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  1. Home
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  3. Macorate CR 200 Tablet 10's

Macorate CR 200 Tablet 10's, Pack of 10 TabletS
Macorate CR 200 Tablet 10's, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Macorate CR 200 Tablet is an anticonvulsant medication used in the treatment of severe epileptic seizures/fits, bipolar disorder, and migrane. This medicine works by decreasing the abnormal electrical activity in the brain and thus reduces seizures. Common side effects include sleepiness, dizziness, nausea, headache, and weakness.
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Composition :

MAGNESIUM VALPROATE-200MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Macorate CR 200 Tablet

Macorate CR 200 Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Macorate CR 200 Tablet also treats bipolar disorder and prevents migraine symptoms (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

The Macorate CR 200 Tablet contains 'Magnesium valproate', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. Macorate CR 200 Tablet increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thereby helping treat bipolar disorder.

Always use this medicine exactly as your doctor has told you or as per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. Sometimes, you may experience certain common side effects, such as stomach pain, nausea, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Macorate CR 200 Tablet without consulting your doctor to avoid worsening seizures. Do not take Macorate CR 200 Tablet if you are pregnant, as it could cause severe congenital disabilities. If you are of childbearing age, use effective contraception while taking Macorate CR 200 Tablet . Consult your doctor before taking Macorate CR 200 Tablet if you are breastfeeding. Do not drive or operate machinery as Macorate CR 200 Tablet causes drowsiness and dizziness. Avoid consuming alcohol with Macorate CR 200 Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Macorate CR 200 Tablet

Treatment of Bipolar disorder or epilepsy and migraine

Directions for Use

• Macorate CR 200 Tablet should be taken with or after food.• Macorate CR 200 Tablet is usually taken once or twice a day, or as prescribed by your doctor.• Swallow Macorate CR 200 Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Macorate CR 200 Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Additionally, Macorate CR 200 Tablet also treats bipolar disorder and prevents migraine headaches. Macorate CR 200 Tablet decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures. Macorate CR 200 Tablet is used to treat both localized (seizures that affect only a part of the brain) and generalized seizures (seizures that affect the entire brain).

How Macorate CR 200 Tablet Works

Macorate CR 200 Tablet contains 'Magnesium valproate', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. Macorate CR 200 Tablet increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thereby helping treat bipolar disorder.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Macorate CR 200 Tablet out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Macorate CR 200 Tablet
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.

What if I have taken an overdose of Macorate CR 200 Tablet

Take Macorate CR 200 Tablet only as prescribed by the physician. Do not exceed the recommended dose as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Macorate CR 200 Tablet if you are hypersensitive to 'Magnesium valproate or any ingredients in Macorate CR 200 Tablet . If you have liver problems, porphyria, urine-related problems (such as urea cycle disorder), diabetes, immune system disorder, or kidney problems, you should not take the Macorate CR 200 Tablet . Contact your doctor immediately if you have suicidal thoughts while taking Macorate CR 200 Tablet . Do not take Macorate CR 200 Tablet if you are pregnant as it is pregnancy category D medicine and can cause severe congenital disabilities. Macorate CR 200 Tablet enters into breast milk in trace amounts, but it is unlikely to harm your baby, so you can continue nursing if your doctor advises you to. Macorate CR 200 Tablet causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Macorate CR 200 Tablet as it could lead to increased dizziness and sleepiness. If you stop taking your medicine without consulting your doctor, your symptoms may worsen.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Adolescents and adults are advised to follow the Atkins diet (high fat, low carbohydrate).
  • Exercising on a regular basis aids with weight maintenance and general health.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can help reduce stress, reduce pain sensitivity, and increase coping abilities.
  • Have a seizure response plan in place, and make sure everyone around you knows what to do in the event of a seizure.
  • Prepare your living environment; simple changes may help reduce the risk of physical damage during a seizure.
  • Understand what causes seizures and try to reduce or avoid them.
  • Please keep your overall health in mind, as it can aid in the reduction of seizure activity.
  • Install an alarm or an emergency gadget to summon help during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Macorate CR 200 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consumption of alcohol while taking Macorate CR 200 Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Unsafe

Macorate CR 200 Tablet belongs to pregnancy category D. Avoid taking Macorate CR 200 Tablet if you are pregnant, as it could lead to severe birth defects.

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Breast Feeding

Caution

Macorate CR 200 Tablet may pass into breastmilk. Consult your doctor before taking Macorate CR 200 Tablet if you are breastfeeding.

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Driving

Unsafe

Macorate CR 200 Tablet causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Should not use the Macorate CR 200 Tablet if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

May need dose adjustment in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Macorate CR 200 Tablet can be given to children if prescribed by the doctor. The doctor will adjust the dose depending on the child's body weight.

Have a query?

FAQs

Macorate CR 200 Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Macorate CR 200 Tablet also treats bipolar disorder and prevents migraine symptoms (like a headache).

Macorate CR 200 Tablet decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizure episodes.

Macorate CR 200 Tablet helps treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Adults aged 18 and above can take it to prevent migraines. Macorate CR 200 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition that is characterized by intense headaches.

Macorate CR 200 Tablet may also be effective as an acute treatment option for headaches such as migraines, tension headaches, and cluster headaches. It should, however, only be used under the supervision of a doctor.

Macorate CR 200 Tablet is safe if taken in the dose and for the term prescribed by your doctor. Take it exactly as directed, and do not miss any doses. Follow your doctor's instructions carefully and notify him or her if any of the adverse effects bother you.

Macorate CR 200 Tablet does not cure epilepsy, however, it helps to prevent seizures. You may need to continue taking it for several years. It’s important not to stop taking it suddenly. Take it as directed by your doctor.

Do not stop taking Macorate CR 200 Tablet without consulting your doctor as stopping it suddenly can cause the symptoms to reoccur or worsen your condition. If you experience any difficulty while taking Macorate CR 200 Tablet , consult your doctor.

You may gain weight after using Macorate CR 200 Tablet as it is one of its side effects. To control weight, you need to make changes in your diet and lifestyle. Exercise regularly. Have a balanced diet and avoid alcohol consumption. Consult a doctor if you have any other concerns.

Macorate CR 200 Tablet doesn’t affect the working of birth control pills, but contraceptives may reduce its effectiveness, and seizures may reoccur. Inform your doctor if you are on birth control pills, so they can monitor your response to the treatment and check the levels of Macorate CR 200 Tablet in your blood.

Macorate CR 200 Tablet may cause hair thinning, changes in colour or texture of hair and even hair loss. Consult your doctor if you have any concerns regarding this. The hair growth will be noticed after either reducing the dose of Macorate CR 200 Tablet or using a different remedy for the hair loss.

Macorate CR 200 Tablet may cause side effects such as stomach pain, diarrhoea, dry or sore mouth, swollen gums, headache, weight gain, thinning hair, delayed or irregular periods, unusual eye movements and changes in colour or texture of hair. Consult the doctor if these persist longer.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - MAC0097

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 9:24 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://cdscoonline.gov.in/CDSCO/Drugs
  2. https://www.hindawi.com/journals/isrn/2014/412704/
  3. https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-children-born-mothers-who-took-valproate-products-while-pregnant-may
  4. https://www.nhs.uk/medicines/valproic-acid/#:~:text=Valproic%20acid%20is%20not%20recommended%20in%20pregnancy%2C%20as%20it%20can,the%20valproate%20pregnancy%20prevention%20programme

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