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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Macgest 200 Capsule is used to treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. It contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body. This medicine may sometimes cause side effects such as dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes or constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Whats That

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Composition :

PROGESTERONE-200MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Macgest 200 Capsule

Macgest 200 Capsule is used in combination with oestrogen for hormone replacement therapy. Besides this, Macgest 200 Capsule also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Macgest 200 Capsule contains progesterone, which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take Macgest 200 Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of Macgest 200 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, Macgest 200 Capsule or any other medicines, please tell your doctor. Avoid taking Macgest 200 Capsule if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking Macgest 200 Capsule if you are pregnant, as it may harm the unborn baby. You are advised to use effective birth control methods while taking Macgest 200 Capsule to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Macgest 200 Capsule . Drive only if you are alert, as Macgest 200 Capsule may cause drowsiness or dizziness.

Uses of Macgest 200 Capsule

Macgest 200 Capsule is used in the treatment of female infertility and female hormonal imbalance. The detailed uses of Macgest 200 Capsule are as follows:
• Hormonal Replacement Therapy: Macgest 200 Capsule is commonly used in women undergoing hormonal replacement therapy to manage symptoms associated with menopause or hormonal imbalances.
• Luteal Phase Support: Macgest 200 Capsule is prescribed to support the luteal phase during assisted reproductive technologies like in vitro fertilization (IVF), increasing the chances of pregnancy.
• Menstrual Disorders: Macgest 200 Capsule helps regulate the menstrual cycle and manage symptoms related to irregular menstruation.
• Endometrial Preparation: Macgest 200 Capsule aids in preparing the endometrium for implantation during fertility treatments, ensuring an optimal environment for a fertilized egg.
• Prevention of Miscarriage: In some cases, Macgest 200 Capsule is recommended for pregnant women with a history of recurrent miscarriages to help maintain the pregnancy and provide support during its early stages.

Directions for Use

Take Macgest 200 Capsule as prescribed by your doctor. Swallow it with a glass of water. Do not break, crush or chew it. It is best to take Macgest 200 Capsule at bedtime as it may cause dizziness or drowsiness.

Medicinal Benefits

Macgest 200 Capsule contains Progesterone that is used in combination with oestrogen for hormone replacement therapy. Also, Macgest 200 Capsule is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). Macgest 200 Capsule replaces oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms. Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.

How Macgest 200 Capsule Works

Macgest 200 Capsule contains progesterone, which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

Storage

Store in a cool and dry place away from sunlight
Side effects of Macgest 200 Capsule
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Mood swings can be managed but cannot be controlled. Therefore, spending time in nature can help you feel light and improve your mood.
  • Practice meditation, deep breathing and do regular exercise that can positively affect your mood. Also helps in processing the situation before responding to it.
  • Food has direct impact on mood. Therefore, eat foods that are less processed and reduce sugar intake.
  • Consult your doctor if the mood swings are uncontrollable or unmanageable.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
  • Talk to your doctor to determine the underlying cause of bleeding between periods and discuss appropriate treatment options.
  • To avoid infection, use sanitary items and change them frequently as part of proper hygiene.
  • Engage in moderate exercise, like walking, cycling, or swimming, to help regulate your menstrual cycle.
  • To lower the chance of hormonal imbalances and intermenstrual bleeding, maintain a healthy weight.
  • Apply a warm compress to the lower abdomen to ease cramps.
  • Seek medical attention if you experience heavy or prolonged bleeding between periods.

What if I have taken an overdose of Macgest 200 Capsule

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

If you are allergic to soya, Macgest 200 Capsule or any other medicines, please tell your doctor. Avoid taking Macgest 200 Capsule if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking Macgest 200 Capsule if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking Macgest 200 Capsule to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Macgest 200 Capsule . Drive only if you are alert as Macgest 200 Capsule may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking Macgest 200 Capsule . If you are about to undergo any surgery, please inform your doctor that you are taking Macgest 200 Capsule .

Drug-Drug Interactions

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ProgesteroneVenetoclax
Severe
ProgesteroneEdoxaban
Severe

Drug-Drug Interactions

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ProgesteroneVenetoclax
Severe
How does the drug interact with Macgest 200 Capsule:
Co-administration of Macgest 200 Capsule with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Macgest 200 Capsule and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneEdoxaban
Severe
How does the drug interact with Macgest 200 Capsule:
When Macgest 200 Capsule is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Macgest 200 Capsule and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Macgest 200 Capsule:
Co-administration of Macgest 200 Capsule with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Macgest 200 Capsule can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ProgesteroneTirzepatide
Moderate
How does the drug interact with Macgest 200 Capsule:
Macgest 200 Capsule may interfere with blood glucose control and reduce the effectiveness of tirzepatide and other diabetic medications.

How to manage the interaction:
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Monitor your blood sugar levels closely.

Drug-Food Interactions

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PROGESTERONE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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PROGESTERONE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grape fruit and its products may interact with Macgest 200 Capsule Avoid Grape fruit and its products during treatment with Macgest 200 Capsule

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.

  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.

  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.

  • Try to be stress-free to improve your mood swings due to hormonal fluctuations.

  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES
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Alcohol

Caution

Interaction of Macgest 200 Capsule with alcohol is unknown. Please consult a doctor before consuming alcohol while using Macgest 200 Capsule .

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Pregnancy

Caution

Macgest 200 Capsule supports pregnancy and helps in the maintenance of pregnancy. However, please consult a doctor if you are pregnant before taking Macgest 200 Capsule .

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Breast Feeding

Caution

Macgest 200 Capsule may be excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Macgest 200 Capsule may cause dizziness or drowsiness. Therefore, avoid driving if you feel dizzy or drowsy after taking Macgest 200 Capsule .

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Liver

Caution

Please consult a doctor if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Macgest 200 Capsule should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Macgest 200 Capsule is not recommended for children.

Have a query?

FAQs

Macgest 200 Capsule is used in combination with oestrogen for hormone replacement therapy. Besides this, Macgest 200 Capsule also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.

Macgest 200 Capsule contains Progesterone that works by replacing oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.

Macgest 200 Capsule may increase the risk of blood clots especially in patients with a history of blood clots. However, if you experience sudden chest pain, difficulty in breathing or painful swelling and redness of legs, stop taking Macgest 200 Capsule and consult a doctor immediately as these might be signs of blood clot.

If oestrogen is used alone for hormone replacement therapy, it may increase the risk of endometrial hyperplasia (excessive thickening of uterus lining) and endometrial cancer (cancer of the womb). Oestrogen in combination with Macgest 200 Capsule reduces this risk.

You are recommended to inform your doctor that you are taking Macgest 200 Capsule as you may need to stop taking Macgest 200 Capsule 4 to 6 weeks before surgery to decrease the risk of blood clot.

Macgest 200 Capsule may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.

Macgest 200 Capsule is not a contraceptive. You are recommended to use additional contraceptive methods to prevent pregnancy while taking Macgest 200 Capsule .

Macgest 200 Capsule should be swallowed as a whole with water. Do not crush or chew it.

Macgest 200 Capsule is a hormone extracted from plants and is chemically identical to human progesterone.

Yes, Macgest 200 Capsule can be taken daily. Usually, it is taken once everyday in the evening or at bedtime.

Some people might gain weight due to other reasons while taking Macgest 200 Capsule . Consult the doctor if you notice weight gain during Macgest 200 Capsule therapy.

Yes, Macgest 200 Capsule is safe if taken in the dose and duration prescribed by the doctor.

Progesterone plays a vital role in fertility. It improves the chances of becoming and staying pregnant by preparing the uterus lining.

Macgest 200 Capsule may cause side effects like dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. If the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MAC0085

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