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compositionComposition:METOPROLOL SUCCINATE-50MG
prescription
Prescription Medicine
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Metbio 50 Tablet ER belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as heart attack and stroke. This medicine suppresses the contraction of blood vessels and promotes smooth blood flow. It also alters the response to nerve impulses in the heart, thereby making the heart pump blood more easily. Common side effects include dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

METOPROLOL SUCCINATE-50MG

Manufacturer/Marketer :

Bio Health Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Metbio 50 Tablet ER

Metbio 50 Tablet ER is an extended-release prescription tablet used to treat high blood pressure, chest pain (angina), and to improve survival rates after a heart attack. It is also prescribed to help manage stable, long-term heart failure. By helping your cardiovascular system work more efficiently, Metbio 50 Tablet ER protects your heart from unnecessary strain.

To get the best results, you should take Metbio 50 Tablet ER consistently at the same time every day. You can take Metbio 50 Tablet ER with food or on an empty stomach, but it is best to choose one way and stick to it daily. Making healthy lifestyle choices, such as eating a low-salt diet, staying moderately active, and managing stress, can greatly improve your treatment outcomes.

While taking Metbio 50 Tablet ER, you may experience some common, mild side effects like feeling tired, dizzy, or noticing a slower heartbeat. However, you should consult your doctor immediately if you experience serious side effects like severe shortness of breath, sudden weight gain, or fainting. Always monitor how you feel and share any changes with your healthcare team.

Before you begin taking this medication, talk to your doctor if you have a history of asthma, severe blood circulation problems, liver damage, or diabetes. Do not take this if you have certain severe heart conditions, such as a dangerously slow heart rate, severe heart block, or cardiogenic shock.

Metbio 50 Tablet ER can interact with other blood pressure drugs, certain antidepressants, alcohol, and tobacco, which can cause your blood pressure or heart rate to drop too low. If you are pregnant, breastfeeding, planning a pregnancy, or are an older adult, you should consult your doctor or pharmacist to make sure Metbio 50 Tablet ER is safe for you.

Uses of Metbio 50 Tablet ER

Metbio 50 Tablet ER is used in the treatment of high blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorders (arrhythmias), heart failure, and heart attack (myocardial infarction). The detailed uses of Metbio 50 Tablet ER are as follows:

• High Blood Pressure (Hypertension): Metbio 50 Tablet ER helps lower elevated blood pressure, reducing the risk of complications such as stroke, heart attack, and kidney damage.
• Chest Pain (Angina Pectoris): Metbio 50 Tablet ER helps prevent chest pain by reducing the workload on the heart and decreasing its oxygen demand.
• Heart Rhythm Disorders (Arrhythmias): Metbio 50 Tablet ER helps control abnormal heart rhythms and slows a rapid heartbeat, helping maintain a more regular heart rate.
• Heart Failure: Metbio 50 Tablet ER is used alongside other medicines to treat stable heart failure, helping improve the heart's pumping ability and reducing the risk of hospitalization.
• Post-Heart Attack Recovery: Metbio 50 Tablet ER is prescribed after a heart attack to help protect the heart muscle and reduce the risk of future cardiovascular events.

Key Benefits

Metbio 50 Tablet ER helps support heart health by lowering blood pressure, reducing the workload on the heart, and improving overall cardiovascular function. Regular use can help manage several heart-related conditions and improve quality of life.

Benefits may include:

  • Helps lower and maintain healthy blood pressure levels, protecting the heart, brain, and kidneys from long-term damage.
  • Helps prevent episodes of chest pain (angina), allowing for greater comfort during physical activity.
  • Supports the management of stable heart failure by helping the heart pump more efficiently.
  • May reduce symptoms such as shortness of breath, fatigue, and reduced exercise tolerance.
  • Helps lower the risk of certain cardiovascular complications when taken as prescribed.
  • Promotes long-term heart health and supports a more active and comfortable daily life.

Directions for Use

  • Metbio 50 Tablet ER can be taken with or without food, or as advised by your doctor.
  • Generally, it is recommended to be taken once daily. Follow your doctor's instructions regarding dosage and timing for optimal results.
  • Swallow Metbio 50 Tablet ER as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Metbio 50 Tablet ER Works

Metbio 50 Tablet ER belongs to a group of medicines known as beta-blockers. It works by specifically targeting certain receptors in your heart muscle. By blocking the action of natural stress chemicals like adrenaline, it slows down your heart rate and allows your heart to beat with less force. When your heart beats more slowly and with less effort, the pressure inside your blood vessels drops. This makes it much easier for your heart to pump blood throughout your entire body, ensuring your vital organs get a steady supply of oxygen without overworking your heart muscle.
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Alcohol

Unsafe

Alcohol might increase the blood pressure-lowering effect of Metbio 50 Tablet ER. It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Metbio 50 Tablet ER.

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Pregnancy

Unsafe

Metbio 50 Tablet ER belongs to pregnancy category C. Metbio 50 Tablet ER is not recommended for use during pregnancy. If you are pregnant, think you are pregnant or planning for pregnancy, consult your doctor.

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Breast Feeding

Caution

Metbio 50 Tablet ER may pass into breastmilk. Consult a doctor before taking Metbio 50 Tablet ER if you are breastfeeding.

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Driving

Caution

Metbio 50 Tablet ER may cause dizziness and tiredness. Therefore, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Metbio 50 Tablet ER if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Metbio 50 Tablet ER if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Metbio 50 Tablet ER is not recommended in children as the safety and efficacy have not been established.

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Heart

Caution

Metbio 50 Tablet ER should be taken with caution in patients with heart problems. Therefore, please talk to your doctor before using Metbio 50 Tablet ER.

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Geriatrics

Caution

Metbio 50 Tablet ER should be given at a lower dose for elderly patients to minimize risks, as advised by a healthcare professional.

What if I have taken an overdose of Metbio 50 Tablet ER

If you take too much of Metbio 50 Tablet ER, seek immediate medical attention or call emergency services. An overdose can cause your heart rate and blood pressure to drop to dangerously low levels, leading to severe dizziness, fainting, or breathing difficulties.

Diet & Lifestyle Advise

  • Limit your salt intake: Reduce your daily sodium consumption, as excess salt can cause fluid retention, raise blood pressure, and increase the workload on your heart.
  • Limit alcohol consumption: Avoid drinking excessive amounts of alcohol, as it may interfere with the effects of Metbio 50 Tablet ER and increase the risk of low blood pressure and dizziness.
  • Stay physically active: Engage in regular, moderate-intensity activities such as brisk walking or swimming, but consult your doctor before starting a new exercise program, as Metbio 50 Tablet ER can affect your heart rate during physical activity.
  • Avoid smoking: Seek support to quit smoking, as nicotine can constrict blood vessels and increase heart rate, reducing the benefits of Metbio 50 Tablet ER.
  • Monitor your blood pressure and heart rate: Check your blood pressure and pulse regularly at home and maintain a record to share with your doctor during follow-up visits.
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How Soon It Starts Working

The time required for Metbio 50 Tablet ER to start to work: Metbio 50 Tablet ER ideally shows its action within 1 hour after administration. The time for which the effects of Metbio 50 Tablet ER last: The effect of Metbio 50 Tablet ER lasts for 12 hours.

What if you forget to take Metbio 50 Tablet ER

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose completely and take your next tablet at your regular time. Do not take a double dose to make up for a missed one.

Storage

•Store Metbio 50 Tablet ER tablets at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).•Keep Metbio 50 Tablet ER in a secure place, completely out of the reach and sight of children and pets.

Drug Warnings

  • Inspect Metbio 50 Tablet ER before use: Do not take Metbio 50 Tablet ER if the tablets are discolored, chipped, crumbling, or otherwise damaged.
  • Use caution during activities requiring alertness: Metbio 50 Tablet ER may cause dizziness or drowsiness, especially when starting treatment. Avoid driving, operating machinery, or performing hazardous tasks until you know how Metbio 50 Tablet ER affects you.
  • Monitor blood sugar if you have diabetes: Metbio 50 Tablet ER can mask some warning signs of low blood sugar, such as a rapid heartbeat or palpitations. Check your blood glucose regularly if you have diabetes.
  • Inform healthcare providers before procedures: Tell your surgeon, dentist, anesthesiologist, or other healthcare professionals that you are taking Metbio 50 Tablet ER before any medical, surgical, or dental procedure.
  • Rise slowly to prevent dizziness: Stand up gradually from a sitting or lying position to help reduce the risk of dizziness, lightheadedness, and falls.

Drug-Drug Interactions

verifiedApollotooltip
  • Calcium channel blockers (e.g., diltiazem, verapamil): Taking these medicines alongside Metbio 50 Tablet ER may cause your heart rate or blood pressure to drop too low.
  • Antidepressants (e.g., fluoxetine, paroxetine): These medicines may increase the amount of Metbio 50 Tablet ER in the body and raise the risk of side effects.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen): Taking these medicines with Metbio 50 Tablet ER may reduce its blood pressure-lowering effect.
Metoprolol SuccinateAtazanavir
Severe
Metoprolol SuccinateDiltiazem
Severe

Drug-Drug Interactions

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Metoprolol SuccinateAtazanavir
Severe
How does the drug interact with Metbio 50 Tablet ER:
Taking Metbio 50 Tablet ER with Atazanavir together can increase the risk of abnormal heart rhythm

How to manage the interaction:
Taking Metbio 50 Tablet ER with Atazanavir together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Metoprolol SuccinateDiltiazem
Severe
How does the drug interact with Metbio 50 Tablet ER:
Taking Metoprolol with Diltiazem together can cause increased side effects.

How to manage the interaction:
There may be a possibility of interaction between Diltiazem and Metbio 50 Tablet ER, but it can be taken if prescribed by a doctor. However, if you notice fatigue, a headache, dizziness, swelling of the hands and feet, difficulty breathing, chest pain, an irregular heartbeat, make sure to contact a doctor. Do not stop using any medications without a doctor's advice.
Metoprolol SuccinateSaquinavir
Severe
How does the drug interact with Metbio 50 Tablet ER:
Using saquinavir together with metoprolol can increase the risk of an irregular heart rhythm

How to manage the interaction:
Co-administration of Metbio 50 Tablet ER with Saquinavir can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Metoprolol SuccinateDisopyramide
Severe
How does the drug interact with Metbio 50 Tablet ER:
Co-administration of Disopyramide with Metbio 50 Tablet ER can increase the side effects of disopyramide.

How to manage the interaction:
Although taking Metbio 50 Tablet ER and Disopyramide together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fainting, palpitations, slow or fast pulse, or irregular heartbeats, consult a doctor. Do not stop using any medications without talking to a doctor.
Metoprolol SuccinateRitodrine
Severe
How does the drug interact with Metbio 50 Tablet ER:
Co-administration of Ritodrine with Metbio 50 Tablet ER can decrease the effectiveness of both medications.

How to manage the interaction:
Although taking Metbio 50 Tablet ER and Ritodrine together can cause an interaction, it can be taken if a doctor has suggested it. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.
Metoprolol SuccinateCeritinib
Severe
How does the drug interact with Metbio 50 Tablet ER:
Taking Metoprolol with Ceritinib together increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Metbio 50 Tablet ER and Ceritinib, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Metoprolol SuccinateVerapamil
Severe
How does the drug interact with Metbio 50 Tablet ER:
Co-administration of verapamil with Metbio 50 Tablet ER can increase the risk of side effects.

How to manage the interaction:
Although taking verapamil and Metbio 50 Tablet ER together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Metoprolol SuccinateTheophylline
Severe
How does the drug interact with Metbio 50 Tablet ER:
Taking Metbio 50 Tablet ER with Theophylline, could make Metbio 50 Tablet ER less effective and enhance the effects of Theophylline.

How to manage the interaction:
Although taking Metbio 50 Tablet ER and theophylline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Metoprolol SuccinateFingolimod
Severe
How does the drug interact with Metbio 50 Tablet ER:
Co-administration of Fingolimod and Metbio 50 Tablet ER can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although taking Metbio 50 Tablet ER and Fingolimod together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Metoprolol SuccinateClonidine
Severe
How does the drug interact with Metbio 50 Tablet ER:
Co-administration of Clonidine and Metbio 50 Tablet ER together may lower the blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metbio 50 Tablet ER, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, contact a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Caffeine (e.g., coffee, energy drinks, soda): Excessive caffeine intake may reduce the heart rate-lowering effects of Metbio 50 Tablet ER.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Metbio 50 Tablet ER is used to treat high blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction).
Metbio 50 Tablet ER helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. Thereby, lowers blood pressure.
No. Do not stop taking Metbio 50 Tablet ER suddenly, even if your blood pressure has returned to normal, because the medication is helping to keep it under control. Stopping it abruptly may cause your blood pressure to rise rapidly and may increase the risk of severe chest pain, worsening heart disease, or even a heart attack. If you wish to stop or adjust your dose, consult your doctor, who will advise you on the safest approach.
Do not stop taking Metbio 50 Tablet ER without consulting your doctor, as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Metbio 50 Tablet ER for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Metbio 50 Tablet ER.
Consult your doctor before taking Metbio 50 Tablet ER if you have hyperthyroidism (overactive thyroid) as it might mask the symptoms or make it difficult to recognise the signs of thyrotoxicosis (excess thyroid hormone in the body).
Yes, but only under your doctor's supervision. Metbio 50 Tablet ER can be taken with anti-diabetic medicines; however, it may mask the warning signs of low blood sugar (such as a fast heartbeat), making hypoglycaemia harder to recognize. Regular blood glucose monitoring is recommended, and you should consult your doctor if you notice symptoms of low blood sugar.
Your doctor may probably ask you to stop taking Metbio 50 Tablet ER 24hours prior to the surgery, as it might lower blood pressure when combined with general anaesthesia. If you are due to have any surgery or are receiving an anaesthetic, inform the doctor that you are taking Metbio 50 Tablet ER.
Taking Metbio 50 Tablet ER along with multivitamin/multimineral supplements may decrease the effect of Metbio 50 Tablet ER. Therefore, maintain a gap of at least 2hours between both. However, you are advised to take Metbio 50 Tablet ER with other medicines only after consulting your doctor.
Yes, Metbio 50 Tablet ER is a selective beta-blocker, that acts on the heart muscles.
No, do not stop taking Metbio 50 Tablet ER if your blood pressure level comes in control as discontinuing suddenly may worsen the condition. Therefore, continue taking Metbio 50 Tablet ER for long as it is advised by your doctor.
No, Metbio 50 Tablet ER is not a blood thinner. Metbio 50 Tablet ER relaxes the blood vessels, and slows down the heart rate. Thereby, it reduces the workload on the heart and makes it easier to pump blood effectively.
The side effects of Metbio 50 Tablet ER include stomach pain, nausea, diarrhoea, dizziness, tiredness or headache. If these side effects persist or worsen, please consult your doctor.
Metbio 50 Tablet ER is generally safe if used as prescribed by the doctor. If this medication is stopped suddenly, it may cause harmful effects such as a sudden increase in the heart rate and affect its activity, which can be dangerous for heart failure patients and in some cases even result in a heart attack. Therefore, take Metbio 50 Tablet ER for the prescribed duration and do not stop taking it suddenly.
Metbio 50 Tablet ER belongs to the class of medicines called beta-blockers. Though their effect on sleep differs from person to person, it has been found that these medications are known to change the sleep pattern and disturb sleep in some patients. On the other hand, it has also been observed to promote better sleep in patients with increased anxiety and heart rate by calming down the nerves and heart. If you have any sleep disturbances, please consult your doctor.
No, you are recommended to avoid alcohol consumption after taking Metbio 50 Tablet ER as alcohol might increase the blood pressure-lowering effect of Metbio 50 Tablet ER and might cause increased dizziness.
Cold fingers and toes are common because Metbio 50 Tablet ER reduces blood flow to your skin and extremities. Dress warmly, wear gloves or thick socks, and avoid smoking, which can make the problem worse. If this symptom becomes painful or if your skin changes color, talk to your doctor.
Metbio 50 Tablet ER is generally not recommended during pregnancy unless the benefits outweigh the risks, as it can reduce blood flow to the placenta and affect the baby's heart rate and growth. If you are pregnant or planning to become pregnant, talk to your doctor.
Some common pain relievers, such as ibuprofen or naproxen, can reduce the effectiveness of Metbio 50 Tablet ER in lowering your blood pressure. If you need a pain reliever, acetaminophen is usually a safer option, but you should talk to your doctor.
Some people may experience mild weight gain when starting Metbio 50 Tablet ER due to fluid retention or a slightly slower metabolism. However, rapid weight gain (such as gaining 2 to 3 pounds in a single day) can be a sign of worsening heart failure and requires immediate attention. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Metoprolol Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Metoprolol - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Pil.5816 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. U.S. Food and Drug Administration (FDA). 019962S032Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  5. Metoprolol succinate [Prescribing Information]. 2010. [Accessed on 30 Apr. 2025]Check here
  6. Morris J, Dunham A Metoprolol. [Updated 2022 Oct. 2]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023Check here
  7. METOPROLOL SUCCINATE capsule, extended release [Internet]. Dailymed.nlm.nih.gov. 2025 [Accessed on 21st Nov 2025]Check here

Country of origin

India
Other Info - ME38439
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