apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Megatas-S 50 Tablet 10's

Prescription drug
Trailing icon
Megatas-S 50 Tablet 10's, Pack of 10
Megatas-S 50 Tablet 10's, Pack of 10
Megatas-S 50 Tablet 10's, Pack of 10
coupon
coupon
coupon
Extra 15% Off with Bank Offers

Composition :

MIRABEGRON-50MG + SOLIFENACIN-5MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Megatas-S 50 Tablet

Megatas-S 50 Tablet is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and dysuria (painful or difficult urination).

Megatas-S 50 Tablet contains Solifenacin and Mirabegron. Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. Mirabegron relaxes the muscles of the bladder; this prevents symptoms of an overactive bladder.

Megatas-S 50 Tablet may cause side effects such as dry mouth, constipation, headache, high blood pressure, and vomiting. Most of these side effects do not require medical attention and resolve over time. However, talk to your doctor if any side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Megatas-S 50 Tablet is not recommended for children. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Megatas-S 50 Tablet

Megatas-S 50 Tablet is used in the treatment of Overactive bladder. The detailed uses of Megatas-S 50 Tablet are as follows:

  • Treating overactive bladder (OAB): Megatas-S 50 Tablet helps manage symptoms like urinary urgency, frequency, and urge incontinence by relaxing bladder muscles and reducing involuntary contractions.
  • Enhancing bladder control and urine-holding capacity: Megatas-S 50 Tablet combines Mirabegron, which relaxes bladder muscles to increase storage volume, and Solifenacin, which prevents spasms by blocking muscarinic receptors, together improving continence and reducing urgency.
  • Reducing nighttime urination and leakage: Megatas-S 50 Tablet is effective in lowering episodes of nocturia and accidental urine leakage, improving sleep and quality of life.

Have a query?

Directions for Use

  • Megatas-S 50 Tablet can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Megatas-S 50 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Megatas-S 50 Tablet is a combination of Solifenacin and Mirabegron, used to effectively manage symptoms of an overactive bladder (OAB).
  • It treats symptoms such as urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and painful or difficult urination (dysuria).
  • Solifenacin is an anticholinergic agent which reduces involuntary bladder contractions and increases bladder capacity.
  • It allows the bladder to hold more urine and helps reduce the sudden urge to urinate.
  • Mirabegron is a beta-3 adrenergic agonist which relaxes bladder muscles for improved control. It prevents frequent, urgent, or uncontrolled urination.
  • Megatas-S 50 Tablet improves bladder control and urinary flow, reduces episodes of urine leakage and enhances overall comfort and quality of life in individuals with overactive bladder.

How Megatas-S 50 Tablet Works

Megatas-S 50 Tablet contains Solifenacin (anti-cholinergic) and Mirabegron (beta-3 adrenergic agonist). Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Megatas-S 50 Tablet helps in treating an overactive bladder.

Storage

• Store in a cool and dry place away from sunlight.• Keep Megatas-S 50 Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Megatas-S 50 Tablet
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Megatas-S 50 Tablet

Avoid exceeding the recommended dose as it may cause unpleasant side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Megatas-S 50 Tablet if you are allergic to any of its contents.
  • Inform your doctor if you have glaucoma, myasthenia gravis, ulcerative colitis, urinary retention, high blood pressure, angioedema, kidney or liver problems.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Megatas-S 50 Tablet is not recommended for children.
  • Megatas-S 50 Tablet may cause blurred vision, so drive with caution.
  • Avoid or limit alcohol consumption with Megatas-S 50 Tablet as it could lead to increased dizziness.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

verifiedApollotooltip
MirabegronEliglustat
Critical
SolifenacinItraconazole
Critical

Drug-Drug Interactions

Login/Sign Up

MirabegronEliglustat
Critical
How does the drug interact with Megatas-S 50 Tablet:
Coadministration of Eliglustat and Megatas-S 50 Tablet can significantly increase the blood levels of eliglustat. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Megatas-S 50 Tablet with Eliglustat is not recommended, it should be taken only when advised by a doctor. You should seek immediate medical help if you develop symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, irregular heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without a doctor's advice.
SolifenacinItraconazole
Critical
How does the drug interact with Megatas-S 50 Tablet:
The blood levels and effects of Megatas-S 50 Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Megatas-S 50 Tablet and Itraconazole may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
SolifenacinPotassium chloride
Critical
How does the drug interact with Megatas-S 50 Tablet:
Taking Megatas-S 50 Tablet and Potassium chloride together can increase the risk of stomach ulcers, bleeding, and stomach injury.

How to manage the interaction:
Taking Megatas-S 50 Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
SolifenacinMesoridazine
Critical
How does the drug interact with Megatas-S 50 Tablet:
Using Mesoridazine together with Megatas-S 50 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Megatas-S 50 Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor.
MirabegronBrexpiprazole
Severe
How does the drug interact with Megatas-S 50 Tablet:
A combined use of Megatas-S 50 Tablet and Brexpiprazole may increase the level of Brexpiprazole in blood. This can increase the risk or severity of side effects.

How to manage the interaction:
There could be a possible interaction between Megatas-S 50 Tablet and Brexpipraole, it can be taken together if your doctor has advised them. However, if you experience drowsiness, fatigue, seizure, chest pain or tightness, irregular heart rates, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronThioridazine
Severe
How does the drug interact with Megatas-S 50 Tablet:
Combine use of Megatas-S 50 Tablet and thioridazine may raise the blood levels of thioridazine. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Megatas-S 50 Tablet and thioridazine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience stomach pain, diarrhea, dehydration, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronTamoxifen
Severe
How does the drug interact with Megatas-S 50 Tablet:
Coadministration of Megatas-S 50 Tablet and Tamoxifen may reduce the effects of tamoxifen.

How to manage the interaction:
Taking Megatas-S 50 Tablet and Tamoxifen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience painful urination, constipation, dry mouth, headache, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MirabegronAripiprazole
Severe
How does the drug interact with Megatas-S 50 Tablet:
Combining Aripiprazole with Megatas-S 50 Tablet can increase the levels of Aripiprazole in the body. This can lead to increased risk or severity of side effects.

How to manage the interaction:
Although taking Megatas-S 50 Tablet and Aripiprazole together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs like feeling sleepy, having seizures, unusual muscle movements, low blood pressure, feeling confused, muscle spasms, twitching in your jaw, shaking or jerking in your arms and legs, feeling nervous or restless, dizziness, lightheaded, or fainting contact the doctor right away. Do not stop using any medications without a doctor's advice.
MirabegronPimozide
Severe
How does the drug interact with Megatas-S 50 Tablet:
Combined use of Megatas-S 50 Tablet and Pimozide may increase the level of pimozide in the blood. This can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Megatas-S 50 Tablet and Pimozide may lead to an interaction but they can be taken together if your doctor has prescribed them. However, if you experience drowsiness, blurred vision, dry mouth, constipation, low blood pressure, tremors, trembling of hands, arms, legs, jaw and face, balance and Speech difficulty, or abnormal muscle movements consult a doctor. Do not discontinue any medications without consulting a doctor.
MirabegronVenetoclax
Severe
How does the drug interact with Megatas-S 50 Tablet:
Coadministration of Megatas-S 50 Tablet and Venetoclax may significantly increase the blood levels and effects of Venetoclax. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possible interaction between Megatas-S 50 Tablet and Venetoclax, but they can be taken together if your doctor has prescribed them. However, if you experience nausea, vomiting, diarrhea, fatigue, fever, chills, bleeding problems, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Pelvic floor exercises would be helpful in treating bladder spasms.
  • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, and chocolate. 
  • Avoid drinking excess alcohol or caffeinated drinks, as they can worsen the symptoms.
  • Maintain a healthy weight and exercise regularly.
  • Quit smoking.
  • Take 6-8 glasses of liquids every day.
  • Avoid processed foods. Instead, choose whole, unprocessed foods.
  • Include fruits, vegetables, and fibre-rich food in your diet.

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS

Megatas-S 50 Tablet Substitute

Substitutes safety advice
bannner image

Alcohol

Caution

You are recommended to avoid or limit alcohol consumption while taking Megatas-S 50 Tablet , as it may cause increased dizziness.

bannner image

Pregnancy

Consult your doctor

Limited information is available regarding the usage of Megatas-S 50 Tablet during pregnancy. Consult your doctor before taking Megatas-S 50 Tablet if you are pregnant.

bannner image

Breast Feeding

Consult your doctor

Limited information is available regarding the usage of Megatas-S 50 Tablet during breastfeeding. Consult your doctor before taking Megatas-S 50 Tablet if you are breastfeeding.

bannner image

Driving

Caution

Megatas-S 50 Tablet may cause blurred vision and tiredness. Drive or operate machinery only if you are alert.

bannner image

Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Megatas-S 50 Tablet is not recommended for children as safety and effectiveness have not been established.

FAQs

Megatas-S 50 Tablet is used to treat symptoms of overactive bladder (OAB) such as urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and dysuria (painful or difficult urination).

Megatas-S 50 Tablet contains Solifenacin and Mirabegron. Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Megatas-S 50 Tablet helps in treating an overactive bladder.

There is some overlap between the symptoms of both OAB and BPH. OAB occurs due to uncontrolled urinary bladder muscle contractions. The main symptom of OAB is a sudden urge to urinate that is hard to control, which is stressful. On the other hand, BPH occurs due to an enlarged prostate gland, which puts pressure on the urinary bladder, thereby causing pain during urination.

Dry mouth could be a side effect of Megatas-S 50 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Megatas-S 50 Tablet might cause hypertension. Therefore, consult your doctor before taking Megatas-S 50 Tablet if you have high blood pressure.

Constipation could be a side-effect of Megatas-S 50 Tablet . Eat fibre-rich food and drink plenty of fluids if you experience constipation. Talk to your doctor if you have severe constipation.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - MEG0530

Customers Also Bought

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 8, 2025 | 7:47 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/202611s011lbl.pdf
  2. https://www.nhs.uk/medicines/solifenacin/
  3. https://pubmed.ncbi.nlm.nih.gov/24612659/
  4. https://www.medscape.com/viewarticle/896394

Buy best Genito Urinary products by

whatsapp Floating Button
Buy Now
Add to Cart