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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Metpure-XL 25 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure, arrhythmia, and angina pectoris. This medicine also helps reduce the chances of heart problems such as heart attack and stroke. This medicine contains bisoprolol which alters the response to nerve impulses in the heart thereby making the heart pump blood easier. Common side effects include headache, fatigue, nausea, vomiting, stomach upset, diarrhoea or constipation, abdominal pain, numbness, and cold extremities.
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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Metpure-XL 25 Tablet

Metpure-XL 25 Tablet is used alone or together with other medicines to treat high blood pressure (hypertension), heart-related chest pain (angina), and heart rhythm disorder (arrhythmia). Besides this, it also helps in relieving symptoms of migraine-related headaches. High blood pressure adds to the workload of the heart and arteries. Hypertension or high blood pressure is a long-term force of the blood against the arteries that may lead to various types of heart diseases. If it continues for a long time, it can damage the blood vessels (arteries) of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure reduces the risk of stroke, heart attack, and heart-related chest pain (angina).

Metpure-XL 25 Tablet contains S Metoprolol Succinate. It plays a vital role in relaxing our blood vessels by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier to pump more blood around your body. This lowers your blood pressure and helps reduce your risk of a stroke, a heart attack, other heart problems, or kidney problems in the future. Metpure-XL 25 Tablet needs to be taken regularly to be effective.

Metpure-XL 25 Tablet should be taken in the dose and duration your doctor advises. You are advised to take Metpure-XL 25 Tablet for as long as your doctor has prescribed, depending on your medical condition. In some cases, you may experience common side effects such as headache, fatigue, nausea, vomiting, stomach upset, diarrhoea or constipation, abdominal pain, numbness, and cold extremities. Most of these side effects of Metpure-XL 25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. However, you are advised to talk to your doctor if you experience these side effects persistently.

Don't stop taking Metpure-XL 25 Tablet without consulting your doctor first. Stopping Metpure-XL 25 Tablet abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose over time to help prevent these symptoms. Metpure-XL 25 Tablet should not be used to prevent heart attacks. You should not use Metpure-XL 25 Tablet if you have a very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. Pregnant and breastfeeding women should consult the doctor before taking the Metpure-XL 25 Tablet . Driving and operating heavy machinery should not be done as it may cause dizziness and drowsiness.  Orthostatic hypotension (sudden lowering of blood pressure while standing) might occur, so patients using Metpure-XL 25 Tablet should get up with caution. Metpure-XL 25 Tablet is contraindicated if you have high amounts of potassium in your blood (shown in blood test results). Metpure-XL 25 Tablet may affect your ability to drive or operate heavy machinery if taken with alcohol.

Uses of Metpure-XL 25 Tablet

Treatment of Hypertension (high blood pressure), Angina (heart-related chest pain), Arrhythmia (heart rhythm disorder), Heart failure, Stroke, and Migraine

Directions for Use

Swallow the tablet with a glass of water as a whole. Do not crush, break, or chew the tablet. Metpure-XL 25 Tablet can be taken with or without food. Take Metpure-XL 25 Tablet as prescribed by your doctor. Metpure-XL 25 Tablet should not be taken unless prescribed by a doctor. Based on your medical condition, your doctor will advise on how long you need to take Metpure-XL 25 Tablet .

Medicinal Benefits

Metpure-XL 25 Tablet contains S Metoprolol Succinate belongs to a group of medicines called beta-blockers used to treat high blood pressure (hypertension), heart-related chest pain (angina), irregular heart rhythm (arrhythmia), and to protect the heart after a heart attack (myocardial infarction). Besides this, it also helps relieve symptoms of migraine-related headaches. Metpure-XL 25 Tablet  helps slow down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future. 

How Metpure-XL 25 Tablet Works

Metpure-XL 25 Tablet contains S Metoprolol Succinate. It plays a vital role in relaxing our blood vessels by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier to pump more blood around your body. This lowers your blood pressure and helps reduce your risk of a stroke, a heart attack, other heart problems, or kidney problems in the future. Metpure-XL 25 Tablet needs to be taken regularly to be effective.

Storage

Store in a cool and dry place away from sunlight
Side effects of Metpure-XL 25 Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Metpure-XL 25 Tablet

Take Metpure-XL 25 Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include severe low blood pressure, nausea, vomiting, sinus bradycardia (slow heart rate), atrioventricular block (delay in transmission of an impulse from atria to ventricles), cardiogenic shock (inability of the heart to supply blood and oxygen), heart failure, bronchospasm (tightening of airway muscles), cardiac arrest (abrupt loss of heart function), cyanosis (bluish-purple colour of skin), and impairment of consciousness/coma. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Metpure-XL 25 Tablet if you are allergic (hypersensitive) to the Metpure-XL 25 Tablet or any ingredients present. Please consult your doctor before taking Metpure-XL 25 Tablet if you are pregnant or planning to conceive and breastfeed. It should not be given to children less than 12 years of age. Don't stop taking Metpure-XL 25 Tablet without talking to your doctor first. Stopping Metpure-XL 25 Tablet gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over some time to help prevent these symptoms. You should not use the Metpure-XL 25 Tablet if you have a very slow heartbeat, a serious lung condition (like asthma), a serious heart condition (sick sinus syndrome), or a heart blockage. Before taking this medicine, you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problems (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder like overactive thyroid (hyperthyroidism), adrenal gland cancer, or severe blood circulation problem (Raynaud's syndrome).

Drug-Drug Interactions

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MetoprololSaquinavir
Severe

Drug-Drug Interactions

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How does the drug interact with Metpure-XL 25 Tablet:
Coadministration of Metpure-XL 25 Tablet and Tizanidine may reduce the efficiency of Metpure-XL 25 Tablet.

How to manage the interaction:
Taking Metpure-XL 25 Tablet and Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.
MetoprololSaquinavir
Severe
How does the drug interact with Metpure-XL 25 Tablet:
Using Metpure-XL 25 Tablet and Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Metpure-XL 25 Tablet and Saquinavir, but they can be taken together if your doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Co-administration of Clonidine and Metpure-XL 25 Tablet may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metpure-XL 25 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Use of Metpure-XL 25 Tablet with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Metpure-XL 25 Tablet and Atazanavir, it can be taken if prescribed by the doctor. Consult the doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Taking ceritinib together with Metpure-XL 25 Tablet can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Metpure-XL 25 Tablet and Ceritinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololAcebutolol
Severe
How does the drug interact with Metpure-XL 25 Tablet:
Coadministration of Acebutolol with Metpure-XL 25 Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Metpure-XL 25 Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Coadministration of Aminophylline with Metpure-XL 25 Tablet together can make Metpure-XL 25 Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Metpure-XL 25 Tablet may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Coadministration of Metpure-XL 25 Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Metpure-XL 25 Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Metpure-XL 25 Tablet:
Both Metpure-XL 25 Tablet and Artemether may increase the blood levels and effects of Metpure-XL 25 Tablet activity.

How to manage the interaction:
Taking Metpure-XL 25 Tablet and Artemether together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metpure-XL 25 Tablet:
Coadministration of Metpure-XL 25 Tablet with Diltiazem can increase the side effects.

How to manage the interaction:
Although there is a possible interaction between Metpure-XL 25 Tablet and Diltiazem, you can take these medicines together if prescribed by your doctor. Consult your doctor immediately if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.

  • Doing this can help lower your raised blood pressure by about 5 mm Hg.

  • Option for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, only one serving for women and two servings for men is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease. 

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, immediately contact your doctor.

  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Caution

Drinking alcohol may increase tiredness and lower blood pressure causing dizziness or drowsiness. So avoid consuming alcohol with Metpure-XL 25 Tablet .

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Pregnancy

Caution

In pregnant women, no adequate and well-controlled studies exist. Metpure-XL 25 Tablet should be used only when necessary during pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Metpure-XL 25 Tablet .

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Breast Feeding

Caution

Small amounts of Metpure-XL 25 Tablet pass into the breast milk and do not cause any problems for your baby. However, if you are breastfeeding, contact your doctor before taking Metpure-XL 25 Tablet .

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Driving

Caution

You may experience dizziness, tiredness, or blurred vision while taking Metpure-XL 25 Tablet . So, it is not recommended to drive, use machinery, or perform other tasks.

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Liver

Caution

Metpure-XL 25 Tablet to be taken with caution if you have pre-existing or a history of liver disease/conditions. Your doctor may adjust the dose based on your condition.

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Kidney

Safe if prescribed

Metpure-XL 25 Tablet is probably safe to use in patients with kidney disease. Please consult your doctor before using Metpure-XL 25 Tablet .

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Children

Unsafe

The safety and efficacy of Metpure-XL 25 Tablet in children have not been established. Hence, Metpure-XL 25 Tablet is not recommended for children.

Have a query?

FAQs

Metpure-XL 25 Tablet is used to treat high blood pressure (hypertension), heart-related chest pain (angina), and heart rhythm disorder (arrhythmia). Besides this, it also helps in relieving symptoms of migraine-related headaches.

Metpure-XL 25 Tablet contains S Metoprolol Succinate, which helps to reduce blood pressure by allowing the blood to flow more smoothly. It is an extended-release medication, its active ingredient is released slowly over time into the body, so you will typically only need to take the Metpure-XL 25 Tablet once a day.

Use of Metpure-XL 25 Tablet in diabetes may mask tachycardia (fast heart rate) occurring with low blood sugar level, but other symptoms like dizziness and sweating may not be significantly affected. So, if you are a diabetic patient, always consult a doctor before taking Metpure-XL 25 Tablet .

Serum sodium, serum potassium, white blood cells, and kidney or renal function should be closely monitored before taking Metpure-XL 25 Tablet .

Serum sodium, potassium, white blood cells, and kidney or renal function should all be properly evaluated before taking Metpure-XL 25 Tablet .

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

Metpure-XL 25 Tablet can increase blood potassium levels. So a potassium-rich diet and supplements should be avoided while taking Metpure-XL 25 Tablet to avoid any unpleasant side effects.

Stopping Metpure-XL 25 Tablet abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose over time to help prevent these symptoms. Please consult the doctor before stopping Metpure-XL 25 Tablet .

Metpure-XL 25 Tablet may cause dizziness and tiredness; drive or operate machinery only if you are alert. Drinking alcohol may increase tiredness and lower blood pressure causing dizziness or drowsiness. So, avoid consuming alcohol with Metpure-XL 25 Tablet . Orthostatic hypotension (sudden lowering of blood pressure while standing) might occur, so patients using Metpure-XL 25 Tablet should get up with caution.

Let the doctor know if you have very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. Consult the doctor if you are pregnant or breastfeeding.

Metpure-XL 25 Tablet starts working within 2 hours. However, it might take a week to take full effect.

No, it is safe to take Metpure-XL 25 Tablet if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.

Metpure-XL 25 Tablet does not help you sleep better. It is used to treat hypertension (high blood pressure), angina (heart-related chest pain), arrhythmia (heart rhythm disorder), heart failure, stroke, and migraine.

Drinking alcohol may increase tiredness and lower blood pressure causing dizziness or drowsiness. So, avoid consuming alcohol with Metpure-XL 25 Tablet .

Metpure-XL 25 Tablet may cause side effects such as headache, fatigue, nausea, vomiting, stomach upset, diarrhoea or constipation, abdominal pain, numbness, and cold extremities. Most of these side effects of Metpure-XL 25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - MET0043

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