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compositionComposition:METRONIDAZOLE
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Metron 100ml I.V. is an antibacterial medication used in the treatment of bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis, and endocarditis. This medicine inhibits the bacterial growth by destroying the DNA of the infection causing bacteria. You may experience common side effcts like nausea, vomiting, diarrhoea, constipation, and injection site reaction.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

METRONIDAZOLE

Manufacturer/Marketer :

Apple Pharmaceuticals

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Metron 100ml I.V.

Metron 100ml I.V. is a specialised injection used to treat serious infections caused by certain bacteria and parasites. It is commonly prescribed for severe abdominal, bone, skin, and pelvic infections. Doctors also give this medicine before specific surgeries to prevent infections from developing in the first place.

Because this medicine is given directly into a vein, healthcare professionals usually manage your schedule to ensure it is given at consistent times. It is vital to complete the entire course exactly as prescribed, even if you start feeling better. Drinking plenty of water during your treatment is a simple lifestyle change that helps support your kidneys and promotes a smoother recovery.

While using Metron 100ml I.V. , you may experience mild side effects like a metallic taste in your mouth, nausea, or a headache. However, you should contact your doctor immediately if you experience serious symptoms, such as numbness or tingling in your hands or feet, or severe, watery diarrhoea.

Before receiving this medicine, tell your doctor if you have a history of liver disease, kidney problems, or nerve disorders. Do not take this medicine if you have had an allergic reaction to similar infection-fighting medications in the past.

Avoid drinking alcohol during your treatment and for at least three days after your final dose, as combining them can cause severe nausea, rapid heart rate, and vomiting. You should also tell your doctor if you take blood thinners or lithium, and consult them if you are pregnant, breastfeeding, or an older adult, as your dose may need to be carefully monitored.

Uses of Metron 100ml I.V.

Your doctor may prescribe Metron 100ml I.V. to help manage the following conditions:

  • Serious abdominal infections: Metron 100ml I.V. helps clear deep-seated bacterial infections in the stomach or intestinal tract.
  • Skin and soft tissue infections: It targets and destroys bacteria causing severe skin, wound, or tissue infections.
  • Bone and joint infections: It penetrates deep into bone tissues to stop bacterial growth and support healing.
  • Gynecological infections: It treats severe pelvic and uterine infections by clearing the underlying bacterial cause.
  • Surgical prevention: It is given before certain surgeries to protect the body from potential bacterial contamination during the procedure.

Key Benefits

When used as directed as part of your treatment plan, Metron 100ml I.V. may provide the following benefits: 

  • Fast-acting relief from severe infections: Because this medicine is injected directly into the bloodstream, it begins working almost immediately. This rapid action helps lower fever, reduce pain, and control the spread of infection quickly, allowing you to start feeling better much faster than with oral medications.
  • Highly effective against hard-to-treat microbes: This medicine specifically targets anaerobic bacteria (microbes that thrive in environments with little to no oxygen). These are often difficult to clear with standard antibiotics, making this targeted treatment highly reliable for deep-tissue infections.
  • Reduces post-surgery complications: When given before surgical procedures, it significantly reduces the risk of developing a post-operative infection. This protective benefit helps ensure a safer recovery and a shorter hospital stay.
Side effects of Metron 100 Ml I.V. Fluid
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Metron 100ml I.V. will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Metron 100ml I.V. Works

Metron 100ml I.V. contains metronidazole.  It works by entering the cells of the bacteria or parasites causing the infection. Once inside, it undergoes a chemical change that allows it to bind directly to the genetic material (DNA) of these harmful microbes. By damaging their DNA and stopping them from repairing it, the medicine prevents the bacteria from multiplying and causes them to die. Since human cells do not process this medicine in the same way, it selectively targets only the infectious organisms. This specific mechanism helps your body clear the illness efficiently without harming your healthy cells.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Metron 100ml I.V. to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.

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Pregnancy

Caution

Please consult your doctor. Metron 100ml I.V. should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Metron 100ml I.V. .

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Driving

Caution

Metron 100ml I.V. may cause dizziness and drowsiness; thus, avoid operating machinery or driving vehicles unless you are alert.

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Liver

Caution

Metron 100ml I.V. to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your liver condition.

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Kidney

Caution

Metron 100ml I.V. to be taken with extreme caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your kidney condition.

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Children

Consult your doctor

Limited information about the use of Metron 100ml I.V. in paediatric patients. Please seek medical advice. Your doctor will weigh the benefits and risks before prescribing this medicine to your child.

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Heart

Caution

Metron 100ml I.V. to be taken with caution, especially if you have a history of heart diseases/conditions. Your doctor may adjust your dose depending on your liver condition.

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Geriatrics

Caution

Metron 100ml I.V. should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Metron 100ml I.V.

An overdose is highly unlikely when the medicine is injected by a trained healthcare professional. However, if you suspect an overdose or experience severe symptoms like confusion, muscle weakness, or loss of coordination, seek immediate medical attention.

Diet & Lifestyle Advise

  • Strictly avoid alcohol: Do not consume alcohol or any products containing propylene glycol during your treatment and for at least 72 hours after your final dose. This prevents a severe reaction characterised by nausea, vomiting, sweating, and rapid heart rate.
  • Stay well-hydrated: Drink plenty of water throughout the day to help your kidneys flush out the medication and keep your body hydrated during recovery.
  • Support your digestive health: Antibiotics can disrupt the natural balance of bacteria in your gut. Ask your doctor if taking a high-quality probiotic or eating fermented foods after completing your treatment is right for you.
  • Rest and recover: Give your body ample time to rest, as fighting off a serious infection requires a significant amount of energy.
health query

Have a query?

How Soon It Starts Working

The time required for Metron 100ml I.V. to start to work: Metron 100ml I.V. ideally shows its action within 1 hour after administration. The time for which the effects of Metron 100ml I.V. last: The effect of Metron 100ml I.V. lasts for 12 hours.

What if you forget to take Metron 100ml I.V.

Since this medicine is given by a healthcare provider in a clinical setting, it is unlikely that you will miss a dose. However, if you are receiving treatment at home and miss a scheduled session, contact your healthcare provider or clinic immediately for advice. Do not double the dose to make up for a missed one.

Storage

• Store Metron 100ml I.V. injection at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Inspect the solution: Before use, always check the liquid in the infusion bag or vial. It should be clear and pale yellow to green-yellow; do not use it if you notice cloudiness, discolouration, or particles floating inside.
  • Monitor the injection site: Pay close attention to where the needle enters your vein. Inform your healthcare provider immediately if you notice redness, swelling, warmth, or pain at the site.
  • Complete the full course: Always complete the entire treatment plan prescribed by your doctor, even if you feel completely better. Stopping early can allow the remaining bacteria to survive and become resistant to treatment.
  • Watch for nerve symptoms: Alert your care team immediately if you experience any unusual sensations like 'pins and needles' or numbness in your fingers or toes.
  • Avoid machinery: This medicine may cause dizziness or lightheadedness. Do not drive or operate heavy machinery until you know how this medication affects you.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (like warfarin): Metron 100ml I.V. can increase the blood-thinning effects, raising your risk of bleeding.
  • Lithium: This medicine can increase lithium levels in your blood, which may lead to lithium toxicity.
  • Disulfiram: Taking this medication within 14 days of disulfiram can cause severe mental health symptoms, including confusion and hallucinations.
  • Certain anti-seizure medications (like phenytoin or phenobarbital): These can make Metron 100ml I.V. less effective or increase its side effects.
MetronidazoleAmprenavir
Critical
MetronidazoleEthanol
Critical

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical
How does the drug interact with Metron 100 Ml I.V. Fluid:
Co-administration of Amprenavir with Metron 100 Ml I.V. Fluid can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metron 100 Ml I.V. Fluid with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleEthanol
Critical
How does the drug interact with Metron 100 Ml I.V. Fluid:
Drinking alcohol while taking Metron 100 Ml I.V. Fluid can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metron 100 Ml I.V. Fluid with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleDisulfiram
Critical
How does the drug interact with Metron 100 Ml I.V. Fluid:
Coadministration of Disulfiram with Metron 100 Ml I.V. Fluid can increase the risk of side effects.

How to manage the interaction:
Taking Metron 100 Ml I.V. Fluid and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
MetronidazoleBusulfan
Severe
How does the drug interact with Metron 100 Ml I.V. Fluid:
Coadministration of Busulfan and Metron 100 Ml I.V. Fluid may increase the risk of side effects.

How to manage the interaction:
Taking Metron 100 Ml I.V. Fluid and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
MetronidazoleMebendazole
Severe
How does the drug interact with Metron 100 Ml I.V. Fluid:
Coadministration of Metron 100 Ml I.V. Fluid with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Metron 100 Ml I.V. Fluid and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MetronidazoleWarfarin
Severe
How does the drug interact with Metron 100 Ml I.V. Fluid:
Coadministration of Metron 100 Ml I.V. Fluid with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Metron 100 Ml I.V. Fluid and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Consuming alcohol or food products containing alcohol (like certain sauces or cough syrups) can cause severe stomach cramps, nausea, vomiting, headaches, and flushing.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Metron 100ml I.V. belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves).
Metron 100ml I.V. suppresses protein synthesis by interacting with DNA, causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms, treating bacterial infections.
Caution should be exercised. Metron 100ml I.V. may enhance the anticoagulant activity of warfarin and other oral anticoagulants by extending prothrombin time. Inform your doctor if you are taking such medications.
No. Metron 100ml I.V. is an antibacterial medicine that acts only against bacterial infections, not viral infections like the common cold and flu.
Metron 100ml I.V. should only be used to treat or prevent infections that have been proven or are strongly suspected to be caused by susceptible anaerobic bacteria.
Extreme caution should be exercised while using Metron 100ml I.V. in patients with severe liver damage, blood formation disorder, brain, spinal cord or nervous disease. So, let your doctor know if you have any of these conditions.
No, you must not drink alcohol while receiving Metron 100ml I.V. and for at least three days after your final dose. Doing so can cause a severe reaction with symptoms like intense nausea, vomiting, rapid heartbeat, and severe headache. Talk to your doctor if you have questions about this.
Metron 100ml I.V. is given as an intravenous infusion, meaning it is injected slowly directly into a vein. This is typically done by a healthcare professional in a clinic or hospital setting over 20 to 60 minutes. Talk to your doctor about your specific treatment plan.
If you notice any pain, swelling, redness, or warmth at the injection site, inform your nurse or doctor right away. They can inspect the area and adjust the infusion if necessary to keep you comfortable.
This medicine should only be used during pregnancy if your doctor decides it is clearly needed. If you are pregnant or planning to become pregnant, talk to your doctor or pharmacist to discuss the benefits and risks.
Metron 100ml I.V. can sometimes cause side effects like dizziness, confusion, or lightheadedness. It is best to avoid driving or operating machinery immediately after your treatment until you know exactly how the medicine affects you. Talk to your doctor if you have concerns.
Signs of a serious allergic reaction include a severe skin rash, itching, hives, swelling of your face, lips, tongue, or throat, and difficulty breathing. If you experience any of these symptoms, seek emergency medical care immediately.
Yes, but older adults may process the medication more slowly, which can increase the risk of side effects. Doctors may monitor older patients more closely or adjust their treatment plan. Talk to your doctor or pharmacist if you have concerns.

Disclaimer

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Reference

  1. DailyMed Database. Fdadrugxsl.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.13293 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. National Health Service (NHS). About Metronidazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Drugs.com Clinical Review Team. Metronidazole Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  6. Metronidazole Metronidazole. 2013. [Accessed on 29 Mar. 2019]Check here
  7. Metronidazole 500 mg Film-Coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 16 September 2025]Check here

Country of origin

India

Manufacturer/Marketer address

59, New Marine Lines, Mumbai, Maharashtra 400020
Other Info - MET0231
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