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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Loftair 110/50mcg Capsule is used to treat chronic obstructive pulmonary disease (COPD). It helps relax and widen the airways, making it easier for air to enter and exit the lungs. It also decreases the secretions in the airways. In some cases, this medicine may cause side effects such as sinus inflammation, runny/stuffy nose, headache, dizziness, and stomach upset.

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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Loftair 110/50mcg Capsule

Loftair 110/50mcg Capsule is used for long-term, maintenance treatment of chronic obstructive pulmonary disease (COPD).

Loftair 110/50mcg Capsule is a combination of two medicines: Indacaterol and Glycopyrrolate. Indacaterol relaxes and widens the airways, making it easier for air to enter and exit the lungs. Glycopyrrolate decreases the secretions in the airways. Together, Loftair 110/50mcg Capsule provides relief from COPD.

Use Loftair 110/50mcg Capsule strictly as prescribed by your doctor or as instructed on the label. In some cases, Loftair 110/50mcg Capsule may cause common side effects, such as upper respiratory tract infections, sinus inflammation, runny/stuffy nose, headache, dizziness, and stomach upset. Please talk to your doctor if you experience these side effects persistently.

Do not stop using Loftair 110/50mcg Capsule on your own, as this may worsen symptoms. Consult your doctor if you are pregnant or breastfeeding. Loftair 110/50mcg Capsule is not recommended for children under 18 years old, as safety and effectiveness have not been established.

Uses of Loftair 110/50mcg Capsule

Loftair 110/50mcg Capsule is used to treat chronic obstructive pulmonary disease (COPD). The detailed uses of Loftair 110/50mcg Capsule are as follows:

  • Long-term Maintenance Treatment of COPD: Daily use of Loftair 110/50mcg Capsule helps improve airflow and make breathing easier for patients with COPD.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Place the mouthpiece between your lips, press the inhaler, and breathe in slowly. Hold your breath for a few seconds, then slowly breathe out.
  • Rinse your mouth with water and spit it out to avoid fungal infections in the mouth and throat.

Medicinal Benefits

  • Loftair 110/50mcg Capsule is used for long-term maintenance treatment of chronic obstructive pulmonary disease (COPD).
  • It helps improve airflow and makes breathing easier in patients with COPD.
  • It effectively manages persistent cough, wheezing, and mucus buildup.
  • It prevents bronchial constriction and reduces shortness of breath.
  • Regular use of Loftair 110/50mcg Capsule helps reduce the frequency and severity of flare-ups in stable COPD patients.

How Loftair 110/50mcg Capsule Works

Loftair 110/50mcg Capsule contains two long-acting bronchodilators: Indacaterol and Glycopyrrolate. • Indacaterol: It helps relax and widen the airways, making it easier for air to enter and exit the lungs. • Glycopyrrolate: It helps decrease the secretions in the airways. • Together, they provide relief for patients with COPD.

Storage

• Store in a cool and dry place away from sunlight.• Keep Loftair 110/50mcg Capsule out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Throat pain can worsen if there is no proper rest for your throat.
  • Drink plenty of warm fluids and frequently gargle with salt water.
  • Humidify the surrounding air using a humidifier, as dry air may increase dryness and throat pain.
  • Consider taking lozenges or hard candy throat pain relievers, which give a soothing effect.
  • Take enough rest and stay in warm places to reduce pain quickly.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Rest and get enough sleep, and try to give your voice a break.
  • Drink fluids to stay hydrated and to keep your throat moist; avoid caffeine and alcohol.
  • Soothe your throat with warm drinks like tea, broth, or warm water with honey.
  • Gargle with salt water to ease throat pain.
  • Use a humidifier or steam to moisten dry air.
  • Lozenges or hard candy can help soothe a sore throat.
  • Avoid smoke and harsh cleaning products that can irritate your throat.
  • Stay at home until you are feeling better to avoid spreading germs.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Loftair 110/50mcg Capsule

Use Loftair 110/50mcg Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it may cause adverse effects. If you experience any unusual symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Before taking Loftair 110/50mcg Capsule , inform your doctor if you:

  • are allergic to any of its contents.
  • are taking any medications for lung diseases.
  • are pregnant or breastfeeding.
  • have a history of asthma, seizures, diabetes, or glaucoma.
  • have thyroid, heart, kidney, or liver problems.
  • have difficulty in passing urine, high blood pressure, or gastrointestinal obstruction.

Drug-Drug Interactions

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Severe

Drug-Drug Interactions

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How does the drug interact with Loftair 110/50mcg Capsule:
Coadministration of levodopa with Loftair 110/50mcg Capsule can significantly decrease the blood levels of levodopa.

How to manage the interaction:
Although using Loftair 110/50mcg Capsule and levodopa together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Loftair 110/50mcg Capsule:
Taking Pramlintide with Loftair 110/50mcg Capsule can cause slow stomach emptying or slow the intestinal absorption of nutrients.

How to manage the interaction:
Although using Pramlintide and Loftair 110/50mcg Capsule together can lead to an interaction, it can be taken if advised by your doctor.
How does the drug interact with Loftair 110/50mcg Capsule:
Co-administration of Digoxin and Loftair 110/50mcg Capsule may increase the serum concentration of Digoxin and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Digoxin and Loftair 110/50mcg Capsule, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Loftair 110/50mcg Capsule:
The use of Potassium chloride and Loftair 110/50mcg Capsule can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Using Potassium chloride and Loftair 110/50mcg Capsule together can lead to an interaction, however, it can be taken if advised by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Loftair 110/50mcg Capsule:
The combined use of secretin and Loftair 110/50mcg Capsule can inhibit gastric acid secretion.

How to manage the interaction:
Although using secretin and Loftair 110/50mcg Capsule together can lead to an interaction, it can be taken if advised by your doctor.
IndacaterolCarvedilol
Severe
How does the drug interact with Loftair 110/50mcg Capsule:
Taking Carvedilol and Loftair 110/50mcg Capsule may reduce the treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Loftair 110/50mcg Capsule and Carvedilol, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
IndacaterolLabetalol
Severe
How does the drug interact with Loftair 110/50mcg Capsule:
Combining Labetalol and Loftair 110/50mcg Capsule could decrease the medical benefits of both medications.

How to manage the interaction:
Although taking Labetalol and Loftair 110/50mcg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. Do not forget to inform a doctor, if you have severe chronic obstructive pulmonary disease (COPD) or a history of asthma, as Labetalol is often not advised in these patients. Do not discontinue any medications without a doctor's advice.
IndacaterolPropranolol
Severe
How does the drug interact with Loftair 110/50mcg Capsule:
Using propranolol together with Loftair 110/50mcg Capsule may reduce the benefits of both medications, since they have opposing effects in the body. In addition, propranolol can cause breathing problems.

How to manage the interaction:
Although taking Propranolol together with Loftair 110/50mcg Capsule can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Diet and Nutrition:

  • Eat more high-protein foods, such as pulses, eggs, milk, curd, and lean meat, to help keep your breathing muscles strong.
  • Choose fresh fruits and vegetables for antioxidant and immunity support.
  • Have small, frequent meals to avoid breathlessness while eating.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice, as they may worsen symptoms.

Preventive lifestyle measures:

  • Quit smoking completely; it is the most important step to slow disease progression.
  • Avoid dust, smoke, air pollution, and strong fumes as much as possible.
  • Ensure adequate rest and sleep.

Physical activity and breathing care:

  • Try meditation, deep breathing, regular exercise, and progressive muscle relaxation techniques to relieve stress and reduce your risk of an attack.
  • Engage in regular, mild physical activity such as walking, as tolerated.

Monitoring parameters:

  • Monitor for any changes in breathlessness, cough, sputum colour or quantity, and how often you have flare-ups.
  • Keep track of oxygen saturation if advised by your doctor, along with regular and correct use of inhalers and response to treatment.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR

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Alcohol

Caution

You are advised not to consume alcohol while taking Loftair 110/50mcg Capsule as it might cause increased dizziness.

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Pregnancy

Caution

Loftair 110/50mcg Capsule belongs to pregnancy category C. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Loftair 110/50mcg Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Loftair 110/50mcg Capsule may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Loftair 110/50mcg Capsule is not recommended for children below 18 years, as safety and effectiveness have not been established.

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Heart

Caution

Loftair 110/50mcg Capsule should be used with caution in patients with heart disease due to increased risk of side effects. Therefore, please consult your doctor before using Loftair 110/50mcg Capsule .

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Geriatrics

Consult your doctor

Loftair 110/50mcg Capsule should be used in elderly patients only when prescribed by a doctor. If you have any concerns about using Loftair 110/50mcg Capsule in older adults, please consult your doctor.

FAQs

Loftair 110/50mcg Capsule is used for long-term, maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD).

Loftair 110/50mcg Capsule contains Indacaterol and Glycopyrrolate. Indacaterol relaxes and widens the openings in the airways, making it easier for the air to get in and out of the lungs. Glycopyrrolate decreases the secretions in the airways. Together, Loftair 110/50mcg Capsule provides relief for those with COPD.

Loftair 110/50mcg Capsule is used for the maintenance treatment for COPD. It does not treat a sudden attack of wheezing or breathlessness. Use a rescue inhaler to treat sudden breathing problems.

Dry mouth may be a side effect of Loftair 110/50mcg Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum or candy may help stimulate saliva and thereby prevent mouth dryness.

Do not stop taking Loftair 110/50mcg Capsule on your own, as it might cause worsening of symptoms. To treat your condition effectually, continue taking Loftair 110/50mcg Capsule for as long as your doctor has prescribed it. Talk to your doctor if your breathing problems, wheezing, or cough do not improve or worsen.

No, Loftair 110/50mcg Capsule is not indicated for the treatment of asthma, as the safety and effectiveness of Loftair 110/50mcg Capsule in patients with asthma have not been established. Consult your doctor if you have asthma.

The safety of Loftair 110/50mcg Capsule during pregnancy or breastfeeding is not well established. It should only be used if prescribed by a doctor. Your doctor will evaluate whether the benefits outweigh the risks in your specific case.

Loftair 110/50mcg Capsule is not recommended for children under 18 years, as its safety and effectiveness have not been established for this age group.

If you are allergic to milk proteins, you should be cautious when taking Loftair 110/50mcg Capsule , as it may contain milk proteins or lactose (milk sugar). Always make sure that your doctor is aware of your allergies so they can determine whether this medication is safe for you.

Some people may experience common side effects such as a sore throat, sinus inflammation, a runny or blocked nose, headache, dizziness, or an upset stomach. These are usually mild and go away on their own without requiring medical attention. If these side effects persist or become bothersome, contact your doctor for further advice and management.

Store Loftair 110/50mcg Capsule at room temperature, away from heat, moisture, and direct sunlight. Keep it in a safe place, out of the reach of children. Do not freeze the medication.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - LOF0048

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