, vegetables, whole grains, and lean meats to stay balanced.

Physical activity:

  • As tolerated, engage in mild-to-moderate exercise, such as walking or gentle stretching.
  • Ensure adequate sleep to support the healing process after an infection.

Environment changes:

  • To reduce the risk of developing or worsening infections, stay in a clean, well-ventilated environment.
  • Avoid dusty or congested areas, particularly during treatment for severe diseases.
  • Keep your house and workplace clean and practice good hand hygiene.

Stress management:

  • To manage stress and blood pressure, engage in mindfulness, meditation, or deep breathing exercises.
  • To lessen mental stress, get emotional support from friends or family.

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

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Alcohol

Unsafe

Avoid consuming alcohol while taking Linokem-600 Tablet , as it may cause increased dizziness.

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Pregnancy

Consult your doctor

Linokem-600 Tablet belongs to pregnancy category C. If you are pregnant, please consult your doctor before using Linokem-600 Tablet . Your doctor will prescribe it only if the potential benefits justify the possible risks.

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Breast Feeding

Unsafe

Avoid taking Linokem-600 Tablet if you are breastfeeding, as it may pass into breast milk and cause harmful effects in the baby.

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Driving

Caution

Linokem-600 Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be necessary if you have liver impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Kidney

Caution

Dose adjustment may be necessary if you have kidney impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Children

Unsafe

Linokem-600 Tablet is not recommended for children below 18 years of age.

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Heart

Caution

Linokem-600 Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Linokem-600 Tablet to geriatric patients. Your doctor will prescribe Linokem-600 Tablet if the benefits outweigh the risks.

FAQs

Linokem-600 Tablet is an antibiotic medication used to treat bacterial infections of the skin and lungs (pneumonia). It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.

Linokem-600 Tablet contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

Diarrhoea might be a side effect of Linokem-600 Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain, stop taking Linokem-600 Tablet and consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Linokem-600 Tablet even if you feel better, as it is an antibiotic, and leaving it in between may lead to even more severe infection. To treat your condition effectively, continue taking Linokem-600 Tablet for as long as your doctor has prescribed it.

Linokem-600 Tablet may cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Do not take Linokem-600 Tablet on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections.

Linokem-600 Tablet may affect certain laboratory test results, such as blood tests, blood sugar tests, and liver and kidney function tests. Inform the person doing the tests that you are taking Linokem-600 Tablet .

Linokem-600 Tablet may cause anaemia due to a decrease in the number of red blood cells. This could also cause unexplained bleeding or bruising. Consult your doctor if you experience unexplained bleeding or bruising.

Consult your doctor before taking Linokem-600 Tablet if you have hypertension (high blood pressure), as it may cause an increase in blood pressure.

You should avoid taking large quantities of food that contains high tyramine. Foods that are fermented, cured, aged or spoiled contain a high amount of tyramine, e.g. cheese, red wine, pickles, overripe fruits, etc. Consuming tyramine while taking Linezolid can result in an elevation of blood pressure, which may result in an emergency.

You should take it twice a day, every 12 hours, for example, at 8 a.m. and 8 p.m. You can take it before, with, or after food. Your doctor or clinician will determine the duration of the treatment course.

Linokem-600 Tablet is indicated for the treatment of gram-positive infections and is approved for treating skin and skin structure infections, bacterial pneumonia, and vancomycin-resistant enterococcal (VRE) infections, including those complicated by bacteremia.

It is usually taken with or without food or as directed by the doctor.

Common side effects of Linokem-600 Tablet may include thrush (fungal infection), headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please consult your doctor. Linokem-600 Tablet should be used during pregnancy or breastfeeding only if needed, and the benefit outweighs the risk to the fetus.

Avoid consuming alcohol while taking Linokem-600 Tablet , as it may cause increased dizziness.

Take the missed dose as soon as you remember, unless it is almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - LIN0089

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