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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Metagard CR 35 Tablet is used to treat angina pectoris (chest pain caused by coronary disease) in adult patients in combination with other medications. It contains Trimetazidine, which protects the heart cells from the effects of a reduced oxygen supply during an episode of angina. It may cause common side effects such as dizziness, headache, diarrhoea, vomiting, indigestion, abdominal pain, and nausea. Before starting Metagard CR 35 Tablet , inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Whats That

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Composition :

TRIMETAZIDINE-35MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Metagard CR 35 Tablet

Metagard CR 35 Tablet is used to treat angina pectoris (chest pain caused by coronary disease) in adult patients in combination with other medications. Angina is chest pain, which happens when the heart does not receive an adequate supply of oxygen.

Metagard CR 35 Tablet contains Trimetazidine, which protects the heart cells from the effects of a reduced oxygen supply during an episode of angina.

Metagard CR 35 Tablet may cause side effects such as dizziness, headache, diarrhoea, vomiting, indigestion, abdominal pain, and nausea. If any of these side effects persist or worsen, consult your doctor.

Do not take Metagard CR 35 Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your medical conditions and medications to prevent any potential interactions.

Uses of Metagard CR 35 Tablet

Metagard CR 35 Tablet is used to treat angina. The detailed uses of Metagard CR 35 Tablet are as follows:

  • Treatment of angina: It is used to treat stable angina pectoris (chest pain caused by reduced blood flow to the heart) in adults.
  • Add-on therapy: It is used in addition to other medicines when first-line antianginal medications are not effective or are not well tolerated.
  • Lowers angina frequency: It helps reduce the frequency and severity of angina attacks, improving exercise tolerance and quality of life in patients with chronic heart disease.

Directions for Use

  • Take Metagard CR 35 Tablet with food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Metagard CR 35 Tablet as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

  • Metagard CR 35 Tablet is used to treat angina pectoris (chest pain) in adult patients.
  • It is indicated as an add-on therapy to relieve chest pain caused by reduced blood flow to the heart, especially in patients who do not respond well to or cannot tolerate first-line antianginal drugs.
  • It helps preserve energy production in heart cells during episodes of low oxygen (ischemia), reducing damage caused by oxygen deprivation.
  • Metagard CR 35 Tablet enhances the heart’s tolerance to stress by maintaining cellular function during oxygen shortages.
  • It improves their physical activity levels and overall quality of life.

How Metagard CR 35 Tablet Works

Metagard CR 35 Tablet contains Trimetazidine, which protects the heart cells from the effects of a reduced oxygen supply during an episode of angina. Thereby, it helps treat angina.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Metagard CR 35 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink fluids: Water, clear broth, or electrolyte-rich beverages.
  • Follow a balanced diet, which would be rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.
  • Mindfulness: Manage stress with meditation, deep breathing or yoga.
  • Stay away from smoke, dust and other irritants.
  • Get adequate rest to facilitate recovery.
  • Wash hands and avoid close contact, do not share personal items.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Metagard CR 35 Tablet

Do not take more than the prescribed dose of Metagard CR 35 Tablet as it may cause an overdose, leading to unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Metagard CR 35 Tablet if you are allergic to any of its ingredients, or if you have Parkinson's disease, or severe kidney problems.
  • Metagard CR 35 Tablet is not a cure for angina attacks, and should not be used as a treatment for unstable angina or heart attack.
  • Inform your doctor if you have kidney or liver problems, close-angle glaucoma, trembling, rigid posture, slow movements, or a shuffling, unbalanced walk.
  • Consult your doctor if you are pregnant or breast-feeding.
  • In the event of an angina attack, tell your doctor, as your treatment may need to be re-evaluated.
  • Metagard CR 35 Tablet is not recommended for children under 18.
  • This medicine may cause dizziness, affecting your ability to drive.
  • Let your doctor know if you are taking any other medications, including supplements or herbal products.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet rich in soluble fibre like beans, legumes, whole grains, flax, apples, and citrus fruits.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, fish, and low in red meat and most dairy.
  • Try to give priority to more fruits and veggies in your daily meals as these contain antioxidants.
  • Minimise the intake of added sugar. The American Heart Association (ADA) recommends that one should not eat more than 100 calories (25 grams) of added sugar for women and children, and no more than 150 calories (37.5 grams) for men every day.
  • The American Heart Association recommends that sodium chloride intake (table salt) should not exceed 2,300 mg per day as part of a healthy eating pattern.
  • As a precautionary measure, do not consume alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIANGINALS
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Alcohol

Unsafe

Metagard CR 35 Tablet may cause dizziness when alcohol is taken. Therefore, avoid alcohol consumption.

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Pregnancy

Caution

Please consult your doctor if you are pregnant.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding.

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Driving

Caution

Metagard CR 35 Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Metagard CR 35 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Metagard CR 35 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Metagard CR 35 Tablet is not recommended for children below 18 years of age as the safety and effectiveness have not been established.

Have a query?

FAQs

Metagard CR 35 Tablet is used to prevent an attack of angina pectoris (chest pain caused by coronary disease) in adult patients in combination with other medications.

Metagard CR 35 Tablet decreases the body's oxygen requirement by shifting metabolism from fats to glucose, increasing the rate at which glucose is broken down. Hence, the heart works efficiently and requires less oxygen.

No, Metagard CR 35 Tablet does not stop acute attacks (sudden attack) of angina. Metagard CR 35 Tablet helps prevent a new attack.

Usually, Metagard CR 35 Tablet is prescribed for long-term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.

No, Metagard CR 35 Tablet should not be stopped even if you feel better, as it worsens your condition. Please consult your doctor if you feel better and do as advised.

Yes, Metagard CR 35 Tablet can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.

Metagard CR 35 Tablet should be used with caution in elderly patients. Please consult the doctor before using Metagard CR 35 Tablet before using Metagard CR 35 Tablet in geriatric patients.

Metagard CR 35 Tablet is not recommended for use in children. Please consult the doctor if you have any concerns.

No, Metagard CR 35 Tablet may not cause weight gain. Follow a healthy diet and exercise regularly to maintain proper weight.

No, Metagard CR 35 Tablet is not a beta blocker. It is an anti-anginal medicine.

Metagard CR 35 Tablet should not be taken by people who are allergic to any of its components. Inform the doctor if you have severe kidney disease or Parkinsons disease.

Metagard CR 35 Tablet might increase the risk of falling due to a drop in blood pressure or instability while walking. Be cautious while getting up from a sitting/lying position.

Metagard CR 35 Tablet should be swallowed as a whole with water; do not crush or chew it.

The possible side effects of Metagard CR 35 Tablet are dizziness, headache, diarrhoea, vomiting, indigestion, abdominal pain, and feeling sick. In case of any discomfort, speak with a doctor.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - MET0136

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