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  3. Mefliam Tablet

Mefliam Tablet, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Mefliam Tablet is used to treat malaria. It contains Mefloquine which works by killing malaria-causing parasites. In some cases, this medicine may cause side effects such as sleeping problems, headache, dizziness, vertigo (loss of balance), itching, nausea, vomiting, stomach pain or diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

MEFLOQUINE-250MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Mefliam Tablet

Mefliam Tablet comes into the category of 'Antimalarials' mainly used to treat or prevent malaria. Malaria is a life-threatening disease that is spread by the bite of an infected mosquito (anopheles mosquito). When an infected mosquito bites a healthy person, then it transmits the infections into the bloodstream, which after several days starts affecting the red blood cells & liver cells, breaking them in the process. Usually, an infected person starts noticing the symptoms of malaria within 10 days to 4 weeks after the infection that include shaking chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhea, anemia, muscle pain, convulsions, coma and bloody stools.

Mefliam Tablet contains ‘mefloquine’, which acts by killing the malarial parasites. It works by enhancing the levels of heme in the blood. Haeme is a substance toxic to the malarial parasite. In this way, the parasite gets killed by its toxic by-products released during its metabolism of hemoglobin. This kills the parasite and prevents the infection from spreading.

Take Mefliam Tablet as prescribed by your doctor. You are advised to take Mefliam Tablet for as long as your doctor has prescribed it for you based on your medical condition. You may experience sleeping problems (bad dreams, sleepiness, unable to sleep), headache, dizziness, vertigo (loss of balance), itching, nausea, vomiting, stomach pain or diarrhoea. Most of these side effects of Mefliam Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking Mefliam Tablet, please inform your doctor if you have any allergy to Mefliam Tablet or its active part. Mefliam Tablet should not be taken in conditions like liver disease, kidney disease, eye problems and epilepsy/ fits disorder. Mefliam Tablet should not be given to children less than 3 months. If you are pregnant or breastfeeding, please inform your doctor before taking Mefliam Tablet. Do not drive or use a machine while taking Mefliam Tablet as it causes dizziness. If you have some tolerance for sugar, you should not take Mefliam Tablet. Contact your doctor before taking Mefliam Tablet.

Uses of Mefliam Tablet

Treatment of Malaria

Directions for Use

Take Mefliam Tablet preferably after a meal or as advised by your doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Mefliam Tablet falls into a group of medicines known as antimalarials, which are indicated for treating or preventing malaria. Mefliam Tablet contains mefloquine, which is quinoline medicine, that works by enhancing the levels of heme in the blood. Haeme is a substance toxic to the malarial parasite. In this way, the parasite gets killed by its toxic by-products released during its metabolism of hemoglobin. This kills the parasite and prevents the infection from spreading.

How Mefliam Tablet Works

Mefliam Tablet contains ‘mefloquine’, which acts by killing the malarial parasites. It works by enhancing the levels of heme in the blood. Haeme is a substance toxic to the malarial parasite. In this way, the parasite gets killed by its toxic by-products released during its metabolism of hemoglobin. This kills the parasite and prevents the infection from spreading.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mefliam Tablet
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
  • Concentration, stress and anxiety can be improved by meditation and deep breathing.
  • You can increase your energy, memory and capacity to avoid distractions by exercising regularly.
  • Avoiding multitasking is advised.
  • Fruits, vegetables, whole foods and oily fish help to improve your nutrition.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Mefliam Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, diarrhoea, pain on the right side of your stomach, dizziness, loss of balance, difficulty falling or staying asleep, unusual dreams, tingling in your fingers or toes, difficulty walking, seizures, and changes in mental health. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Mefliam Tablet should not be taken in conditions like epilepsy/fits, heart problems, liver/ kidney disease, eye problems, inflammation in the lungs, and low blood sugar level. Before taking Mefliam Tablet inform your doctor if you have suicidal thoughts, severe anxiety, abnormal dreams, insomnia (difficulty in sleeping), depression, feeling restless and confusion. Before taking Mefliam Tablet, please inform your doctor if you have any allergy to Mefliam Tablet or its active part Mefliam Tablet should not be given to children less than 3 months. If you are pregnant or breastfeeding, please inform your doctor before taking Mefliam Tablet. Do not drive or use a machine while taking Mefliam Tablet as it causes dizziness. If you have some tolerance for sugar, you should not take Mefliam Tablet. Contact your doctor before taking Mefliam Tablet.

Drug-Drug Interactions

verifiedApollotooltip
MefloquineZiprasidone
Critical
MefloquineOxytocin
Severe

Drug-Drug Interactions

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MefloquineZiprasidone
Critical
How does the drug interact with Mefliam Tablet:
Taking Mefliam Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Mefliam Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
MefloquineOxytocin
Severe
How does the drug interact with Mefliam Tablet:
Taking oxytocin with Mefliam Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Oxytocin with Mefliam Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience if you develop sudden dizziness, lightheadedness, fainting, shortness of breath contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MefloquineCeritinib
Severe
How does the drug interact with Mefliam Tablet:
Taking ceritinib together with Mefliam Tablet can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Taking Ceritinib with Mefliam Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
MefloquineKetoconazole
Severe
How does the drug interact with Mefliam Tablet:
Coadministration of Mefliam Tablet and ketoconazole can increase the blood levels and can result in a possibly harmful heart rhythm irregularity.

How to manage the interaction:
Although taking Ketoconazole and Mefliam Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, you should consult a doctor immediately. Ketoconazole should not be taken with Mefliam Tablet or within 15 weeks of your last dose of Mefliam Tablet. Do not stop using any medications without a doctor's advice.
MefloquineOlanzapine
Severe
How does the drug interact with Mefliam Tablet:
The combined use of Mefliam Tablet and Olanzapine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Mefliam Tablet and Olanzapine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MefloquineMoxifloxacin
Severe
How does the drug interact with Mefliam Tablet:
Using Moxifloxacin together with Mefliam Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Moxifloxacin and Mefliam Tablet, but it can be taken if prescribed by a doctor. If you experience irregular heart rhythm, dizziness, or difficulty breathing, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
MefloquineGalantamine
Severe
How does the drug interact with Mefliam Tablet:
Combining Mefliam Tablet with Galantamine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Galantamine with Mefliam Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms like a very slow heart rate, low blood pressure, dizziness, fainting, or an irregular heartbeat, call your doctor right away. Do not stop using any medications without talking to a doctor.
MefloquineGatifloxacin
Severe
How does the drug interact with Mefliam Tablet:
Taking Gatifloxacin with Mefliam Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Mefliam Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MefloquineDisopyramide
Severe
How does the drug interact with Mefliam Tablet:
The combined use of Mefliam Tablet and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Mefliam Tablet and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MefloquineMifepristone
Severe
How does the drug interact with Mefliam Tablet:
Co-administration of Mefliam Tablet with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Mefliam Tablet with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, weakness, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should take nutritious food as when a person has a malarial fever, their body's requirement gets increased, and also taking high carbohydrate diet, Fresh fruits and vegetables help in recovering the body fast.
  • During fever, a person may experience appetite loss, thus eating food becomes a challenge. To deal with this, one should drink glucose water, fresh fruit juices, coconut water, to supplying the body's requirements through liquids.
  • High malaria fever makes the body weak and reduces appetite to take food that helps to synthesize immune bodies and help the body deal with parasites.
  • A person should not take very high-fiber foods like green leafy vegetables, and fruits with thick skin, as the body is already in the healing stage and it also has to digest these complex foods.
  • Take proper rest, which helps the body to relax and heal faster.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Mefliam Tablet Substitute

Substitutes safety advice

  • Meflotas 250 mg Tablet 2's

    by Others

    ₹52.45per tablet

  • Altimef Tablet

    by Others

    ₹50.70per tablet

  • Confal 250mg Tablet

    by Others

    ₹39.43per tablet

  • Larimef 250 mg Tablet 4's

    by Others

    ₹75.15per tablet

  • MEFLOC 250MG TABLET

    by Others

    ₹47.90per tablet

Product Substitutes

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Alcohol

Unsafe

A person should limit the consumption of alcohol as it may worsen the side effects. It may lead to liver damage.

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Pregnancy

Caution

Mefliam Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is not safe to breastfeed while taking Mefliam Tablet. A patient is advised to take this drug only at a doctor's consultation.

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Driving

Caution

Mefliam Tablet may cause dizziness, so one should avoid driving or doing any activity that needs mental alertness.

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Liver

Caution

Mefliam Tablet should be used with caution in patients with impaired liver function. Consult your doctor before using Mefliam Tablet.

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Kidney

Caution

Mefliam Tablet should be used with caution in patients with impaired kidney function. Consult your doctor before using Mefliam Tablet.

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Children

Caution

Mefliam Tablet should not be used for children below 3 months. Mefliam Tablet should be used only when prescribed by a child specialist.

FAQs

Mefliam Tablet is used to treat malaria.

Mefliam Tablet is safe if used in the dose and duration recommended by your doctor. Take it just as instructed and do not skip any dose. Follow your doctor's directions carefully and inform your doctor if any of the side effects disturb you.

No, do not stop taking Mefliam Tablet without asking your doctor even if you are feeling better. Your symptoms may enhance before the infection is completely cured. Thus, for better and complete treatment, it is instructed to continue your treatment for the recommended duration.

It has been reported that taking Mefliam Tablet for a long time may cause irreversible damage to the retina of your eye which can even lead to vision loss, so take this medicine for the time suggested by the doctor.

High fever with chills is the main symptom of malaria. The symptoms include feeling of cold and shivering, high fever, sweating. It also includes headache, nausea, body pain and weakness.

No, do not take antifungal (ketoconazole) with Mefliam Tablet and for at least 15 weeks after you stop taking it. Serious, life-threatening side effects on your heart can occur. Consult your doctor for further advice.

Country of origin

India

Manufacturer/Marketer address

No.248/13, 2nd Floor, 67Th Cross, 5Th Block, Rajajinagar, Bangalore - 560010
Other Info - ME18834

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Author Details

Doctor imageDoctor badge

Written By

Veda Maddala

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.9670.pdf
  2. https://www.drugs.com/cdi/mefloquine.html
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