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compositionComposition:MEFENAMIC ACID-50MG+PARACETAMOL-125MG
prescription
Prescription Medicine
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Mefi P Syrup is used for the treatment of pain, inflammation, migraine headache, period pain, heavy bleeding during periods, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis. The medicine provides effective pain relief and helps improve comfort in conditions involving inflammation and fever.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

MEFENAMIC ACID-50MG+PARACETAMOL-125MG

Manufacturer/Marketer :

Yaxon Biocare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Mefi P Syrup

Mefi P Syrup is an oral medication widely prescribed to treat mild to moderate pain, inflammation, and fever. It is commonly used to relieve discomfort from headaches, dental pain, muscle aches, and menstrual cramps. By targeting the source of pain and fever, this medicine helps you manage painful conditions and return to your daily activities.

This medication is typically taken only when needed for pain, or on a regular schedule as directed by your doctor for ongoing inflammatory conditions. Mefi P Syrup is generally recommended for short-term use, depending on the condition, unless your doctor advises otherwise. Always take it with food or a glass of milk to protect your stomach from irritation. Additionally, staying well-hydrated and resting the affected areas of your body can greatly enhance your recovery.

Some people may experience mild side effects while taking this medicine, such as nausea, mild stomach pain, or heartburn. If you experience severe symptoms like persistent stomach pain, dark stools, or yellowing of your skin and eyes, stop taking the medicine and consult your doctor immediately.

Before starting Mefi P Syrup, tell your doctor if you have a history of stomach ulcers, asthma, kidney issues, or heart problems. Do not take this if you have active bleeding in your stomach, severe heart failure, or a history of severe allergic reactions to pain relievers.

Taking this medication with alcohol increases the risk of stomach bleeding and liver damage, while smoking can aggravate stomach irritation. If you are pregnant, breastfeeding, or an elderly individual, consult your healthcare provider before taking Mefi P Syrup, as certain adjustments or precautions may be necessary.

Uses of Mefi P Syrup

Mefi P Syrup is used to treat pain, inflammation, osteoarthritis, and rheumatoid arthritis. The detailed uses of Mefi P Syrup are as follows:

  • Menstrual pain (dysmenorrhea): Mefi P Syrup helps reduce severe cramping and abdominal pain during menstrual cycles.
  • Dental pain: It relieves acute toothaches and swelling after dental procedures.
  • Muscle and joint pain: It reduces inflammation and pain caused by sprains, strains, or backaches.
  • Fever reduction: It helps lower high body temperature during infections or illnesses.
  • Headaches and migraines: It provides rapid relief from throbbing head pain.

Key Benefits

Mefi P Syrup helps relieve pain, reduce fever, and make it easier to carry out everyday activities more comfortably. It is commonly used for short-term relief of mild to moderate pain caused by conditions such as headaches, toothaches, muscle pain, joint pain, menstrual cramps, and fever.

Benefits may include:

  • Helps provide fast relief from mild to moderate pain.
  • Reduces fever and improves overall comfort during illness.
  • Helps ease pain and inflammation associated with muscles, joints, and soft tissues.
  • Improves comfort during menstrual cramps and other common painful conditions.
  • Supports better movement and daily functioning by reducing pain and stiffness.
  • Provides effective short-term relief to help you return to normal activities sooner.

Directions for Use

  • Take Mefi P Syrup exactly as prescribed by your doctor.
  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can increase stomach irritation.
  • Always take this medicine with or immediately after food to prevent an upset stomach.
  • Do not take more than the recommended dose or use it for longer than prescribed.

How Mefi P Syrup Works

Mefi P Syrup works through the combined action of two distinct active ingredients that target pain and fever in different ways. • Mefenamic acid: It acts as a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the chemical messengers in the body, known as prostaglandins, that cause pain, redness, and swelling. • Paracetamol: It is a pain reliever and fever reducer. It works primarily in the brain and central nervous system to block pain signals and adjust the body's temperature-regulating centre. • Together, these two ingredients provide effective relief from pain and fever, while the NSAID component also helps reduce swelling and inflammation.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mefi P Syrup as it may cause increased dizziness. It can also increase the risk of stomach bleeding.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant or have any concerns about this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult your doctor before taking Mefi P Syrup; your doctor will decide whether Mefi P Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

Mefi P Syrup may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Consult your doctor

Please consult your doctor. Your doctor will prescribe the dose and duration based on your child's condition.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed, extreme caution should be exercised.

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Geriatrics

Caution

Mefi P Syrup should be used with caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Mefi P Syrup

If you accidentally take too much Mefi P Syrup, seek emergency medical attention or contact a poison control centre immediately. Symptoms of an overdose may include severe nausea, vomiting, stomach pain, drowsiness, or difficulty breathing.

Diet & Lifestyle Advise

  • Avoid alcohol: Do not drink alcohol while taking this medicine, as it can increase the risk of stomach irritation and may put extra strain on your liver.
  • Stay upright after dosing: Remain sitting or standing for 15-30 minutes after taking the medicine to help reduce the chance of heartburn or irritation of the food pipe.
  • Choose smaller meals: Eat small, frequent meals instead of large, heavy ones to help reduce stomach discomfort while using this medicine.
  • Stay well hydrated: Drink plenty of fluids throughout the day to support healthy kidney function while taking pain-relieving medicines.
  • Check other medicines: Avoid taking other over-the-counter pain relievers or cold medicines without checking the ingredients, as they may contain the same active medicines and increase the risk of accidental overdose.
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How Soon It Starts Working

  • The time required for Mefi P Syrup to start to work: Mefi P Syrup ideally shows its action within 20 to 30 minutes after administration.
  • The time for which the effects of Mefi P Syrup last: The effect of Mefi P Syrup lasts for 12 hours.

What if you forget to take Mefi P Syrup

If you are taking Mefi P Syrup on a regular schedule and miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Check other medicines: Read the labels of your cold, cough, or pain medicines before taking them. Do not take other medicines containing paracetamol or similar pain relievers at the same time, as this can seriously harm your liver.
  • Watch for allergic reactions: Stop taking the medicine and get medical help immediately if you develop a skin rash, itching, or peeling skin. These may be early signs of a serious allergic reaction.
  • Avoid driving if affected: Do not drive, ride a bike, or operate machinery if you feel dizzy or sleepy after taking this medicine. Wait until you feel fully alert before doing these activities.
  • Tell your healthcare provider before procedures: Inform your doctor, dentist, or surgeon that you are taking this medicine before any planned procedure. It may affect how your blood clots during treatment.
  • Use the lowest effective dose: Taking this medicine in high doses or for a long time may increase the risk of a heart attack or stroke, especially if you already have heart disease. Take the lowest dose that works for you and use it only for the time recommended by your doctor.
  • Do not use in certain conditions: Do not take this medicine if you have a stomach ulcer or bleeding, severe kidney, liver, or heart disease, or if you are in the last three months of pregnancy.
  • Take extra care with certain health conditions: Tell your doctor before taking this medicine if you have asthma, high blood pressure, heart disease, a history of stomach ulcers, mild to moderate kidney or liver problems, or if you are older than 65 years. Your doctor may want to monitor you more closely during treatment.

Drug-Drug Interactions

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Drug-Drug Interactions:

  • Blood Thinners (e.g., warfarin): Taking these medicines alongside Mefi P Syrup may increase the risk of bleeding.
  • Other NSAIDs (e.g., aspirin, ibuprofen, naproxen): Taking these medicines with Mefi P Syrup may increase the risk of stomach ulcers and bleeding.
  • Blood Pressure Medicines (e.g., enalapril, furosemide): These medicines may become less effective and may increase the risk of kidney problems when taken with Mefi P Syrup.

Drug-Food Interactions:

  • Alcohol: Consuming alcohol while using this medicine significantly increases the risk of stomach irritation, bleeding, and liver damage.

Drug-Disease Interactions:

  • Asthma: This medicine may trigger asthma attacks or breathing difficulties in individuals who are sensitive to aspirin or other NSAIDs.
  • Stomach Ulcers or Bleeding: Those with active or past stomach ulcers should avoid this medication as it can worsen bleeding.
  • Liver or Kidney Disease: People with liver or kidney disease should use this medicine only under medical supervision. Dose adjustment, longer dosing intervals, or an alternative treatment may be needed, especially in chronic kidney disease or severe liver impairment.
Paracetamol + Mefenamic acidKetorolac
Critical
Paracetamol + Mefenamic acidEtodolac
Severe

Drug-Drug Interactions

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Paracetamol + Mefenamic acidKetorolac
Critical
How does the drug interact with Mefi P Syrup:
Coadministration of Mefi P Syrup with Ketorolac can increase the risk or severity of bleeding and ulcers.

How to manage the interaction:
Although there is an interaction between Mefi P Syrup and ketorolac, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidEtodolac
Severe
How does the drug interact with Mefi P Syrup:
Coadministration of Mefi P Syrup with etodolac can increase the risk or severity of bleeding, ulceration, and blood loss.

How to manage the interaction:
Although there is an interaction between Mefi P Syrup and etodolac, it can be taken if a doctor has advised it. However, if you experience bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact the doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidWarfarin
Severe
How does the drug interact with Mefi P Syrup:
Coadministration of Mefi P Syrup with warfarin can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Mefi P Syrup and warfarin, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Paracetamol + Mefenamic acidEverolimus
Severe
How does the drug interact with Mefi P Syrup:
Coadministration of Mefi P Syrup with everolimus can increase the risk or severity of kidney problems

How to manage the interaction:
Although there is an interaction between Mefi P Syrup and everolimus, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, less desire to eat, sudden weight gain or weight loss, shortness of breath, muscle cramps, tiredness, weakness, or dizziness, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidEnoxaparin
Severe
How does the drug interact with Mefi P Syrup:
Taking Mefi P Syrup with enoxaparin can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Mefi P Syrup and enoxaparin, they can be taken together if prescribed by a doctor. However, if you experience bruising, swelling, vomiting, headache, dizziness, weakness, or blood in urine or stool, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidLithium
Severe
How does the drug interact with Mefi P Syrup:
Co-administration of lithium with Mefi P Syrup can increase blood levels of lithium.

How to manage the interaction:
Although there is an interaction between Mefi P Syrup and lithium, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, confusion, diarrhea, vomiting, or muscle weakness. Do not discontinue any medications without consulting a doctor.
Paracetamol + Mefenamic acidEdoxaban
Severe
How does the drug interact with Mefi P Syrup:
Taking edoxaban together with Mefi P Syrup may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Mefi P Syrup and edoxaban, it can be taken if your doctor has suggested it. If you experience dizziness, black or tarry stools, severe headache, weakness, or vomiting, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Paracetamol + Mefenamic acidEthanol
Severe
How does the drug interact with Mefi P Syrup:
Taking ethanol with Mefi P Syrup can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Mefi P Syrup, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, weakness, unusual bleeding or bruising, skin rash, nausea, vomiting, or yellowing of the skin or the whites of your eyes.. Do not discontinue any medications without consulting a doctor.
Paracetamol + Mefenamic acidTenofovir alafenamide
Severe
How does the drug interact with Mefi P Syrup:
Taking Mefi P Syrup with tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Mefi P Syrup and tenofovir alafenamide, it can be taken if advised by a doctor. However, if you experience nausea, vomiting, less desire to eat, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, tiredness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Paracetamol + Mefenamic acidPiroxicam
Severe
How does the drug interact with Mefi P Syrup:
Coadministration of Mefi P Syrup with piroxicam can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between Mefi P Syrup and piroxicam, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Mefi P Syrup is used for the treatment of pain, inflammation, migraine headache, period pain, muscle pain, tooth pain, joint pain, pain after surgery, ear pain, fever, flu, osteoarthritis, and rheumatoid arthritis.
Mefi P Syrup blocks the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical, prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site.
Mefi P Syrup is used to reduce and relieve pain and inflammation associated with osteoarthritis and rheumatoid arthritis. Arthritis is joint tenderness and swelling.
Avoid taking Mefi P Syrup if you have stomach ulcers, bleeding problems, or heart problems. Talk to your doctor regarding your concerns; he/she may prescribe alternative medicine.
Diarrhoea might be a side-effect of Mefi P Syrup. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Mefi P Syrup is used to relieve menstrual (period) pain and manage excessively heavy periods. Take Mefi P Syrup only as prescribed by the doctor.
Mefi P Syrup is generally prescribed for short-term use. Do not take Mefi P Syrup for longer durations, as it might increase the risk of kidney problems and stomach bleeding.
It is highly recommended to take Mefi P Syrup with food, milk, or right after a meal. Taking it on an empty stomach can increase the risk of stomach irritation, heartburn, and nausea. If you continue to experience stomach discomfort, talk to your doctor.
Mefi P Syrup is generally not recommended during pregnancy, especially from 30 weeks of pregnancy onward (the third trimester), because the mefenamic acid component can cause premature closure of the baby's ductus arteriosus and may interfere with normal labour. If you are pregnant or planning to become pregnant, talk to your doctor to find a safer pain relief alternative.
No, you should avoid drinking alcohol while taking Mefi P Syrup. Alcohol increases the risk of serious stomach bleeding and can place extra strain on your liver. For your safety, talk to your doctor or pharmacist.
If you notice a skin rash, hives, or peeling skin after taking Mefi P Syrup, stop using the medication immediately and seek medical attention. These can be signs of a serious allergic reaction. Talk to your doctor before taking any similar pain relievers.
Some blood pressure medicines may not work as well when taken with Mefi P Syrup, and the combination can sometimes affect your kidney function. Your doctor may need to monitor your blood pressure and kidney health closely. Talk to your doctor before combining these medications.
Mefi P Syrup is generally intended for short-term relief of acute pain and inflammation. Using it long-term for chronic conditions like arthritis requires careful supervision by a healthcare professional to avoid kidney, liver, or stomach complications. Talk to your doctor to see if this is the right long-term treatment for you.
The safety and dosage of Mefi P Syrup for children depend on their age and weight. You should never give this adult medication to a child without direct guidance from a paediatrician. Talk to your doctor or pharmacist.

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Country of origin

India

Manufacturer/Marketer address

Plot No.7 Hsiidc Rai 131029 Rai, Industrial Area, Sonipat, Haryana 131029
Other Info - MEFI137
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