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Prescription drug
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Manufacturer/Marketer

Crescent Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About LIMBITROL TABLET

LIMBITROL TABLET is used to treat moderate to severe depression associated with moderate to severe anxiety. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss. Anxiety is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety and depression can occur at the same time.

LIMBITROL TABLET is a combination of two drugs: Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). Amitriptyline works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. 

You are advised to take LIMBITROL TABLET only for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Do not take LIMBITROL TABLET if you are pregnant, as it may cause birth defects. Consult your doctor before taking LIMBITROL TABLET if you are breastfeeding. Avoid driving or operating machinery as LIMBITROL TABLET causes sleepiness and dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with LIMBITROL TABLET as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of LIMBITROL TABLET

Treatment of Depression associated with anxiety

Medicinal Benefits

LIMBITROL TABLET is a combination of two drugs: Amitriptyline and Chlordiazepoxide. LIMBITROL TABLET is used to treat moderate to severe depression and anxiety. Amitriptyline is a tricyclic anti-depressant that affects certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide is a benzodiazepine anxiolytic that works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. LIMBITROL TABLET has a calming effect on various functions of the brain. Thereby, LIMBITROL TABLET helps in treating anxiety and depression.

Side Effects of LIMBITROL TABLET

  • Drowsiness
  • Dry mouth
  • Nasal congestion
  • Constipation
  • Blurred vision
  • Dizziness
  • Bloating

Directions for Use

Take LIMBITROL TABLET with or without food. Swallow LIMBITROL TABLET as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take LIMBITROL TABLET if you are allergic to any of its contents, if you recently had a heart attack or heart problems, are taking monoamine oxidase inhibitors (MAOI). Do not take opioids with LIMBITROL TABLET as it may result in increased sedation, depression, coma and death. LIMBITROL TABLET should not be taken for longer durations as it may cause physical dependence. Inform your doctor before taking LIMBITROL TABLET if you have bipolar disorder, eye problems, urination problems, seizures, thyroid problems, kidney or liver problems or if you are due to have any surgery. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Talk to your doctor before taking LIMBITROL TABLET if you have a history of drug abuse, addiction or alcohol abuse as LIMBITROL TABLET may cause dependence. Do not take LIMBITROL TABLET if you are pregnant, as it may cause birth defects. Consult your doctor before taking LIMBITROL TABLET if you are breastfeeding. Avoid driving or operating machinery as LIMBITROL TABLET causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with LIMBITROL TABLET as it could lead to increased drowsiness and dizziness. LIMBITROL TABLET should not be given to children as safety and effectiveness have not been established.

Therapeutic Class

PSYCHOTHERAPEUTICS

Drug Interactions

Drug-Drug Interactions: LIMBITROL TABLET may interact with an anti-depressant (duloxetine, venlafaxine), anti-convulsant (gabapentin, pregabalin, topiramate), anti-thyroid (levothyroxine), anti-anxiety (alprazolam), corticosteroid (fluticasone), beta-agonist (salmeterol), anti-anxiety (lorazepam), opioid analgesic (morphine) and diuretic (furosemide).

Drug-Food Interactions: Avoid consuming alcohol along with LIMBITROL TABLET as it may cause increased sedative effects.

Drug-Disease Interactions: Inform your doctor if you have closed-angle glaucoma, respiratory depression, seizures, low blood pressure, pheochromocytoma (tumour of the adrenal gland), porphyria, bone marrow suppression, obesity, diabetes, schizophrenia, glaucoma, bipolar disorder, thyroid disorder, urinary retention, tardive dyskinesia (involuntary facial movements), heart, liver or kidney problems.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • VENLAFAXINE
  • GABAPENTIN
  • PREGABALIN
  • TOPIRAMATE
  • LEVOTHYROXINE SODIUM
  • ALPRAZOLAM
  • LORAZEPAM
  • FLUTICASONE+SALMETEROL
  • FUROSEMIDE
  • MORPHINE

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products and certain fruits and vegetables help in the proper maintenance of neurotransmitters.

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improving mood, boosting self-esteem and providing restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

Yes

What if I have taken an overdose of LIMBITROL TABLET

Do not take more than the prescribed dose of LIMBITROL TABLET as it may cause overdose. The symptoms of overdose include difficulty sleeping, disorientation, dizziness, blurred vision, confusion, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, headache, loss of consciousness, fast/slow/irregular heartbeat, hallucinations, mood or other mental changes, seeing/hearing/feeling things that are not there, nightmares, seizures (fits), sweating, trouble breathing, unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness, or unusual excitement, nervousness, restlessness, or irritability. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Special Advise

  • Do not stop taking LIMBITROL TABLET on your own; sudden stopping of LIMBITROL TABLET may cause withdrawal symptoms. Consult your doctor if you have any concerns, the doctor may reduce the dose gradually.

  • Consult your doctor immediately if you develop any suicidal thoughts.

  • Women of childbearing age should use effective contraception while taking LIMBITROL TABLET.

Disease/Condition Glossary

Depression: It is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use and medical conditions. Symptoms of depression include loss of interest, hopelessness, difficulty concentrating, appetite changes, irritability, feeling of emptiness, sadness and restlessness.

Anxiety: It is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety is the body’s natural response to stress, in which the feeling of fear may be intense and debilitating. It is the most common form of emotional disorder and can affect anyone, at any age. Anxiety may cause a panic attacks, obsessive-compulsive disorder and post-traumatic stress disorder. The exact cause of anxiety is unknown, but it might be due to genetic or environmental factors. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating and difficulty falling asleep.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking LIMBITROL TABLET as it may cause increased sleepiness and dizziness.

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Pregnancy

Unsafe

Avoid taking LIMBITROL TABLET if you are pregnant unless prescribed by a doctor as it may cause birth defects.

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Breast Feeding

Caution

Consult your doctor before taking LIMBITROL TABLET; your doctor will decide whether LIMBITROL TABLET can be taken by breastfeeding mothers or not.

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Driving

Unsafe

LIMBITROL TABLET may cause sleepiness, dizziness and might impair thinking and motor skills. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

LIMBITROL TABLET should not be given to children as safety and effectiveness have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

SCO-58, 59, Sector-17D Chandigarh-160017
Other Info - LIM0002

Author Details

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FAQs

LIMBITROL TABLET is used to treat moderate to severe depression associated with moderate to severe anxiety.
LIMBITROL TABLET contains Amitriptyline and Chlordiazepoxide. Amitriptyline works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.
LIMBITROL TABLET may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.
Do not discontinue LIMBITROL TABLET without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking LIMBITROL TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking LIMBITROL TABLET.
Dry mouth could be a side-effect of LIMBITROL TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Constipation might occur as a side-effect of LIMBITROL TABLET. Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you experience severe constipation.
LIMBITROL TABLET may cause side effects like dizziness and tiredness in some people. Consult the doctor if the condition persists or if you experience severe dizziness or tiredness.
Painkillers should be taken with LIMBITROL TABLET only if advised by the doctor. However, opioid-based analgesics should not be taken with LIMBITROL TABLET as it may cause drowsiness and breathing problems. Always check with the doctor before taking painkillers or other medicines along with LIMBITROL TABLET.
LIMBITROL TABLET may cause suicidal thoughts/behaviour; therefore, monitor the person taking LIMBITROL TABLET for any changes in mood/behaviour and report to the doctor if you notice any unusual behaviour.
Eat a healthy diet and exercise regularly to manage weight gain associated with the use of LIMBITROL TABLET. Talk to the doctor if the increase in weight bothers you.
Store LIMBITROL TABLET at room temperature, protected from light and moisture. Keep it out of sight and reach of children.
Yes, LIMBITROL TABLET may cause sleepiness. Do not drive or operate machinery unless you know how the medicine affects you.
LIMBITROL TABLET may cause sexual problems like decreased sexual desire, inability to reach an orgasm and erectile dysfunction in men. Discuss with the doctor if you experience sexual problems during treatment with LIMBITROL TABLET.
No, do not drink alcohol while taking LIMBITROL TABLET. Consuming alcohol along with LIMBITROL TABLET could lead to increased drowsiness & dizziness and very serious side effects.
LIMBITROL TABLET may change the colour of urine to green or blue. It is generally harmless and resolves once the medicine is stopped. However, consult the doctor if you have any concerns regarding this.
LIMBITROL TABLET may start working within a week. However, it might take around 4 weeks to notice the full benefits of LIMBITROL TABLET. Continue taking LIMBITROL TABLET for the prescribed duration to treat your condition effectively.
The active ingredients of LIMBITROL TABLET are Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). It is used to treat moderate to severe depression associated with moderate to severe anxiety.
LIMBITROL TABLET can be taken with or without food as advised by the doctor. Swallow LIMBITROL TABLET as a whole with a glass of water; do not chew or crush it.
Yes, LIMBITROL TABLET is safe if taken in the dose and duration prescribed by the doctor. It should not be taken for longer durations as it may cause physical dependence.
Though LIMBITROL TABLET may help you sleep better by improving your mood, it should not be used for sleep-related issues. Talk to the doctor if you have sleep-related problems.
LIMBITROL TABLET may not be beneficial for heart health as it may cause QT prolongation (a condition that affects heart rhythm) in some people. Before starting treatment with LIMBITROL TABLET discuss you’re your doctor if you have heart rhythm problems.
Side effects of LIMBITROL TABLET include dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

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