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  3. Mahagesic-MR4 Capsule 10's

Mahagesic-MR4 Capsule 10's, Pack of 10 CapsuleS
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Composition :

DICLOFENAC-50MG + THIOCOLCHICOSIDE-4MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mahagesic-MR4 Capsule

Mahagesic-MR4 Capsule is a combination medication primarily used to reduce and relieve pain due to muscle spasms (painful muscular contractions) associated with degenerative vertebral disorders, torticollis (neck muscle contractions), and upper and lower back pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Mahagesic-MR4 Capsule is a combination of two drugs: Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This helps reduce muscle stiffness and improves muscle movements, thereby relieving pain due to muscle spasms.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Mahagesic-MR4 Capsule include nausea, vomiting, loss of appetite, stomach pain, diarrhoea, and heartburn. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.

Before starting Mahagesic-MR4 Capsule , inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), autoimmune diseases (systemic lupus erythematosus), and smoking habit. Mahagesic-MR4 Capsule is not recommended for pregnant and breastfeeding women. Mahagesic-MR4 Capsule should not be given to children and adolescents below 18 years of age as safety has not been established. Avoid consuming alcohol while undergoing treatment with Mahagesic-MR4 Capsule . 

Uses of Mahagesic-MR4 Capsule

Treatment of Pain due to muscle spasms.

Directions for Use

• Mahagesic-MR4 Capsule can be taken with food to prevent stomach upset, or as directed by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Mahagesic-MR4 Capsule as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Mahagesic-MR4 Capsule treats pain due to muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (NSAIDs) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes that further prevents the formation of chemical messengers called 'prostaglandins (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This helps reduce muscle stiffness and improves muscle movements, thereby relieving pain due to muscle spasms.

How Mahagesic-MR4 Capsule Works

Mahagesic-MR4 Capsule is a combination of two drugs: Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This helps reduce muscle stiffness and improves muscle movements, thereby relieving pain due to muscle spasms.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Mahagesic-MR4 Capsule

Take Mahagesic-MR4 Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), autoimmune diseases (systemic lupus erythematosus), and smoking habit. Please consult your doctor before starting Mahagesic-MR4 Capsule if you have high cholesterol, chickenpox, porphyria (rare inherited disorder), hereditary disorders like Lapp lactase deficiency (lactose intolerance), galactose intolerance, glucose-galactose malabsorption (small intestines not being able to absorb and use glucose and galactose), fits, and blood clotting disorders. Do not take any other NSAIDs for pain relief along with Mahagesic-MR4 Capsule unless prescribed. Stop taking Mahagesic-MR4 Capsule and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Mahagesic-MR4 Capsule is not recommended for pregnant and breastfeeding women. Mahagesic-MR4 Capsule may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol while being treated with Mahagesic-MR4 Capsule . This medicine is not recommended in children and adolescents below 18 years of age as safety and efficacy are not established.

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching, reducing spasm, tear and sprain incidence. Mild exercises, such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful to ease the pain.
  • Avoid wearing tight-fitting clothes; wear loose garments for proper blood circulation.
  • Rest well and get plenty of sleep.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice or hot pack on the muscle for 15-20 minutes.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

Therapeutic Class

MUSCLE RELAXANTS

Mahagesic-MR4 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Mahagesic-MR4 Capsule to avoid the risk of adverse effects.

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Pregnancy

Unsafe

Mahagesic-MR4 Capsule is not recommended during pregnancy since it may harm the developing baby. Please consult your doctor for more information.

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Breast Feeding

Unsafe

Mahagesic-MR4 Capsule is not recommended during breastfeeding as it may be excreted in breast milk and cause adverse effects in the baby. Please consult your doctor if you are a nursing mother.

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Driving

Caution

Mahagesic-MR4 Capsule may make you feel dizzy, sleepy and can cause vision problems sometimes. Do not drive or operate machinery if you experience dizziness or drowsiness.

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Liver

Caution

Please consult your doctor since Mahagesic-MR4 Capsule should be used with caution in patients with liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor since Mahagesic-MR4 Capsule should be used with caution in patients with kidney impairment/kidney disease.

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Children

Unsafe

Mahagesic-MR4 Capsule is not recommended in children and adolescents younger than 18 years of age.

Have a query?

FAQs

Mahagesic-MR4 Capsule is used to reduce and relieve pain due to muscle spasms (painful muscular contractions) associated with degenerative vertebral disorders, torticollis (neck muscle contractions), and upper and lower back pain.

Mahagesic-MR4 Capsule contains Diclofenac and Thiocolchicoside. Diclofenac works by blocking the action of certain chemical messengers that cause pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that relieves muscle stiffness due to muscle spasms and improves muscle movements.

Mahagesic-MR4 Capsule is usually prescribed for a short period and can be discontinued if there is no pain. To treat your condition effectually, continue taking Mahagesic-MR4 Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Mahagesic-MR4 Capsule .

Diarrhoea can be a side-effect of Mahagesic-MR4 Capsule . Drink enough fluids and eat fibre rich food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.

It is not advised to use other NSAIDs or pain killers while using Mahagesic-MR4 Capsule . Please seek medical advice for further information.

You are not recommended to take Mahagesic-MR4 Capsule with warfarin as simultaneous use of these two medicines may increase the bleeding risk. However, if you are supposed to use these medicines together, please contact your doctor so that the dose may be adjusted or you may be prescribed alternate medicine.

Common side effects of Mahagesic-MR4 Capsule include nausea, vomiting, loss of appetite, stomach pain, diarrhoea, and heartburn. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.

Yes, Mahagesic-MR4 Capsule is a painkiller used to relieve pain due to muscle spasms associated with degenerative vertebral disorders, torticollis (neck muscle contractions), and upper and lower back pain.

Yes, Mahagesic-MR4 Capsule can be used to relieve upper and lower back pain if advised by the doctor. It inhibits chemical messengers that cause pain and reduces muscle stiffness.

Mahagesic-MR4 Capsule is contraindicated in people who are allergic to any of its components. It is also not recommended for people having stomach ulcers and stomach bleeding with NSAID use.

Store Mahagesic-MR4 Capsule at room temperature, in a dry place. Keep it out of sight and reach of children.

Mahagesic-MR4 Capsule may cause dizziness sometimes. Do not drive or operate machinery if you experience dizziness.

Long-term use of Mahagesic-MR4 Capsule may cause kidney damage. Therefore, avoid long-term use and take it only for the duration recommended by the doctor.

No, taking a higher than the recommended dose of Mahagesic-MR4 Capsule would not be more effective but may lead to unpleasant side effects. Therefore, take Mahagesic-MR4 Capsule only as per the dose advised by the doctor.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase 3, New Delhi - 110020.
Other Info - MAH0055

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:51 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.2660.pdf
  2. https://www.ema.europa.eu/en/documents/referral/thiocolchicoside-article-31-referral-annex-iii_en.pdf
  3. https://iasispharma.com/wp-content/uploads/pdf/RELIEF_PIL_ENG.pdf
  4. https://www.sanofi.in/-/media/Project/One-Sanofi-Web/Websites/Asia-Pacific/Sanofi-IN/Home/science-and-innovation/for-healthcare-professionals/product-information/Myoril.pdf?la=en
  5. https://www.drugs.com/diclofenac.html

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