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compositionComposition:METFORMIN-500MG
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Melmet-500 SR Tablet is used to treat type 2 diabetes. It contains Metformin, which helps lower blood sugar levels by reducing the amount of sugar absorbed from food and produced by the liver. It also helps the body use insulin more effectively to control blood sugar. Some people may experience side effects such as nausea, vomiting, diarrhoea, stomach pain, or loss of appetite. Before taking this medicine, inform your doctor if you are allergic to any of its ingredients, are pregnant or breastfeeding, or have any existing medical conditions. Also, tell your doctor about all the medicines you are taking.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METFORMIN-500MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Melmet-500 SR Tablet

Melmet-500 SR Tablet is a prescription medicine used to help control high blood sugar levels in people with type 2 diabetes. It works by helping the body use insulin more effectively, which helps keep blood sugar levels under control. Managing blood sugar levels can help reduce the risk of diabetes-related complications.

Take Melmet-500 SR Tablet exactly as prescribed by your doctor. It is usually taken with food to reduce the chance of stomach upset. Taking the medicine regularly, along with a healthy diet and regular exercise, helps improve blood sugar control.

Some people may experience mild side effects such as nausea, stomach discomfort, or bloating when starting treatment. These effects are usually temporary and improve as the body adjusts to the medicine. Contact your doctor immediately if you develop severe weakness, trouble breathing, or persistent muscle pain.

Before taking Melmet-500 SR Tablet , inform your doctor if you have any kidney or liver problems. This medicine is not suitable for people with severe kidney disease or severe dehydration. Your doctor may recommend blood tests to check your kidney and liver function before and during treatment.

Avoid excessive alcohol consumption while taking this medicine, as it may increase the risk of a rare but serious side effect. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, or if you are older than 65 years, so they can determine whether this medicine is right for you.

Uses of Melmet-500 SR Tablet

Melmet-500 SR Tablet is used to treat Type 2 diabetes mellitus. The detailed uses of Melmet-500 SR Tablet are as follows:

  • Type 2 Diabetes Mellitus: Melmet-500 SR Tablet helps lower baseline and post-meal blood sugar levels by improving how your body processes sugar.
  • Prediabetes: In some cases, doctors prescribe this medicine to help delay or prevent the onset of full type 2 diabetes in individuals with high-risk blood sugar levels.
  • Insulin Resistance: It helps cells become more sensitive to insulin, allowing glucose to enter cells easily instead of building up in the bloodstream.
     

Key Benefits

Melmet-500 SR Tablet provides reliable, daily support to help you manage your health and avoid the physical toll of fluctuating blood sugar levels. By keeping your blood sugar stable, this medicine brings several key health benefits:

  • Reduced Fatigue associated with high blood sugar: By helping your body convert sugar from food into usable energy more efficiently, it helps reduce the sluggishness and constant tiredness often caused by high blood sugar.
  • Protection Against Long-Term Complications: Consistent use protects your vital organs, lowering your risk of future complications such as kidney damage, vision loss, nerve pain, and cardiovascular concerns.
  • Weight-Neutral Support: Unlike many other blood sugar medications that can cause unwanted weight gain, this medicine helps maintain a stable weight and may support modest weight reduction in some individuals. However, weight-loss effects are generally modest and can vary considerably from person to person.
Side effects of Melmet-500 SR Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

To get the full benefit of Melmet-500 SR Tablet and minimise side effects, follow these simple guidelines:

  • Take the tablet orally, usually with your morning or evening meal, depending on your doctor's instructions. Taking it with food significantly reduces stomach upset.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can interfere with the medicine’s release into your body.
  • Try to take your dose at the same time every day to establish a consistent routine and keep a steady level of the medicine in your bloodstream.
  • Always follow your doctor's exact instructions regarding how many tablets to take and when to take them. Never adjust your dose without speaking to your doctor first.

How Melmet-500 SR Tablet Works

Melmet-500 SR Tablet contains Metformin, which works by reducing the amount of glucose absorbed from food and the amount produced by the liver. It also increases the body's response to insulin, a hormone that regulates blood glucose levels. Thereby, Melmet-500 SR Tablet helps control the amount of glucose (sugar) in the blood.
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Alcohol

Unsafe

It is advisable not to consume alcohol along with Melmet-500 SR Tablet to avoid unpleasant side effects like lactic acidosis.

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Pregnancy

Caution

Consult the doctor if you are pregnant. This medicine should be used during pregnancy only if clearly needed.

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Breast Feeding

Caution

Melmet-500 SR Tablet is not recommended if you are breastfeeding or if you are planning to breastfeed your baby.

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Driving

Safe if prescribed

Melmet-500 SR Tablet may not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Melmet-500 SR Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Melmet-500 SR Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor depending on your renal function. Melmet-500 SR Tablet is not recommended in severe kidney disease. Regular monitoring of kidney function tests is therefore important if you're taking Melmet-500 SR Tablet .

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Children

Caution

Melmet-500 SR Tablet is not recommended for children below 10 years of age. For children above 10 years, the dose will be recommended by the doctor.

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Heart

Consult your doctor

Please consult your doctor before using Melmet-500 SR Tablet if you have pre-existing heart problems. Your doctor will prescribe Melmet-500 SR Tablet if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Melmet-500 SR Tablet to geriatric patients. Your doctor will prescribe Melmet-500 SR Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Melmet-500 SR Tablet

Do not take more than the prescribed dose of Melmet-500 SR Tablet as it may cause overdose leading to lactic acidosis (too much lactic acid in the body). The symptoms include stomach pain with muscle cramps, vomiting, low body temperature, difficulty breathing, and a general feeling of not being well, with severe tiredness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately, as lactic acidosis may lead to coma.

Diet & Lifestyle Advise

  • Invest at least 150 minutes of your week in moderate-intensity physical activity, or 1 hour and 15 minutes of high-intensity exercise.
  • Losing weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrate-containing foods with whole-grain foods, and increase intake of fruits, veggies, and other fibre-rich foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Avoid excessive stress, as it may elevate your blood sugar levels. You can adopt stress management techniques like mindfulness, meditation, or yoga to help control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, cheese, etc.).
  • Keep your blood pressure as close to normal (140/90) as possible, as this reduces the risk of cardiovascular disease in patients with diabetes.
  • Try to quit smoking and reduce your intake of carbohydrate-rich foods such as potatoes, rice, mangoes, bread, and sugar.

Have a query?

How Soon It Starts Working

  • The time required for Melmet-500 SR Tablet to start to work: Melmet-500 SR Tablet ideally shows its action within 3 hours after administration.
  • The time for which the effects of Melmet-500 SR Tablet last: The effect of Melmet-500 SR Tablet lasts for 8 hours.

What if you forget to take Melmet-500 SR Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take it at the scheduled time. Do not take a double dose.

Storage

Store Melmet-500 SR Tablet at controlled room temperature, ideally between 20°C to 25°C (68°F to 77°F). Keep the tablets in their original packaging to protect them from light and moisture, and store them in a cool, dry place away from direct sunlight and excessive hea

Drug Warnings

  • Plan for Medical Scans: If you are scheduled for an X-ray, CT scan, or any imaging test that requires iodinated contrast dye, inform your doctor. Whether Melmet-500 SR Tablet needs to be temporarily stopped depends on your kidney function (eGFR) and the type of imaging procedure. Your healthcare provider will determine if any interruption is necessary and when it is safe to restart treatment.
  • Inform Your Surgeon: Always let your surgeon or dentist know you are taking this medicine before any scheduled surgical procedure, as you may need to pause it temporarily.
  • Monitor Your Kidney Function: Ensure you get your routine blood tests done as scheduled by your doctor, as your kidney health must be checked at least once a year while taking this medicine.
  • Watch for Vitamin B12 Levels: Long-term use of this medicine can sometimes lower your body's absorption of vitamin B12. Talk to your doctor about checking your levels if you experience unusual tingling in your hands or feet or extreme tiredness.
  • Limit Alcohol Intake: Avoid drinking heavy amounts of alcohol while on this medication, as alcohol significantly increases the risk of serious liver strain and lactic acid accumulation.

Drug-Drug Interactions

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Drug-Drug Interactions: 

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Water Pills (Diuretics): Taking these with Melmet-500 SR Tablet can affect your blood sugar levels and increase the risk of dehydration, requiring more frequent monitoring.
  • Corticosteroids: Medicines used to treat inflammation (like prednisone) can raise your blood sugar, which may reduce the effectiveness of your treatment.
  • Contrast Dyes: Iodinated contrast media used during imaging scans may require temporary interruption of Melmet-500 SR Tablet in certain patients, particularly those with significantly reduced kidney function (eGFR below 30 mL/min/1.73 m²), acute kidney injury, or selected high-risk procedures. Your healthcare provider will assess your kidney function and advise whether Melmet-500 SR Tablet should be paused and when it can be restarted.

 

Drug-Food Interactions

  • Alcohol: Excessive alcohol consumption can significantly increase the risk of lactic acidosis, a rare but potentially life-threatening complication associated with Melmet-500 SR Tablet . Alcohol-related low blood sugar is uncommon with Melmet-500 SR Tablet alone but may occur when Melmet-500 SR Tablet is taken together with other diabetes medicines that can cause hypoglycaemia, such as insulin or sulfonylureas.

     

Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking Melmet-500 SR Tablet , as it may worsen your condition or cause complications.

  • Severe Kidney Disease: This medicine is filtered through your kidneys. If you have severe kidney impairment, the drug can build up in your body, which can be highly dangerous.
  • Severe Liver Damage: A compromised liver cannot clear lactic acid efficiently, which raises the risk of acid build-up when taking this medicine.
  • Dehydration or Severe Infection: Conditions that cause severe fluid loss or low oxygen levels (like heart failure or severe lung disease) can make taking this medicine unsafe due to the risk of lactic acidosis.
MetforminIotroxic acid
Critical
MetforminIoversol
Critical

Drug-Drug Interactions

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MetforminIotroxic acid
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Iotroxic acid with Melmet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Melmet-500 SR Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIoversol
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Ioversol with Melmet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Melmet-500 SR Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Ioglycamic acid with Melmet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Melmet-500 SR Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIocarmic acid
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Melmet-500 SR Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Melmet-500 SR Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIoglicic acid
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Ioglicic acid with Melmet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Melmet-500 SR Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Iopydol with Melmet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Melmet-500 SR Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Melmet-500 SR Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Melmet-500 SR Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Iopromide with Melmet-500 SR Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Melmet-500 SR Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIomeprol
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Iomeprol with Melmet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Melmet-500 SR Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIobitridol
Critical
How does the drug interact with Melmet-500 SR Tablet:
Co-administration of Melmet-500 SR Tablet and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Melmet-500 SR Tablet with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

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FAQs

Melmet-500 SR Tablet is used to treat type 2 diabetes mellitus.

Melmet-500 SR Tablet lowers blood glucose levels by reducing glucose production in the liver, decreasing glucose absorption from food, and improving the body's response to insulin.

Some patients experience modest weight loss when taking Melmet-500 SR Tablet . This may be related to its effects on insulin regulation and a possible reduction in appetite, although the exact mechanism is not fully understood. The effect varies between individuals, and many people experience little or no weight change. Melmet-500 SR Tablet is not a weight-loss drug and should be combined with a healthy diet and regular exercise for overall health and diabetes management.

Yes, but consult your doctor before taking Melmet-500 SR Tablet with insulin, as the combination may increase the risk of low blood sugar.

Try to take your medicine at the scheduled time, and do not skip your doses. If you forget to take Melmet-500 SR Tablet , do not take a double dose to make up for your forgotten dose. Taking an overdose might cause your sugar level to fall rapidly. Try to take the next dose at the usual time.

Do not take excessive alcohol while taking Melmet-500 SR Tablet , as this may increase the risk of a life-threatening condition called lactic acidosis (too much lactic acid in the body), which causes symptoms like dizziness, drowsiness, muscle pain, fast, shallow breathing, etc.

Contact your doctor before having an X-ray or scan which involves the injection of contrast materials that contain iodine into your bloodstream, as it may affect your kidney function.

Yes, you may need to stop Melmet-500 SR Tablet before major surgery. Your doctor will advise when to stop and restart the medicine.

No. Melmet-500 SR Tablet is only prescribed for the treatment of type 2 diabetes, also called non-insulin-dependent diabetes. It is not indicated for type 1 diabetes.

Melmet-500 SR Tablet should be swallowed as a whole with water. Taking it with or after a meal helps prevent side effects affecting digestion.

Melmet-500 SR Tablet may not make you sleepy. Consult the doctor if you experience sleepiness, as it could be a sign of ketoacidosis.

Symptoms of lactic acidosis include abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness. Consult the doctor if you experience these symptoms.

Melmet-500 SR Tablet can be used during pregnancy only if prescribed by the doctor. Please consult the doctor if you are pregnant, planning for pregnancy or think you may be pregnant.

Melmet-500 SR Tablet may cause side effects like nausea, vomiting, diarrhoea, abdominal pain, and loss of appetite. Most of these side effects do not require medical attention and resolve gradually overtime. However, if the side effects persist or worsen, consult the doctor.

Store Melmet-500 SR Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.

It is highly recommended to take Melmet-500 SR Tablet with a meal rather than on an empty stomach. Taking it with food helps reduce common digestive side effects, such as nausea, bloating, and stomach upset. Talk to your doctor or pharmacist if you struggle with stomach discomfort.

You may begin to see improvements in your blood sugar levels within a couple of weeks of starting Melmet-500 SR Tablet , though it can take up to several weeks or months to see its full effect. Your doctor will monitor your blood sugar to ensure the medicine is working correctly. Talk to your doctor if your blood sugar remains high.

Mild diarrhoea is a common side effect when first starting Melmet-500 SR Tablet or when gradually increasing your dose. This usually improves within a few weeks as your body adjusts. If the diarrhoea is severe, watery, or does not go away, contact your healthcare provider to ensure you do not become dehydrated. Talk to your doctor or pharmacist.

When taken on its own, Melmet-500 SR Tablet rarely causes low blood sugar because it does not force your body to produce more insulin. However, if you take it alongside other diabetes medications, such as insulin or sulfonylureas, your risk of low blood sugar increases. Talk to your doctor or pharmacist about how to manage low blood sugar symptoms.

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Country of origin

India

Manufacturer/Marketer address

27, RACE COURSE ROAD, BANGALORE-560 001, INDIA
Other Info - MEL0017
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