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  2. Macdanib 150 Softgel Capsule 10's

Macdanib 150 Softgel Capsule 10's

Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Composition

NINTEDANIB-150MG

Consume Type

ORAL

In Stock

Prescription Required
Product Details

About Macdanib 150 Softgel Capsule 10's

Macdanib 150 Softgel Capsule 10's belongs to the category of 'anti-fibrotic medicine', and it is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.

Macdanib 150 Softgel Capsule 10's contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Macdanib 150 Softgel Capsule 10's helps in slowing down the progress of idiopathic pulmonary fibrosis.

Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Macdanib 150 Softgel Capsule 10's if you are pregnant or breastfeeding. Macdanib 150 Softgel Capsule 10's may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Macdanib 150 Softgel Capsule 10's as it could lead to increased dizziness. Macdanib 150 Softgel Capsule 10's is not recommended for children below 18 years as safety and effectiveness have not been established. Macdanib 150 Softgel Capsule 10's is listed as pregnancy category D. Because Macdanib 150 Softgel Capsule 10's can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Macdanib 150 Softgel Capsule 10's. Consult your doctor if you are breastfeeding; your doctor will decide whether the Macdanib 150 Softgel Capsule 10's can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Macdanib 150 Softgel Capsule 10's

Idiopathic pulmonary fibrosis

Medicinal Benefits

Macdanib 150 Softgel Capsule 10's is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Macdanib 150 Softgel Capsule 10's can help effectively slow the rate of lung function decline by 50%. Macdanib 150 Softgel Capsule 10's helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Macdanib 150 Softgel Capsule 10's helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Macdanib 150 Softgel Capsule 10's

  • Diarrhoea
  • Feeling and being sick
  • Tummy (Abdominal) Pain
  • Loss of appetite and weight loss

In-Depth Precautions and Warning

Drug Warnings

Do not use Macdanib 150 Softgel Capsule 10's if you are allergic to any components present in Macdanib 150 Softgel Capsule 10's. Macdanib 150 Softgel Capsule 10's is listed as pregnancy category D; because Macdanib 150 Softgel Capsule 10's can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Macdanib 150 Softgel Capsule 10's. Consult your doctor if you are breastfeeding; your doctor will decide whether the Macdanib 150 Softgel Capsule 10's can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Macdanib 150 Softgel Capsule 10's may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Macdanib 150 Softgel Capsule 10's as it could lead to increased dizziness. Macdanib 150 Softgel Capsule 10's is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug Interactions

Drug-Drug Interactions: Macdanib 150 Softgel Capsule 10's may have interaction with medicines used to treat fungal infections (e.g. ketoconazole), medications used to treat bacterial infections/CYP3A4 inhibitors (e.g. erythromycin), drugs that affect your immune system (e.g. cyclosporine), antibiotic medicines used to treat tuberculosis (e.g. rifampicin), medicines to treat seizures (e.g. carbamazepine, phenytoin), and herbal medicines to treat depression (e.g. St. John’s Wort).

Drug-Food Interactions: Avoid grapefruit juice and chargrilled meats.

Drug-Disease Interactions: Macdanib 150 Softgel Capsule 10's may interact with smoking and severe hepatic and end-stage renal impairment requiring dialysis.

Drug-Drug Interactions Checker List:

  • KETOCONAZOLE
  • ERYTHROMYCIN
  • CYCLOSPORINE
  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENYTOIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is not known if alcohol interacts with Macdanib 150 Softgel Capsule 10's. However, as a precautionary measure, you are recommended not to consume alcohol with the Macdanib 150 Softgel Capsule 10's to avoid unpleasant side effects.

    • Safety Warning

      Pregnancy

      unsafe

      Macdanib 150 Softgel Capsule 10's is listed as pregnancy category D. Because Macdanib 150 Softgel Capsule 10's can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Macdanib 150 Softgel Capsule 10's.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor if you are breastfeeding; your doctor will decide whether Macdanib 150 Softgel Capsule 10's can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      Macdanib 150 Softgel Capsule 10's may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Macdanib 150 Softgel Capsule 10's is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Macdanib 150 Softgel Capsule 10's is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

    • Safety Warning

      Children

      caution

      Macdanib 150 Softgel Capsule 10's is not recommended for children below 18 years as safety and effectiveness have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
    • Exercise moderately. Eat healthily.
    • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
    • Quit smoking and alcohol.
    • Get ample rest.
    • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
    • Lean proteins such as fish, meat, and poultry are the best.
    • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
    • Avoid processed and refined foods.

    Special Advise

    • Regular blood tests and occasional tests of your bone marrow will be carried out to check whether the treatment is working. If it does work, it will usually be taken for life.

    Other Information (MAC0415)

    This item is Not Returnable.

    Expires on or after - Sep-23

    Patients Concern

    Disease/Condition Glossary

    Idiopathic pulmonary fibrosis (IPF): Idiopathic pulmonary fibrosis belongs to a group of interstitial lung diseases. It is an irreversible chronic disease marked by a progressive decline in lung function. The tissues in the lungs become inflamed and scarred over time, due to which it gets difficult to breathe properly. The scar tissue, known as fibrosis, becomes thick /stiff over time, making it hard for the lungs to work efficiently. This causes decreased lung function, which leads to increased breathlessness and coughing. Breathing difficulties can lead to other medical problems. Symptoms of IPF are shortness of breath, persistent dry cough, loss of appetite, weight loss, and rounded and widened tips of the fingers and toes.

    FAQs

    Macdanib 150 Softgel Capsule 10's helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.

    Avoid smoking before starting the treatment while taking Macdanib 150 Softgel Capsule 10's as smoking might alter the effectiveness of Macdanib 150 Softgel Capsule 10's.

    Macdanib 150 Softgel Capsule 10's should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking Macdanib 150 Softgel Capsule 10's until your doctor asks you to stop it.

    If you have any surgery, including dental surgery, please inform your doctor if you are taking Macdanib 150 Softgel Capsule 10's as your doctor might stop Macdanib 150 Softgel Capsule 10's before undergoing surgery.

    In elderly patients, the risk of side effects is more if you are taking Macdanib 150 Softgel Capsule 10's. For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

    Idiopathic pulmonary fibrosis is treated with Macdanib 150 Softgel Capsule 10's (IPF; scarring of the lungs with an unknown cause). It's also used to treat fibrosing interstitial lung disorders.

    PRODUCT SUBSTITUTES

    Macdanib 150 Softgel Capsule 10's

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    (Inclusive of all taxes)

    Provide Delivery Location

    Strip

    1

    10 Capsule in 1 Strip