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compositionComposition:SULBACTAM-100MG
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Prescription Medicine
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Matabac 1Gm Inj is used in the treatment of moderate to severe bacterial infections. It contains Sulbactam, which works by blocking the beta-lactamase produced by the bacteria to inactivate antibiotic medicines. Common side effects of this medication include diarrhoea, nausea, vomiting, fatigue, and headache.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SULBACTAM-100MG

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Matabac 1Gm Inj

Matabac 1Gm Inj is a medicine given by injection to help treat severe bacterial infections in various parts of the body. It works by shielding partner antibiotics from being broken down by bacteria, allowing the infection to be cleared effectively. This medication is always used in combination with an antibiotic, as it does not kill bacteria on its own but rather makes the antibiotic work much better.

Because this medication is injected directly into a vein or muscle, it is usually taken at regular intervals throughout the day to keep a steady level in your body. While you are receiving this treatment, staying well-hydrated and getting plenty of rest can help support your body's immune system. Eating simple, nutrient-rich foods can also help your digestive system recover during therapy.

Some people may experience mild side effects, such as pain or swelling at the injection site, or mild diarrhoea. If you develop severe watery diarrhoea, a high fever, or signs of a serious allergic reaction, you should contact your doctor immediately. Do not ignore these symptoms, as severe diarrhoea can indicate a serious bowel condition that requires prompt medical attention.

Do not take this if you have had a severe allergic reaction to similar antibiotics, such as penicillins or cephalosporins, in the past. Before starting this treatment, tell your doctor if you have kidney disease, asthma, or a history of multiple allergies, as your dosing schedule may need to be adjusted. Talk to your doctor or pharmacist if you are unsure whether this medication is safe for you.

This medicine can interact with certain gout medications, which can cause the level of the drug to rise in your body, so always share your full medication list with your healthcare team. If you are pregnant, breastfeeding, or an older adult, consult your doctor to ensure this treatment is safe for your specific needs, as special precautions or monitoring may be required.

Uses of Matabac 1Gm Inj

A healthcare professional may prescribe Matabac 1Gm Inj to help treat serious bacterial infections alongside other antibiotics. These include:

  • Severe abdominal infections: Matabac 1Gm Inj helps clear deep-seated infections in the stomach or intestines by stopping bacterial defences and allowing co-administered antibiotics to destroy the bacteria.
  • Skin and soft tissue infections: It works to support partner antibiotics in healing deep skin, muscle, and wound infections.
  • Gynecological infections: It helps treat infections of the female reproductive organs by preventing bacteria from resisting the primary antibiotic treatment.
  • Respiratory tract infections: It assists in clearing severe bacterial infections in the lungs, such as severe bacterial pneumonia.

Key Benefits

Matabac 1Gm Inj helps restore the effectiveness of certain antibiotics, allowing them to work better against serious bacterial infections. Key benefits include:

  • Restores antibiotic effectiveness: The primary benefit of Matabac 1Gm Inj is its ability to restore the power of other antibiotics when they would otherwise fail. By neutralising the defence systems that bacteria use to protect themselves, it ensures your main antibiotic treatment can destroy the bacteria successfully.
  • Supports faster recovery: This protection leads to a faster recovery from severe, life-threatening infections, helping to reduce the overall time you need to spend in the hospital.
  • Relieves infection symptoms: It also helps relieve the painful and uncomfortable symptoms of infection, such as fever, swelling, and localised pain, allowing you to start feeling better sooner.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Matabac 1Gm Inj will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Matabac 1Gm Inj Works

Matabac 1Gm Inj contains sulbactam, some bacteria produce special defence proteins called beta-lactamases, which act like shields by destroying certain antibiotics before they can kill the bacteria, causing the treatment to fail. Matabac 1Gm Inj works as a beta-lactamase inhibitor, acting as a decoy that binds tightly to these bacterial defence proteins and permanently disables them, neutralising these protective shields and allowing the co-administered antibiotic to safely enter the bacteria and destroy them from within.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Matabac 1Gm Inj. Please consult a doctor.

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Pregnancy

Caution

Matabac 1Gm Inj should be used during pregnancy only if clearly needed.

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Breast Feeding

Caution

Caution should be exercised when Matabac 1Gm Inj is administered to a nursing mother.

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Driving

Consult your doctor

It is unknown if Matabac 1Gm Inj alters your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Matabac 1Gm Inj.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving Matabac 1Gm Inj.

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Children

Safe if prescribed

Matabac 1Gm Inj is safe for children if prescribed by a doctor. The dose and duration will be determined by the doctor.

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Heart

Caution

Matabac 1Gm Inj may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Matabac 1Gm Inj.

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Geriatrics

Safe if prescribed

Matabac 1Gm Inj is generally considered safe when used under medical supervision in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Matabac 1Gm Inj

If you suspect an overdose, seek immediate emergency medical attention. Overdose symptoms can include muscle twitching, muscle spasms, seizures, or extreme confusion.

Diet & Lifestyle Advise

  • Take probiotics: Since antibiotics can disrupt your healthy gut bacteria, taking a probiotic supplement a few hours after your injection can help prevent mild diarrhoea and support gut health.
  • Stay hydrated: Drink plenty of water throughout the day. This helps your kidneys process and clear the medicine from your bloodstream efficiently.
  • Rest thoroughly: Allow your body to rest as much as possible, which preserves energy and helps your immune system fight off the infection.
  • Eat nutrient-dense foods: Focus on easily digestible, protein-rich, and vitamin-rich meals to support tissue repair and overall recovery during your treatment.
  • Children: The dose is carefully calculated according to the child's age, weight, and type of infection. Always use this medicine exactly as prescribed.
  • Older adults: Older adults, especially those with reduced kidney function, may require dose adjustments and closer monitoring during treatment.
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How Soon It Starts Working

The time required for Matabac 1Gm Inj to start to work: Matabac 1Gm Inj ideally shows its action within 15-30 minutes of administration. The time for which the effects of Matabac 1Gm Inj last: The duration of Matabac 1Gm Inj effect is unknown.

What if you forget to take Matabac 1Gm Inj

If you receive this medicine in a hospital or clinic, missing a dose is highly unlikely. If you are injecting it at home and miss a dose, inject it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular schedule. Do not inject a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure.

Storage

• Store dry, unmixed vials of Matabac 1Gm Inj at room temperature, between 20°C and 25°C.

Drug Warnings

  • Check the liquid: Always inspect the mixed solution before injecting. Do not use it if it contains visible particles, looks cloudy, or is discolored.
  • Complete the full schedule: Finishing your entire prescription is critical, even if you feel completely healthy after a few days. Stopping early can allow the remaining bacteria to multiply and become resistant.
  • Never reuse needles: Always use sterile, single-use syringes and needles. Safely discard them in a puncture-proof sharps container immediately after use to prevent accidental needle sticks.
  • Monitor your skin: Watch the injection sites closely. If you notice signs of skin infection, such as worsening redness, warmth, pus, or severe tenderness, contact your doctor right away.

Drug-Drug Interactions

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  • Probenecid: This medication can slow down how fast your kidneys remove Matabac 1Gm Inj from your body, which can increase the level of the medicine in your blood and raise the risk of side effects.
  • Aminoglycosides: Mixing these antibiotics in the same IV bag or syringe with Matabac 1Gm Inj can make both medications less effective. They should be injected at different times and through separate lines.
  • Warfarin: Antibiotic treatment may alter the effect of warfarin and increase the risk of bleeding. Your doctor may monitor your blood clotting (INR) more closely during treatment.
  • Hormonal contraceptives: Broad-spectrum antibiotics may reduce the effectiveness of hormonal contraceptives in some people. Discuss whether you need additional contraceptive protection during treatment.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Matabac 1Gm Inj when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Matabac 1Gm Inj is used to treat Bacterial infections.
Matabac 1Gm Inj works by blocking beta-lactamase that is produced by the bacteria to inactivate antibiotic medicines.
Diarrhoea might be a side-effect of Matabac 1Gm Inj. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Concomitant use of probenecid with Matabac 1Gm Inj may increase and prolong the blood levels of sulbactam. Therefore, consult the doctor before taking probenecid during treatment with Matabac 1Gm Inj.
The common side effects of Matabac 1Gm Inj include diarrhoea, nausea, vomiting, fatigue, and headache. If these side effects persist, please inform your doctor.
Matabac 1Gm Inj is a beta-lactamase inhibitor that helps protect certain antibiotics from being broken down by resistant bacteria, making them more effective. It is commonly combined with antibiotics such as ampicillin or cefoperazone, depending on the type and severity of the infection. Your doctor will choose the most appropriate combination. Talk to your doctor.
Matabac 1Gm Inj should not be taken by individuals who are allergic to any of its components. It is also not recommended for patients with a history of severe allergic reactions to penicillin or cephalosporins. Please inform your doctor before taking Matabac 1Gm Inj with other antibiotics.
Before receiving Matabac 1Gm Inj, you should discuss any allergies you have, especially to the components of Matabac 1Gm Inj, penicillins, or other beta-lactam antibiotics. Inform your doctor if you have any existing infections, or if you are pregnant or breastfeeding. Also, let your doctor know if you are taking any prescription or over-the-counter medications, as well as any herbal or vitamin supplements.
No, you should avoid using a discoloured solution of Matabac 1Gm Inj. Discoloration may indicate contamination, which could reduce the drug's effectiveness. It is recommended to discard the solution and use a new vial.
No, continue taking Matabac 1Gm Inj as prescribed by your doctor, even if you start feeling better. Stopping the medication early may lead to incomplete treatment and may cause the bacteria to develop resistance to the antibiotics.
Alcohol does not directly stop Matabac 1Gm Inj from working, but it can dehydrate your body, weaken your immune system, and worsen side effects like stomach upset. It is best to avoid alcohol until you have fully recovered from your infection. Talk to your doctor.
Yes, if your doctor determines it is safe, you or a caregiver can be trained to inject Matabac 1Gm Inj at home. You must carefully follow the sterile preparation and injection instructions provided by your clinical team. Talk to your doctor.
Small amounts of this medicine may pass into breast milk, which can sometimes cause mild diarrhoea or yeast infections in a nursing baby. Your healthcare provider will weigh the benefits and risks before prescribing it. Talk to your doctor.
Some mild discomfort or redness is common. However, if the pain gets worse, or if you notice severe swelling, warmth, or pus, it could be a sign of a skin reaction or infection. Talk to your doctor.
Matabac 1Gm Inj is not absorbed well by the stomach when swallowed. Injecting it directly into a vein or muscle ensures that the full dose quickly enters your bloodstream to fight severe infections. Talk to your doctor.
Matabac 1Gm Inj is used to treat bacterial infections and does not work against viral infections such as the common cold, flu, or COVID-19. It should only be used when prescribed for a bacterial infection. Talk to your doctor.
If you miss a dose while administering at home, take it as soon as you remember. If your next dose is due within a few hours, skip the missed dose and resume your regular schedule. Do not double the dose. Talk to your doctor.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - MAT0088
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