PIOGLITAZONE is an anti-diabetic medicine belonging to the class of thiazolidinedione (TZD), also called 'glitazones', used to treat type 2 (non-insulin-dependent) diabetes mellitus. Type 2 diabetes is an illness where the body doesn't make enough insulin, or the insulin that it makes doesn't work properly. This is diabetes that usually develops in adulthood.
PIOGLITAZONE contains Pioglitazone which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces. Your doctor will check whether Pioglitazone is working 3-6 months after you start taking it.
PIOGLITAZONE should be taken with food or an empty stomach. However, it should be taken at the same time of the day each time for the best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition. The most common side effect of PIOGLITAZONE is upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain), and pharyngitis. Most of these side effects of PIOGLITAZONE do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.
PIOGLITAZONE should not be stopped even if you feel better without consulting your doctor as sugar levels change. If you stop taking PIOGLITAZONE suddenly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney damage (nephropathy) and nerve damage (neuropathy). PIOGLITAZONE should not be taken if you have type 1 diabetes mellitus, if you are hypersensitive (allergic) to PIOGLITAZONE or any of the other ingredients of PIOGLITAZONE, have heart failure or have had heart failure in the past, diabetic ketoacidosis (a complication of diabetes causing rapid weight loss, nausea or vomiting), severe kidney or liver disease, bladder cancer. Please inform your doctor if you have any heart disease, are or planning to get pregnant or breastfeeding. The safety and efficacy of PIOGLITAZONE in children under 18 years have not been established, so it should not be given to them.
Type 2 diabetes mellitus
PIOGLITAZONE is an antidiabetic drug (thiazolidinedione/glitazones) used along with a proper diet and exercise to control high blood sugar (hyperglycaemia) in patients with type 2 diabetes. PIOGLITAZONE works by helping to restore your body's appropriate response to insulin, thereby lowering your blood sugar.
Fluid retention (oedema) may occur and can lead to congestive heart failure so, a combination of use with insulin and use in heart failure may increase the risk in patients taking PIOGLITAZONE. You should not take PIOGLITAZONE if you have kidney disease, as measured by a blood test. PIOGLITAZONE, when used with or without insulin, $ name tends to lower the blood sugar level. So, the doctor may lower the dose of insulin. Increased fractures may be reported in some women taking PIOGLITAZONE. Patients with bladder cancer and macular oedema (fluid build-up in the macula part of the retina of the eye) should consult the doctor before using PIOGLITAZONE.
Drug-Drug Interactions: PIOGLITAZONE may interact with antidiabetics (gemfibrozil), and antibiotics (rifampicin). So, tell your doctor if you are using these drugs before taking PIOGLITAZONE.
Drug-Food Interactions: Taking PIOGLITAZONE with alcoholic beverages may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis (build-up of lactic acid in the blood) and hypoglycaemia.
Drug-Disease Interactions: PIOGLITAZONE should be avoided in patients with congestive heart failure (heart-related issues), type I diabetes, bladder cancer, oedema, liver disease, macular oedema, premenopausal anovulation, obesity (weight gain), anaemia as it may worsen the condition.
You are recommended not to consume alcohol along with PIOGLITAZONE to avoid unpleasant side-effects.
PIOGLITAZONE is not generally recommended in pregnancy. It's not clear whether pioglitazone can harm your unborn baby. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.
It is highly recommended to consult your doctor before taking PIOGLITAZONE.
PIOGLITAZONE will not affect your ability to drive or use machines but take care if you experience abnormal vision.
PIOGLITAZONE to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
PIOGLITAZONE to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
The safety and efficacy of PIOGLITAZONE in children have not been established. PIOGLITAZONE is not recommended in children.
Type 2 diabetes is a chronic or lifelong disease that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin or resist insulin action. Middle-aged or older are most likely to suffer from type 2 diabetes, also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. There may be weight gain in some cases, while weight loss may be observed in rare cases. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and increase the chance of heart attack or stroke.
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