Lupisit-GM 1/1000 Tablet 10's
MRP ₹134
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About Lupisit-GM 1/1000 Tablet
Lupisit-GM 1/1000 Tablet is an antidiabetic medicine used to treat type II diabetes. Type II Diabetes Mellitus is a serious condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels.
Lupisit-GM 1/1000 Tablet works by reducing the sugar production by cells in the liver and delaying sugar absorption from the intestine, increasing the amounts of certain natural substances that lower blood sugar when it is high, and stimulating beta cells in the pancreas that produce insulin.
Lupisit-GM 1/1000 Tablet may cause certain side effects, such as vomiting, nausea, abdominal pain, headache, frequent urination, and allergic reactions. If these side effects persist or worsen, please consult your doctor. Lupisit-GM 1/1000 Tablet should be taken as prescribed by your doctor.
Do not take Lupisit-GM 1/1000 Tablet if you are allergic to any of its components. Inform your doctor about your medical and complete medication history, including herbs and supplements, before starting the treatment with Lupisit-GM 1/1000 Tablet . Let your doctor know if you are pregnant or breastfeeding.
Uses of Lupisit-GM 1/1000 Tablet
Lupisit-GM 1/1000 Tablet is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Lupisit-GM 1/1000 Tablet are as follows:
- Type 2 diabetes management: Lupisit-GM 1/1000 Tablet helps manage elevated blood sugar levels when lifestyle modifications and single-drug treatments do not provide sufficient control.
- Glycemic balance support: Lupisit-GM 1/1000 Tablet controls blood sugar levels throughout the day, including after meals and during fasting periods.
- Enhanced insulin function: Lupisit-GM 1/1000 Tablet improves the body’s ability to use insulin effectively by increasing insulin sensitivity and encouraging the pancreas to release insulin as needed.
- Reduced liver glucose output: Lupisit-GM 1/1000 Tablet helps decrease the amount of glucose produced by the liver, which is particularly useful for lowering blood sugar levels during early morning hours.
- Prevention of complications: By maintaining stable blood sugar over time, Lupisit-GM 1/1000 Tablet helps lower the risk of diabetes-related complications such as nerve damage, kidney issues, eye problems, and heart conditions.
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Directions for Use
- Take Lupisit-GM 1/1000 Tablet with food to reduce stomach upset or gastrointestinal side effects.
- Recommended to take it once daily in the morning or as advised by your doctor.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Medicinal Benefits
- Lupisit-GM 1/1000 Tablet is a combination anti-diabetic medicine used to manage Type 2 Diabetes Mellitus along with proper diet and exercise.
- It contains Sitagliptin, Metformin, and Glimepiride, which work together to effectively control blood sugar levels.
- Glimepiride (a sulfonylurea) increases insulin release from the pancreas, helping the body utilise glucose effectively.
- Metformin (a biguanide) decreases glucose production in the liver and delays carbohydrate absorption from the intestines.
- Sitagliptin (a DPP-4 inhibitor) increases levels of incretin hormones, which stimulate insulin release and lower blood sugar when blood glucose is high.
- It promotes the elimination of glucose through urine, aiding in better blood sugar control.
- Consistent blood sugar management helps reduce the risk of heart disease, kidney damage, nerve problems, and vision issues associated with diabetes.
How Lupisit-GM 1/1000 Tablet Works
Storage
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
- Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
- Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
- Make medication adjustments as recommended by your doctor to prevent future episodes.
- Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
- Monitor your blood sugar levels closely for patterns and changes.
- Track your progress by recording your blood sugar levels, food intake, and physical activity.
- Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
What if I have taken an overdose of Lupisit-GM 1/1000 Tablet
Drug Warnings
- Lupisit-GM 1/1000 Tablet should be avoided if you are allergic to any of the components in it.
- Lupisit-GM 1/1000 Tablet is not recommended for use in patients with severe liver or kidney disease.
- It is unknown whether Lupisit-GM 1/1000 Tablet can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding.
- It is not recommended for use in children below 18 years of age.
- Avoid drinking alcohol while on Lupisit-GM 1/1000 Tablet , as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).
- Before starting the treatment, inform your doctor about your medical history and the medications you take, including herbs and supplements. This can help prevent unwanted effects.
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Lupisit-GM 1/1000 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Gatifloxacin is not recommended as it can lead to a possible interaction, However, it can be taken if advised by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without a doctor's advice.
Co-administration of Iofendylate with Lupisit-GM 1/1000 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Lupisit-GM 1/1000 Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Lupisit-GM 1/1000 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Iomeprol with Lupisit-GM 1/1000 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Ioglycamic acid with Lupisit-GM 1/1000 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Lupisit-GM 1/1000 Tablet and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.
Co-administration of Ioglicic acid with Lupisit-GM 1/1000 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Iohexol with Lupisit-GM 1/1000 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Iotroxic acid with Lupisit-GM 1/1000 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Lupisit-GM 1/1000 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day.
- Invest at least 150 minutes of your week in exercise.
- Maintain a healthy body weight, as obesity is also related to the onset of diabetes.
- Maintain a low-fat and low-sugar diet.
- Replace carbohydrate-containing foods with whole grains, fruits and vegetables, as carbohydrates turn to sugars, leading to high blood sugar.
- Avoid consumption of alcohol and quit smoking.
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Alcohol
Unsafe
Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Lupisit-GM 1/1000 Tablet .
Pregnancy
Caution
There are no adequate studies on the effect of Lupisit-GM 1/1000 Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Lupisit-GM 1/1000 Tablet .
Breast Feeding
Caution
Lupisit-GM 1/1000 Tablet is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Lupisit-GM 1/1000 Tablet .
Driving
Safe
Lupisit-GM 1/1000 Tablet usually does not affect your ability to drive or operate machinery.
Liver
Caution
Lupisit-GM 1/1000 Tablet may cause lactic acidosis due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
Caution
Renal impairment also increases the risk of lactic acidosis. Hence, Lupisit-GM 1/1000 Tablet should be used cautiously if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Unsafe
Lupisit-GM 1/1000 Tablet is not recommended for children below 18 years, as the safety and effectiveness have not been established.
Heart
Take Lupisit-GM 1/1000 Tablet with caution, especially if you have a history of heart disease. Inform your doctor before receiving the Lupisit-GM 1/1000 Tablet if you have a history of heart diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Geriatrics
Caution
Lupisit-GM 1/1000 Tablet should be used with caution in elderly patients. Please consult your doctor before use.
FAQs
Lupisit-GM 1/1000 Tablet is an antidiabetic medicine used to treat type II diabetes.
Lupisit-GM 1/1000 Tablet is a combination medicine containing Sitagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines. Glimepiride works by stimulating beta cells in the pancreas that produce insulin.
If you forget to take Lupisit-GM 1/1000 Tablet , take it as soon as you remember. However, if it is time for the next dose, avoid taking it and do not double-dose to make up the missed dose. Taking an overdose might cause your sugar level to fall rapidly.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022044s022lbl.pdf
- https://medlineplus.gov/druginfo/meds/a606023.html
- https://www.drugs.com/metformin.html
- https://www.nhs.uk/medicines/sitagliptin/about-sitagliptin/#:~:text=Sitagliptin%20is%20prescribed%20for%20people,is%20only%20available%20on%20prescription.
