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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Metpure-XL 25 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure, arrhythmia, and angina pectoris. It contains bisoprolol, which alters the response to nerve impulses in the heart, thereby making the heart pump blood more easily. Common side effects include headache, fatigue, nausea, vomiting, stomach upset, diarrhoea or constipation, abdominal pain, numbness, and cold extremities.

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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

About Metpure-XL 25 Tablet

Metpure-XL 25 Tablet is used alone or together with other medicines to treat high blood pressure (hypertension), heart-related chest pain (angina), and heart rhythm disorder (arrhythmia). Besides this, it also helps in relieving symptoms of migraine-related headaches.

Metpure-XL 25 Tablet contains S-Metoprolol Succinate, which works by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier to pump more blood around your body.

In some cases, you may experience side effects such as headache, fatigue, nausea, vomiting, stomach upset, diarrhoea or constipation, abdominal pain, numbness, and cold extremities. If the side effects are persistent, reach out to your doctor.

Do not take Metpure-XL 25 Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to prevent any interactions.

Uses of Metpure-XL 25 Tablet

Metpure-XL 25 Tablet is used to manage cardiovascular conditions by controlling blood pressure, heart rate, and workload on the heart. The detailed uses of Metpure-XL 25 Tablet are as follows:

  • Treatment of hypertension: Metpure-XL 25 Tablet lowers blood pressure, reducing the risk of heart attack and stroke.
  • Long-term management of angina pectoris: Metpure-XL 25 Tablet prevents chest pain by improving blood flow and reducing the heart’s oxygen demand.
  • Management of heart failure: Metpure-XL 25 Tablet is used to improve heart function and reduce symptoms in patients with chronic heart failure.
  • Support in arrhythmia control: Metpure-XL 25 Tablet helps in maintaining a normal heart rhythm in patients with irregular heartbeat.

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Directions for Use

  • Take Metpure-XL 25 Tablet with or without food or as advised by the doctor.
  • Generally, it is advised to take it once a day or follow your doctor's instructions on the dosage and timing of this medication to have optimal results.
  • Swallow Metpure-XL 25 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

  • Metpure-XL 25 Tablet contains S-Metoprolol Succinate, a beta-blocker used for blood pressure management.
  • It treats high blood pressure (hypertension) by reducing the workload on the heart.
  • It also helps manage chest pain (angina) and irregular heart rhythms (arrhythmia).
  • It slows down the heart rate, making it easier for the heart to pump blood effectively.
  • Metpure-XL 25 Tablet lowers blood pressure and reduces the risk of stroke, heart attack, and other cardiovascular or kidney problems.
  • It may also help relieve migraine-related headaches by improving blood flow and reducing stress on blood vessels.

How Metpure-XL 25 Tablet Works

Metpure-XL 25 Tablet contains S Metoprolol Succinate. It plays a vital role in relaxing our blood vessels by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier to pump more blood around your body. This lowers your blood pressure and helps reduce your risk of a stroke, a heart attack, other heart problems, or kidney problems in the future.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Metpure-XL 25 Tablet

Take Metpure-XL 25 Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include severe low blood pressure, nausea, vomiting, sinus bradycardia (slow heart rate), atrioventricular block (delay in transmission of an impulse from atria to ventricles), cardiogenic shock (inability of the heart to supply blood and oxygen), heart failure, bronchospasm (tightening of airway muscles), cardiac arrest (abrupt loss of heart function), cyanosis (bluish-purple colour of skin), and impairment of consciousness/coma. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Metpure-XL 25 Tablet if you are allergic (hypersensitive) to any of its ingredients.
  • Please consult your doctor before taking Metpure-XL 25 Tablet if you are pregnant or planning to conceive and breastfeed.
  • It should not be given to children less than 12 years of age.
  • You should not use the Metpure-XL 25 Tablet if you have a very slow heartbeat, a serious lung condition (like asthma), a serious heart condition (sick sinus syndrome), or a heart blockage.
  • Before taking this medicine, you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problems (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia) or low blood pressure (hypotension).
  • Inform your doctor if you have depression, previous heart failure, liver/kidney disease, thyroid hormone disorder like overactive thyroid (hyperthyroidism), adrenal gland cancer, or severe blood circulation problem (Raynaud's syndrome).
  • Let your doctor know if you are taking any other medicines.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Metpure-XL 25 Tablet:
Co-administration of verapamil with Metpure-XL 25 Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking verapamil and Metpure-XL 25 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Co-administration of Clonidine and Metpure-XL 25 Tablet together may lower the blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metpure-XL 25 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Taking Metpure-XL 25 Tablet with Atazanavir together can increase the risk of abnormal heart rhythm

How to manage the interaction:
Taking Metpure-XL 25 Tablet with Atazanavir together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Co-administration of Aminophylline with Metoprolol could reduce the effects of Metoprolol and increase the affects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Metoprolol can cause an interaction; however, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Taking Metpure-XL 25 Tablet with Theophylline, could make Metpure-XL 25 Tablet less effective and enhance the effects of Theophylline.

How to manage the interaction:
Although taking Metpure-XL 25 Tablet and theophylline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Taking Metoprolol with Ceritinib together increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Metpure-XL 25 Tablet and Ceritinib, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Metpure-XL 25 Tablet:
Using saquinavir together with metoprolol can increase the risk of an irregular heart rhythm

How to manage the interaction:
Co-administration of Metpure-XL 25 Tablet with Saquinavir can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Metpure-XL 25 Tablet:
Taking Dolasetron and Metpure-XL 25 Tablet together can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Metpure-XL 25 Tablet and Dolsetron together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Co-administration of Fingolimod and Metpure-XL 25 Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although taking Metpure-XL 25 Tablet and Fingolimod together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Co-administration of Ritodrine with Metpure-XL 25 Tablet can decrease the effectiveness of both medications.

How to manage the interaction:
Although taking Metpure-XL 25 Tablet and Ritodrine together can cause an interaction, it can be taken if a doctor has suggested it. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.
  • Doing this can help lower your raised blood pressure by about 5 mm Hg.
  • Option for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease. 
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

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Alcohol

Safe if prescribed

Drinking alcohol may increase tiredness and lower blood pressure causing dizziness or drowsiness. So avoid consuming alcohol with Metpure-XL 25 Tablet .

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Pregnancy

Consult your doctor

In pregnant women, no adequate and well-controlled studies exist. Metpure-XL 25 Tablet should be used only when necessary during pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Metpure-XL 25 Tablet .

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Breast Feeding

Consult your doctor

Small amounts of Metpure-XL 25 Tablet pass into the breast milk and do not cause any problems for your baby. However, if you are breastfeeding, contact your doctor before taking Metpure-XL 25 Tablet .

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Driving

Safe if prescribed

You may experience dizziness, tiredness, or blurred vision while taking Metpure-XL 25 Tablet . So, it is not recommended to drive, use machinery, or perform other tasks.

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Liver

Consult your doctor

Metpure-XL 25 Tablet to be taken with caution if you have pre-existing or a history of liver disease/conditions. Your doctor may adjust the dose based on your condition.

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Kidney

Consult your doctor

Metpure-XL 25 Tablet is probably safe to use in patients with kidney disease. Please consult your doctor before using Metpure-XL 25 Tablet .

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Children

Safe if prescribed

The safety and efficacy of Metpure-XL 25 Tablet in children have not been established. Hence, Metpure-XL 25 Tablet is not recommended for children.

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Heart

Metpure-XL 25 Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Metpure-XL 25 Tablet .

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Geriatrics

Consult your doctor

Metpure-XL 25 Tablet should be given cautiously to elderly patients, starting with a lower dose due to possible reduced organ function. Seek medical advice if you have any concerns.

FAQs

Metpure-XL 25 Tablet is used to treat high blood pressure (hypertension), heart-related chest pain (angina), and heart rhythm disorder (arrhythmia). Besides this, it also helps in relieving symptoms of migraine-related headaches.

Metpure-XL 25 Tablet contains S-Metoprolol Succinate, which helps to reduce blood pressure by allowing the blood to flow more smoothly.

Use of Metpure-XL 25 Tablet in diabetes may mask tachycardia (fast heart rate) occurring with low blood sugar level, but other symptoms like dizziness and sweating may not be significantly affected. So, if you are a diabetic patient, always consult a doctor before taking Metpure-XL 25 Tablet .

Serum sodium, serum potassium, white blood cells, and kidney or renal function should be closely monitored before taking Metpure-XL 25 Tablet .

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

Metpure-XL 25 Tablet can increase blood potassium levels. So a potassium-rich diet and supplements should be avoided while taking Metpure-XL 25 Tablet to avoid any unpleasant side effects.

Stopping Metpure-XL 25 Tablet abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose over time to help prevent these symptoms. Please consult the doctor before stopping Metpure-XL 25 Tablet .

Metpure-XL 25 Tablet may cause dizziness and tiredness; drive or operate machinery only if you are alert. Drinking alcohol may increase tiredness and lower blood pressure causing dizziness or drowsiness. So, avoid consuming alcohol with Metpure-XL 25 Tablet . Orthostatic hypotension (sudden lowering of blood pressure while standing) might occur, so patients using Metpure-XL 25 Tablet should get up with caution.

Let the doctor know if you have very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. Consult the doctor if you are pregnant or breastfeeding.

Metpure-XL 25 Tablet starts working within 1 hour. However, it might take a week to take full effect.

No, it is safe to take Metpure-XL 25 Tablet if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.

Metpure-XL 25 Tablet does not help you sleep better. It is used to treat hypertension (high blood pressure), angina (heart-related chest pain), arrhythmia (heart rhythm disorder), heart failure, stroke, and migraine.

Drinking alcohol may increase tiredness and lower blood pressure causing dizziness or drowsiness. So, avoid consuming alcohol with Metpure-XL 25 Tablet .

Metpure-XL 25 Tablet may cause side effects such as headache, fatigue, nausea, vomiting, stomach upset, diarrhoea or constipation, abdominal pain, numbness, and cold extremities. Most of these side effects of Metpure-XL 25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - MET0043

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