Do not use KETAMINE if you are allergic to any of its components if you are suffering from any condition in which an increase in blood pressure may be harmful to you, if you have been pregnant, and during your pregnancy, you have suffered from a condition called eclampsia or pre-eclampsia which causes an increase in your blood pressure, if you have/had stroke, serious head or brain injury, or severe heart disease. Inform the doctor if you have/had mental health problems, chest infection, breathing problems, liver problems, glaucoma, porphyria, seizures, thyroid disorder, head injury or abnormal growth in the brain, if you drink large amounts of alcohol or if you have a history of drug abuse or addiction. Consult the doctor if you are pregnant or breastfeeding. Let your doctor know if you are taking any prescription/non-prescription medicines or herbal supplements.

Drug-Drug Interactions: Inform the doctor if you are taking antipsychotics (aripiprazole), sedatives (zolpidem), benzodiazepines (lorazepam, clonazepam, diazepam, midazolam), antihistamines (diphenhydramine), opioids (hydromorphone), antidepressants (cyclobenzaprine, escitalopram, fluoxetine), or antiepileptics (lamotrigine, pregabalin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have high blood pressure, eclampsia (seizures during pregnancy or shortly after giving birth), pre-eclampsia (high blood pressure during pregnancy), stroke, serious head or brain injury, or severe heart disease.