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compositionComposition:PARACETAMOL-300MG
prescriptionPrescription Medicine
Lofev IV Injection 100 ml

Lofev IV Injection is an antipyretic and analgesic medicine used in the treatment of mild to moderate pain and fever. This medicine contains paracetamol which works by inhibiting the release of chemical messengers called prostaglandins that cause pain and inflammation. Some of the common side effects include constipation, nausea, and vomiting, and injection site reactions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

PARACETAMOL-300MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lofev IV Injection

Lofev IV Injection is used to relieve mild to moderate pain and to treat fever. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Fever occurs when the body's temperature goes above the average body temperature (98.6°F or 37°C).

Lofev IV Injection works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, reducing pain. Additionally, Lofev IV Injection affects an area of the brain that regulates body temperature, known as the hypothalamic heat-regulating centre, which reduces fever.

Not everyone who is taking Lofev IV Injection will get these side effects. Common side effects of Lofev IV Injection include constipation, nausea, and vomiting. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Lofev IV Injection is a parenteral preparation. A healthcare professional will administer it in a hospital. Do not self-administer this medication.

Please tell your doctor if you are allergic to any of the components of Lofev IV Injection . Let your doctor know if you use any other painkillers before starting this medicine. Inform your doctor if you have liver or kidney diseases, malnutrition, dehydration, and a history of alcoholism before starting Lofev IV Injection . It is essential to let your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother. It is not recommended to consume alcohol while using Lofev IV Injection .

Uses of Lofev IV Injection

Lofev IV Injection is used in the treatment of Pain and Fever. The detailed uses of Lofev IV Injection are as follows:

  • Pain Relief: Lofev IV Injection is widely used to alleviate moderate to severe pain, including headaches, muscle pain, and joint discomfort.
  • Fever Reduction: Lofev IV Injection is effective in reducing fever, making it helpful in managing illnesses where fever is a common symptom, such as infections.
  • Post-Operative Care: Lofev IV Injection is frequently administered in hospital settings to manage pain following surgical procedures.
  • Treatment of Inflammation: Lofev IV Injection anti-inflammatory effects aid in relieving symptoms caused by inflammatory conditions, providing overall comfort and relief.

Key Benefits

  • Lofev IV Injection contains 'Paracetamol,' which is an analgesic (relieves pain) and an antipyretic (reduces fever).
  • This process reduces the mild to moderate pain and inflammation at the injured or damaged site.
  • Lofev IV Injection also affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thus, it reduces fever.
Side effects of Lofev IV Injection 100 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of Lofev IV Injection to ensure its safe and effective use.
  • Lofev IV Injection will be administered by a healthcare professional in a hospital.
  • Do not self-administer this medication.

How Lofev IV Injection Works

Lofev IV Injection contains 'Paracetamol,' which prevents the formation of chemical messengers called prostaglandins, which cause pain and swelling at the injury sites. This process reduces the mild to moderate pain and inflammation at the injured or damaged site. Lofev IV Injection also affects an area of the brain that regulates body temperature known as the hypothalaat-regulating centre. Thus, it reduces fever.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Lofev IV Injection . Alcohol intake, along with Lofev IV Injection may cause increased liver damage.

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Pregnancy

Consult your doctor

Please consult your doctor before taking Lofev IV Injection if you are a pregnant.

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Breast Feeding

Consult your doctor

Lofev IV Injection should be used during breastfeeding only when suggested by a doctor.

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Driving

Safe if prescribed

Lofev IV Injection does not usually affect your ability to drive.

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Liver

Consult your doctor

Please consult your doctor since Lofev IV Injection should be used with caution in patients with liver impairment/liver disease.

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Kidney

Consult your doctor

Please consult your doctor since Lofev IV Injection should be used with caution in patients with kidney impairment/kidney disease.

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Children

Caution

Lofev IV Injection should be given to children only when prescribed by a doctor

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Heart

Safe if prescribed

Lofev IV Injection is generally considered safe for heart patients when used at recommended doses. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Lofev IV Injection is considered safe for elderly patients when administered at recommended doses; however, liver function and total daily dosage should be monitored to prevent toxicity.

What if I have taken an overdose of Lofev IV Injection

Since Lofev IV Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Diet & Lifestyle Advise

  • Performing yoga may help in improving overall flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy; apply a cold or hot compress on the joints for 15-20minutes regularly.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Have a query?

How Soon It Starts Working

The time required for Lofev IV Injection to start to work: Lofev IV Injection shows its action within 1 hour of administration. The time for which the effects of Lofev IV Injection last: Lofev IV Injection effect last for 4 to 6 hours.

What if you forget to take Lofev IV Injection

As this medicine is administered by a healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid taking Lofev IV Injection if allergic to it.
  • Lofev IV Injection is not recommended for children below 6 years of age as the safety and efficacy are not established.
  • If you are pregnant or breastfeeding, please consult a physician before using Lofev IV Injection .
  • Avoid alcohol consumption with Lofev IV Injection as it may increase the risk of liver damage.
  • If you have an impaired nutritional state caused by anorexia (eating disorder), wrong nutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Lofev IV Injection .
  • Avoid taking more than the recommended doses, as it may increase the risk of serious liver damage.
  • If you have a high fever or signs of infection after using Lofev IV Injection for more than 3 days or if pain persists after using Lofev IV Injection for more than 5 days, please consult a physician.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Lofev IV Injection may interact with gout medicines (probenecid), anti-inflammatory drugs (salicylamide), and anticoagulants (warfarin, acenocoumarol).

Drug-Food Interaction: Avoiding alcohol is advised while being treated with Lofev IV Injection .

Drug-Disease Interaction: Before using Lofev IV Injection , let your doctor know if you have any liver or kidney diseases, malnutrition, dehydration, and a history of alcoholism.

ParacetamolOxazepam
Severe
ParacetamolKetamine
Severe

Drug-Drug Interactions

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ParacetamolOxazepam
Severe
How does the drug interact with Lofev IV Injection 100 ml:
Co-administration of Lofev IV Injection 100 ml may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Lofev IV Injection 100 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetamine
Severe
How does the drug interact with Lofev IV Injection 100 ml:
Co-administration of ketamine and Lofev IV Injection 100 ml may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Lofev IV Injection 100 ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolKetoconazole
Severe
How does the drug interact with Lofev IV Injection 100 ml:
Co-administration of Lofev IV Injection 100 ml and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Lofev IV Injection 100 ml and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Lofev IV Injection 100 ml:
Co-administration of Lofev IV Injection 100 ml and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Lofev IV Injection 100 ml and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Lofev IV Injection 100 ml:
Co-administration of Lofev IV Injection 100 ml and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Lofev IV Injection 100 ml and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Lofev IV Injection 100 ml:
Co-administration of Mipomersen with Lofev IV Injection 100 ml may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Lofev IV Injection 100 ml and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Lofev IV Injection 100 ml:
Co-administration of Teriflunomide with Lofev IV Injection 100 ml may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Lofev IV Injection 100 ml with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Lofev IV Injection 100 ml:
Co-administration of Lomitapide and Lofev IV Injection 100 ml may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Lofev IV Injection 100 ml and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESIC AND ANTIPYRETIC AGENT]

FAQs

Lofev IV Injection is used to relieve mild to moderate pain and to treat fever. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Fever occurs when the body's temperature exceeds the average (98.6°F or 37°C).

Lofev IV Injection works by blocking the effect of chemical messengers (prostaglandins), thereby reducing fever, pain, stiffness, swelling, and inflammation.

It is not advised to take Lofev IV Injection on your own. You should use Lofev IV Injection only if a healthcare professional prescribes it.

Lofev IV Injection is to be cautiously used in case of any allergic reactions to other pain killers. Let your doctor know your medical history before starting Lofev IV Injection .

Though Lofev IV Injection is usually safe to use, it may very rarely cause serious skin reactions like generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN). Please discontinue the usage of Lofev IV Injection if you notice any skin rash and consult your doctor immediately.

Disclaimer

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Author Details

Veda MaddalaDoctor badge

Written By

  • Veda Maddala

    M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

  • Santoshini Reddy G

    M Pharmacy

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, India.
Other Info - LOF0029
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