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Lupihist-DM Plus Syrup 100 ml
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More about the Product

Composition :

CHLORPHENIRAMINE-2MG+DEXTROMETHORPHAN-10MG+PHENYLEPHRINE-5MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lupihist-DM Plus Syrup

Lupihist-DM Plus Syrup belongs to a class of antiarrhythmic medicines used to treat irregular heartbeats (arrhythmias) and protect the heart during the early stages after a heart attack (myocardial infarction), which occurs when the heart muscle does not receive enough blood and oxygen.

Lupihist-DM Plus Syrup contains Atenolol, which works by blocking certain natural substances in the heart and blood vessels. This slows the heart rate and reduces blood pressure, lowering the risk of heart attack, stroke, and kidney problems.

Lupihist-DM Plus Syrup is administered by a healthcare professional; do not self-administer. Some people may experience cold hands or feet, diarrhoea, nausea, or tiredness. These side effects usually resolve over time, but consult your doctor if they persist or worsen.

Before using Lupihist-DM Plus Syrup , inform your doctor if you have any allergies to its ingredients, are pregnant, planning pregnancy, or breastfeeding. For pediatric use, the dose and duration must be determined by a paediatrician and administered under strict medical supervision. Additionally, provide your doctor with your complete medical history and details of any current medications to minimise the risk of adverse effects or drug interactions.

Uses of Lupihist-DM Plus Syrup

Lupihist-DM Plus Syrup is used to treat dry cough. The detailed uses of Lupihist-DM Plus Syrup are as follows:

  • Cough Relief: Lupihist-DM Plus Syrup is designed to provide cough relief, especially for dry coughs, by utilising its antitussive properties to calm throat irritation and reduce the urge to cough.
  • Allergy Relief: Lupihist-DM Plus Syrup can help to alleviate allergy symptoms like a runny nose and sneezing, offering relief for individuals who experience seasonal allergic reactions.
  • Soothing Sore Throat: Lupihist-DM Plus Syrup helps to calm a sore throat caused by coughing or irritation, making swallowing easier and reducing throat discomfort.
  • Decongestant: Lupihist-DM Plus Syrup contains Phenylephrine, a decongestant that reduces nasal congestion by shrinking swollen blood vessels in the nasal passages.

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Side effects of Lupihist-DM Plus Syrup 100 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Try to get 7-9 hours of sleep per night.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is cool, quiet and dark to maximize your sleep quality.
  • Get plenty of sunlight in the morning.
  • Do moderate-intensity exercises most days of the week and avoid strenuous exercise close to bedtime.
  • Limit processed foods and sugary drinks.
  • Avoid caffeine late in the day and drink in moderation in the morning.
  • Take short nap (20 to 30 minutes) mid-afternoon if required.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Directions for Use

  • Lupihist-DM Plus Syrup can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Measure the prescribed dose using a measuring cup and administer it orally.
  • Avoid using regular household spoons, as they may not measure the dose correctly.
  • Shake the bottle well before use.

Key Benefits

  • Lupihist-DM Plus Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough.
  • Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness.
  • Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose.
  • Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.
  • Thus, Lupihist-DM Plus Syrup helps to relieve overall cough, cold and allergic symptoms.

How Lupihist-DM Plus Syrup Works

Lupihist-DM Plus Syrup is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine (decongestant), and Dextromethorphan (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps shrink blood vessels in the nasal passages, thereby reducing a stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Collectively, it helps relieve a dry cough.

What if I have taken an overdose of Lupihist-DM Plus Syrup

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include agitation, flushing, confusion, hallucinations, muscle twitching, large pupils, and seizures. In children, excitement may occur first, followed by loss of coordination, drowsiness, loss of consciousness, and seizures. If you/your child experiences these symptoms or suspects that an overdose has occurred, seek immediate medical attention.

Drug Warnings

  • If you are allergic to Lupihist-DM Plus Syrup or any other medicines, please tell your doctor.
  • If you are pregnant or breastfeeding, it is advised to inform your doctor before using it.
  • Lupihist-DM Plus Syrup is not recommended for use in infants or toddlers without medical advice.
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking this medicine.
  • Avoid taking Lupihist-DM Plus Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days.
  • If you have glaucoma, urinary problems, an enlarged prostate, phenylketonuria (a birth defect that causes accumulation of the amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Lupihist-DM Plus Syrup .

Drug-Drug Interactions

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DextromethorphanRasagiline
Critical
DextromethorphanPargyline
Critical

Drug-Drug Interactions

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DextromethorphanRasagiline
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Taking Rasagiline with Lupihist-DM Plus Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Lupihist-DM Plus Syrup 100 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanPargyline
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Co-administration of Pargyline and Lupihist-DM Plus Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Lupihist-DM Plus Syrup 100 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Co-administration of Isocarboxazid with Lupihist-DM Plus Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Lupihist-DM Plus Syrup 100 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanProcarbazine
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Co-administration of Lupihist-DM Plus Syrup 100 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Lupihist-DM Plus Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanSelegiline
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Co-administration of Lupihist-DM Plus Syrup 100 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Lupihist-DM Plus Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanPhenelzine
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Co-administration of Phenelzine and Lupihist-DM Plus Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Lupihist-DM Plus Syrup 100 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Taking Tranylcypromine with Lupihist-DM Plus Syrup 100 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Lupihist-DM Plus Syrup 100 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Taking Furazolidone with Lupihist-DM Plus Syrup 100 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Lupihist-DM Plus Syrup 100 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Lupihist-DM Plus Syrup 100 ml only after 14 days of stopping Furazolidone.
PhenylephrineTranylcypromine
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Taking Tranylcypromine with Lupihist-DM Plus Syrup 100 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Lupihist-DM Plus Syrup 100 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
PhenylephrinePropofol
Critical
How does the drug interact with Lupihist-DM Plus Syrup 100 ml:
Taking Lupihist-DM Plus Syrup 100 ml with Propofol may lead to increased levels of Lupihist-DM Plus Syrup 100 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Lupihist-DM Plus Syrup 100 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as they may increase mucus production. Also, avoid processed or refined foods to relieve a cough.
  • Drink plenty of fluids to avoid a dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

[COUGH AND COLD PREPARATIONS ]
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Alcohol

Caution

Avoid consumption of alcohol with Lupihist-DM Plus Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Lupihist-DM Plus Syrup .

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Pregnancy

Caution

The safety of Lupihist-DM Plus Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Lupihist-DM Plus Syrup is excreted in human milk. Lupihist-DM Plus Syrup is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Lupihist-DM Plus Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Lupihist-DM Plus Syrup .

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Liver

Caution

Take Lupihist-DM Plus Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Lupihist-DM Plus Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

The dose and duration must be determined by a paediatrician and administered under strict medical supervision.

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Heart

Unsafe

Lupihist-DM Plus Syrup is contraindicated in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Unsafe

Lupihist-DM Plus Syrup is not safe for use in elderly patients due to its severe side effects.

FAQs

Lupihist-DM Plus Syrup is used to treat dry cough.

Lupihist-DM Plus Syrup is a combination drug, primarily used to treat dry cough. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a 'decongestant' that helps in shrinking the blood vessels located in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.

Consuming alcohol, along with Lupihist-DM Plus Syrup , may potentiate some of the pharmacologic effects of CNS-active agents. If used together, it may lead to symptoms like confusion, central nervous system depression, impairment of thinking and judgment.

No, you should not take Lupihist-DM Plus Syrup if you need to undergo surgery, as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Please inform your doctor before surgery if you are taking Lupihist-DM Plus Syrup as the doctor may stop it 72 hours before the surgery.

It is not recommended to take Lupihist-DM Plus Syrup along with any antidepressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side effects or any drug interaction. Also, Lupihist-DM Plus Syrup should be taken at least 15 days after your last dose of antidepressants.

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Lupihist-DM Plus Syrup and skip the missed dose. Do not take extra medicine to make up for the missed dose.

Lupihist-DM Plus Syrup should be used with caution, only when prescribed by a doctor, in patients with glaucoma. As Lupihist-DM Plus Syrup may rarely worsen the symptoms of glaucoma.

Yes, Lupihist-DM Plus Syrup can cause sleepiness or drowsiness as a common side effect. Lupihist-DM Plus Syrup contains dextromethorphan and phenylephrine, which can cause drowsiness, dizziness, nausea, dry mouth, and headache. Therefore, avoid activities that require mental alertness until you know how Lupihist-DM Plus Syrup affects you.

No, taking Lupihist-DM Plus Syrup at a dose higher than recommended will not make it more effective; it can actually be harmful. Overdosing can lead to severe side effects and toxicity. Therefore, follow your doctor’s instructions carefully.

It is unknown whether Lupihist-DM Plus Syrup passes into human milk. Therefore, please consult your doctor if you are supposed to breastfeed while taking Lupihist-DM Plus Syrup . Your doctor will prescribe Lupihist-DM Plus Syrup only if the benefits outweigh the risks.

Store at a temperature not exceeding 30°C in a cool and dry place. Protect it from sunlight and moisture. Keep out of reach of children.

Lupihist-DM Plus Syrup is primarily used to treat dry cough and relieve allergy symptoms such as a runny nose, stuffy nose, sneezing, and watery eyes. However, it is not typically recommended for chronic cough or asthma. Therefore, please consult your doctor for appropriate medications and treatments for chronic cough or asthma.

Both Lupihist-DM Plus Syrup and other cold or allergy medicines may contain dextromethorphan, phenylephrine, and chlorpheniramine as active components. Therefore, combining cold or allergy medicines with Lupihist-DM Plus Syrup increases the chance of side effects. So, always consult your doctor before combining Lupihist-DM Plus Syrup with other medicines.

Avoid alcohol that can increase the drowsiness and dizziness caused by Lupihist-DM Plus Syrup . Inform your doctor if you have any pre-existing conditions, such as heart, kidney, lung, liver, thyroid problems, diabetes, glaucoma, or prostate issues. Inform your doctor if you are taking other medications, or if you are breastfeeding, pregnant or planning pregnancy. Drink plenty of fluids while taking Lupihist-DM Plus Syrup to loosen mucus. Take Lupihist-DM Plus Syrup exactly as prescribed by your doctor. Do not exceed the recommended dose.

It is not known whether Lupihist-DM Plus Syrup can cause fetal harm. Therefore, please consult your doctor if you are pregnant before taking Lupihist-DM Plus Syrup . Your doctor will prescribe Lupihist-DM Plus Syrup only if the benefits outweigh the risks.

The duration for using Lupihist-DM Plus Syrup depends on the severity of your symptoms and your doctor's advice. Generally, it is meant for short-term use to relieve symptoms like dry cough, runny nose, and sneezing. Follow your doctor's instructions on how long to use it and consult your doctor if you have any concerns.

The common side effects of Lupihist-DM Plus Syrup are dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness or excitation. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Other Info - LUP0182

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Author Details

Veda MaddalaDoctor badge

Written By

  • Veda Maddala

    M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

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