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compositionComposition:MEFENAMIC ACID-500MG
prescription
Prescription Medicine
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Mef 500mg Tablet is used to provide relief from mild to moderate pain and inflammation associated with muscular, rheumatic, and arthritic disorders, headache, trauma, dental pain, and pain after surgery or childbirth. Additionally, it is used to relieve period pain and premenstrual syndrome symptoms (PMS) and manage excessively heavy periods. It contains Mefenamic acid, which works by blocking the effect of chemical messengers that cause pain and inflammation. In some cases, you may experience certain common side effects such as abdominal pain, nausea, vomiting, diarrhoea, heartburn and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MEFENAMIC ACID-500MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Mef 500mg Tablet

Mef 500mg Tablet is an oral medication widely prescribed to provide short-term relief from mild to moderate pain. It is clinically used to manage short-term pain such as dental pain, muscle aches, headaches, and menstrual cramps. By targeting the source of discomfort, this medicine helps you manage physical pain and restore normal daily function.

This medication is typically taken up to three times a day, but it should only be used consistently for the exact duration recommended by your doctor. It is highly recommended to take each dose with food or a glass of milk to protect your stomach lining from irritation. Making minor adjustments, such as using warm compresses for menstrual pain or avoiding excessive physical strain during recovery, can further support your progress.

While taking Mef 500mg Tablet, you may experience mild side effects like heartburn, nausea, or mild indigestion. However, if you experience rare but serious signs such as severe stomach pain, black stools, or unusual bleeding, you must stop taking the medication and consult your doctor immediately.

Before starting this medication, talk to your doctor if you have a history of high blood pressure, heart conditions, asthma, or kidney disease. Do not take this if you have active stomach ulcers, severe heart failure or if you have previously experienced severe allergic reactions like asthma or rashes after taking aspirin or similar pain relievers.

This medication can interact with other substances, such as blood thinners or alcohol, which may significantly increase your risk of stomach bleeding. If you are pregnant, breastfeeding, or an elderly individual, it is crucial to consult your doctor or pharmacist before using this medicine, as special precautions or alternative options may be required.

Uses of Mef 500mg Tablet

Mef 500mg Tablet is used to provide short-term relief from mild to moderate pain. The detailed uses of Mef 500mg Tablet are as follows:

  • Menstrual pain and heavy bleeding: Mef 500mg Tablet helps reduce severe pelvic cramping and manages heavy blood flow during your menstrual cycle.
  • Mild to moderate pain: It provides effective relief from short-term painful conditions, including toothaches, muscle strains, headaches, and pain after minor surgical procedures.
  • Joint and muscle inflammation: It helps ease discomfort, swelling, and stiffness caused by temporary inflammation in the joints or soft tissues.
     

Key Benefits

Mef 500mg Tablet helps relieve pain and inflammation, improving comfort and supporting recovery from a variety of painful conditions. In certain conditions, it may also help reduce excessive menstrual bleeding, providing comprehensive symptom relief.

  • Helps Relieve Pain and Inflammation: By reducing the production of substances that cause pain and inflammation, Mef 500mg Tablet helps relieve discomfort associated with injuries, dental procedures, musculoskeletal conditions, and other painful disorders.
  • Supports Comfort During Menstrual Periods: Mef 500mg Tablet helps reduce menstrual cramps and, where indicated, may also help decrease excessive menstrual bleeding, making periods more comfortable and manageable.
  • Improves Daily Comfort and Recovery: By effectively controlling pain, Mef 500mg Tablet helps improve mobility, supports better sleep, and allows you to carry out daily activities more comfortably while recovering from pain or inflammation.
     
Side effects of Mef 500mg Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Mef 500mg Tablet can be taken with food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Tablet/capsule: Swallow it as a whole with a glass of water.
  • Dispersible tablet: Dissolve the tablet in a glass of water and consume it immediately.
  • Do not break, chew, or crush it.

How Mef 500mg Tablet Works

Mef 500mg Tablet contains mefenamic acid. It belongs to a class of medications known as non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the action of specific enzymes in your body called cyclooxygenase (COX) enzymes. These enzymes are responsible for producing prostaglandins, which are natural chemicals that trigger pain, swelling, and inflammation at injury sites or during menstruation. By stopping the production of these chemicals, the medication effectively reduces both the pain signal and the swelling in the affected tissues.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mef 500mg Tablet as it may increase drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Mef 500mg Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Mef 500mg Tablet may pass into breastmilk. Consult your doctor if you are breastfeeding.

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Driving

Caution

Mef 500mg Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Please consult your doctor. Your doctor will recommend it based on your child's condition.

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Heart

Unsafe

Mef 500mg Tablet is not recommended for use in cardiac patients due to the cardiovascular effects.

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Geriatrics

Caution

Elderly patients may require caution and dose adjustments, as Mef 500mg Tablet may increase the risk of side effects.

What if I have taken an overdose of Mef 500mg Tablet

If you suspect an overdose, seek immediate emergency medical attention. Overdose symptoms may include severe stomach pain, extreme drowsiness, nausea, vomiting, or slowed breathing.

Diet & Lifestyle Advise

  • Drink plenty of fluids, especially water, throughout the day to support your kidneys and maintain optimal hydration while taking this medication.
  • Avoid drinking alcohol, as it can significantly increase the risk of stomach irritation, ulcers, and bleeding when combined with this medicine.
  • If you are taking this for menstrual pain, applying a warm heating pad to your lower abdomen can help relax your muscles and work alongside the medication to ease discomfort.
  • Eat small, frequent, and bland meals to protect your digestive tract and reduce the likelihood of experiencing an upset stomach or acid reflux.
     
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How Soon It Starts Working

The time required for Mef 500mg Tablet to start to work: The time required for Mef 500mg Tablet to start to work is 20 to 30 minutes after administration. The time for which the effects of Mef 500mg Tablet last: The effect of Mef 500mg Tablet lasts for 4 to 6 hours.

What if you forget to take Mef 500mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your normal schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Mef 500mg Tablet tablets or capsules at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medication inside its original blister pack or container to protect it from moisture and direct light.

Drug Warnings

  • Avoid taking this medication alongside other non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, naproxen, or high-dose aspirin, as this increases your risk of severe stomach issues.
  • Remain upright for at least 15 to 30 minutes after taking your dose to prevent oesophageal irritation or difficulty swallowing.
  • If you are scheduled for any surgical or dental procedures, inform your healthcare provider that you are taking this medication, as it may affect blood clotting.
  • If your doctor prescribes this medicine for more than a few days, attend all scheduled appointments for blood tests to monitor your kidney and liver function.
  • Stop taking the medication immediately at the first sign of a skin rash, skin peeling, or mouth sores, and contact your doctor right away.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (such as warfarin): May significantly increase the risk of serious stomach and intestinal bleeding.
  • Other NSAIDs or aspirin: Increases the likelihood of developing painful stomach ulcers or gastrointestinal bleeding.
  • Blood pressure medications (such as ACE inhibitors or beta-blockers): Mef 500mg Tablet can make these blood pressure drugs less effective and may increase the risk of kidney damage.
  • Lithium: May raise the levels of lithium in your blood to toxic levels, requiring close monitoring.
  • Diuretics (water pills): Can reduce their effectiveness and increase the strain on your kidneys.
     
Mefenamic acidMeloxicam
Critical
Mefenamic acidKetorolac
Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
How does the drug interact with Mef 500mg Tablet:
Co-administration of Mef 500mg Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Mef 500mg Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Mef 500mg Tablet:
Coadministration of Mef 500mg Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Mef 500mg Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidPrasugrel
Severe
How does the drug interact with Mef 500mg Tablet:
Co-administration of Mef 500mg Tablet with Prasugrel can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Mef 500mg Tablet with Prasugrel together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidCabozantinib
Severe
How does the drug interact with Mef 500mg Tablet:
Using cabozantinib together with Mef 500mg Tablet may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Mef 500mg Tablet and Cabozantinib, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like blood clotting problems, excessive bleeding, or severe headaches, it's best to contact a doctor right away. They can help address any complications and provide the necessary support. Do not stop using any medications without talking to a doctor.
Mefenamic acidLeflunomide
Severe
How does the drug interact with Mef 500mg Tablet:
Coadministration of Mef 500mg Tablet with Leflunomide can increase the risk or severity of liver disease.

How to manage the interaction:
Taking Mef 500mg Tablet with Leflunomide together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidDanaparoid
Severe
How does the drug interact with Mef 500mg Tablet:
Using danaparoid together with Mef 500mg Tablet can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possibility of interaction between Mef 500mg Tablet and Danaparoid, but it can be taken if prescribed by a doctor. If you notice any of these signs - bruising, swelling, vomiting, headache, dizziness, weakness, bleeding, or blood in your urine or stools, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Mefenamic acidEdoxaban
Severe
How does the drug interact with Mef 500mg Tablet:
Using Edoxaban together with Mef 500mg Tablet may increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Mef 500mg Tablet and Edoxaban together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, it's important to contact a doctor right away - problems with bleeding, dizziness, black or tarry stools, severe headache, weakness, or vomiting. Do not stop using any medications without talking to a doctor.
Mefenamic acidWarfarin
Severe
How does the drug interact with Mef 500mg Tablet:
Coadministration of Mef 500mg Tablet with Warfarin can increase the risk of bleeding.

How to manage the interaction:
Taking Mef 500mg Tablet with Warfarin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Mefenamic acidHuman immunoglobulin
Severe
How does the drug interact with Mef 500mg Tablet:
Taking Human immunoglobulin with Mef 500mg Tablet, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Mef 500mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Mefenamic acidDeferasirox
Severe
How does the drug interact with Mef 500mg Tablet:
Coadministration of Mef 500mg Tablet with Deferasirox can increase the risk or severity of gastric bleeding.

How to manage the interaction:
Taking Mef 500mg Tablet with Deferasirox together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Combined use greatly increases the risk of stomach bleeding and irritation of the stomach lining.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Mef 500mg Tablet is used to provide relief from mild to moderate pain and inflammation associated with muscular, rheumatic, and arthritic disorders, headache, trauma, dental pain, and pain after surgery or childbirth. Additionally, it is used to relieve period pain and premenstrual syndrome symptoms (PMS) and manage excessively heavy periods.
Mef 500mg Tablet works by blocking the chemical messengers that are responsible for pain and inflammation. Thereby, Mef 500mg Tablet provides relief from pain and inflammation.
Mef 500mg Tablet is generally prescribed for short-term use. Do not take Mef 500mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding.
Mef 500mg Tablet is used to relieve menstrual (period) pain, symptoms of premenstrual syndrome (PMS), and management of excessively heavy periods. Take only as prescribed by the doctor.
Avoid taking Mef 500mg Tablet if you have stomach ulcers. Mef 500mg Tablet might increase the risk of stomach ulcers, perforation of the stomach and intestinal bleeding with higher doses.
Diarrhoea might be a side-effect of Mef 500mg Tablet. Drink plenty of fluids and eat food rich in fibre. Consult your doctor if you experience excessive diarrhoea or if you find blood in stools.
It is considered harmful for patients with severe kidney problems and those experiencing active intravascular clotting, which obstructs blood flow due to blood clots.
Store Mef 500mg Tablet at room temperature, away from sunlight. Keep the Mef 500mg Tablet out of reach of children.
No, Mef 500mg Tablet doesn’t act as a contraceptive; it is used to relieve mild to moderate pain and inflammation.
Mef 500mg Tablet should be taken only as it is prescribed by the doctor. Do not self-medicate and do not recommend Mef 500mg Tablet to others with the same condition.
If the dose of Mef 500mg Tablet is missed, take the missed dose as soon as you remember. If it is time for the next dose, skip the missed dose and continue taking the regular dose. Avoid taking a double dose to make up for the missed one.
Mef 500mg Tablet is used for a short time, not more than 3-5 days of your menstrual cycle. However, the duration for your use will be advised by the doctor. Do not self-medicate.
It is highly recommended to take Mef 500mg Tablet with food or a glass of milk. Taking it on an empty stomach can increase the risk of stomach upset, indigestion, or irritation. If you still experience discomfort, talk to your doctor.
You should avoid taking Mef 500mg Tablet during pregnancy, particularly in the third trimester, as it can harm the unborn baby or cause complications during delivery. If you are pregnant or planning to become pregnant, talk to your doctor.
Taking Mef 500mg Tablet with paracetamol may occasionally be recommended by a doctor for short-term pain management, as they work differently. However, you should never combine pain relievers without professional advice. Talk to your doctor or pharmacist.
Yes, some people may experience drowsiness, dizziness, or lightheadedness while taking Mef 500mg Tablet. Avoid driving or operating machinery until you know how this medication affects you. If these symptoms persist, talk to your doctor.
It is highly advised to avoid drinking alcohol while taking Mef 500mg Tablet. Alcohol can significantly increase your risk of developing stomach ulcers or severe digestive tract bleeding. If you have concerns, talk to your doctor.

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Country of origin

India
Other Info - ME79350
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