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compositionComposition:CLINDAMYCIN-300MG
prescription
Prescription Medicine
info
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Megclid 300Mg Capsule is an antibiotic medicine used in the treatment of bacterial infections. This medicine contains clindamycin, which works by inhibiting protein synthesis in bacterial cells and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections. Common side effects include stomach pain, nausea, vomiting, diarrhoea, heartburn, and skin rash.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

CLINDAMYCIN-300MG

Manufacturer/Marketer :

Megma Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Megclid 300Mg Capsule

Megclid 300Mg Capsule is used to treat bacterial infections. Bacterial infections occur when harmful bacteria grow in the body and cause illness. They can infect any part of the body and multiply very quickly. Megclid 300Mg Capsule will not work for viral infections, such as the common cold and flu.

Megclid 300Mg Capsule contains 'Clindamycin', which works by preventing bacterial protein synthesis, inhibiting bacterial growth. It also has a bacteriostatic effect that stops bacterial reproduction.

Common side effects of Megclid 300Mg Capsule include stomach pain, nausea, vomiting, diarrhoea, heartburn, skin rash, and vaginal itching or discharge. Most of these side effects do not require medical attention and typically resolve on their own over time. If these side effects persist longer, please consult your doctor.

Inform the doctor if you are allergic to any of the components in Megclid 300Mg Capsule. Let your doctor know if you have any liver disease, kidney disease, gastrointestinal disorders, a yellow food dye allergy, or any other allergic conditions. Megclid 300Mg Capsule should be used only with a doctor's advice during pregnancy and breastfeeding.

Uses of Megclid 300Mg Capsule

Megclid 300Mg Capsule used in the treatment of bacterial infections. The detailed uses of Megclid 300Mg Capsule are as follows:

  • Treating bacterial infections: Megclid 300Mg Capsule is used to treat various bacterial infections, including those affecting the skin, respiratory tract, and female reproductive organs.
  • Bone and Joint infections: Megclid 300Mg Capsule treats bone and joint infections, such as osteomyelitis and septic arthritis, caused by susceptible bacteria.
  • Intra-abdominal infections: Megclid 300Mg Capsule treats intra-abdominal infections by targeting and eliminating susceptible bacteria that cause the infection in the abdominal cavity, such as peritonitis or abscesses, helping to control the infection and promote recovery.
  • Gynecological infections: Megclid 300Mg Capsule treats gynecological infections, such as pelvic inflammatory disease (PID), bacterial vaginosis, and endometritis, by targeting susceptible bacteria that cause these infections.
  • Skin infections: Megclid 300Mg Capsule treats skin and skin structure infections, such as acne vulgaris, by targeting susceptible bacteria.
  • Dental infections: Megclid 300Mg Capsule is sometimes prescribed for dental infections, including periodontal infections and abscesses, due to its effectiveness against anaerobic bacteria.
  • Prophylaxis for surgical procedures: Megclid 300Mg Capsule may be administered as a prophylactic antibiotic before certain surgical procedures to reduce the risk of postoperative infections.

Key Benefits

  • Megclid 300Mg Capsule is an antibiotic that treats bacterial infections.
  • It works by inhibiting bacterial protein synthesis, which inhibits bacterial growth.
  • It shows a bacteriostatic effect, stopping bacterial reproduction but not killing them.
  • Megclid 300Mg Capsule effectively treats infections caused by gram-positive and anaerobic (living without air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumoniae, and Clostridium perfringens.
Side effects of Megclid 300Mg Capsule
  • Take cold water baths avoiding soap.
  • Avoid scratching and scrubbing to prevent infections while itching.
  • Use nets to prevent insects and mosquitoes.
  • Stop using lotions and creams that cause irritation.
  • Avoid alcohol and caffeine intake.
  • Abnormal liver function requires immediate medical attention. Your doctor may recommend lifestyle modifications along with needed medication.
  • Avoid intake of alcohol as it has a direct impact on liver functioning.
  • Prevent medications like paracetamol, over-the-counter painkillers or those mentioned by your doctor, as they may have issues getting metabolised in your body.
  • If you have overweight issues, losing weight can be a good thing to manage abnormal liver function.
  • Cut down the number of fatty foods that are taken daily.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Directions for Use

  • Take Megclid 300Mg Capsule with or without food as advised by your doctor.
  • It is advised to take Megclid 300Mg Capsule 3 to 4 times daily; however, follow your doctor's advice regarding the dosage and duration.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, chew, or break the medicine.

How Megclid 300Mg Capsule Works

Megclid 300Mg Capsule contains 'Clindamycin', which works by preventing bacterial protein synthesis, inhibiting bacterial growth. It also has a bacteriostatic effect that stops bacterial reproduction. Megclid 300Mg Capsule effectively treats infections caused by gram-positive and anaerobic (living without air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumoniae, and Clostridium perfringens.
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Alcohol

Caution

Avoid taking alcohol while using Megclid 300Mg Capsule since it may worsen the side effects.

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Pregnancy

Consult your doctor

Please consult your doctor before taking Megclid 300Mg Capsule if you are pregnant or planning to conceive.

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Breast Feeding

Consult your doctor

Megclid 300Mg Capsule is not recommended during breastfeeding since it can be excreted into breast milk. Please consult your doctor before taking Megclid 300Mg Capsule if you are breastfeeding.

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Driving

Safe if prescribed

Megclid 300Mg Capsule usually does not interfere with your driving ability.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before taking Megclid 300Mg Capsule since it may cause jaundice and abnormal liver function tests.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before taking Megclid 300Mg Capsule.

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Children

Consult your doctor

Megclid 300Mg Capsule should be used in children only when prescribed by a doctor. Your doctor will prescribe the dose depending on the child's age and body weight.

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Heart

Consult your doctor

Please consult your doctor before using Megclid 300Mg Capsule if you have pre-existing heart problems. Your doctor will prescribe Megclid 300Mg Capsule if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available about the use of Megclid 300Mg Capsule in geriatric patients. Please consult your physician.

What if I have taken an overdose of Megclid 300Mg Capsule

Never take more than the prescribed dose. An overdose of Megclid 300Mg Capsule may cause stomach pain, nausea, vomiting, or diarrhoea. Seek immediate medical help if you suspect that you might have taken an overdose of Megclid 300Mg Capsule.

Diet & Lifestyle Advise

  • Include whole-grain foods like multigrain bread and brown rice in your diet. 
  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. 
  • Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it can make you dehydrated and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 
health query

Have a query?

How Soon It Starts Working

  • The time required for Megclid 300Mg Capsule to start to work: Megclid 300Mg Capsule ideally shows its action within 45 minutes after administration. 
  • The time for which the effects of Megclid 300Mg Capsule last: The effect of Megclid 300Mg Capsule lasts for 6 to 8 hours.

What if you forget to take Megclid 300Mg Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not use Megclid 300Mg Capsule if you are allergic to any of its components.
  • Let your doctor know if you have any liver or kidney diseases, gastrointestinal diseases (colitis, Clostridium difficile-associated diarrhoea), yellow food dye allergy, and allergic conditions (asthma, hay fever, eczema).
  • Do not use Megclid 300Mg Capsule while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Megclid 300Mg Capsule may affect vaccine activity.
  • Pregnant and breastfeeding women should consult their doctor before taking Megclid 300Mg Capsule.
  • Megclid 300Mg Capsule should be used in children only when prescribed by a doctor.

Drug-Drug Interactions

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Drug-Drug Interaction: Megclid 300Mg Capsule may interact with antibiotics (erythromycin, rifampicin), anticoagulants (warfarin), fits medicines (phenytoin, carbamazepine), and neuromuscular blocking agents.

Drug-Food Interaction: Megclid 300Mg Capsule may interact with St. John's Wort (herbal supplement).

Drug-Disease Interaction: Before taking Megclid 300Mg Capsule, let your doctor know if you have any liver or kidney diseases, colitis, asthma, hay fever, and eczema.

ClindamycinBalsalazide
Severe
ClindamycinAtracurium
Severe

Drug-Drug Interactions

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ClindamycinBalsalazide
Severe
How does the drug interact with Megclid 300Mg Capsule:
Co-administration of Megclid 300Mg Capsule with Balsalazide may reduce the effectiveness of Balsalazide.

How to manage the interaction:
Although there is a possible interaction, Megclid 300Mg Capsule can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
ClindamycinAtracurium
Severe
How does the drug interact with Megclid 300Mg Capsule:
Co-administration of Megclid 300Mg Capsule with Atracurium can increase the risk of muscle weakness.

How to manage the interaction:
Taking Megclid 300Mg Capsule with Atracurium together can possibly result in an interaction, but it can be taken if a doctor has advised it. "Megclid 300Mg Capsule can affect the muscles and nerves in your body. When used with other medications that also affect the muscles and nerves, it can cause a serious problem called neuromuscular blockade. If you have trouble breathing or can't breathe at all, please call your doctor right away." Do not stop using any medications without a doctor's advice.
ClindamycinCapreomycin
Severe
How does the drug interact with Megclid 300Mg Capsule:
Co-administration of Capreomycin with Megclid 300Mg Capsule can increase the risk of kidney or nerve damage.

How to manage the interaction:
There may be a possibility of interaction between Megclid 300Mg Capsule and Capreomycin, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
ClindamycinItraconazole
Severe
How does the drug interact with Megclid 300Mg Capsule:
Concomitant use of Megclid 300Mg Capsule with itraconazole can reduce the metabolism and increase the levels of Megclid 300Mg Capsule in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction, Megclid 300Mg Capsule can be taken with itraconazole if prescribed by the doctor. Consult a doctor immediately if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not stop using any medications without first talking to your doctor.
ClindamycinIndinavir
Severe
How does the drug interact with Megclid 300Mg Capsule:
Concomitant use of Megclid 300Mg Capsule with indinavir may increase the effects of Megclid 300Mg Capsule.

How to manage the interaction:
Although there is a possible interaction, Megclid 300Mg Capsule can be taken with indinavir if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
ClindamycinFosphenytoin
Severe
How does the drug interact with Megclid 300Mg Capsule:
When Megclid 300Mg Capsule is taken with Fosphenytoin, it can cause the body to process Megclid 300Mg Capsule faster.

How to manage the interaction:
Although there is a possible interaction between Megclid 300Mg Capsule and Fosphenytoin, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like sudden drowsiness, fatigue, confusion, itching, burning, or tingling sensation, abnormal body movements, or loss of coordination, make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
ClindamycinKetoconazole
Severe
How does the drug interact with Megclid 300Mg Capsule:
Coadministration of use of Megclid 300Mg Capsule with ketoconazole can increase the effects of Megclid 300Mg Capsule.

How to manage the interaction:
Although there is a possible interaction, Megclid 300Mg Capsule can be taken with ketoconazole if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain or diarrhea. Do not discontinue any medication without consulting a doctor. Do not discontinue any medication without consulting a doctor.
ClindamycinAmprenavir
Severe
How does the drug interact with Megclid 300Mg Capsule:
Co-administration of Amprenavir together with Megclid 300Mg Capsule can increase the effects of Megclid 300Mg Capsule.

How to manage the interaction:
Co-administration of Megclid 300Mg Capsule with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
ClindamycinCeritinib
Severe
How does the drug interact with Megclid 300Mg Capsule:
Concomitant use of Megclid 300Mg Capsule with ceritinib can increase the effects of Megclid 300Mg Capsule

How to manage the interaction:
Although there is a possible interaction, Megclid 300Mg Capsule can be taken with ceritinib if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
ClindamycinBoceprevir
Severe
How does the drug interact with Megclid 300Mg Capsule:
Co-administration of Boceprevir together with Megclid 300Mg Capsule can increase the effects of Megclid 300Mg Capsule.

How to manage the interaction:
Although there is a possible interaction between Megclid 300Mg Capsule and Boceprevir, you can take these medicines together if prescribed by your doctor. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Megclid 300Mg Capsule is used to treat bacterial infections.
Megclid 300Mg Capsule is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.
Megclid 300Mg Capsule should be used with proper caution and doctor consultation if you have any liver or kidney disease, gastrointestinal diseases (colitis, an inflammation of the colon), yellow food dye allergy, or allergic conditions (asthma, hay fever, eczema).
Megclid 300Mg Capsule can affect live vaccines, like the typhoid vaccine, and decrease their effectiveness. Please consult a doctor before you start Megclid 300Mg Capsule if you are due to undergo any vaccinations.
Megclid 300Mg Capsule may cause abnormal liver function tests as one of its side effects. Please consult your doctor before starting Megclid 300Mg Capsule if you have any history of liver problems.
It is recommended to complete the course of Megclid 300Mg Capsule even if you feel better, as it is an antibiotic, and stopping it midway may lead to recurring infections.
Diarrhoea can be a side-effect of Megclid 300Mg Capsule. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Clindamycin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Clindamycin phosphate [Package Leaflet]. 2023. [Accessed on 20 Feb. 2024]Check here
  4. Clindamycin Phosphate Gel [Prescribing Information]. 2021. [Accessed on 21 Oct. 2024]Check here
  5. Clindamycin Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [Accessed on 31 Oct 2025]Check here
  6. Clindagel® (clindamycin phosphate) topical gel, 1%For Topical Use Only [Internet]. Dailymed.nlm.nih.gov. 2022 [Accessed on 31 Oct 2025]Check here
  7. Patrick B, Murphy, Karlyle G. Bistas, Jacqueline K.Le. Clindamycin. National Library of medicine, National center for biotechnology information. [Revised in July 2021] [Accessed on 11th May 2022]Check here

Country of origin

India

Manufacturer/Marketer address

no. 1065, street no. 1, haripur, sector - 4,, panchkula, 160022.
Other Info - MEG0400
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