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Metaglez Forte Tablet is used to treat type 2 diabetes mellitus. It helps maintain stable blood sugar levels and lowers the risk of diabetes-related complications when used along with a healthy diet and regular exercise.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Metaglez Forte Tablet

Metaglez Forte Tablet is a prescription medicine used to manage high blood sugar in adults with type 2 diabetes. It is prescribed alongside diet and exercise to help improve blood sugar control and prevent long-term complications.

To get the best results, you must take Metaglez Forte Tablet consistently every day, exactly as prescribed by your healthcare provider. It is typically taken with meals, usually with breakfast or your first main meal of the day, to reduce the chance of an upset stomach. Incorporating a balanced diet and regular physical activity into your daily routine is essential to support the effects of this medicine.

While taking Metaglez Forte Tablet , you may experience mild side effects like a temporary upset stomach or a metallic taste in your mouth. However, you must contact your doctor immediately if you experience severe symptoms, such as unusual muscle pain, trouble breathing, or extreme fatigue, which could indicate a rare but serious build-up of acid in your blood.

Talk to your doctor before starting this medicine if you have a history of kidney issues, liver damage, or heart failure. Do not take this if you have severe kidney disease, severe liver damage, or metabolic acidosis.

This medicine can interact with other substances, such as alcohol, which can significantly increase your risk of low blood sugar or serious blood acid complications. If you are pregnant, breastfeeding, or over the age of 65, consult your doctor or pharmacist to ensure this medicine is safe for your specific situation.

Uses of Metaglez Forte Tablet

Metaglez Forte Tablet is used to help control blood sugar levels in adults with type 2 diabetes mellitus when lifestyle measures alone are not sufficient.

  • Type 2 Diabetes Mellitus: Metaglez Forte Tablet helps improve blood sugar control by increasing insulin release from the pancreas and reducing the amount of glucose produced by the liver. It is used alongside a healthy diet and regular exercise to maintain stable blood sugar levels.
     

Key Benefits

Metaglez Forte Tablet combines two complementary diabetes medicines to provide effective blood sugar management and long-term health benefits.

  • Provides effective blood sugar control: It helps keep blood glucose levels within the target range throughout the day, reducing fluctuations in blood sugar.
  • Targets multiple causes of high blood sugar: The combination works through different mechanisms to improve overall glucose control more effectively than either medicine alone in many patients.
  • Reduces the risk of diabetes complications: Maintaining healthy blood sugar levels helps lower the risk of complications affecting the nerves, kidneys, eyes, and cardiovascular system.
  • Supports long-term diabetes management: Consistent blood sugar control can help improve overall health and reduce the likelihood of diabetes-related hospitalisations.
  • Offers the convenience of combination therapy: By combining two medications into a single tablet, it may simplify treatment and improve adherence to therapy.
  • Promotes an active and healthy lifestyle: Better glucose control can help improve energy levels and support participation in daily activities and regular physical exercise.
     
Side effects of Metaglez Forte Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

To achieve the best blood sugar control, take Metaglez Forte Tablet exactly as prescribed by your doctor and follow your treatment plan consistently.

  • Swallow the tablet whole with a full glass of water.
  • Take the medication with food to help reduce the risk of stomach upset and improve tolerability.
  • Try to take your dose at the same time each day to maintain consistent blood sugar control and establish a regular routine.
  • Follow your doctor's instructions regarding the timing and dosage of your medication.
  • Monitor your blood sugar levels as recommended by your healthcare provider.
  • Continue following a healthy diet and regular exercise programme while taking this medication.
  • Do not change your dose or stop taking the medicine without consulting your doctor, even if you feel well.
     

How Metaglez Forte Tablet Works

This combination medicine contains two active ingredients that work in different ways to help your body manage blood sugar levels. The first active ingredient works by encouraging your pancreas to release more insulin. Insulin is the hormone responsible for moving sugar out of your bloodstream and into your cells where it can be used for energy. By increasing insulin release, this component helps lower sudden spikes in blood sugar, especially after meals. The second active ingredient works in two ways: it decreases the amount of sugar that your liver naturally produces and releases into your blood, and it helps your muscles use the insulin your body already makes more efficiently. Together, these two mechanisms provide a highly effective, coordinated approach to maintaining healthy blood glucose levels throughout the day.
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Metaglez Forte Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Caution

Metaglez Forte Tablet may affect the fetus during pregnancy. Please consult your doctor before starting Metaglez Forte Tablet .

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Breast Feeding

Caution

There is no sufficient data on how Metaglez Forte Tablet affects breastfeeding. It is safe to seek medical advice before you start Metaglez Forte Tablet if you are lactating.

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Driving

Caution

Your driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you may experience dizziness or drowsiness.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment when you are prescribed Metaglez Forte Tablet .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases when you are prescribed Metaglez Forte Tablet .

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Children

Caution

Please seek advice from a doctor before giving Metaglez Forte Tablet to a child.

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Heart

Consult your doctor

Metaglez Forte Tablet should be used with caution if you have any cardiac problems. This medicine is contraindicated in patients with severe heart failure.

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Geriatrics

Caution

Caution should be exercised in geriatric patients while taking Metaglez Forte Tablet .

What if I have taken an overdose of Metaglez Forte Tablet

An overdose of Metaglez Forte Tablet may result in lactic acidosis or severe low blood sugar. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Consistent carbohydrate intake: Spread your carbohydrate intake evenly across your meals throughout the day to avoid sudden spikes or drops in blood sugar.
  • Regular physical activity: Aim for moderate exercise, such as brisk walking, for at least 30 minutes on most days of the week, as this helps your body use insulin more effectively.
  • Stay hydrated: Drink plenty of water throughout the day to support your kidney function and help your body process the medication safely.
  • Monitor blood sugar: Keep a regular log of your blood sugar readings as recommended by your healthcare provider to track how well your treatment plan is working.
     
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How Soon It Starts Working

The time required for Metaglez Forte Tablet to start to work: The time required for Metaglez Forte Tablet to show its action is not clinically established.

The time for which the effects of Metaglez Forte Tablet last: The duration of action for Metaglez Forte Tablet is not clinically established.

What if you forget to take Metaglez Forte Tablet

If you miss a dose of Metaglez Forte Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

•Store Metaglez Forte Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F and 77°F). •Keep the medication in its original container with the lid tightly closed.

Drug Warnings

  • Carry a Source of Fast-Acting Sugar: Always carry a fast-acting source of sugar, such as glucose tablets, fruit juice, or hard candy, in case you experience sudden symptoms of low blood sugar.
  • Monitor Blood Sugar More Frequently During Special Situations: Check your blood sugar levels more frequently when you are sick, under unusual stress, or travelling across different time zones.
  • Inform Healthcare Providers Before Procedures: Inform your doctor or dentist that you are taking Metaglez Forte Tablet before undergoing any surgery or medical procedures.
  • Follow Precautions for Contrast Dye Procedures: If you need to have a scan or X-ray that involves contrast dye, you must temporarily stop taking Metaglez Forte Tablet before the procedure and wait at least 48 hours afterward to restart. Talk to your doctor for specific instructions.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Metaglez Forte Tablet may interact with medications that affect blood sugar levels or alter the body's response to treatment.

  • Beta-blockers and certain blood pressure medications: These medicines may mask some warning signs of low blood sugar, such as a rapid heartbeat, making hypoglycaemia more difficult to recognise.
  • Diuretics (water tablets): Certain diuretics can raise blood sugar levels and may reduce the effectiveness of Metaglez Forte Tablet .
  • Corticosteroids: Steroid medications may increase blood glucose levels, making diabetes more difficult to control.
  • Other diabetes medications, including insulin: Using Metaglez Forte Tablet together with other blood sugar-lowering medicines can increase the risk of hypoglycaemia (low blood sugar).

Drug-Food Interactions

Certain foods and beverages may affect the safety and effectiveness of Metaglez Forte Tablet .

  • Alcohol: Excessive alcohol consumption can increase the risk of low blood sugar and may also raise the risk of lactic acidosis, a rare but serious complication associated with metformin.

Drug-Disease Interactions

Certain medical conditions may require special precautions or make this medication unsuitable.

  • Kidney disease: Reduced kidney function can increase the accumulation of metformin in the body and raise the risk of serious side effects. Severe kidney impairment is generally a contraindication to treatment.
  • Liver disease: Significant liver impairment may increase the risk of lactic acidosis and affect blood sugar regulation.
  • Diabetic ketoacidosis (DKA): Metaglez Forte Tablet should not be used to treat diabetic ketoacidosis, which requires immediate medical attention and specialised treatment.
  • Conditions associated with poor oxygen supply: Severe heart failure, shock, or serious respiratory illness may increase the risk of lactic acidosis and require careful medical evaluation before using this medication.
     
Critical

Drug-Drug Interactions

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How does the drug interact with Metaglez Forte Tablet:
Co-administration of Glipizide with Gatifloxacin may affect both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Glipizide can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Metformin and Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Metformin with Metrizamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Iopamidol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iopamidol is not recommended, consult a doctor before taking it. Do not stop using your medications without talking to a doctor.
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Iodixanol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iodixanol is not recommended, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Iomeprol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iomeprol is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Iopromide with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Iopromide with Metformin is not recommended, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
Severe
How does the drug interact with Metaglez Forte Tablet:
Taking Cinoxacin with Glipizide may affect blood glucose levels (both hyperglycemia - high blood glucose and, less frequently, hypoglycemia - low blood glucose).

How to manage the interaction:
Although there is a possible interaction Glipizide can be taken with Cinoxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as dizziness, drowsiness, headache, nervousness, confusion, tremors, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar like increased urination, increased thirst, or increased hunger. Do not discontinue the medications without consulting a doctor.
Severe
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Metformin with Methazolamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Metformin and Methazolamide, you can take these medicines together if prescribed by a doctor. However, if you have symptoms such as weakness, muscle pain, respiratory distress, fatigue, loss of appetite, slow or irregular heartbeat, breathing difficulty, or chills, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Ofloxacin and Glipizide can sometimes have an effect on blood glucose levels.

How to manage the interaction:
Although combining Ofloxacin and Glipizide can lead to an interaction, they can be taken on a doctor's advice. If you experience any symptoms of hypoglycemia (headache, dizziness, sleepiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweat, palpitation, and rapid heartbeat) or hyperglycemia (increased thirst, hunger, and urination), consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metaglez Forte Tablet:
Taking Voriconazole and Glipizide may increase the blood levels and effects of Glipizide leading to hypoglycemia (low blood sugar levels).

How to manage the interaction:
Although there is a possible interaction Glipizide can be taken with Voriconazole if prescribed by the doctor. Consult a prescriber if you experience symptoms of low blood sugar such as dizziness, drowsiness, headache, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Metaglez Forte Tablet is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Metaglez Forte Tablet promotes insulin secretion from the beta cells of the pancreas and reduces the glucose output from the liver. It works by reducing the sugar production by cells in the liver and delaying sugar absorption from the intestines.
You are not recommended to stop taking Metaglez Forte Tablet on your own, as discontinuing Metaglez Forte Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Metaglez Forte Tablet , please consult your doctor so that alternative medicine may be prescribed.
In type 1 diabetes, the body does not produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completely. In type 2 diabetes, though islet cells are working, the body does not respond to insulin as the body becomes resistant to insulin.
Metaglez Forte Tablet should preferably be taken with meals. Taking it with food helps reduce gastrointestinal side effects such as nausea, stomach discomfort, and diarrhoea while helping maintain blood sugar control.
Metaglez Forte Tablet contains two anti-diabetic drugs, namely Glipizide and Metformin, as its active ingredients.
Metaglez Forte Tablet may cause side effects such as low blood sugar, nausea, indigestion, headache, diarrhoea, stomach pain, or blurred vision. If these side effects persist or worsen, please consult your doctor.
Yes, Metaglez Forte Tablet can cause hypoglycemia (low blood sugar). Symptoms may include hunger, dizziness, sweating, headache, nausea, irritability, shakiness, anxiety, or a fast heartbeat. The risk increases if you miss or delay meals, exercise more than usual, consume alcohol, or take other antidiabetic medicines. If you experience symptoms of low blood sugar, consume a fast-acting source of sugar such as fruit juice, glucose tablets, or candy. Regular blood sugar monitoring is recommended.
Yes, the use of Metaglez Forte Tablet can cause lactic acidosis. It is a medical emergency which occurs due to increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the metformin and thus, it is contraindicated in patients with underlying kidney disease, elderly patients or who consume large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, feeling of cold in arms and legs, dizziness, tiredness, difficulty in breathing, stomach pain, nausea, vomiting or slow heart rate. If you experience these symptoms, stop taking Metaglez Forte Tablet and consult your doctor immediately.
Yes, long term use of Metaglez Forte Tablet can cause Vitamin B12 deficiency. It interferes with absorption of Vitamin B12 in the stomach. If untreated, it may cause nerve problems and anemia and the patient may feel numbness and tingling sensation in the hands and feet, urinary problems, weakness, change in mental status and difficulty in maintaining balance (ataxia). To prevent such problems, some researchers recommend an intake of Vitamin B12 from external sources at least once a year.
Metaglez Forte Tablet is contraindicated in patients with known allergy to any of its components or excipients. Also, it should be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.
No. Alcohol should be avoided or strictly limited while taking Metaglez Forte Tablet because it can increase the risk of hypoglycaemia (low blood sugar) and lactic acidosis, a rare but serious medical condition associated with metformin.
Store Metaglez Forte Tablet at room temperature protected from moisture. Keep it out of reach of children.
Metaglez Forte Tablet overdose can result in serious complications such as hypoglycaemia (low blood sugar) or lactic acidosis. Hence, if you suspect an overdose, seek medical attention immediately.
Take Metaglez Forte Tablet exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water. Do not break, crush, or chew it, as this may affect how the medicine works.
If you experience signs of low blood sugar, such as sweating, shakiness, or dizziness, immediately consume 15 grams of fast-acting sugar (like fruit juice, soda, or hard candy). Wait 15 minutes, check your blood sugar again, and repeat if necessary. Talk to your doctor if this happens frequently.
While some of the active ingredients in this medicine are considered weight-neutral or may support mild weight reduction when paired with diet and exercise, Metaglez Forte Tablet is not a weight-loss medication. Talk to your doctor for personalized weight management advice.
The medicine begins working shortly after your first few doses to help manage blood sugar spikes after meals. However, it may take several weeks of consistent use, alongside diet and lifestyle changes, to see the full benefit in your routine lab tests. Talk to your doctor to monitor your progress.
If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking Metaglez Forte Tablet . This medicine is generally not preferred during pregnancy or breastfeeding, and your doctor may recommend alternative treatments that are considered safer.
Yes. Your doctor will regularly order blood tests to monitor your long-term blood sugar control (HbA1c) and check your kidney and liver function to ensure the medicine remains safe for you to use. Talk to your doctor about how often you need these tests.

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Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - MET0082
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