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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Lopid 600 Tablet is used to treat raised or increased levels of cholesterol or fat/oils. It contains Gemfibrozil, which increases the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, it decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol). It may cause side effects such as vomiting, abdominal pain, nausea, flatulence, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

GEMFIBROZIL-600MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lopid 600 Tablet

Lopid 600 Tablet belongs to a group of medications called 'fibric acid derivatives' or 'fibrates' primarily used to treat raised or increased levels of cholesterol or fat/oils. Hyperlipidaemia or hypertriglyceridemia is a condition in which there is a high level of low-density lipoproteins (LDL) or bad cholesterol and a decreased level of high-density lipoprotein (HDL) or good cholesterol. Increased bad cholesterol level leads to a high risk of heart attack and stroke in the future, especially for heart disease patients.

Lopid 600 Tablet contains 'Gemfibrozil', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Lopid 600 Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Take Lopid 600 Tablet as prescribed by your doctor. You are advised to take Lopid 600 Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience vomiting, abdominal pain, nausea, flatulence, and diarrhoea. Most of these side effects of Lopid 600 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

It is important to have your cholesterol and triglyceride levels (lipid profile) checked regularly. Before starting Lopid 600 Tablet , please inform your doctor if you have any allergies, severe kidney disease, severe liver disease, or gallbladder disease. Inform your doctor if you have ever had gallstones, cataracts (clouding in the eye lens that causes decreased vision) and heart disease. Inform your doctor if you have taken other cholesterol medicines with this Lopid 600 Tablet . Immediately contact your doctor if you are pregnant and breastfeeding.

Uses of Lopid 600 Tablet

Treatment of High cholesterol levels.

Directions for Use

Take Lopid 600 Tablet as prescribed by your doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Lopid 600 Tablet belongs to a group of medications called 'fibric acid derivatives' or 'fibrates' primarily used to treat raised or increased levels of cholesterol or fat/oils. Lopid 600 Tablet works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Lopid 600 Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

How Lopid 600 Tablet Works

Lopid 600 Tablet contains 'Gemfibrozil', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Lopid 600 Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Storage

Store in a cool and dry place away from sunlight
Side effects of Lopid 600 Tablet
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Lopid 600 Tablet

Do not take more than the prescribed dose of Lopid 600 Tablet as it may cause overdose. The symptoms of overdose include stomach cramps, diarrhoea, increased enzymes in the body (signs of this are muscle pain, tenderness, weakness, swelling, urine becomes dark in colour), feeling or being sick, joint or muscle pain. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before taking Lopid 600 Tablet , tell your doctor if you are allergic to any fibrate products. Inform your doctor if you ever had rhabdomyolysis (high risk of muscle breakdown), thyroid disease, history of muscle pain and weakness. If you are above 70 years, then contact your doctor before taking this Lopid 600 Tablet . Before starting Lopid 600 Tablet , please inform your doctor if you have any allergy, severe kidney disease, severe liver disease, and gallbladder disease before starting $ name. Inform your doctor if you have ever had gallstones, cataracts (clouding in the eye's lens that causes decreased vision), diabetes, and heart disease. Inform your doctor if you have taken other cholesterol medicines with this Lopid 600 Tablet . Immediately contact your doctor if you are pregnant and breastfeeding. The use of alcohol with Lopid 600 Tablet increases liver damage, so its use should be avoided.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Lopid 600 Tablet:
When Repaglinide is taken with Lopid 600 Tablet, the level of Repaglinide in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Repaglinide with Lopid 600 Tablet can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lopid 600 Tablet:
When Selexipag is taken with Lopid 600 Tablet, the amount of Selexipag in the blood can go up. This can increase the risk or severity of side effects like anemia, muscle and joint pain, or electrolyte imbalance.

How to manage the interaction:
Taking Selexipag with Lopid 600 Tablet can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle and joint pain, diarrhea, sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, flushing, and decreased appetite, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GemfibrozilDicoumarol
Severe
How does the drug interact with Lopid 600 Tablet:
Co-administration of Lopid 600 Tablet and Dicoumarol can increase the effects of Dicumarol and cause bleeding.

How to manage the interaction:
Although there is a possible interaction between Lopid 600 Tablet and Dicoumarol, you can take these medicines together if prescribed by a doctor. If you notice any of these symptoms - bruises, vomiting, bleeding, headache, dizziness, or weakness - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lopid 600 Tablet:
When Lopid 600 Tablet is used with Pitavastatin, the chance of side effects such as liver damage and rhabdomyolysis(an uncommon but dangerous illness characterized by the breakdown of skeletal muscle tissue) increases.

How to manage the interaction:
Although there is a possible interaction between Pitavastatin and Lopid 600 Tablet, you can take these medicines together if advised by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, tiredness, nausea, vomiting, abdominal pain, dark urine, light stools, yellowing of the skin or eyes, muscle pain, tenderness, and/or weakness, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Lopid 600 Tablet:
When taken in combination Lopid 600 Tablet may significantly raise the Loperamide levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Loperamide with Lopid 600 Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lopid 600 Tablet:
When Pioglitazone is taken with Lopid 600 Tablet, the level of Pioglitazone in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Pioglitazone with Lopid 600 Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience visual abnormalities, excessive or quick weight gain, swelling in the ankles or legs, trouble breathing, unusual fatigue, chest discomfort or tightness, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, light coloured stools, or yellowing of the skin or eyes, seek medical attention immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lopid 600 Tablet:
When Lopid 600 Tablet is taken with Atorvastatin, the chance of side effects such as liver damage and rhabdomyolysis, (an uncommon illness involving the breakdown of skeletal muscle tissue) increases.

How to manage the interaction:
Co-administration of Atorvastatin along with Lopid 600 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
GemfibrozilPravastatin
Severe
How does the drug interact with Lopid 600 Tablet:
Taking Lopid 600 Tablet with Pravastatin can increase the risk or severity of muscle damage or liver damage.

How to manage the interaction:
Although taking Pravastatin and Lopid 600 Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lopid 600 Tablet:
Co-administration of Warfarin with Lopid 600 Tablet can increase the risk of bleeding.

How to manage the interaction:
Although taking Lopid 600 Tablet and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
GemfibrozilCerivastatin
Severe
How does the drug interact with Lopid 600 Tablet:
C-administration of Lopid 600 Tablet with Cerivastatin can develop or increase the risk of liver damage or rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Lopid 600 Tablet with Cerivastatin together can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and contact your doctor right away if you notice any of these signs - liver problems, muscle damage, kidney problems, complications, pain, weakness, fever, dark urine, chills, joint pain, swelling, bruising, rash, itching, loss of appetite, tiredness, feeling sick, or bleeding. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Lopid 600 Tablet is generally given in addition to regular exercise and a low-fat diet to lower fat levels in the blood.

  • A low cholesterol diet and a regular exercise regime are found to complement treatment with Lopid 600 Tablet effectively.

  • As a precautionary measure, you are recommended not to consume alcohol, junk food items from outside, stick to freshly prepared home-cooked meals and take proper rest, for a speedy recovery.

  • Try to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol in a short span of time.

  • Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so it is beneficial to eat them regularly.

  • Regular exercise can make your heart strong and decrease your risk of a heart attack.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS
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Alcohol

Unsafe

Alcohol may interact with Lopid 600 Tablet . Therefore, avoid the use of alcohol while taking this Lopid 600 Tablet .

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Pregnancy

Unsafe

It is not known whether Lopid 600 Tablet will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant while using this Lopid 600 Tablet .

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Breast Feeding

Unsafe

It is unknown whether Lopid 600 Tablet passes into breast milk or if it could harm a nursing baby. It would be best if you did not breast-feed while taking Lopid 600 Tablet .

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Driving

Caution

Although unlikely, you may feel dizzy or experience visual disturbances whilst taking this Lopid 600 Tablet .

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Liver

Caution

Lopid 600 Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Lopid 600 Tablet to be taken with caution, especially if you have a history of kidney disease or is currently on the dialysis stage. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Lopid 600 Tablet is not recommended for children.

Have a query?

FAQs

Lopid 600 Tablet is used to treat raised or increased levels of cholesterol or fat/oils.

Yes, you may use Lopid 600 Tablet with niacin if recommended by your doctor because Lopid 600 Tablet along with niacin can be used in patients with very high fat.

Follow the diet suggested by your doctor. Lopid 600 Tablet will not help lower your cholesterol if you do not follow a cholesterol-lowering diet plan. Avoid drinking alcohol. It may disturb your treatment.

Usually, it is not safe to take Lopid 600 Tablet with fusidic acid as it may lead to muscle weakness, tenderness or pain. Please consult your doctor before taking Lopid 600 Tablet along with fusidic acid.

You should not take Lopid 600 Tablet if you have gallbladder disease, severe liver or kidney disease. If you are also taking repaglinide or simvastatin, then you should not take Lopid 600 Tablet .

Lopid 600 Tablet is used with caution in patients taking warfarin, adjustments in warfarin may be required, consult your doctor before taking Lopid 600 Tablet along with warfarin.

Lopid 600 Tablet is a fibrate. It belongs to the group of medications called fibric acid derivatives. It is used in the treatment of high cholesterol levels.

Yes, Lopid 600 Tablet is generally considered safe when used as directed by your doctor. However, like all medications, it can cause side effects and interact with other drugs. Common side effects are usually mild and temporary, but rare cases of more serious side effects can occur. To ensure safe use, it's essential to follow your doctor's instructions and dosage, inform your doctor about all medications, supplements, and medical conditions, and monitor your liver function and blood counts regularly. By being mindful of these factors and reporting any side effects or concerns to your doctor, you can minimize risks and enjoy the benefits of Lopid 600 Tablet .

Lopid 600 Tablet and fenofibrate are two different medications for treating high cholesterol and triglycerides. They belong to the same class of drugs but have distinct differences. Fenofibrate is often used first to treat high triglycerides, while gemfibrozil is reserved for patients who can't take other medications. They are not interchangeable; your doctor will determine which is best for you.

Using Lopid 600 Tablet together with simvastatin is not recommended. Combining these medications can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue.

Lopid 600 Tablet is not usually linked to weight changes, hair loss, constipation, or erectile dysfunction. However, it can cause diarrhoea in some people. If you notice any unusual symptoms, you must talk with your doctor to determine the cause and make any necessary adjustments to your treatment.

Country of origin

INDIA

Manufacturer/Marketer address

The Capital, 1802, 18Th Floor , Plot No. C-70, €˜G’ Block , Bandra Kurla Complex, Bandra East , Mumbai €“ 400051
Other Info - LOP0006

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