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compositionComposition:CHLORHEXIDINE-0.25%W/W+METRONIDAZOLE-1%W/W
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Prescription Medicine
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METROGYL DG GEL is used for the treatment of gum diseases like gum inflammation (gingivitis) and prevention of dental plaque. It contains Metronidazole and Chlorhexidine, which kills oral bacteria that cause plaque and forms a protective antibacterial layer over gums and teeth for the prevention of plaque formation. As a result, it helps in maintaining good oral and dental hygiene. It may cause common side effects such as metallic taste, bitter taste, burning, transient redness, irritation, dryness, and staining of teeth. Maintain good oral hygiene and brush at least 2 times a day to avoid any oral infection and its spread. Do not rinse the mouth or drink or eat anything for 30 minutes after applying this.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHLORHEXIDINE-0.25%W/W+METRONIDAZOLE-1%W/W

Manufacturer/Marketer :

J B Chemicals & Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About METROGYL DG GEL

METROGYL DG GEL is a specialised oral topical medication prescribed to treat bacterial infections in the mouth, such as gum disease and mouth ulcers. It helps reduce swelling, redness, and discomfort in the oral cavity by targeting the harmful microbes that cause these issues. This medicine is designed specifically to help restore and maintain your overall oral health.

To get the best results, you must use METROGYL DG GEL exactly as directed by your healthcare provider. For maximum effectiveness, do not eat, drink, or brush your teeth immediately after applying this medication. Combining this treatment with regular, gentle brushing and flossing can significantly speed up your recovery.

While using METROGYL DG GEL, you may experience mild and temporary side effects, such as a metallic taste in your mouth or slight irritation. However, if you experience severe burning, swelling of the mouth, or signs of an allergic reaction, stop using it immediately and contact your doctor. Always seek professional advice if you notice any unusual symptoms during your treatment.

Do not take this if you have a known allergy to any of the active ingredients in METROGYL DG GEL. Before starting this medication, tell your doctor if you have a history of blood disorders, nerve problems, or liver damage. This helps ensure the medicine is safe and appropriate for your specific health profile.

Although this medicine is applied locally in the mouth and only small amounts usually enter the bloodstream, interactions associated with metronidazole may still be a concern if significant amounts are swallowed. Inform your doctor about all medicines you are taking and discuss alcohol use during treatment. If you are pregnant, planning to become pregnant, breastfeeding, or an older adult, consult your doctor before using this medicine. 

Uses of METROGYL DG GEL

METROGYL DG GEL may be prescribed for the following oral conditions: 

  • Gum disease (gingivitis and periodontitis): METROGYL DG GEL helps clear up bacterial infections in the gums, reducing swelling, bleeding, and tenderness.
  • Mouth ulcers: It protects painful sores in the mouth from secondary bacterial infections, allowing them to heal much faster.
  • Dental plaque buildup: It works to control and reduce the accumulation of harmful plaque-causing bacteria on your teeth and gums.

Key Benefits

METROGYL DG GEL helps treat bacterial infections of the gums and oral tissues by reducing harmful bacteria and supporting the healing process.

  • Reduces Gum Infection: Helps eliminate bacteria responsible for gum infections and other oral infections.
  • Relieves Oral Discomfort: Helps reduce pain, swelling, tenderness, and bleeding associated with infected gums.
  • Supports Oral Healing: Promotes healing of affected gum tissues by controlling infection and inflammation.
  • Provides Long-Lasting Antibacterial Protection: The active ingredients remain on the teeth and gums for an extended period, helping control bacterial growth between applications.
  • Helps Prevent Infection Spread: Reduces the risk of the infection spreading to deeper oral tissues and surrounding areas.
     

Directions for Use

Follow these step-by-step instructions to ensure you use METROGYL DG GEL correctly and safely:

  • Rinse your mouth gently with water to clear away any loose food particles before application.
  • Apply the prescribed amount of gel or solution to the affected areas of your gums or mouth using a clean finger, a soft toothbrush, or a cotton swab.
  • Do not swallow the medication; spit out any excess gel or liquid after application.
  • Avoid rinsing your mouth, drinking water, or eating meals for at least 30 minutes after using the medicine to allow it to work effectively.

Always follow your doctor's exact instructions regarding how much to use and how often to apply it.

How METROGYL DG GEL Works

METROGYL DG GEL contains metronidazole and chlorhexidine, which work together to treat infections of the gums and oral tissues. Metronidazole is an antimicrobial medicine that enters susceptible bacterial cells and damages their genetic material, preventing them from growing and multiplying. Chlorhexidine is a broad-spectrum antiseptic that attaches to the surfaces of the teeth, gums, and other tissues inside the mouth, where it helps kill a wide range of bacteria and other microorganisms. It also provides prolonged antibacterial protection, often lasting for approximately 8–12 hours, by making it harder for new bacteria to attach to oral surfaces and form plaque. Together, these actions help reduce bacterial growth, relieve inflammation, promote healing of affected tissues, and support better oral health.
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Alcohol

Caution

Please consult your doctor for more information on consuming alcohol while being treated with METROGYL DG GEL.

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Pregnancy

Caution

METROGYL DG GEL should be used during pregnancy only when prescribed by the doctor. Please consult your doctor before taking METROGYL DG GEL if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Please consult your doctor before taking METROGYL DG GEL if you are breastfeeding.

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Driving

Safe if prescribed

METROGYL DG GEL usually does not interfere with your driving ability.

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Liver

Safe if prescribed

METROGYL DG GEL can be given in case of any liver impairment or problem.

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Kidney

Safe if prescribed

METROGYL DG GEL can be given in case of any kidney impairment or problem.

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Children

Caution

Children below the age of 12 years should not use METROGYL DG GEL. In children above the age of 12 years, METROGYL DG GEL should be taken only if prescribed by a child specialist.

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Heart

Consult your doctor

Please consult your doctor if you have any concerns regarding the usage of METROGYL DG GEL in heart patients.

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Geriatrics

Consult your doctor

Please consult a doctor before giving METROGYL DG GEL to geriatric patients. Your doctor will prescribe METROGYL DG GEL if the benefits outweigh the risks.

What if I have taken an overdose of METROGYL DG GEL

The overdose of METROGYL DG GEL is unlikely. However, if you suspect any adverse reactions or unusual symptoms, please consult your doctor.

Diet & Lifestyle Advise

  • Avoid alcohol completely: Do not consume alcohol during your treatment and for at least three days after your final dose to prevent severe nausea, vomiting, and headaches.
  • Practice good oral hygiene: Brush your teeth twice a day with a soft-bristled brush and floss daily, but be extremely gentle around infected or inflamed gums.
  • Limit sugary foods: Reduce your intake of sugary snacks and acidic drinks, as these can feed harmful mouth bacteria and slow down your healing process.
  • Stay hydrated: Drink plenty of water throughout the day to help wash away food debris and keep your mouth moist, but remember to wait 30 minutes after applying METROGYL DG GEL before drinking.
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How Soon It Starts Working

The time required for METROGYL DG GEL to start to work: METROGYL DG GEL ideally shows its action within few hours after administration. The time for which the effects of METROGYL DG GEL last: The duration of action for METROGYL DG GEL is not clinically established.

What if you forget to take METROGYL DG GEL

Use the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not use a double dose to make up for the missed one.

Storage

Store METROGYL DG GEL at room temperature, ideally between 15°C and 30°C. Keep the container tightly closed and protect it from direct sunlight, high heat, and moisture.

Drug Warnings

  • Check Before Use: Inspect the packaging before use and do not use the product if the safety seal is broken, damaged, or if the gel appears discoloured.
  • Avoid Contact with Eyes: Keep the medicine away from your eyes. If accidental contact occurs, rinse thoroughly with plenty of clean water.
  • Do Not Share the Medication: Do not share METROGYL DG GEL with others, even if they have similar oral symptoms.
  • Monitor Your Symptoms: Consult your dentist or doctor if your symptoms do not improve after a few days of regular use or if they become worse.

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Drug-Drug Interactions

Because METROGYL DG GEL is used locally in the mouth, systemic absorption is generally low. However, clinically relevant interactions may occur if significant amounts are swallowed or absorbed. Inform your doctor if you are taking any of the following medicines: 

  • Blood thinners: Using METROGYL DG GEL alongside medications like warfarin may increase the risk of bleeding. Your doctor may need to monitor your blood clotting times closely.
  • Disulfiram: Taking this medication with disulfiram may cause serious mental disturbances, including severe confusion, hallucinations, or unusual behaviour. Avoid using them together unless advised by your doctor.

Drug-Food Interactions

Certain foods and beverages may affect how METROGYL DG GEL works or increase the risk of side effects:

  • Alcohol: Although the risk is lower with topical oral use than with oral metronidazole tablets, avoiding alcohol during treatment is recommended. If significant amounts of the medicine are swallowed, alcohol may increase the risk of unpleasant effects such as flushing, headache, nausea, or vomiting. 

Drug-Disease Interactions

Inform your doctor if you have any of the following conditions before using METROGYL DG GEL, as additional monitoring may be required: 

  • Liver disease: If you have severe liver damage, your body may process this medication much slower, increasing the risk of side effects.
  • Nervous system disorders: Use this medicine with caution if you have a history of neurological conditions, as some ingredients may cause numbness or tingling.
     

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS- TOPICAL ANTIBIOTICS/ANTIMICROBIALS]

FAQs

METROGYL DG GEL is used for the treatment of gum diseases like gum inflammation (gingivitis) and prevention of dental plaque.
METROGYL DG GEL contains Metronidazole and Chlorhexidine. It kills oral bacteria that cause plaque and forms a protective antibacterial layer over gums and teeth for the prevention of plaque formation. As a result, it helps in maintaining good oral and dental hygiene.Â
A bitter taste may be one of the side effects of METROGYL DG GEL. It is temporary and usually gets resolved after you stop using the medicine.
Brush your teeth twice a day with a soft-bristled brush. floss your teeth once a day to remove the plaque between your teeth. Do not skip your dental appointments and always use the medications as prescribed. Limit smoking and chewing tobacco. Having a professional dental cleaning twice a year can effectively manage and prevent various gum diseases.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Store METROGYL DG GEL in a cool place. Protect from light. Do not freeze. Keep it out of reach of children. METROGYL DG GEL should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.
METROGYL DG GEL causes side effects such as bitter taste, burning sensation, irritation, dryness, staining of teeth and metallic taste. Please consult a doctor immediately if any of these side effects persist longer.
Because METROGYL DG GEL is applied locally in the mouth, the risk of alcohol-related interactions is lower than with oral metronidazole tablets. However, avoiding alcohol during treatment is generally recommended, particularly if there is a possibility of swallowing the medicine. Talk to your doctor if you have questions about alcohol use while receiving treatment.
METROGYL DG GEL may cause temporary staining of the teeth, tongue, or dental fillings. This staining is usually harmless and can be removed by your dentist during a professional cleaning. Talk to your doctor or dentist if you are concerned about discolouration.
You should avoid eating, drinking, or rinsing your mouth for at least 30 minutes after applying the medication. This ensures that the active ingredients stay on your gums and teeth long enough to work effectively. Talk to your doctor for specific instructions.
You should only use METROGYL DG GEL during pregnancy if your doctor determines that the benefits outweigh the potential risks. Always discuss your pregnancy status with your healthcare provider before starting this treatment. Talk to your doctor for personalised advice.
Swallowing a tiny amount during normal oral application is generally harmless. However, if a large quantity is swallowed, it can cause stomach upset or more serious issues. Contact your doctor or seek emergency medical help immediately in such cases.
No, METROGYL DG GEL is specifically formulated to treat localised gum infections, dental plaque, and mouth ulcers. It is not designed to treat deep throat infections or systemic illnesses. Talk to your doctor to get an appropriate prescription for a throat infection.
Many patients begin to feel relief from swelling and discomfort within a few days of consistent use. However, you must complete the full course of treatment prescribed by your doctor, even if your symptoms disappear early. Talk to your doctor if your condition does not improve.
Yes, you can continue to brush with your regular toothpaste, but do not do so immediately after applying METROGYL DG GEL. Keep a gap of at least 30 minutes between brushing your teeth and applying this medication so it does not wash away. Talk to your doctor or dentist for optimal oral care tips.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Health Service (NHS). Metronidazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Gum Disease - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Connor B. Weir; Jacqueline K. Le. Metronidazole. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. [Revised in April 2022] [Accessed on 19th July 2022]Check here
  4. Gabriel B. Beecham, Trevor A. Nessel, Amandeep Goyal. Lidocaine. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. [Revised in December 2021] [Accessed on 19th July 2022]Check here
  5. Purna Pharmaceuticals NV. Electronic Medicines Compendium (EMC). [Revised in May 2020] [Accessed on 19th July 2022]Check here
  6. Galderma Production Canada, Inc. Food & Drug Administration (FDA). [Accessed on 19th July 2022] docs/label/2005/021789lbl.pdfCheck here

Country of origin

India

Manufacturer/Marketer address

Cnergy IT Park, 3rd floor Appa Saheb Marathe Marg, Prabhadevi, Mumbai 400025
Other Info - MET0050
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