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  3. Metris 0.5% Inj 100Ml (Otsuka)

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Metris 0.5% Inj 100Ml (Otsuka), Pack of 1
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Extra 15% Off with Bank Offers

Composition :

METRONIDAZOLE-500MG

Manufacturer/Marketer :

Otsuka Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Metris 0.5% Inj 100Ml (Ot

Metris 0.5% Inj 100Ml (Ot belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). 

Metris 0.5% Inj 100Ml (Ot contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thus, Metris 0.5% Inj 100Ml (Ot treats bacterial infections.

Metris 0.5% Inj 100Ml (Ot will be administered by a healthcare professional; do not self-administer. Some common side effects of Metris 0.5% Inj 100Ml (Ot are nausea, vomiting, diarrhoea, constipation, and injection site reaction. These side effects are temporary and may resolve after some time. However, if any of the side effects persist or worsen, contact the doctor.

Let your doctor know if you are allergic to metronidazole. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metris 0.5% Inj 100Ml (Ot as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Metris 0.5% Inj 100Ml (Ot as it may cause unpleasant side effects.

Uses of Metris 0.5% Inj 100Ml (Ot

Metris 0.5% Inj 100Ml (Ot used in the treatment of bacterial infections. The detailed uses of Metris 0.5% Inj 100Ml (Ot are as follows: <br/>• Treatment of Infections: Metris 0.5% Inj 100Ml (Ot effectively treats various infections, including intra-abdominal, skin, gynecologic, septicemia, bone and joint, CNS, respiratory tract, and endocarditis, by eliminating anaerobic bacteria and parasites, stopping their growth, and alleviating symptoms.<br/>• Surgical Prophylaxis: Metris 0.5% Inj 100Ml (Ot is used as a surgical prophylaxis to prevent postoperative infections, particularly for surgeries involving the gastrointestinal tract.<br/>• Management of Clostridium Difficile Infection: Metris 0.5% Inj 100Ml (Ot is used to manage severe Clostridium difficile infections, especially when oral medication is not possible.<br/>• Amoebic Dysentery Treatment: Metris 0.5% Inj 100Ml (Ot is used to treat amoebic dysentery, a severe intestinal infection caused by the Entamoeba histolytica parasite.<br/>• Combination Therapy: Metris 0.5% Inj 100Ml (Ot is often used in combination with other antibiotics to treat serious infections, offering a broad spectrum of action and enhancing treatment effectiveness.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Metris 0.5% Inj 100Ml (Ot will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Metris 0.5% Inj 100Ml (Ot belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, gynecologic, respiratory infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). Metris 0.5% Inj 100Ml (Ot contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby, Metris 0.5% Inj 100Ml (Ot treats bacterial infections.

How Metris 0.5% Inj 100Ml (Ot Works

Metris 0.5% Inj 100Ml (Ot contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thus, Metris 0.5% Inj 100Ml (Ot treats bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Metris 0.5% Inj 100Ml (Otsuka)
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Eat a balanced diet rich in fruits, vegetables, and whole grains to support overall health.
  • Include foods high in omega-3 fatty acids, like salmon and walnuts, to support eye health.
  • Stay hydrated by drinking plenty of water.
  • Engage in regular physical activity, like walking or yoga, to improve mobility and balance.
  • Practice stress-reducing techniques, like meditation or deep breathing, to manage emotional challenges.
  • Establish a daily routine to maintain independence and organization.
  • Consider learning Braille or using assistive technologies to enhance daily life.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • To the affected part, apply warm compresses to get a temporary relief.
  • Rinse your eye carefully with clean water and try to blow any dust particle that could have entered.
  • Take over the counter medication to lubricate your eye or if there is pain due to allergy to soothe the eye.
  • If there is persistent pain in your eye, consult your doctor and follow the medication immediately.

What if I have taken an overdose of Metris 0.5% Inj 100Ml (Ot

A health care professional administers Metris 0.5% Inj 100Ml (Ot in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include nausea, vomiting, loss of muscle coordination, numbness, pain, burning, or tingling in your hands or feet, and seizures. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Metris 0.5% Inj 100Ml (Ot if you are allergic to any of the components. Consult your doctor if you are pregnant, plan to get pregnant or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metris 0.5% Inj 100Ml (Ot as it may cause dizziness and drowsiness. Inform your doctor if you have bone marrow depression/low blood count, kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, epilepsy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical
MetronidazoleEthanol
Critical

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical
How does the drug interact with Metris 0.5% Inj 100Ml (Otsuka):
Co-administration of Amprenavir with Metris 0.5% Inj 100Ml (Otsuka) can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metris 0.5% Inj 100Ml (Otsuka) with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleEthanol
Critical
How does the drug interact with Metris 0.5% Inj 100Ml (Otsuka):
Drinking alcohol while taking Metris 0.5% Inj 100Ml (Otsuka) can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metris 0.5% Inj 100Ml (Otsuka) with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleDisulfiram
Critical
How does the drug interact with Metris 0.5% Inj 100Ml (Otsuka):
Coadministration of Disulfiram with Metris 0.5% Inj 100Ml (Otsuka) can increase the risk of side effects.

How to manage the interaction:
Taking Metris 0.5% Inj 100Ml (Otsuka) and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
MetronidazoleBusulfan
Severe
How does the drug interact with Metris 0.5% Inj 100Ml (Otsuka):
Coadministration of Busulfan and Metris 0.5% Inj 100Ml (Otsuka) may increase the risk of side effects.

How to manage the interaction:
Taking Metris 0.5% Inj 100Ml (Otsuka) and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
MetronidazoleWarfarin
Severe
How does the drug interact with Metris 0.5% Inj 100Ml (Otsuka):
Coadministration of Metris 0.5% Inj 100Ml (Otsuka) with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Metris 0.5% Inj 100Ml (Otsuka) and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
MetronidazoleMebendazole
Severe
How does the drug interact with Metris 0.5% Inj 100Ml (Otsuka):
Coadministration of Metris 0.5% Inj 100Ml (Otsuka) with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Metris 0.5% Inj 100Ml (Otsuka) and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MetronidazoleFluconazole
Moderate
How does the drug interact with Metris 0.5% Inj 100Ml (Otsuka):
Co-administration of Fluconazole together with Metris 0.5% Inj 100Ml (Otsuka) can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Metris 0.5% Inj 100Ml (Otsuka) with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Metris 0.5% Inj 100Ml (Ot to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet. This food can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should also be included in the diet.
  • Avoid intake of alcoholic beverages with Metris 0.5% Inj 100Ml (Ot as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Metris 0.5% Inj 100Ml (Ot in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Metris 0.5% Inj 100Ml (Ot Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Metris 0.5% Inj 100Ml (Ot to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.

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Pregnancy

Caution

Please consult your doctor. Metris 0.5% Inj 100Ml (Ot should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Metris 0.5% Inj 100Ml (Ot.

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Driving

Caution

Metris 0.5% Inj 100Ml (Ot may cause dizziness and drowsiness; thus, avoid operating machinery or driving vehicles unless you are alert.

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Liver

Caution

Metris 0.5% Inj 100Ml (Ot to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your liver condition.

bannner image

Kidney

Caution

Metris 0.5% Inj 100Ml (Ot to be taken with extreme caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your kidney condition.

bannner image

Children

Consult your doctor

Limited information about the use of Metris 0.5% Inj 100Ml (Ot in paediatric patients. Please seek medical advice. Your doctor will weigh the benefits and risks before prescribing this medicine to your child.

FAQs

Metris 0.5% Inj 100Ml (Ot belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves).

Metris 0.5% Inj 100Ml (Ot suppresses protein synthesis by interacting with DNA, causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms, treating bacterial infections.

Caution should be exercised. Metris 0.5% Inj 100Ml (Ot may enhance the anticoagulant activity of warfarin and other oral anticoagulants by extending prothrombin time. Inform your doctor if you are taking such medications.

No. Metris 0.5% Inj 100Ml (Ot is an antibacterial medicine that acts only against bacterial infections, not viral infections like the common cold and flu.

Metris 0.5% Inj 100Ml (Ot should only be used to treat or prevent infections that have been proven or are strongly suspected to be caused by susceptible anaerobic bacteria.

Extreme caution should be exercised while using Metris 0.5% Inj 100Ml (Ot in patients with severe liver damage, blood formation disorder, brain, spinal cord or nervous disease. So, let your doctor know if you have any of these conditions.

Country of origin

India

Manufacturer/Marketer address

401, Abhishree Complex, Opp: Om Tower, Beside Bidiwala Park, Satellite Road, Ahmedabad 380 015, Gujarat, India
Other Info - MET2016

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 7:01 AM IST

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Reference

  1. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d46870f5-e2b1-46bd-8413-4a0a8bcf3175&amp;type=display
  2. https://www.medicines.org.uk/emc/files/pil.13293.pdf
  3. https://www.medicines.org.uk/emc/product/1842/smpc#gref
  4. https://www.nhs.uk/medicines/metronidazole/about-metronidazole/
  5. https://www.drugs.com/drug-interactions/metronidazole-index.html?filter=3

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