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  3. LICOLATE INJECTION 1ML

LICOLATE INJECTION 1ML, Pack of 1 Injection
LICOLATE INJECTION 1ML, Pack of 1 Injection
LICOLATE INJECTION 1ML, Pack of 1 Injection
LICOLATE INJECTION 1ML, Pack of 1 Injection
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

LICOLATE INJECTION 1ML contains glycopyrrolate, which works by inhibiting the action of acetylcholine. It is used to reduce secretions from the mouth, throat, or stomach (such as saliva or stomach acid), to avoid cardiac rhythm issues during anaesthesia, intubation, or surgery. Some of the common side effects include blurred vision, palpitations, urinary retention, and decreased sweating.

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Composition :

GLYCOPYRROLATE-0.2MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About LICOLATE INJECTION 1ML

LICOLATE INJECTION 1ML is used to reduce secretions from the mouth, throat, or stomach (such as saliva or stomach acid), to avoid cardiac rhythm issues during anesthesia, intubation, or surgery, or to minimize side effects from specific medications (such as pyridostigmine and neostigmine).

LICOLATE INJECTION 1ML contains 'Glycopyrrolate', which works by inhibiting the action of acetylcholine. Thus, reduces gastric secretions' volume and free acidity and controls excessive pharyngeal, bronchial, and tracheal secretions.

LICOLATE INJECTION 1ML will be administered by a healthcare professional; do not self-administer. In some cases, LICOLATE INJECTION 1ML may cause dry mouth, urinary retention and hesitancy, blurred vision, palpitations, and decreased sweating. Most of these side effects of LICOLATE INJECTION 1ML do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to any components in LICOLATE INJECTION 1ML. Consult your doctor if you are pregnant or breastfeeding. LICOLATE INJECTION 1ML may cause drowsiness and blurred vision, do not drive or operate machinery unless you are alert. Let your doctor know if you are taking prescription and non-prescription medications, including vitamins and herbal supplements.

Uses of LICOLATE INJECTION 1ML

LICOLATE INJECTION 1ML is used to treat various medical conditions. The detailed uses are as follows:

  • Reduction of preoperative secretions: It decreases saliva, tracheobronchial, and pharyngeal secretions to help maintain a clear airway during surgery.
  • Prevention and treatment of intraoperative bradycardia: It helps manage a slow heart rate during anaesthesia or surgical procedures.
  • Adjunct to anaesthesia: It minimises airway secretions and suppresses certain reflexes during anaesthesia, improving surgical safety and patient comfort.

Directions for Use

  • LICOLATE INJECTION 1ML is administered by a qualified healthcare professional, typically in a hospital or clinic setting.
  • Your doctor will determine the appropriate dose and frequency based on your medical condition.
  • Follow your healthcare provider's instructions about the medication and any steps to track your progress or precautions during treatment.

Medicinal Benefits

  • LICOLATE INJECTION 1ML contains Glycopyrrolate, which belongs to the group of medicines called anticholinergics.
  • Used during anaesthesia to reduce airway and gastric secretions, including the volume and acidity of gastric secretions.
  • Helps block cardiac inhibitory reflexes during induction of anaesthesia and intubation.
  • Used during surgery to manage arrhythmias caused by surgery, drugs, or vagal reflexes.
  • Protects against peripheral muscarinic effects of cholinergic agents.
  • Also used as adjunct therapy for treating peptic ulcers when an immediate anticholinergic effect is needed or when oral medication is not possible.
  • Works by inhibiting acetylcholine, thereby reducing gastric acidity and controlling excessive pharyngeal, bronchial, and tracheal secretions.

How LICOLATE INJECTION 1ML Works

LICOLATE INJECTION 1ML contains Glycopyrrolate, which works by blocking the action of acetylcholine, a chemical messenger involved in muscle contraction and secretion production. This action reduces the volume and acidity of gastric secretions and helps control excessive secretions in the mouth, throat, and airways, making it useful during surgery and certain medical conditions.

Storage

• Store in a cool and dry place away from sunlight.• Keep LICOLATE INJECTION 1ML out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of LICOLATE INJECTION 1ML

LICOLATE INJECTION 1ML is a parenteral formulation, hence the chance of overdose may be less. However, keep a track of your medicine as an overdose of LICOLATE INJECTION 1ML may cause serious side effects such as blurred vision. confusion, dizziness, faintness, etc. Reach the nearest hospital if you observe any of these side effects.

Drug Warnings

  • Inform your doctor if you are allergic to any medicines or foods.
  • Before receiving this injection, tell your doctor if you have any medical conditions such as glaucoma, bowel or bladder blockage, heart disease, irregular heartbeat, heart failure, high blood pressure, overactive thyroid, kidney or liver problems, muscle weakness, severe ulcerative colitis, toxic megacolon, or if you are very weak.
  • Let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding.
  • Inform your doctor about all prescription and non-prescription medicines, vitamins, supplements, and herbal products you are taking to avoid interactions.
  • This medicine should be given only by a healthcare professional in a clinical setting where monitoring is available.

Drug-Drug Interactions

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Glycopyrronium bromideDigoxin
Severe
Glycopyrronium bromideLevodopa
Severe

Drug-Drug Interactions

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Glycopyrronium bromideDigoxin
Severe
How does the drug interact with Licolate Injection 1ml:
Co-administration of Digoxin and Licolate Injection 1ml may increase the serum concentration of Digoxin and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Digoxin and Licolate Injection 1ml, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Glycopyrronium bromideLevodopa
Severe
How does the drug interact with Licolate Injection 1ml:
Coadministration of levodopa with Licolate Injection 1ml can significantly decrease the blood levels of levodopa.

How to manage the interaction:
Although using Licolate Injection 1ml and levodopa together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without a doctor's advice.
Glycopyrronium bromidePramlintide
Severe
How does the drug interact with Licolate Injection 1ml:
Taking Pramlintide with Licolate Injection 1ml can cause slow stomach emptying or slow the intestinal absorption of nutrients.

How to manage the interaction:
Although using Pramlintide and Licolate Injection 1ml together can lead to an interaction, it can be taken if advised by your doctor.
Glycopyrronium bromidePotassium chloride
Severe
How does the drug interact with Licolate Injection 1ml:
The use of Potassium chloride and Licolate Injection 1ml can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Using Potassium chloride and Licolate Injection 1ml together can lead to an interaction, however, it can be taken if advised by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Glycopyrronium bromideSecretin
Severe
How does the drug interact with Licolate Injection 1ml:
The combined use of secretin and Licolate Injection 1ml can inhibit gastric acid secretion.

How to manage the interaction:
Although using secretin and Licolate Injection 1ml together can lead to an interaction, it can be taken if advised by your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Peptic ulcers:
  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight through regular exercise.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as they might increase the pressure on the abdomen, leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat, spicy, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
  • Avoid sitting continuously, as it may trigger acidity. Take a break of 5 minutes every hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS

LICOLATE INJECTION 1ML Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is best to avoid alcohol while taking LICOLATE INJECTION 1ML, as it can increase side effects like drowsiness, dizziness, blurred vision, and dry mouth. Combining the two may also impair judgment and coordination. Speak to your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Inform your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding; your doctor will decide whether LICOLATE INJECTION 1ML can be given to breastfeeding mothers or not.

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Driving

Caution

LICOLATE INJECTION 1ML may cause drowsiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Please inform your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please inform your doctor if you have kidney problems.

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Children

Caution

LICOLATE INJECTION 1ML is generally not recommended for children unless prescribed by a doctor. Safety and effectiveness can vary with age, and the dose must be carefully adjusted by a healthcare professional based on medical need. Always follow your doctor’s advice before giving this medicine to a child.

Have a query?

FAQs

LICOLATE INJECTION 1ML is used to reduce secretions from the mouth, throat, or stomach (such as saliva or stomach acid), to avoid cardiac rhythm issues during anesthesia, intubation, or surgery, or to minimize side effects from specific medications (such as pyridostigmine and neostigmine).

Dry mouth could be a side effect of LICOLATE INJECTION 1ML. Limiting caffeine intake, avoiding smoking, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva, thereby preventing drying of the mouth.

LICOLATE INJECTION 1ML may cause heat prostration (overheating of the body due to severe weather conditions). You are advised to avoid high environmental temperatures.

LICOLATE INJECTION 1ML may cause mydriasis (pupil dilation) and increased intraocular pressure in patients with glaucoma. Inform your doctor if you have glaucoma or ocular hypertension.

LICOLATE INJECTION 1ML may cause tachycardia (increased heart rate). Inform your doctor if you have heart rate problems. LICOLATE INJECTION 1ML should be used with caution in patients with cardiac arrhythmia, congestive heart failure, coronary artery disease, high blood pressure, and hyperthyroidism.

LICOLATE INJECTION 1ML works by inhibiting the action of acetylcholine. Thus, it reduces the volume and free acidity of gastric secretions and controls excessive pharyngeal, bronchial, and tracheal secretions.

Country of origin

INDIA
Other Info - LIC0012

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 12:08 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210997s000lbl.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=62267afe-1a73-4623-984e-646db590ec5b&type=display
  3. https://pdf.hres.ca/dpd_pm/00044183.PDF

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