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compositionComposition:CITICOLINE-250MG
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Megacholin Rf 250 mg Injection 2 ml belongs to the group of psychostimulant class of medicines. It is used in the treatment of Disturbances of consciousness resulting from brain operation, head injuries, and acute stage of cerebral infarction (stroke) in adults. This medication works by preventing the release of free fatty acids and raising the synthesis of phosphatidylcholine and sphingomyelin, which stabilizes the cell membranes. Side effects of this medicine include insomnia (difficulty sleeping), nausea, feeling of warmth, loss of appetite, convulsions, and injection site reactions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

CITICOLINE-250MG

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Megacholin Rf 250 mg Injection 2 ml

Megacholin Rf 250 mg Injection 2 ml is a prescription injection primarily used to support brain recovery following a stroke, physical head trauma, or during cognitive decline. This parenteral medicine helps protect nerve cells from damage and aids in restoring lost brain functions. It plays a critical role in standard medical care to help patients regain cognitive and motor abilities.

This medicine is injected directly into a vein or muscle by a qualified healthcare professional, ensuring consistent delivery into the body. Because it is given as an injection, food intake does not affect how it works. Combining this treatment with a brain-healthy diet and structured physical therapy can significantly improve your recovery outcomes.

While receiving this medicine, some patients may experience mild side effects such as headaches, dizziness, or temporary changes in blood pressure. These symptoms are usually mild and temporary, but you must consult your doctor immediately if you experience severe allergic reactions, breathing difficulties, or chest tightness.

Do not take this if you have a known severe allergy to this medication or if you suffer from severe high muscle tone (hypertonia) of the nervous system. Before starting this treatment, talk to your doctor if you have a history of bleeding disorders, kidney disease, or severe brain swelling.

This injection can interact with certain medications, especially those used for Parkinson's disease, so keep your doctor fully informed of all drugs you take. Avoid alcohol and smoking during treatment as they can impair nerve recovery and increase dizziness. If you are pregnant, breastfeeding, or an elderly patient, consult your healthcare provider to ensure this treatment is safe for you.

Uses of Megacholin Rf 250 mg Injection 2 ml

Megacholin Rf 250 mg Injection 2 ml helps support brain cell repair and improves brain function after injury or reduced blood flow. Your doctor may recommend it for the following conditions:

  • Acute stroke recovery: Megacholin Rf 250 mg Injection 2 ml helps repair damaged nerve cell membranes and improves blood flow to the brain, which supports the recovery of speech, movement, and daily functioning after a stroke.
  • Head trauma and brain injuries: Megacholin Rf 250 mg Injection 2 ml aids in reducing brain swelling and promotes the healing of brain tissue after physical accidents, helping to restore normal neurological activity.
  • Cognitive decline and memory disorders: Megacholin Rf 250 mg Injection 2 ml supports overall brain cell health in chronic brain vascular diseases, helping to manage age-related memory loss and decline in mental alertness.

Key Benefits

Megacholin Rf 250 mg Injection 2 ml helps support brain recovery and improve cognitive function after brain injury or reduced blood flow. Key benefits include:

  • Supports recovery after stroke or head injury: Helps protect brain cells and supports the recovery of speech, movement, coordination, and daily functioning during rehabilitation.
  • Protects brain cells: Helps reduce further damage to brain cells and supports their repair and healthy function.
  • Improves memory and mental function: May enhance memory, concentration, mental alertness, and overall cognitive performance.
  • Reduces mental fatigue: Helps improve focus and supports participation in daily activities and rehabilitation programmes.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Megacholin Rf 250 mg Injection 2 ml will be administered by the doctor.
  • Do not self-administer.

How Megacholin Rf 250 mg Injection 2 ml Works

Megacholin Rf 250 mg Injection 2 ml contains citicoline, which helps protect and repair brain cells. It supports the production of phospholipids, essential building blocks of the protective outer membrane of nerve cells. After a stroke or head injury, these membranes can become damaged. Megacholin Rf 250 mg Injection 2 ml helps rebuild them, reducing further cell damage and supporting the brain's natural healing process. Megacholin Rf 250 mg Injection 2 ml also increases the levels of acetylcholine, a chemical messenger involved in memory, learning, and muscle control. By improving communication between nerve cells and supporting healthy blood flow and oxygen supply to the brain, it helps improve cognitive function and supports recovery of lost brain functions.
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Alcohol

Caution

Avoiding alcohol is recommended to rule out any possibility of side effects.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

There are no adequate and well-controlled studies on nursing mothers. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Megacholin Rf 250 mg Injection 2 ml may cause irregular body movement and double vision; thus, avoid using machinery or driving.

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Liver

Caution

Let your doctor know if you have a history of liver impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Let your doctor know if you have had a history of kidney impairment/disorder. In aged patients with impaired renal function, the dose should be adjusted.

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Children

Caution

Limited information is available. Please consult your doctor.

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Heart

Caution

Megacholin Rf 250 mg Injection 2 ml is generally safe for individuals with heart problems, but caution is advised. It may cause side effects like irregular heart rate or changes in blood pressure, so medical supervision is essential.

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Geriatrics

Caution

Megacholin Rf 250 mg Injection 2 ml can be used in geriatric patients, often to support cognitive function or recovery from stroke. However, older adults may require careful monitoring for blood pressure changes or other mild side effects.

What if I have taken an overdose of Megacholin Rf 250 mg Injection 2 ml

Because this medication is injected under medical supervision, an overdose is highly unlikely. If you suspect you have received too much of this medicine or if you experience unusual symptoms after an injection, seek immediate medical attention or inform your care team right away.

Diet & Lifestyle Advise

  • Eat a brain-healthy diet: Focus on foods rich in omega-3 fatty acids (such as walnuts, flaxseeds, and fish), antioxidants (like berries and leafy greens), and whole grains to support nerve cell recovery.
  • Stay physically active: Engage in regular physical therapy or light daily exercises as recommended by your doctor to help rebuild muscle memory and coordination.
  • Engage in cognitive exercises: Challenge your brain with activities like reading, puzzles, memory games, or conversational exercises to stimulate neural pathways.
  • Stay hydrated: Drink plenty of water throughout the day, as proper hydration is vital for maintaining healthy brain function and circulation.
  • Prioritize rest: Ensure you get adequate, high-quality sleep every night, as the brain repairs and reorganizes itself during rest.
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How Soon It Starts Working

The time required for Megacholin Rf 250 mg Injection 2 ml to start to work: The onset time of Megacholin Rf 250 mg Injection 2 ml has not been clinically established. The time for which the effects of Megacholin Rf 250 mg Injection 2 ml last: The duration of Megacholin Rf 250 mg Injection 2 ml’s effect is clinically not established.

What if you forget to take Megacholin Rf 250 mg Injection 2 ml

Since this medicine is injected by a healthcare professional in a clinic or hospital, it is unlikely that you will miss a dose. However, if you miss an appointment for your injection, contact your doctor or healthcare provider immediately to reschedule. Do not try to double the dose to make up for a missed one.

Storage

• Store Megacholin Rf 250 mg Injection 2 ml at 20°C to 25°C in its original packaging, protected from direct sunlight and moisture. Do not freeze the injection.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inspect the solution: Before injection, always check the liquid in the vial. It should be clear and colourless. Do not use the medicine if you notice any cloudiness, discolouration, or floating particles.
  • Check for damage: Ensure the glass vial or ampoule is not cracked, chipped, or leaking before use.
  • Never reuse equipment: If administering at home under medical supervision, always use a fresh, sterile needle and syringe for every injection, and dispose of them immediately in a puncture-proof sharps container.
  • Rotate injection sites: If you are receiving intramuscular injections, rotate the injection site each time to prevent soreness, swelling, or tissue damage.
  • Monitor blood pressure: Keep a regular track of your blood pressure, as this medicine can cause temporary changes in blood pressure levels.

Drug-Drug Interactions

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  • Levodopa (L-Dopa): Combined use may increase the effects of levodopa, which is used for Parkinson's disease. Your doctor may need to adjust your levodopa dose.
  • Meclofenoxate: Do not take Megacholin Rf 250 mg Injection 2 ml together with medications containing meclofenoxate, as they may interfere with each other's effects on the brain.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Megacholin Rf 250 mg Injection 2 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[PSYCHOSTIMULANTS]

FAQs

Megacholin Rf 250 mg Injection 2 ml injection is primarily used to support brain recovery and improve memory, movement, and cognitive functions in patients recovering from a stroke, head injury, or age-related mental decline. Talk to your doctor to see if this treatment is right for you.
This medicine is injected either directly into a muscle (intramuscular) or slowly into a vein (intravenous infusion) by a trained healthcare professional. Talk to your doctor if you have questions about your administration schedule.
This medicine can sometimes cause dizziness or mild changes in blood pressure. It is best to avoid driving or operating heavy machinery immediately after your injection until you know how the medication affects you. Talk to your doctor for personalised advice.
There is limited safety data regarding the use of this medicine in pregnant women. It should only be used during pregnancy if the potential benefits outweigh the risks. Talk to your doctor before receiving this treatment if you are pregnant or planning to become pregnant.
You should avoid alcohol and smoking during your treatment, as they can interfere with brain recovery and increase side effects like dizziness. Talk to your doctor or pharmacist about other substances you should avoid.
While rare, serious side effects can include severe allergic reactions (like swelling of the face or throat and breathing difficulties) or irregular heartbeats. If you experience any of these symptoms, seek emergency medical care immediately and talk to your doctor.
This medicine can interact with levodopa, a common treatment for Parkinson's disease, by increasing its effects. Your doctor may need to adjust your medication doses if you use them together. Talk to your doctor to ensure safe use.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - MEG0483
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