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compositionComposition:SERRATIOPEPTIDASE-5MG
prescription
Prescription Medicine
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Lyo-5 Tablet 10's is used to provide pain relief in various conditions, including post-traumatic pain, low back pain, cervical pain, spondylitis (inflammation in spinal bones), osteoarthritis (lifelong joint pain and stiffness), rheumatoid arthritis(joint pain and damage throughout the body). It contains Serratiopeptidase, which breaks the insoluble protein (fibrin) into smaller units. It also causes thinning of the body's fluids, making fluid drainage smoother in the swollen tissue and relieving inflammation at the affected or injured site. In some cases, it may cause stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SERRATIOPEPTIDASE-5MG

Manufacturer/Marketer :

Rajput Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Lyo-5 Tablet 10's

Lyo-5 Tablet 10's is an oral enzyme preparation used to reduce swelling, inflammation, and associated pain. It is commonly prescribed to help clear fluid accumulation in tissues after surgeries, physical injuries, or respiratory conditions like sinus congestion. By breaking down abnormal proteins at inflammatory sites, it aids the body's natural healing process.

For best results, take Lyo-5 Tablet 10's consistently at the exact intervals prescribed by your doctor. It must be taken on an empty stomach, either 30 minutes before a meal or 2 hours after, to prevent the enzyme from breaking down dietary proteins instead of working on your body's tissues. Staying well-hydrated and resting the affected area can also help speed up your recovery.

While taking Lyo-5 Tablet 10's, some individuals may experience mild stomach upset, nausea, or a temporary loss of appetite. If you notice any serious side effects, such as unusual bleeding, skin rashes, or breathing difficulties, you should seek immediate medical attention. Always consult your doctor if any unusual symptoms persist or worsen.

Talk to your doctor before starting Lyo-5 Tablet 10's if you have a history of bleeding disorders, liver disease, or kidney problems. Do not take this medicine if you have a known allergy to proteolytic enzymes or are scheduled for an upcoming surgery. It is highly recommended to avoid this medication if you have active bleeding conditions, such as bleeding ulcers.

Avoid taking Lyo-5 Tablet 10's with blood thinners, as this combination increases your risk of bruising and bleeding. Smoking and alcohol consumption should be avoided, as they can worsen inflammation and delay your body's recovery. If you are pregnant, breastfeeding, or an older adult, consult your healthcare provider to ensure this medication is safe for your specific situation.

Uses of Lyo-5 Tablet 10's

Lyo-5 Tablet 10's is used to reduce swelling, inflammation, and associated pain. The detailed uses of Lyo-5 Tablet 10's are as follows:

  • Post-operative swelling: Helps reduce fluid buildup, swelling, and inflammation at surgical incision sites for a smoother recovery.
  • Traumatic injuries: Aids in relieving pain and swelling caused by sports injuries, sprains, fractures, or muscle tears.
  • Sinusitis and respiratory congestion: Thins mucus secretions in the sinuses and airways, making it easier to clear congestion and breathe comfortably.
  • Inflammatory joint conditions: Assists in managing swelling and stiffness in conditions affecting the joints and surrounding tissues.
     

Key Benefits

Lyo-5 Tablet 10's helps reduce swelling and inflammation, promoting faster recovery from injuries, surgery, or inflammatory conditions. By improving tissue healing and relieving discomfort, it supports better mobility and overall recovery.

  • Helps Reduce Swelling and Pain: By reducing inflammation and the accumulation of excess fluid, Lyo-5 Tablet 10's helps relieve swelling, pain, and pressure at the affected area, improving comfort during daily activities.
  • Supports Comfortable Movement: As swelling and inflammation decrease, Lyo-5 Tablet 10's helps improve mobility and allows for more comfortable movement during the healing process.
  • Promotes Faster Tissue Recovery: By supporting the clearance of excess fluid and improving circulation at the affected site, Lyo-5 Tablet 10's helps promote the body's natural tissue repair process and contributes to a smoother recovery following injury or surgery.
     

Directions for Use

  • Lyo-5 Tablet 10's can be taken 2 hours after meals, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Lyo-5 Tablet 10's as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Lyo-5 Tablet 10's Works

Lyo-5 Tablet 10's contains serratiopeptidase. It works as a proteolytic enzyme, which means it specialises in breaking down proteins. When there is tissue injury or inflammation, the body produces excess proteins like fibrin and fluids that cause swelling and pain. Lyo-5 Tablet 10's targets and breaks down these abnormal proteins at the site of inflammation. This process thins out the inflammatory fluids, making it easier for your lymphatic system to drain them away. By reducing fluid pressure and clearing blockages, it decreases swelling and eases pressure on nearby nerves, relieving pain and discomfort.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Lyo-5 Tablet 10's to avoid unpleasant side-effects.

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Pregnancy

Unsafe

The use of Lyo-5 Tablet 10's may impair female fertility and is not recommended in pregnant women or those planning for pregnancy.

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Breast Feeding

Unsafe

Lyo-5 Tablet 10's passes into the breast milk so it is not recommended for nursing mothers.

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Driving

Unsafe

Lyo-5 Tablet 10's may affect driving as it causes dizziness. So do not drive a motor vehicle or operate heavy machinery after taking Lyo-5 Tablet 10's.

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Liver

Caution

Lyo-5 Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Lyo-5 Tablet 10's to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor

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Children

Unsafe

Lyo-5 Tablet 10's is not recommended for children under 10 years of age. For the dose has to be adjusted and recommended by a child specialist only.

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Heart

Unsafe

Lyo-5 Tablet 10's is not recommended for use in cardiac patients due to the cardiovascular effects.

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Geriatrics

Caution

Lyo-5 Tablet 10's should be used with caution in elderly patients due to the risk of other adverse effects.

What if I have taken an overdose of Lyo-5 Tablet 10's

If you suspect an overdose or experience severe symptoms such as heavy bleeding or severe nausea, seek immediate medical attention or contact your local emergency health services.

Diet & Lifestyle Advise

  • Drink plenty of water daily to help thin secretions and aid the lymphatic system in clearing broken-down inflammatory proteins.
  • Incorporate anti-inflammatory foods into your diet, such as leafy greens, berries, and omega-3-rich foods, to support your body's healing process.
  • Keep the injured or swollen limb elevated when resting to help reduce fluid pooling and accelerate swelling reduction.
  • Avoid heavy, greasy foods around the time you take your medication to prevent stomach irritation.
     
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How Soon It Starts Working

The time required for Lyo-5 Tablet 10's to start to work: The time required for Lyo-5 Tablet 10's to show its action is unknown. The time for which the effects of Lyo-5 Tablet 10's last: The effect of Lyo-5 Tablet 10's lasts for 8 to 10 hours.

What if you forget to take Lyo-5 Tablet 10's

If you miss a dose of Lyo-5 Tablet 10's, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

Store Lyo-5 Tablet 10's tablets in their original packaging at room temperature, ideally between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Check the tablet blister pack before use; do not take the medication if the packaging is damaged or the tablet is cracked.
  • Stop taking Lyo-5 Tablet 10's at least two weeks before any scheduled dental or surgical procedure, as it can increase the risk of bleeding.
  • Do not substitute this medication with other digestive enzyme supplements without consulting your healthcare provider first.
  • Monitor your skin daily for any signs of unexplained bruising or red spots, and report them to your doctor immediately.
  • If your swelling or pain does not improve after a week of consistent use, contact your doctor to re-evaluate your condition.
     

verifiedApollotooltip
  • Blood thinners (e.g., warfarin, heparin), antiplatelet medicines (e.g., clopidogrel), and NSAIDs (e.g., aspirin, ibuprofen): Taking Lyo-5 Tablet 10's with medicines that affect blood clotting may increase the risk of bleeding or bruising. Your doctor may recommend closer monitoring if these medicines are used together.
     

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verifiedApollotooltip
  • Food: Taking Lyo-5 Tablet 10's with food may reduce its absorption and effectiveness because the enzyme may act on dietary proteins instead of reaching inflamed tissues. For best results, take the medicine as directed by your healthcare provider, usually on an empty stomach if recommended.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Lyo-5 Tablet 10's is used to provide pain relief in various conditions, including post-traumatic pain, low back pain, cervical pain, spondylitis (inflammation in spinal bones), osteoarthritis (lifelong joint pain and stiffness), rheumatoid arthritis (joint pain and damage throughout the body).
A person who is allergic to pain-killers should not take this medicine as it can be harmful. It should also be avoided in a person with a history of heart failure, kidney or liver disease, stomach ulcers, and high blood pressure.
Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation and pain in the joints. In this condition, our body attacks its own cells leading to arthritis.
Ankylosing spondylitis is arthritis of the spine that can lead to the fusion of the vertebrae, leading to pain and inflammation in the spine.
Yes, Lyo-5 Tablet 10's can cause stomach upset in some cases. So, it should be preferably taken with food to avoid it.
No, Lyo-5 Tablet 10's is not a steroid. Lyo-5 Tablet 10's belongs to the class of drugs called anti-inflammatory agents used to relieve inflammation and pain.
No, Lyo-5 Tablet 10's is not addictive. It does not have habit-forming tendencies.
Yes, Lyo-5 Tablet 10's provides relief from toothache by reducing inflammation near affected dental tissue.
Lyo-5 Tablet 10's contains an enzyme called serratiopeptidase which works by modifying cell- surface adhesion molecules which are responsible for inflammation. Thereby, Lyo-5 Tablet 10's helps to treat inflammation.
Side effects of Lyo-5 Tablet 10's include stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects resolve over time and do not require medical intervention. However, consult the doctor if the side effects persist or worsen.
Let the doctor know if you have any surgery scheduled within two weeks or if you are using anticoagulant medications. Consult your doctor before taking Lyo-5 Tablet 10's if you are pregnant and breastfeeding.
Store Lyo-5 Tablet 10's in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
Lyo-5 Tablet 10's contains serratiopeptidase, a proteolytic enzyme that helps treat inflammation associated with various conditions.
No, Lyo-5 Tablet 10's should be taken on an empty stomach—either 30 minutes before a meal or 2 hours after. Taking it with food can cause the enzyme to break down your food instead of targeting inflammation in your body. Talk to your doctor if you have questions about how to schedule your doses.
The time it takes to see results varies depending on the severity of your swelling or inflammation. Many patients begin to notice relief within 3 to 5 days of consistent use. Talk to your doctor if your symptoms do not improve after a week.
While it can be taken with some pain medications, you should avoid taking it with certain nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin or ibuprofen without medical advice, as this combination may increase your risk of bleeding. Talk to your doctor to find a safe pain management plan.
Yes, Lyo-5 Tablet 10's is sometimes used to help reduce swelling in the airways and thin out thick mucus, making it easier to clear congestion from the sinuses and throat. Talk to your doctor to see if this is the right treatment for your respiratory symptoms.
If you develop a skin rash, hives, or any other signs of an allergic reaction, stop taking the medication immediately and contact your healthcare provider. Talk to your doctor to find an alternative treatment.
There is limited clinical safety data regarding the use of this medicine during pregnancy. It is generally not recommended unless clearly needed and prescribed by your healthcare provider. Talk to your doctor to evaluate the benefits and risks.
You should stop taking Lyo-5 Tablet 10's at least two weeks before any scheduled surgery or dental procedure to minimise the risk of excessive bleeding during or after the operation. Talk to your doctor or surgeon for specific instructions on when to stop and restart your medication.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Serrapeptase Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. ScienceDirect Topics. S181808761630160X - Research & Medical Applications Summary. Amsterdam, Netherlands: Elsevier; 2025. [Accessed on 02 Jun. 2026]Check here
  3. PubChem PubChem. [Accessed on 02 Apr. 2019]Check here
  4. Serratiopeptidase: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD [Internet]. Webmd.com. 2025 [Accessed on 5 December 2025]Check here
  5. Manju Tiwari. The role of serratiopeptidase in the resolution of inflammation. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in May 2017] [Accessed on 25th September 2025]Check here
  6. Ciplamed. MOVEXX SP Tablets [Revised in September 2023] [Accessed on 25th September 2025]Check here
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 02 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

H.No.12-1-325/2/3 ASIF NAGAR , HYDERABAD, Telangana, India - 500028
Other Info - LYO0050
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