apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:METHYLERGOMETRINE-0.125MG
prescription
Prescription Medicine
info
image icons
Methersafe Tablet is used to prevent and control postpartum haemorrhage. This medicine contains methylergometrine, which increases the uterus's smooth muscle contractions and thereby controls bleeding after delivery. Some of the side effects include seizures and/or headache, nausea, and vomiting.
Read more
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
Get Extra 18% Off with Coupons
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

METHYLERGOMETRINE-0.125MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Methersafe Tablet

Methersafe Tablet is used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.

Methersafe Tablet contains Methylergometrine, which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Take Methersafe Tablet exactly as prescribed by the doctor. In some cases, Methersafe Tablet may cause high blood pressure associated with seizures and/or headache, nausea, and vomiting. If the side effects persist or worsen, consult your doctor.

Do not take Methersafe Tablet if you are pregnant. Consult your doctor if you are breastfeeding. Methersafe Tablet is not recommended for children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Methersafe Tablet

Methersafe Tablet is used in the treatment of Postpartum haemorrhage. The detailed uses of Methersafe Tablet are as follows:

  • Control postpartum hemorrhage: Methersafe Tablet is primarily used to prevent and manage excessive bleeding following childbirth by stimulating strong and sustained uterine contractions.
  • Assist in uterine involution after delivery: Methersafe Tablet helps the uterus return to its normal size and tone after delivery, reducing the risk of complications related to uterine atony.

Key Benefits

Methersafe Tablet is indicated in the prevention and control of postpartum haemorrhage. It is used following delivery of the placenta for the routine management of uterine atony (soft and weak uterus after childbirth), subinvolution of the uterus, and haemorrhage. Methersafe Tablet contains Methylergometrine, a semi-synthetic ergot alkaloid which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Side effects of Methersafe Tablet
  • Stress levels should be managed by practicing yoga and meditation regularly.
  • Maintain a proper sleeping schedule.
  • Maintain a balanced diet containing low glycemic index like fruits, vegetables, proteins and grains.
  • Do not consume alcohol.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Methersafe Tablet can be taken with or without food.
  • Your healthcare provider will decide the correct dosage and frequency based on your condition.
  • Take it exactly as prescribed, usually with a full glass of water.
  • Do not crush, chew, or break the tablet. Swallow it whole as directed.
  • Do not change the dose or stop taking the medication without first consulting your doctor.

How Methersafe Tablet Works

Methersafe Tablet contains Methylergometrine, which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.
bannner image

Alcohol

Caution

It is not known if alcohol affects Methersafe Tablet. Please consult your doctor.

bannner image

Pregnancy

Unsafe

Methersafe Tablet is not recommended for use during pregnancy.

bannner image

Breast Feeding

Caution

Methersafe Tablet passes into breastmilk. Avoid breastfeeding during treatment with Methersafe Tablet and for 12 hours after the last dose. Please consult your doctor if you have any concerns.

bannner image

Driving

Caution

It is not known if Methersafe Tablet affects your ability to drive.

bannner image

Liver

Caution

Caution should be exercised while using Methersafe Tablet in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Caution should be exercised while using Methersafe Tablet in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

bannner image

Children

Unsafe

Methersafe Tablet is not recommended for children as safety and effectiveness have not been established.

bannner image

Heart

Caution

Methersafe Tablet may not be safe for patients with heart conditions. Please inform your doctor about any heart-related issues before using Methersafe Tablet.

bannner image

Geriatrics

Caution

Methersafe Tablet should be used with caution in elderly patients, as they may be more susceptible to side effects. Dose adjustments may be necessary. Always consult a healthcare professional before use.

What if I have taken an overdose of Methersafe Tablet

Avoid taking more than the prescribed dose of Methersafe Tablet as it can cause serious side effects. Overdose of Methersafe Tablet include severe headache, severe dizziness, seizures, slow/shallow breathing. Seek immediate medical attention if you observe any of these side effects.

Diet & Lifestyle Advise

  • Include high-fibre foods such as fruits and whole grains.
  • Drink plenty of fluids such as water, fruit juices, and milk.
  • Limit processed/packaged foods, high salt/sugary foods and saturated fats.
  • Get plenty of rest.
  • Eat healthy meals and exercise appropriately.
health query

Have a query?

How Soon It Starts Working

The time required for Methersafe Tablet to start to work: Methersafe Tablet ideally shows its action within 5 to 10 minutes after administration. The time for which the effects of Methersafe Tablet last: The effect of Methersafe Tablet lasts for 3 hours.

What if you forget to take Methersafe Tablet

If you miss a dose of Methersafe Tablet, take it as soon as you remember, unless it’s almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for the missed dose. Always consult your doctor if you are unsure about how to proceed.

Storage

• Store in a cool and dry place away from sunlight. • Keep Methersafe Tablet out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not take Methersafe Tablet if you are allergic to any of its components, if you have high blood pressure, toxaemia (a complication of pregnancy characterised by high blood pressure), or if you are pregnant. Inform your doctor if you have coronary artery disease, sepsis, vascular disease, or liver or kidney impairment. Consult your doctor if you are breastfeeding. The safety and effectiveness of Methersafe Tablet in children have not been established. Let your doctor know if you are taking prescription/non-prescription medicines, including herbal products and supplements.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Inform the doctor if you are taking ergot alkaloids (dihydroergotamine, ergotamine), macrolide antibiotics (erythromycin, troleandomycin, clarithromycin), HIV protease or reverse transcriptase inhibitors (ritonavir, indinavir, nelfinavir, delavirdine), antifungals (ketoconazole, itraconazole, voriconazole).

Drug-Food Interactions: Avoid consuming grapefruit juice whilst on treatment with Methersafe Tablet.

Drug-Disease Interactions: Inform the doctor if you have high blood pressure/hypertension, toxaemia (a complication of pregnancy characterised by high blood pressure), or if you are pregnant.

MethylergometrineVoriconazole
Critical
MethylergometrineKetoconazole
Critical

Drug-Drug Interactions

Login/Sign Up

MethylergometrineVoriconazole
Critical
How does the drug interact with Methersafe Tablet:
Coadministration of Methersafe Tablet with Voriconazole may increase the blood level of Methersafe Tablet.

How to manage the interaction:
Although Methersafe Tablet with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineKetoconazole
Critical
How does the drug interact with Methersafe Tablet:
Using Ketoconazole with Methersafe Tablet can increase the concentration of Methersafe Tablet, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Methersafe Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineGlyceryl trinitrate
Critical
How does the drug interact with Methersafe Tablet:
Coadministration of Methersafe Tablet with Glyceryl trinitrate can increase the levels and side effects of Methersafe Tablet.

How to manage the interaction:
Taking Methersafe Tablet with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
MethylergometrineItraconazole
Critical
How does the drug interact with Methersafe Tablet:
Co-administration of Methersafe Tablet and Itraconazole may increase the blood levels of Methersafe Tablet.

How to manage the interaction:
Methersafe Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
MethylergometrineRitonavir
Critical
How does the drug interact with Methersafe Tablet:
Taking Methersafe Tablet with Ritonavir can significantly increase the blood levels and effects of Methersafe Tablet.

How to manage the interaction:
Taking Methersafe Tablet with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylergometrineSumatriptan
Critical
How does the drug interact with Methersafe Tablet:
Coadministration of Sumatriptan with Methersafe Tablet can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with Methersafe Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MethylergometrineClarithromycin
Critical
How does the drug interact with Methersafe Tablet:
When Methersafe Tablet is taken with Clarithromycin, the amount of Methersafe Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with Methersafe Tablet is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
MethylergometrineEphedrine
Severe
How does the drug interact with Methersafe Tablet:
Taking Ephedrine with Methersafe Tablet may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with Methersafe Tablet may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.
MethylergometrinePhenylephrine
Severe
How does the drug interact with Methersafe Tablet:
Taking Phenylephrine with Methersafe Tablet can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with Methersafe Tablet can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

Login/Sign Up

METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of Methersafe Tablet with Grapefruit and Grapefruit may lead to an increase in the effectiveness of Methersafe Tablet. Avoid or limit grapefruit and grapefruit juice consumption with Methersafe Tablet. This can increase the risk or severity of side effects.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Methersafe Tablet is used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.
Methersafe Tablet works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.
Methersafe Tablet is not recommended for use in people with high blood pressure. Consult your doctor if you have hypertension.
Methersafe Tablet may cause nausea or vomiting as a side effect. It is not necessary for everyone taking Methersafe Tablet to experience this side effect. However, if the condition persists or worsens, consult your doctor.
Methersafe Tablet may be indicated in the management of uterine atony. Uterine atony refers to a weak and soft uterus after childbirth.
Yes, Methersafe Tablet may cause decreased milk production if taken by lactating mothers after childbirth. It is recommended to avoid breastfeeding while taking Methersafe Tablet for at least 12 hours after your last dose. Consult the doctor if you have any concerns.
Methersafe Tablet should not be used to stop uterine bleeding after child birth if the patient has high blood pressure as it may worsen hypertension. Consult the doctor if you have any concerns.
No, Methersafe Tablet should not be used to stop menstrual bleeding as it is used to manage and prevent excessive bleeding after childbirth (postpartum haemorrhage).
Methersafe Tablet should be taken with or without food as advised by the doctor based on your medical condition.
You should not take Methersafe Tablet if you are allergic to any of its ingredients. It should not be taken by individuals with high blood pressure (hypertension), or toxaemia (an abnormal condition associated with the presence of toxic substances in the bloodstream) during pregnancy.
No, breastfeeding should be avoided during treatment with Methersafe Tablet and for at least 12 hours after the final dose. Consult the doctor if you have any concerns.
Yes, Methersafe Tablet may cause an increase in blood pressure as a common side effect. Consult the doctor before taking Methersafe Tablet if you have high blood pressure.
Patients with heart disease may have an increased risk of myocardial ischemia and infarction due to methylergonovine-induced vasospasm. Consult the doctor if you have any heart problems.
The side effects of Methersafe Tablet include nausea, vomiting, headache, and hypertension (increased blood pressure) associated with seizures. Consult the doctor if any of these symptoms persist or worsen.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - ME96591
whatsapp Floating Button
Buy Now
Add to Cart