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compositionComposition:LINEZOLID-600MG
prescriptionPrescription Medicine
Linosept 600 mg Injection 1's
Linosept 600 mg Injection 1's
Linosept 600 mg Injection 1's

Linosept-600 Injection is an antibiotic medication used to treat bacterial infections of the skin and soft tissues, lungs (pneumonia) and bloodstream infections. It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LINEZOLID-600MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Linosept-600 Injection

Linosept-600 Injection is used to treat bacterial infections of the lungs (pneumonia), skin and soft tissues. It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body.

Linosept-600 Injection contains Linezolid, which inhibits bacterial protein synthesis, thereby killing the bacteria.

You may experience common side effects, such as headache, a metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, pain at the injection site, and indigestion. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Do not take Linosept-600 Injection on your own, as it may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. Consult your doctor if you are pregnant or planning to become pregnant before taking Linosept-600 Injection.

Uses of Linosept-600 Injection

Linosept-600 Injection is used in the treatment of bacterial infections. The detailed uses of Linosept-600 Injection are as follows:

  • Pneumonia (Lung Infection): Linosept-600 Injection is effective in treating both community-acquired and hospital-acquired pneumonia caused by susceptible bacteria.
  • Skin and Skin Structure Infections: Linosept-600 Injection is used to treat mild to severe bacterial infections of the skin and its underlying tissues. It is also indicated for the treatment of diabetic foot infections without associated bone infections (osteomyelitis).
  • Antibiotic-Resistant Infections: Linosept-600 Injection is indicated for infections caused by the bacteria Enterococcus faecium that are resistant to vancomycin, including intra-abdominal infections, skin and soft tissue infections, urinary tract infections, and concurrent bacteremia (presence of bacteria in the bloodstream).

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Linosept-600 Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Key Benefits

For Pneumonia:

  • Cures pneumonia brought on by resistant gram-positive bacteria.
  • Beneficial for ventilator-associated pneumonia and pneumonia acquired in hospitals
  • Relieves the symptoms of infection, breathing and fever when other antibiotics are ineffective.
  • Ideal for people who don't react to or can't handle other antibiotics

For soft skin structures:

  • Beneficial for complex soft tissue and skin infections, such as cellulitis, abscesses, and wound infections
  • Ensures efficient infection control by having good penetration into soft tissues and skin.
  • Aids in lowering infection-related discomfort, redness, swelling, and pus production

For Vancomycin-resistant enterococcal infections

  • Beneficial for severe infections include bloodstream infections, intra-abdominal infections, and complex VRE-caused urinary tract infections
  • When other antibiotics are ineffective or poorly tolerated, it helps patients achieve better clinical results.

How Linosept-600 Injection Works

Linosept-600 Injection contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Linosept 600 mg Injection
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Eat fiber-rich foods like broccoli, cauliflower, leafy greens, and Brussels sprouts.
  • Limit sugar and refined carbs like avoid sugary drinks, white bread, and processed foods.
  • Choose lean protein sources like chicken, fish, and tofu.
  • Choose low-sugar fruits like berries, citrus fruits, and apples in moderation.
  • Maintain good hygiene and keep affected areas clean and dry.
  • Wear breathable clothing to reduce moisture.
  • Consider natural antifungal agents like coconut oil, tea tree oil, and garlic (consult a healthcare professional before use).

What if I have taken an overdose of Linosept-600 Injection

Linosept-600 Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose of Linosept-600 Injection may cause wheezing, chest tightness, seizures, swelling of the face, lips, tongue, or throat, and severe diarrhoea. Your doctor will initiate necessary measures when an overdose is suspected.

Drug Warnings

  • Do not take Linosept-600 Injection if you are allergic to any of its contents or if you are taking or have taken monoamine oxidase (MAO-antidepressants) inhibitors in the last 14 days.
  • Talk to your doctor if you have high blood pressure, an overactive thyroid, phaeochromocytoma (tumour of adrenal glands), carcinoid syndrome (tumours of the hormone system), manic depression, schizophrenia, confusion, or other mental problems.
  • Consult your doctor if you are pregnant before taking Linosept-600 Injection.
  • Linosept-600 Injection passes into breastmilk, so do not take Linosept-600 Injection if you are breastfeeding.
  • Linosept-600 Injection may cause dizziness and vision problems; therefore, exercise caution when driving and operating machinery.

Drug-Drug Interactions

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LinezolidMephentermine
Critical
LinezolidVortioxetine
Critical

Drug-Drug Interactions

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LinezolidMephentermine
Critical
How does the drug interact with Linosept 600 mg Injection:
Taking Linosept 600 mg Injection and Mephentermine together may cause high blood pressure.

How to manage the interaction:
Taking Mephentermine with Linosept 600 mg Injection is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LinezolidVortioxetine
Critical
How does the drug interact with Linosept 600 mg Injection:
Co-administration of Linosept 600 mg Injection with Vortioxetine can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Linosept 600 mg Injection with Vortioxetine can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.
LinezolidTapentadol
Critical
How does the drug interact with Linosept 600 mg Injection:
Using Tapentadol together with Linosept 600 mg Injection might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Tapentadol with Linosept 600 mg Injection is not recommended, consult a doctor before taking it. If you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea call a doctor right away. Do not stop using any medications without talking to a doctor.
LinezolidCarbamazepine
Critical
How does the drug interact with Linosept 600 mg Injection:
Using Carbamazepine with Linosept 600 mg Injection can cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Carbamazepine and Linosept 600 mg Injection together is not recommended, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
LinezolidMethylphenidate
Critical
How does the drug interact with Linosept 600 mg Injection:
Taking Linosept 600 mg Injection with Methylphenidate together may increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Linosept 600 mg Injection with Methylphenidate is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden and severe headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, contact a doctor immediately. You may use methylphenidate only after you have been off Linosept 600 mg Injection for at least 14 days. Do not discontinue any medications without consulting a doctor.
LinezolidNortriptyline
Critical
How does the drug interact with Linosept 600 mg Injection:
Coadministration of Nortriptyline with Linosept 600 mg Injection might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Nortriptyline with Linosept 600 mg Injection together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidOxcarbazepine
Critical
How does the drug interact with Linosept 600 mg Injection:
When Oxcarbazepine is taken with Linosept 600 mg Injection, it can increase the risk of serotonin syndrome(a condition when your body has too much of a chemical called serotonin), further leading to side effects.

How to manage the interaction:
Taking Oxcarbazepine with Linosept 600 mg Injection is not recommended, as it results in an interaction, it can be taken if advised by a doctor. However, if you experience symptoms such as confusion, hallucination (seeing or hearing things that do not exist), seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor’s advice.
LinezolidTramadol
Critical
How does the drug interact with Linosept 600 mg Injection:
Co-administration of Linosept 600 mg Injection with Tramadol can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Linosept 600 mg Injection with Tramadol is not recommended, consult a doctor before taking it. Consult a doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not stop using any medications without talking to a doctor.
LinezolidCaffeine
Critical
How does the drug interact with Linosept 600 mg Injection:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Caffeine with Linosept 600 mg Injection is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
LinezolidBuspirone
Critical
How does the drug interact with Linosept 600 mg Injection:
Combining Linosept 600 mg Injection with Buspirone can increase the risk of high blood pressure.

How to manage the interaction:
Taking Buspirone with Linosept 600 mg Injection is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eating changes:

  • Avoid foods like salami, smoked meats, red wine, beer, pickles, soy sauce, aged cheeses, and fermented foods.
  • Consume foods that are newly cooked rather than ones that are aged or preserved.
  • Eat a diet rich in fruits, vegetables, whole grains, and lean meats to stay balanced.

Physical activity:

  • As tolerated, engage in mild-to-moderate exercise, such as walking or gentle stretching.
  • Ensure adequate sleep to support the healing process after an infection.

Environment changes:

  • To reduce the risk of developing or worsening infections, stay in a clean, well-ventilated environment.
  • Avoid dusty or congested areas, particularly during treatment for severe diseases.
  • Keep your house and workplace clean and practice good hand hygiene.

Stress management:

  • To manage stress and blood pressure, engage in mindfulness, meditation, or deep breathing exercises.
  • To lessen mental stress, get emotional support from friends or family.

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

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Alcohol

Unsafe

Avoid consuming alcohol while taking Linosept-600 Injection as it may cause increased dizziness.

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Pregnancy

Consult your doctor

The safety of Linosept-600 Injection in pregnant women is not known. If you are pregnant, consult your doctor.

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Breast Feeding

Caution

If you are a breastfeeding mother, inform your doctor before receiving this medicine. Linosept-600 Injection passes into breastmilk and can cause diarrhoea and vomiting in infants; therefore, discontinue breastfeeding prior to and throughout the treatment.

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Driving

Caution

Linosept-600 Injection may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Long-term treatment with Linosept-600 Injection may worsen your liver condition if you have liver problems. Dose adjustment may be needed. Please inform your doctor before taking Linosept-600 Injection if you have liver impairment/liver disease or a history of liver conditions.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before receiving this injection.

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Children

Consult your doctor

Your doctor will weigh the benefits and potential risks before prescribing Linosept-600 Injection for your children based on age and the condition of the child.

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Heart

Caution

Linosept-600 Injection can be used in heart patients but requires caution due to potential blood pressure changes. Always inform your doctor about your heart condition and medications to avoid serious interactions.

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Geriatrics

Caution

Geriatric patients can receive Linosept-600 Injection, but it may be more prone to side effects like low blood cell counts or neuropathy. Regular monitoring and dose adjustments help ensure safe and effective treatment.

FAQs

Linosept-600 Injection belongs to the class of medicines called oxazolidinones, used to treat bacterial infections of the lungs (pneumonia) and skin. It is also used to treat infections which are resistant to other antibiotics.

Linosept-600 Injection works by stopping the growth of infection-causing bacteria. Thus, it treats the infection.

Diarrhoea might be a side-effect of Linosept-600 Injection. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain while on treatment with Linosept-600 Injection, inform your doctor. Do not take anti-diarrheal medicine on your own.

Linosept-600 Injection may cause oral or vaginal thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth/throat or vagina. Consult your doctor if the condition persists or worsens.

Linosept-600 Injection may affect certain laboratory test results such as blood tests, blood sugar tests, and liver and kidney function tests. Inform the lab technician that you are on treatment with Linosept-600 Injection.

Linosept-600 Injection may cause anaemia due to a decrease in the number of red blood cells. This could also cause unexplained bleeding or bruising. Consult your doctor if you experience unexplained bleeding or bruising.

Linosept-600 Injection may cause side effects, such as headache, a metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, pain at the injection site, and indigestion. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

27, RACE COURSE ROAD, BANGALORE-560 001, INDIA.
Other Info - LIN0080

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