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compositionComposition:MESALAMINE-500MG
prescription
Prescription Medicine
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Mesatis-500 Tablet 10's is used to treat ulcerative colitis and Crohn's disease. It contains Mesalamine, which works by inhibiting the production of certain chemical substances that cause pain and swelling. Thereby, it reduces inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding. In some cases, this medicine may cause side effects like diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas).

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MESALAMINE-500MG

Manufacturer/Marketer :

Tesla Labs

Consume Type :

Oral

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About Mesatis-500 Tablet 10's

Mesatis-500 Tablet 10's is a prescription tablet used to treat and manage ulcerative colitis, a condition that causes swelling and sores in the lining of the colon and rectum. It helps to calm active inflammation during flare-ups and works to keep the swelling from coming back. By targeting the gut directly, it provides relief from painful symptoms and helps your bowel tissue heal.

For the best results, you must take Mesatis-500 Tablet 10's consistently every day, even when you are feeling completely well. Your doctor may advise you to take this medicine with a meal or a glass of water, depending on the specific type of tablet you are prescribed. Making dietary adjustments, such as eating smaller portions and avoiding spicy or greasy foods, can also help support your digestive recovery alongside this treatment.

While taking this medicine, you might experience mild side effects like headaches, nausea, or light stomach discomfort. However, you must contact your doctor immediately if you experience severe abdominal cramps, fever, or a sudden increase in bloody diarrhoea. These serious symptoms require prompt medical evaluation to ensure your safety.

Do not take this if you have severe kidney or liver damage, or if you are allergic to aspirin or related pain relievers. Before you start taking this medicine, tell your doctor if you have active liver issues, kidney problems, or skin conditions like eczema. Your healthcare provider will evaluate whether this treatment is safe for your specific health profile.

This medicine can interact with certain pain relievers, like ibuprofen, which can increase your risk of kidney damage. It is also important to talk to your doctor or pharmacist if you are pregnant, planning to become pregnant, breastfeeding, or if you are an older adult, as your monitoring needs may differ.

Uses of Mesatis-500 Tablet 10's

Mesatis-500 Tablet 10's is used to treat and manage ulcerative colitis. The detailed uses of Mesatis-500 Tablet 10's are as follows:

  • Ulcerative Colitis (active flare-ups): Mesatis-500 Tablet 10's helps reduce swelling, pain, and bleeding in the colon and rectum when you are experiencing a sudden flare-up of symptoms.
  • Ulcerative Colitis (maintenance of remission): Mesatis-500 Tablet 10's prevents future flare-ups by keeping inflammation in check over the long term, helping you stay in remission.

Key Benefits

Mesatis-500 Tablet 10's helps manage chronic inflammatory bowel conditions by reducing inflammation in the digestive tract and relieving troublesome bowel symptoms. With regular use, it helps improve bowel function, promotes healing, and supports long-term digestive health.

  • Reduces Bowel Frequency: By controlling inflammation in the intestines, this medicine helps reduce the frequency of bowel movements, allowing you to regain better control over your daily routine.
  • Relieves Abdominal Pain and Rectal Bleeding: This medicine helps ease abdominal cramping, diarrhoea, and rectal bleeding, providing relief while allowing the intestinal lining to heal.
  • Promotes Healthy Bowel Function: By helping firm loose stools and reducing sudden bowel urgency, this medicine improves digestive comfort and daily quality of life.
  • Supports Long-Term Gut Healing: Regular use helps promote healing of the intestinal lining, improving nutrient absorption and supporting better long-term digestive health.

Directions for Use

  • Mesatis-500 Tablet 10's can be taken 1 hour before or 2 hours after meals.
  • It is usually taken 3-4 times a day or as prescribed by your doctor.
  • Swallow the whole Mesatis-500 Tablet 10's with a glass of water.
  • Do not crush, chew, or break it.

How Mesatis-500 Tablet 10's Works

Mesatis-500 Tablet 10's contains mesalamine, which works locally inside your digestive tract to reduce swelling and irritation. Instead of working throughout your entire body, the tablet is designed to release its active medicine directly onto the lining of your inflamed colon and rectum. It blocks the production of specific natural chemicals in your gut that trigger pain, redness, and swelling. Think of it as applying a soothing lotion to a sunburn, but on the inside of your bowel. By cooling down the inflamed tissue, it allows the lining of your gut to repair itself. This localised action helps minimise systemic side effects while focusing the treatment exactly where it is needed most.
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Alcohol

Caution

It is unknown whether it is safe to consume alcohol with Mesatis-500 Tablet 10's. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Consult your doctor

Mesatis-500 Tablet 10's should not be used in pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy.

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Breast Feeding

Consult your doctor

Mesatis-500 Tablet 10's should not be used in nursing mothers unless necessary. So, inform your doctor if you are a nursing mother.

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Driving

Safe if prescribed

Mesatis-500 Tablet 10's usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Limited information is available about using Mesatis-500 Tablet 10's in patients with liver disease. Inform your doctor before taking Mesatis-500 Tablet 10's if you have a history of liver disease

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Kidney

Caution

Inform your doctor before taking Mesatis-500 Tablet 10's if you have a history of kidney diseases/conditions. Mesatis-500 Tablet 10's should be used with extreme caution in patients with mild to moderate kidney impairment. It is recommended not to take Mesatis-500 Tablet 10's if you have severe kidney impairment.

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Children

Caution

Mesatis-500 Tablet 10's is not recommended for use in children below 6 yeras of age as the safety and efficacy for this medicine is not established. For children above 6 years, the physician will recommed it if necessary.

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Heart

Caution

Mesatis-500 Tablet 10's should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Mesatis-500 Tablet 10's.

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Geriatrics

Caution

Mesatis-500 Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform your doctor before using it.

What if I have taken an overdose of Mesatis-500 Tablet 10's

If you accidentally take too many tablets, seek immediate medical care or contact, even if you do not have any symptoms of illness.

Diet & Lifestyle Advise

  • Keep a detailed food journal to track what you eat and note any foods that seem to trigger your gut irritation, such as dairy, high-fat meals, or caffeine.
  • Drink plenty of water throughout the day to stay hydrated, especially if you are dealing with watery stools or diarrhoea.
  • During active flare-ups, choose soft, low-fibre foods that are easier on your digestive tract, and switch back to high-fibre foods only when your symptoms have settled.
  • Eat smaller meals more frequently throughout the day instead of three large meals to reduce stress on your digestive system.
     
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How Soon It Starts Working

The time required for Mesatis-500 Tablet 10's to start to work: The time required for Mesatis-500 Tablet 10's to show its action is unknown. 

The time for which the effects of Mesatis-500 Tablet 10's last: Mesatis-500 Tablet 10's effect lasts for 24 hours.

What if you forget to take Mesatis-500 Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Mesatis-500 Tablet 10's tablets at room temperature, ideally between 20°C to 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from direct sunlight and excess moisture.

Drug Warnings

  • Check your stool regularly; if you notice whole or partially intact tablets in your bowel movements, contact your doctor as the medicine may not be absorbing properly.
  • Your doctor will likely want to check your kidney health with simple blood and urine tests before and during your treatment.
  • This medicine can make your skin more sensitive to the sun, so be sure to wear high-factor sunscreen and protective clothing when outdoors.
  • Always inform any dentist or surgeon that you are taking this medication before undergoing any procedures.
     

verifiedApollotooltip
  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Taking Mesatis-500 Tablet 10's with NSAIDs, such as ibuprofen or naproxen, may increase the risk of kidney damage. Your doctor may monitor your kidney function, especially if you require prolonged treatment.
  • Immune-Modifying Medicines: Combining Mesatis-500 Tablet 10's with immune-modifying medicines, such as azathioprine, may increase the risk of serious blood disorders, including a reduction in blood cell counts. Your doctor may recommend regular blood tests to monitor your condition.

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verifiedApollotooltip
  • There are no known significant food interactions with Mesatis-500 Tablet 10's when taken as directed. Follow your doctor's instructions regarding food and fluid intake during treatment.

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Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

FAQs

Mesatis-500 Tablet 10's is used to treat Ulcerative colitis and Crohn's disease.
Mesatis-500 Tablet 10's works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (swelling) in the intestines and relieves stomach pain or bleeding symptoms.
You are not recommended to take Mesatis-500 Tablet 10's with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Mesatis-500 Tablet 10's with other medicines.
Yes, Mesatis-500 Tablet 10's may cause kidney stones in some patients. It is not necessary for everyone taking Mesatis-500 Tablet 10's to experience this side effect. However, if you notice blood in urine or pain in the sides of the stomach, please consult a doctor immediately. Drink adequate water while taking Mesatis-500 Tablet 10's to prevent kidney stones.
Mesatis-500 Tablet 10's should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Mesatis-500 Tablet 10's.
Some people may develop lactose intolerance (inability to digest lactose) when affected by Crohn's disease. Therefore, it is recommended to avoid dairy products if you have Crohn's disease as it may lead to adverse effects such as diarrhoea, stomach cramps, or stomach upset.
Yes, Mesatis-500 Tablet 10's may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools, or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Mesatis-500 Tablet 10's to prevent dehydration.
Do not discontinue Mesatis-500 Tablet 10's without consulting your doctor. Discuss with your doctor first if you have any concerns as stopping Mesatis-500 Tablet 10's might cause your symptoms to come back.
No, Mesatis-500 Tablet 10's is not habit-forming and does not cause addiction.
It is unknown if alcohol interacts with Mesatis-500 Tablet 10's. Please consult the doctor before drinking alcohol while taking Mesatis-500 Tablet 10's.
Mesatis-500 Tablet 10's might cause joint pain. Consult the doctor if you experience severe joint pain or if the condition persists.
Take Mesatis-500 Tablet 10's 1 hour before or 2 hours after meals.
Side effects of Mesatis-500 Tablet 10's include diarrhoea, stomach pain, headache, nausea, vomiting or flatulence (gas). If the side effects persist or worsen, please consult your doctor.
No, you must swallow the tablets whole. Crushing or breaking them destroys the protective coating that ensures the medicine reaches your colon safely. Talk to your doctor or pharmacist if you have trouble swallowing tablets.
There is currently no permanent cure for ulcerative colitis, but Mesatis-500 Tablet 10's is highly effective at managing the condition, reducing flare-ups, and helping you live symptom-free. Talk to your doctor about your long-term treatment plan.
If you occasionally see what looks like an empty tablet shell, this may just be the outer coating passing through. However, if you see whole, undissolved tablets regularly, the medicine may not be absorbing properly. Talk to your doctor.
You should avoid taking aspirin or other salicylates while on this medicine unless specifically directed by your healthcare provider, as they belong to a similar family of drugs and can increase side effects. Talk to your doctor.
Hair loss is a very rare side effect reported by a small number of people taking this type of medication, though it is often linked to the underlying inflammatory bowel disease itself. Talk to your doctor if you notice unusual hair thinning.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

41/12, Erandavana , Office No.4, Karve Road, Basement Pune ,Pune,Maharashtra,India,411004
Other Info - MES0180
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