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compositionComposition:BACLOFEN-10MG
prescription
Prescription Medicine
info
Liofen XL Capsule 10's
Liofen XL Capsule 10's
Liofen XL Capsule 10's
Liofen XL Capsule 10's
Liofen XL Capsule 10's

Liofen XL Capsule is used to reduce and relieve muscle spasms (muscles with too tight or stiff). It contains Baclofen, which works on the spinal cord and brain, thereby helping in maintaining muscle strength and relieving muscle spasms or stiffness. Thus, it reduces muscle spasm in conditions like multiple sclerosis (which affects the brain and spinal cord), stroke, cerebral palsy (which affects movement and posture), spinal cord problems, and other nerve-related conditions. In some cases, you may experience certain common side effects such as feeling sleepy or tired, drowsiness, nausea, headache, weakness, and dry mouth. Before you start using Liofen XL Capsule , tell your doctor if you are allergic to anything in Liofen XL Capsule , if you are pregnant or breastfeeding, and about any other medicines or health issues you have.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BACLOFEN-10MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Liofen XL Capsule

Liofen XL Capsule is an oral medication prescribed to help relax stiff or spasming muscles. It is primarily used to treat muscle rigidity, cramping, and tightness caused by conditions like multiple sclerosis or spinal cord injuries. By easing these symptoms, it helps improve your physical comfort and ability to move.

For the best results, you should take Liofen XL Capsule consistently at the same times every day as directed by your doctor. You can take this medicine with or without food, but taking it with a glass of milk or a meal can help prevent an upset stomach. Combining your treatment with daily physical therapy and gentle stretching exercises can also greatly support your progress.

While taking Liofen XL Capsule , you may experience some common side effects such as drowsiness, dizziness, or mild nausea. If you experience more serious issues, such as severe confusion, muscle weakness, or breathing difficulties, you must contact your doctor immediately.

Before you begin taking Liofen XL Capsule , talk to your doctor if you have kidney disease, epilepsy, or a history of strokes. Do not take this if you have had a severe allergic reaction to this medication or any of its ingredients in the past.

This medicine can interact with alcohol, smoking, and other drugs that cause drowsiness, making you feel excessively sleepy or lightheaded. If you are pregnant, planning to breastfeed, or are an elderly individual, consult your doctor or pharmacist to discuss whether this treatment is safe for you.
 

Uses of Liofen XL Capsule

Liofen XL Capsule is used to help relax stiff or spasming muscles. The detailed uses of Liofen XL Capsule are as follows:

  • Muscle spasms from multiple sclerosis: Liofen XL Capsule helps reduce severe muscle stiffness, pain, and involuntary spasms, making it easier to manage daily activities.
  • Spinal cord injuries: It works to relax tight muscles and relieve severe cramping resulting from traumatic spinal cord damage.
  • Spinal cord diseases: This medicine eases muscle rigidity and tension caused by non-traumatic spinal cord disorders.

Key Benefits

Liofen XL Capsule brings real-world relief by helping your body move more freely and comfortably. By targeting the source of muscle tension, it provides several key benefits:

  • Improved mobility: It relaxes stiff muscles so you can walk, bend, and perform daily tasks with less pain and effort.
  • Better sleep: Easing painful nighttime muscle cramps allows you to get more restful, uninterrupted sleep.
  • Enhanced physical therapy: With less muscle tightness, you can participate more effectively in rehabilitation and stretching exercises.
Side effects of Liofen XL Capsule
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Do pelvic floor exercises (Kegel exercises) to gain more control over urinary sphincters (muscles used to control flow of urine out of the bladder).
  • Drink fluids only at certain times to control when you will urinate.
  • If you feel frequent urge to urinate or have problems starting to urinate or if your urine stream is weak or starts and stops, or feel pain in your genitals, lower abdomen or lower back, consult your doctor.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Directions for Use

Always take this medicine exactly as your healthcare provider has instructed. Follow these steps for safe use:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet unless your doctor specifically tells you to do so.
  • If you are taking the liquid form, measure each dose carefully using the marked measuring syringe or cup provided by your pharmacist, rather than a standard kitchen spoon.
    Take your doses at regular intervals to keep a steady amount of the medicine in your body.Do not stop taking this medication suddenly, as doing so can cause serious withdrawal symptoms. Talk to your doctor if you need to stop your treatment.

 

How Liofen XL Capsule Works

Liofen XL Capsule works by acting directly on the nerves in your spinal cord that control muscle movement. When these nerves become overactive, they cause muscles to tighten and spasm. The active ingredient in Liofen XL Capsule mimics a natural chemical messenger in your nervous system that blocks these overactive signals. By calming the nerve pathways, it allows your muscles to relax and reduces painful stiffness.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Liofen XL Capsule as it may increase drowsiness.

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Pregnancy

Consult your doctor

Avoid taking Liofen XL Capsule if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Liofen XL Capsule ; your doctor will decide whether Liofen XL Capsule can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Liofen XL Capsule causes sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Liofen XL Capsule should be given with caution in children below 16 years, as limited data is available on its safety and effectiveness. Liofen XL Capsule is not recommended for children who weigh below 33 kg.

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Heart

Caution

Exercise caution before using Liofen XL Capsule in case of heart problems. Please consult your doctor if you have any concerns.

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Geriatrics

Caution

Exercise caution before using Liofen XL Capsule in case of heart problems. Please consult your doctor if you have any concerns.

What if I have taken an overdose of Liofen XL Capsule

Do not take more than the prescribed dose of Liofen XL Capsule as it may cause serious adverse effects such as dizziness, drowsiness, seizures (fits), excess sleepiness, shallow breathing, trouble focusing on objects, loss of consciousness, or muscle weakness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day, as dehydration can trigger or worsen muscle spasms.
  • Do gentle stretches: Perform light, doctor-approved stretching exercises daily to maintain joint flexibility and prevent muscles from shortening.
  • Move carefully: Stand up slowly from a sitting or lying position to prevent dizziness and reduce the risk of falling.
  • Avoid sedating substances: Avoid drinking alcohol, as it can dangerously increase the drowsy effects of your medicine.

Have a query?

How Soon It Starts Working

  • The time required for Liofen XL Capsule to start to work: The time required for Liofen XL Capsule to start to work is 2 to 3 hours after administration.
  • The time for which the effects of Liofen XL Capsule last: The effect of Liofen XL Capsule lasts for 7 to 12 hours.

What if you forget to take Liofen XL Capsule

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time. Do not take a double dose to make up for the missed one.

Storage

• Store Liofen XL Capsule tablets and liquid at room temperature between 20°C to 25°C (68°F to 77°F). • Keep the medicine in its original container, tightly closed, to protect it from direct light and moisture.

Drug Warnings

  • Never stop taking this medicine suddenly: Stopping abruptly can cause dangerous withdrawal symptoms, including high fever, confusion, hallucinations, and severe muscle stiffness. Always talk to your doctor to create a safe plan for gradually decreasing your dose.
  • Avoid driving or operating machinery: This medicine can make you very sleepy and slow your reaction times. Do not drive or do dangerous tasks until you are sure you can perform them safely.
  • Inspect liquid solutions before use: If you are taking the liquid form, check that the solution is clear and has no floating particles before each use.
  • Be cautious with other medications: Always check with your pharmacist before starting any new over-the-counter allergy, cold, or sleep medications, as these can increase drowsiness.
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • Central nervous system depressants: Taking Liofen XL Capsule with sleep medicines, opioid pain relievers, anxiety medications, or other muscle relaxants can cause extreme drowsiness and dangerous breathing difficulties.
  • Blood pressure medications: Combining this medicine with blood pressure drugs may increase the risk of low blood pressure, causing dizziness when standing.

 

Drug-Food Interactions

  • Alcohol: Drinking alcohol while taking this medicine can cause severe drowsiness, dizziness, and increase the risk of serious side effects.

 

Drug-Disease Interactions

  • Kidney disease: Since your kidneys clear this medicine from your body, having kidney disease can cause the drug to build up, leading to toxicity and increased side effects.
  • Epilepsy: This medicine may increase the frequency of seizures in people with a history of epilepsy.
     
BaclofenBuprenorphine
Severe
BaclofenRemifentanil
Severe

Drug-Drug Interactions

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BaclofenBuprenorphine
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Buprenorphine with Liofen XL Capsule can increase the risk of side effects.

How to manage the interaction:
Co-administration of Buprenorphine alongside Liofen XL Capsule can result in an interaction. However, it can be taken if a doctor has advised it. If you experience shortness of breath, chest discomfort, dizziness, or palpitations consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BaclofenRemifentanil
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Liofen XL Capsule can enhance the sedative effects of Remifentanil on the central nervous system which can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Co-administration of Liofen XL Capsule with Remifentanil can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend other options that won't cause any problems. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
BaclofenAlfentanil
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Liofen XL Capsule with Alfentanil can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Liofen XL Capsule and Alfentanil, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like dizziness, trouble breathing, drowsiness, or palpitations, let the doctor know. Do not stop using any medications without a doctor's advice.
BaclofenMorphine
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Liofen XL Capsule with Morphine may increase the risk or severity of side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Liofen XL Capsule with Morphine together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you notice any sudden dizziness, lightheadedness, severe headache, shortness of breath, chest pain or tightness, or weakness. Do not stop using any medications without consulting a doctor.
BaclofenEsketamine
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Liofen XL Capsule with Esketamine may increase the risk or severity of adverse effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Liofen XL Capsule can be used with Esketamine if prescribed by the doctor. Consult a doctor if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, and reaction speed. Do not stop any medication without doctor's consultation.
BaclofenPethidine
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Liofen XL Capsule can enhance the sedative effects of Meperidine on the central nervous system which can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Pethidine with Liofen XL Capsule together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
BaclofenNalbuphine
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Liofen XL Capsule can enhance the effects of Nalbuphine, which depresses the central nervous system and can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Liofen XL Capsule and Nalbuphine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
BaclofenPotassium hydrogencarbonate
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Liofen XL Capsule may decrease the excretion rate of Potassium hydrogencarbonate which could result in a higher serum level.

How to manage the interaction:
Although there is an interaction, Liofen XL Capsule can be used with Potassium hydrogencarbonate if prescribed by the doctor. Regular monitoring of serum potassium levels is advised.
BaclofenPentazocine
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Liofen XL Capsule can enhance the sedative effects of Pentazocine on the central nervous system which can lead to side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Liofen XL Capsule, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
BaclofenHydrocodone
Severe
How does the drug interact with Liofen XL Capsule:
Co-administration of Liofen XL Capsule with Hydrocodone may increase sedation and respiratory distress (fluid collects in the air sacs of the lungs)

How to manage the interaction:
Although there is an interaction, Liofen XL Capsule can be used with Hydrocodone if prescribed by the doctor. Co-administration of these medications may cause dizziness, drowsiness, difficulty in concentrating, and impaired judgment. Do not stop any medication without doctor's consultation.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[SKELETAL MUSCLE RELAXANTS]

FAQs

Liofen XL Capsule is used to reduce and relieve excessive muscle stiffness or spasms associated with conditions like cerebral palsy, multiple sclerosis, stroke, spinal cord disorders, and other nervous system diseases.

Liofen XL Capsule works on the centres of the spinal cord and brain, thereby helping in maintaining muscle strength and relieving muscle spasms or stiffness.

Liofen XL Capsule causes sleepiness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel sleepy or drowsy.

Dry mouth could be a side-effect of Liofen XL Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevent drying of the mouth.

Do not use Liofen XL Capsule at a time when muscle tone is required for safe balance and movement during certain activities. In some conditions, it may be dangerous for you to have low or reduced muscle tone. Please do not drink alcohol with Liofen XL Capsule as it can cause side effects. Avoid driving or performing hazardous tasks until you know how Liofen XL Capsule will affect you.

Liofen XL Capsule may reduce anxiety but not depression levels. However, it is not intended for treating anxiety.

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

While specific dosing instructions will vary depending on your needs and medical history, always follow your doctor's prescribed dosage and timing for taking these medications.

To avoid potential interactions and minimise side effects, before using this medication, you should inform your doctor about your medical history, including any ongoing medicines.

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Taking more than the recommended dosage does not provide additional benefits and can increase the risk of adverse effects. Take it only as advised by the doctor.

Liofen XL Capsule does not affect any method of contraception, including combined tablets or emergency contraception. However, if Liofen XL Capsule makes you sick (vomit) or causes severe diarrhoea for more than 24 hours, your contraceptive tablets may not be effective in preventing pregnancy. Check the pill packet to see what to do.

Alcohol can increase the drowsy (sedative) effects of Liofen XL Capsule pills, making you extremely tired. It is advisable to avoid drinking alcohol when taking Liofen XL Capsule until you know how the medication affects you.

No, you should never stop taking Liofen XL Capsule suddenly. Stopping it abruptly can cause serious withdrawal symptoms, such as hallucinations, high fever, and severe muscle rebound. Talk to your doctor about how to safely and gradually decrease your dose.

Yes, drowsiness and weakness are very common side effects of Liofen XL Capsule , especially when you first start taking it. Avoid driving or operating machinery until you know how this medicine affects you, and talk to your doctor if the sleepiness does not improve.

No, you should avoid alcohol while taking this medicine. Alcohol can dangerously increase the drowsy and dizzy effects of Liofen XL Capsule , making tasks like walking or driving unsafe. Talk to your doctor if you find it difficult to avoid alcohol.

Some people may feel relief from muscle tightness within a few hours of taking their dose, but for others, it may take several days of consistent use to notice a significant difference. Talk to your doctor if your symptoms do not improve after a few weeks.

Yes, you can take Liofen XL Capsule with or without food. If taking it on an empty stomach makes you feel nauseated or gives you an upset stomach, try taking it with a meal or a glass of milk. Talk to your doctor or pharmacist if stomach upset continues.

Liofen XL Capsule should only be used during pregnancy if your doctor determines that the benefits clearly outweigh the risks to your baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine.

Liofen XL Capsule is cleared from your body by your kidneys. If you have pre-existing kidney disease, the medicine can build up in your body and cause severe side effects. Talk to your doctor so they can monitor your kidney health and adjust your dose if necessary.

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and take your next dose at the regular time. Do not take two doses at once to make up for a missed dose. Talk to your doctor or pharmacist if you have questions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - LIO0068

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