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Metholix-P Capsule is used in the treatment of neuropathic pain. It contains Pregabalin and Methylcobalamin, which decreases the pain signals and helps rejuvenate and protect damaged nerve cells. It may cause common side effects such as dizziness, drowsiness, headache, loss of appetite, nausea or vomiting, diarrhea, headache, vision problems, and sweating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Metholix-P Capsule
Metholix-P Capsule belongs to the class of medications ‘anticonvulsants’ used in the treatment of neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.
Metholix-P Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).
You should take this medicine as prescribed by your doctor. The common side-effects of Metholix-P Capsule are dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Inform your doctor if any of these side effects persist.
Do not take Metholix-P Capsule if you are allergic to ‘Pregabalin’ and ‘Methylcobalamin’ or any contents before taking Metholix-P Capsule if you have a history of heart diseases, liver or kidney disease, alcoholism, or drug abuse. It should not be used in children and adolescents below 18 years. Inform your doctor if you are pregnant and breastfeeding. Do not drive or operate heavy machinery as Metholix-P Capsule may cause dizziness or drowsiness. Metholix-P Capsule contains lactose, so inform your doctor if you have any intolerance to sugars. Do not discontinue treatment without telling your doctor.
Uses of Metholix-P Capsule
Metholix-P Capsule is used in the treatment of Neuropathic pain. The detailed uses of Metholix-P Capsule are as follows:
Directions for Use
• Take Metholix-P Capsule with or without food or as advised by a doctor. • Recommended to take the medicine twice a day, in the morning and evening or as advised by your doctor. • Swallow the medicine as a whole with glass of water. • Do not crush, break, or chew it.
Medicinal Benefits
Metholix-P Capsule is a combination of two drugs: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that affects the brain's chemicals that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels (responsible for excitatory response), thereby decreasing brain activity. This effect helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cells). Together, Metholix-P Capsule helps in providing relief from neuropathic pain and improved nerve signal conduction.
How Metholix-P Capsule Works
Storage
What if I have taken an overdose of Metholix-P Capsule
Drug Warnings
Metholix-P Capsule may increase the risk of heart failure in patients with heart diseases. It may cause dizziness and somnolence (sleepiness). So, it might increase the risk of accidental injury in elderly patients. Metholix-P Capsule may also cause temporary vision problems. However, if this condition is persistent, consult your doctor immediately. Patients with diabetes who gain weight with Metholix-P Capsule may need a change in diabetic medicines. If you notice decreased urination while taking Metholix-P Capsule , inform your doctor as Metholix-P Capsule may cause kidney failure in some cases. It may increase suicidal tendencies, though it is rare. You may experience convulsions after discontinuing Metholix-P Capsule . In such cases, inform your doctor immediately.
Drug-Drug Interactions
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Diet & Lifestyle Advise
Include food rich in vitamin B and D in your diet.
Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
Exercising regularly helps in improving overall health and combating pain.
Rest well, get plenty of sleep.
Try taking a warm bath as it can be soothing.
Avoid smoking and alcohol consumption.
Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
Acupuncture can be helpful by stimulating pressure points.
Using essential oils for massages can help increase circulation.
Habit Forming
Therapeutic Class
Product Substitutes
Alcohol
Caution
Alcohol may worsen the condition by increasing the risk of side-effects.
Pregnancy
Unsafe
Metholix-P Capsule is a category C medicine. It is not recommended for use in pregnant women unless the doctor thinks the benefits outweigh the risks.
Breast Feeding
Caution
Metholix-P Capsule should be used with caution in breastfeeding mothers unless the doctor thinks the benefits outweigh the risks.
Driving
Caution
Metholix-P Capsule may cause dizziness and drowsiness. So, avoid driving or operating heavy machinery while using Metholix-P Capsule .
Liver
Caution
Metholix-P Capsule should be used with caution in patients with liver diseases. Dose adjustments may be necessary.
Kidney
Caution
Metholix-P Capsule should be used with caution in patients with kidney diseases. Dose adjustments may be necessary
Children
Unsafe
Metholix-P Capsule is not recommended for anyone below the age of 18 years.
Have a query?
Metholix-P Capsule is used in the treatment of neuropathic pain, a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning.
Metholix-P Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Metholix-P Capsule block the brain's pain signals and protect nerve cells from further damage, thereby improving nerve signal conduction to the whole body parts. These effects help to reduce pain in patients with neuropathic pain.
Metholix-P Capsule should not be given to children and adolescents under the age of 18 years as it may increase suicidal thoughts.
Metholix-P Capsule should not be stopped abruptly as it may cause withdrawal reactions such as trouble sleeping, headache, nausea, feeling anxious, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness. Metholix-P Capsule should be stopped gradually over a minimum of 1 week.
Metholix-P Capsule can be used in patients with diabetes if they have neuropathic pain. However, inform your doctor if you notice any weight gain while using Metholix-P Capsule . Your doctor may change your diabetic medicines to stop weight gain. Also, take some measures to control weight such as eating a balanced diet and exercising regularly.
Metholix-P Capsule may cause drowsiness. So, it is advised to refrain from activities such as driving or operating heavy machinery if you feel sleepy after taking Metholix-P Capsule .
You may notice pain improvement within 2-3 days after taking Metholix-P Capsule . However, it may take 2-3 months for your symptoms to improve depending on your health condition.
Metholix-P Capsule may increase your appetite, which might make you eat more, and thus increases the risk of weight gain. However, it’s easier to prevent weight gain than losing the weight. Try to eat a healthy balanced diet. Avoid consuming high-calorie foods, such as soft drinks, chips, oily food, biscuits, cakes, and sweets. If you feel hungry between meals, do not eat junk food, instead eat vegetables, fruits, and low-calorie foods. Regular exercise helps to prevent weight gain. If you still have any concerns, discuss with your doctor.
Metholix-P Capsule may rarely cause serious side effects such as allergic reaction, suicidal thoughts or swelling of limbs (legs, hands, or feet). If you experience any signs of these side effects, discontinue Metholix-P Capsule and consult your doctor. Signs of an allergic reaction include swelling of your face, lips, mouth, tongue, gums, and neck. Allergic reactions can also lead to skin rash, difficulty breathing, hives (raised bumps) or blisters. Watch out for any changes, especially sudden changes in behaviors, mood, thoughts or feelings, or if you have suicidal thoughts.
Metholix-P Capsule may show an initial benefit after 2 weeks of taking it. However, for full benefits, it may take around 2 to 3 months or more (in some patients).
If you forget to take a dose of Metholix-P Capsule , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of toxicity and serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.
You are advised to avoid alcohol consumption while taking Metholix-P Capsule as it may increase the risk of side effects. However, if you have any concerns, please discuss with your doctor.
If you have started taking Metholix-P Capsule , you may need to see your doctor regularly. However, if the recommended doses does not improve your symptoms or if the side effects persist or worsen which affect your routine activities, consult your doctor.
Store Metholix-P Capsule at room temperature in a cool place. Protect from light and moisture. Keep it out of reach of children.
The side effects of Metholix-P Capsule include nausea, vomiting, headache, dizziness, drowsiness, increased appetite, weight gain and vision problems. If these side effects persist or worsen, please consult your doctor.
You are recommended to take Metholix-P Capsule only if it is advised by your doctor. Therefore, if you are pregnant or planning pregnancy, take your doctor’s advice.
You are recommended to avoid driving or using any tools or machines until you know how Metholix-P Capsule affects you as it may cause dizziness or drowsiness in some people.
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