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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Met XL-O 25 Tablet

Olmesartan+Metoprolol is a prescription medicine used to treat high blood pressure (hypertension). It combines two different blood pressure-lowering medicines to help protect your heart and blood vessels from long-term damage.

By keeping your blood pressure under control, this medicine helps lower the risk of serious complications such as stroke and heart attack. Its use in children and adolescents should only occur under specialist medical supervision, as dosing and safety considerations may differ from those in adults.

To get the most benefit, take Olmesartan+Metoprolol every day at the same time. You can take it with or without food, but it is best to follow the same routine each day. Healthy habits such as reducing salt intake, staying physically active, and managing stress can help improve blood pressure control and support your treatment.

While taking Olmesartan+Metoprolol, some people may experience mild side effects such as dizziness, lightheadedness, or tiredness as their body adjusts. However, if you develop severe dizziness, fainting, a very slow heart rate, or difficulty breathing, you should contact your doctor immediately. Regular check-ups with your healthcare provider are important to monitor how well the medicine is working for you.

Do not take this if you are pregnant, as it can cause serious harm to an unborn baby. You should also talk to your doctor before starting Olmesartan+Metoprolol if you have a history of asthma, severe chronic lung diseases, severe liver damage, kidney problems, or certain heart rhythm disorders like a very slow heart rate or heart block.

This medicine can interact with alcohol and certain other medicines. Alcohol may increase dizziness and cause your blood pressure to fall too low. If you are breastfeeding, an older adult, or planning to undergo surgery, speak with your doctor before taking this medicine. Both Olmesartan and Metoprolol can pass into breast milk, and alternative treatments may sometimes be preferred. Older adults may be more sensitive to side effects such as dizziness, low blood pressure, and a slow heart rate and may require closer monitoring during treatment. Do not start, stop, or change treatment without medical advice.

Uses of Met XL-O 25 Tablet

Olmesartan+Metoprolol is prescribed to help control high blood pressure and reduce the risk of complications associated with hypertension. Your doctor may recommend this medicine for the following use:

  • High Blood Pressure (Hypertension): Olmesartan+Metoprolol helps lower elevated blood pressure, reducing the workload on your heart and protecting your blood vessels, kidneys, and brain from long-term damage.

Key Benefits

When taken regularly as prescribed, Met XL-O 25 Tablet offers several important benefits for blood pressure control and cardiovascular health, including:

  • Dual-Action Blood Pressure Control: Provides comprehensive blood pressure control through the combined action of two medicines that work in different ways.

  • More Effective Than Single-Medicine Therapy: May be more effective at lowering blood pressure than treatment with a single medicine alone.
  • Blood Pressure Levels: Helps maintain blood pressure within a healthier target range.
  • Reduces Strain on the Heart and Blood Vessels: Reduces the workload on the heart and supports healthy blood vessel function.
  • Protects Vital Organs: Helps protect important organs, including the heart, brain, and kidneys, from damage caused by long-term high blood pressure.
  • Risk of Serious Complications: Lowers the risk of serious complications such as heart attack, stroke, heart failure, and hypertension-related kidney disease.

Directions for Use

For the best and safest results, always follow the exact instructions provided by your doctor. Use these general guidelines for taking your medication:

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can release the medicine too quickly into your body.
  • Take your dose at the same time every single day to establish a consistent routine and keep your blood pressure stable.
  • You can take this medicine with or without food, but choose one way and stick to it daily.

How Met XL-O 25 Tablet Works

Met XL-O 25 Tablet contains metoprolol and olmesartan, two active medicines that work together to lower blood pressure and reduce the workload on your heart. Olmesartan is an angiotensin II receptor blocker (ARB) that works by blocking the action of a natural substance in the body that causes blood vessels to tighten and narrow. This allows the blood vessels to relax and widen, making it easier for blood to flow through them and helping to lower blood pressure. Metoprolol is a beta-blocker that works by slowing down the heart rate and reducing the force with which the heart pumps blood. This decreases the workload on the heart and helps lower blood pressure. Together, these medicines help control high blood pressure, improve blood flow, and reduce the risk of complications such as heart attack, stroke, and other cardiovascular problems.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Met XL-O 25 Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

Met XL-O 25 Tablet should not be taken until prescribed. Met XL-O 25 Tablet is a Category B pregnancy drug which is considered unsafe for pregnant women. Met XL-O 25 Tablet can have some harmful effects on the baby (foetus); your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Consult your doctor

Met XL-O 25 Tablet is usually not recommended for breastfeeding mothers. Limited human data suggest that the drug does not significantly harm the baby. Consume only if the benefits outweigh the risks.

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Driving

Unsafe

It is not recommended to drive after taking Met XL-O 25 Tablet as it may occasionally cause drowsiness or fatigue.

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Liver

Caution

Met XL-O 25 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose.

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Kidney

Caution

Met XL-O 25 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may have to adjust the dose.

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Children

Unsafe

Met XL-O 25 Tablet is not recommended in children. The safety and efficacy of Met XL-O 25 Tablet in children have not yet been established.

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Heart

Caution

Met XL-O 25 Tablet is often prescribed to patients with heart problems to treat hypertension. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Caution

Met XL-O 25 Tablet should be taken with caution in geriatric patients. Please inform your doctor before using Met XL-O 25 Tablet .

What if I have taken an overdose of Met XL-O 25 Tablet

Do not take more than the prescribed dose of Met XL-O 25 Tablet as it may cause certain adverse effects. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Reduce Salt Intake: Limit your consumption of sodium (salt), as high salt intake directly raises blood pressure and can make your medicine less effective.
  • Eat a Heart-Healthy Diet: Focus on meals rich in whole grains, fruits, vegetables, and low-fat dairy, while avoiding foods high in saturated fats and cholesterol.
  • Stay Moderately Active: Engage in regular, moderate physical activities like walking, swimming, or cycling for at least 30 minutes most days of the week, after consulting your doctor.
  • Avoid Potassium Substitutes: Do not use salt substitutes containing potassium without consulting your doctor, as Olmesartan+Metoprolol can raise potassium levels in your blood.
  • Limit Alcohol and Quit Smoking: Avoid smoking and strictly limit your alcohol intake, as both can negatively affect your blood pressure and interact poorly with your medicine.

Have a query?

How Soon It Starts Working

  • The time required for Met XL-O 25 Tablet to start to work: The time required for Met XL-O 25 Tablet to show its action is unknown.
  • The time for which the effects of Met XL-O 25 Tablet last: The duration of action for Met XL-O 25 Tablet is unknown.

What if you forget to take Met XL-O 25 Tablet

If you miss a dose of Met XL-O 25 Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Olmesartan+Metoprolol tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep the medicine in its original packaging to protect it from direct light, heat, and moisture.

Drug Warnings

  • Do Not Stop Treatment Suddenly: Do not stop taking Met XL-O 25 Tablet suddenly, as doing so can cause a dangerous, rapid spike in your blood pressure or trigger severe heart complications. Talk to your doctor if you need to stop, as they will guide you on gradually increasing dose reduction.
  • Prevent Dizziness and Fainting: To prevent dizziness or fainting, rise slowly when moving from a lying down or sitting position to a standing position.
  • Use Caution with Driving and Machinery: Avoid driving, operating heavy machinery, or performing tasks that require mental alertness until you know how this medicine affects you.
  • Monitor Blood Sugar if You Have Diabetes: If you are diabetic, monitor your blood sugar closely, as this medicine can mask the warning signs of low blood sugar, such as a rapid heart rate.
  • Attend Regular Check-Ups: Attend all scheduled follow-up appointments and laboratory tests. Your doctor may periodically monitor your kidney function, potassium levels, heart rate, and blood pressure to ensure the medicine remains safe and effective. 
  • Report Persistent Digestive Symptoms: Contact your doctor if you develop persistent diarrhoea, chronic digestive symptoms, or unexplained weight loss while taking this medicine, especially if symptoms continue for weeks or months. Although rare, Olmesartan has been associated with a serious intestinal condition called sprue-like enteropathy. 
  • Inform Healthcare Providers: Inform any doctor, dentist, or surgeon that you are taking Met XL-O 25 Tablet before having any medical or dental procedures.

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Other Blood Pressure Medicines: Taking these medicines together may increase the risk of excessive blood pressure lowering, dizziness, or fainting.
  • Pain Relievers (NSAIDs): Medicines such as ibuprofen and naproxen may reduce the effectiveness of Olmesartan+Metoprolol and increase the risk of kidney problems.
  • Potassium Supplements: Potassium supplements and potassium-sparing diuretics may increase the risk of high potassium levels in the blood.
  • Diabetes Medications: This medicine may alter blood sugar responses and mask some warning signs of low blood sugar.

Drug-Food Interactions

  • Alcohol: Alcohol may increase dizziness, drowsiness, and the risk of low blood pressure.
  • Potassium-Rich Salt Substitutes: These products may increase potassium levels in the blood when used with this medicine.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Olmesartan+Metoprolol, as it may worsen your condition or cause complications.

  • Asthma and Severe Lung Diseases: This medicine may worsen breathing difficulties in susceptible individuals.
  • Heart Conditions: Patients with severe bradycardia (slow heart rate), heart block, or cardiogenic shock should not use this medicine unless specifically directed by a specialist.
  • Kidney and Liver Impairment: Reduced kidney or liver function may require closer monitoring and dose adjustments.
  • Renal Artery Stenosis: Patients with narrowing of the arteries supplying the kidneys may be at increased risk of worsening kidney function while taking this medicine.

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Met XL-O 25 Tablet is used to treat high blood pressure. It works by relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently.

Usually, Met XL-O 25 Tablet is prescribed for a long-term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.

When you are taking a beta-blocker, your healthcare provider may recommend that you limit your consumption of bananas and other high-potassium foods, such as papaya, tomato, avocado, and kale.

Your doctor may probably tell you to stop taking Met XL-O 25 Tablet as it lowers blood pressure (hypotension) when combined with general anesthesia before surgery. So, please inform your doctor before surgery if you are taking Met XL-O 25 Tablet .

There is no clear cut clinical evidences that confirms Met XL-O 25 Tablet increase an individual's body weight. However it can affect your body use energy and make you tired. If you are worried about your weight gain you can speak to the doctor.

Yes, Met XL-O 25 Tablet can cause increased blood potassium levels. It is recommended not to consume a potassium-rich diet or supplements while taking Met XL-O 25 Tablet to avoid an increase in blood potassium level.

It is unlikely that Met XL-O 25 Tablet affects fertility in men or women. There is not enough evidence to say for certain. For best advise, consult your doctor.

No, you should not stop taking this medicine even if you feel well and your blood pressure readings are normal. High blood pressure often has no symptoms, and stopping the medicine abruptly can lead to a dangerous spike in blood pressure. Talk to your doctor before making any changes.

Met XL-O 25 Tablet is a combination medication containing metoprolol and olmesartan. Metoprolol slows the heart rate and reduces the heart's workload, while olmesartan relaxes blood vessels and reduces fluid in the body. Together, they make it easier for the heart to pump blood and lower blood pressure.

Met XL-O 25 Tablet contains olmesartan (angiotensin receptor blocker) and metoprolol (beta-blocker). It is used in the treatment of hypertension (high blood pressure).

Taking Met XL-O 25 Tablet may increase the risk of falls, particularly for older adults. This is because the medication can cause dizziness and tiredness, making it harder to balance and increasing the likelihood of accidents. To prevent this, avoid getting/standing up suddenly; lie down if you feel dizzy and get up slowly only when you feel better.

Avoid drinking alcohol while taking Met XL-O 25 Tablet to prevent unpleasant side effects. Alcohol can increase the risk of dizziness, fainting, and high blood pressure.

Met XL-O 25 Tablet may cause headaches as a side effect. Try relaxing/resting, massages, and apply a cold/hot compress if you experience a headache. However, consult the doctor if the headache continues.

Met XL-O 25 Tablet may cause constipation in some people. To prevent this, eat a balanced diet rich in fiber and stay hydrated by drinking plenty of water. If you experience constipation, don't take laxatives without consulting your doctor first.

The feeling of nausea and vomiting can be reduced by eating smaller meals more frequently, avoiding spicy or fatty foods that can irritate the stomach, staying hydrated by drinking plenty of water and avoiding lying down after taking the medication.

To manage your blood pressure, aim for a healthy weight and engage in regular physical activity (at least 150 minutes/week). Follow a balanced diet rich in whole grains, fruits, veggies, and low-fat dairy products. Limit alcohol intake, quit smoking and manage stress through mindfulness and quality time with loved ones. Monitor your blood pressure daily and consult your doctor if you notice significant fluctuations.

The common side effects of Met XL-O 25 Tablet may include headaches, nausea, dizziness, increased potassium levels, and low blood pressure. Most of these side effects of Met XL-O 25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You should consult your doctor or pharmacist before taking pain relievers like ibuprofen or naproxen. These medicines can decrease the effectiveness of Olmesartan+Metoprolol and increase the risk of kidney problems. Talk to your doctor for safe pain management alternatives.

No, Olmesartan+Metoprolol should not be taken during pregnancy. It can cause serious harm, birth defects, or even death to an unborn baby. If you suspect you are pregnant or are planning a pregnancy, talk to your doctor immediately to switch to a safer alternative.

Breastfeeding while taking this medicine should only occur under medical supervision. Both Olmesartan and Metoprolol can pass into breast milk, and alternative treatments may be preferred depending on your individual situation and your baby's age and health. Do not stop breastfeeding or stop your medicine on your own. Talk to your doctor to determine the safest option for you and your baby.

Sit or lie down immediately to prevent fainting. If the dizziness is severe, frequent, or accompanied by a very slow heart rate, confusion, or difficulty breathing, contact your doctor or seek emergency medical help right away.

Yes, one of the active components can mask the symptoms of low blood sugar, such as a fast heart rate or palpitations. If you have diabetes, monitor your blood sugar levels regularly and talk to your doctor about managing your condition safely.

It is highly recommended to avoid or strictly limit alcohol while taking this medicine. Alcohol can increase the blood pressure-lowering effect of Olmesartan+Metoprolol, making you feel severely dizzy, lightheaded, or tired. Talk to your doctor about safe limits.

You should avoid salt substitutes that contain potassium, as well as high-dose potassium supplements, because this medicine can naturally raise potassium levels in your blood. Talk to your doctor or pharmacist for personalised dietary advice.

Olmesartan+Metoprolol begins working within a few hours to lower your blood pressure, but it may take up to several weeks of consistent daily use to reach its full, stable therapeutic effect. Talk to your doctor if you do not see an improvement in your blood pressure readings over time.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India.
Other Info - MET0676
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